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Showing 1 to 12 of 153 entries
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Computational Characterization of Metal Binding Groups for Metalloenzyme Inhibitors.

Journal of chemical theory and computation

Dobbs KD, Rinehart AM, Howard MH, Zheng YJ, Kleier DA.
PMID: 26633058
J Chem Theory Comput. 2006 Jul;2(4):990-6. doi: 10.1021/ct050192u.

The mode of action of many pest or disease control agents involves inhibition of some metalloenzyme that is essential for the survival of the target organism. These inhibitors typically consist of a functional group that is capable of a...

Protocol for a scoping review to identify and map the global health personnel considered skilled attendants at birth in low and middle-income countries between 2000 and 2015.

BMJ open

Hobbs AJ, Moller AB, Carvajal-Aguirre L, Amouzou A, Chou D, Say L.
PMID: 29038182
BMJ Open. 2017 Oct 15;7(10):e017229. doi: 10.1136/bmjopen-2017-017229.

INTRODUCTION: Despite progress towards the Millennium Development Goals (MDG), maternal mortality remains high in countries where there are shortages of skilled personnel able to manage and provide quality care during pregnancy and childbirth. The 'percentage of births attended by...

Synthesis of Enantio- and Diastereomerically Pure, Tetra- and Penta-Substituted Cyclopentanes by the Desymmetrization of endo-Norborn-5-ene-2,3-dicarboxylic Anhydrides.

The Journal of organic chemistry

Hibbs DE, Hursthouse MB, Jones IG, Jones W, Malik KM, North M.
PMID: 11674601
J Org Chem. 1999 Jul 23;64(15):5413-5421. doi: 10.1021/jo990140v.

The desymmetrization of endo-norborn-5-ene-2,3-dicarboxylic anhydrides by methyl (S)-prolinate followed by ozonolysis of the resulting carboxylic acids is used to prepare enantio- and diastereomerically pure, tetra- and penta-substituted cyclopentane derivatives in which all of the substituents on the cyclopentane ring...

Azatriquinanes: Synthesis, Structure, and Reactivity.

The Journal of organic chemistry

Hext NM, Hansen J, Blake AJ, Hibbs DE, Hursthouse MB, Shishkin OV, Mascal M.
PMID: 11672206
J Org Chem. 1998 Aug 21;63(17):6016-6020. doi: 10.1021/jo980788s.

Azatriquinane, a tricyclic amine with rigid, hemispherical topology, is synthesized in six steps from pyrrole. This first example of a [2.2.2]cyclazine can be oxidatively dimerized to a novel, highly strained heptacycle or oxidized with chlorine to give an azatriquinacene,...

2,6-Bis[2-(4-pentylphenyl)vinyl]anthracene: a stable and high charge mobility organic semiconductor with densely packed crystal structure.

Journal of the American Chemical Society

Meng H, Sun F, Goldfinger MB, Gao F, Londono DJ, Marshal WJ, Blackman GS, Dobbs KD, Keys DE.
PMID: 16848445
J Am Chem Soc. 2006 Jul 26;128(29):9304-5. doi: 10.1021/ja062683+.

The development of new organic semiconductors with improved electrical performance and enhanced environmental stability is the focus of considerable research activity. This paper presents the design, synthesis, optical and electrochemical characterization, crystal packing, modeling and thin film morphology, and...

Discussion. Section 2: immunomodulatory intervention.

Drugs of today (Barcelona, Spain : 1998)

Catchpole B, Kavanaugh A, Hobbs K, Choy EH.
PMID: 14664237
Drugs Today (Barc). 1999 Apr-May;35(4):405-6.

No abstract available.

University of Western Ontario.

Canadian Medical Association journal

Collip JB, Hobbs GE.
PMID: 20325671
Can Med Assoc J. 1958 Apr 01;78(7):514.

No abstract available.

University of Western Ontario.

Canadian Medical Association journal

Collip JB, Hobbs GE.
PMID: 20326217
Can Med Assoc J. 1960 Apr 02;82(14):730.

No abstract available.

Current and future uses of nesiritide.

Future cardiology

Hobbs RE, Tang W.
PMID: 19804159
Future Cardiol. 2005 Mar;1(2):145-55. doi: 10.1517/14796678.1.2.145.

Nesiritide, recombinant human B-type natriuretic peptide, is an intravenous vasodilator that is used to treat acutely decompensated heart failure. In addition to its modest diuretic and natriuretic properties, nesiritide reduces intracardiac filling pressures, increases cardiac index and improves symptoms....

THE BLOOD PRESSURE AND BLOOD VESSELS IN CEREBRAL ARTERIOSCLEROSIS.

Canadian Medical Association journal

Stevenson GH, Hobbs GE.
PMID: 20319192
Can Med Assoc J. 1933 Aug;29(2):125-7.

No abstract available.

Drainage after cholecystectomy.

Annals of the Royal College of Surgeons of England

Hobbs KE.
PMID: 19310843
Ann R Coll Surg Engl. 1982 Sep;64(5):355.

No abstract available.

Consider adding this drug to fight COPD that's severe.

The Journal of family practice

Hobbs K, Brown D.
PMID: 22754891
J Fam Pract. 2012 Jul;61(7):414-6.

Daily use of azithromycin, in conjunction with the usual COPD regimen, has been found to reduce acute exacerbations in patients with moderate to severe disease.

Showing 1 to 12 of 153 entries