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Showing 1 to 12 of 60 entries
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Survival of women with cancers of breast and genital organs in Europe 1999-2007: Results of the EUROCARE-5 study.

European journal of cancer (Oxford, England : 1990)

Sant M, Chirlaque Lopez MD, Agresti R, Sánchez Pérez MJ, Holleczek B, Bielska-Lasota M, Dimitrova N, Innos K, Katalinic A, Langseth H, Larrañaga N, Rossi S, Siesling S, Minicozzi P.
PMID: 26421822
Eur J Cancer. 2015 Oct;51(15):2191-2205. doi: 10.1016/j.ejca.2015.07.022. Epub 2015 Sep 26.

BACKGROUND: Survival differences across Europe for patients with cancers of breast, uterus, cervix, ovary, vagina and vulva have been documented by previous EUROCARE studies. In the present EUROCARE-5 study we update survival estimates and investigate changes in country-specific and...

Area-Based Socioeconomic Inequalities in Colorectal Cancer Survival in Germany: Investigation Based on Population-Based Clinical Cancer Registration.

Frontiers in oncology

Jansen L, Behrens G, Finke I, Maier W, Gerken M, Pritzkuleit R, Holleczek B, Brenner H.
PMID: 32670870
Front Oncol. 2020 May 29;10:857. doi: 10.3389/fonc.2020.00857. eCollection 2020.

No abstract available.

Aβ misfolding in blood plasma measured by immuno-infrared-sensor as an age-independent risk marker of Alzheimer's disease.

Alzheimer's & dementia (Amsterdam, Netherlands)

Möllers T, Stocker H, Perna L, Nabers A, Rujescu D, Hartmann AM, Holleczek B, Schöttker B, Gerwert K, Brenner H.
PMID: 33614887
Alzheimers Dement (Amst). 2021 Feb 10;13(1):e12151. doi: 10.1002/dad2.12151. eCollection 2021.

INTRODUCTION: Determining potential risk factors of amyloid beta (Aβ) misfolding in blood, a risk marker for clinical Alzheimer's disease (AD), could have important implications for its utility in future research and clinical settings.METHODS: Participants aged 50 to 75 years...

Cutaneous melanoma attributable to UVR exposure in Denmark and Germany.

European journal of cancer (Oxford, England : 1990)

Keim U, Gandini S, Amaral T, Katalinic A, Holleczek B, Flatz L, Leiter U, Whiteman D, Garbe C.
PMID: 34742161
Eur J Cancer. 2021 Dec;159:98-104. doi: 10.1016/j.ejca.2021.09.044. Epub 2021 Nov 03.

BACKGROUND: Increasing incidence rates of cutaneous melanoma (CM) observed during the last five decades in white populations are largely attributed to increased exposure to solar ultraviolet radiation (UVR), often expressed as population attributable fraction (PAF). Thus, many CMs could...

Prediction of clinical diagnosis of Alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic risk score and APOE status in a community-based cohort prospectively followed over 17 years.

Molecular psychiatry

Stocker H, Perna L, Weigl K, Möllers T, Schöttker B, Thomsen H, Holleczek B, Rujescu D, Brenner H.
PMID: 32404947
Mol Psychiatry. 2021 Oct;26(10):5812-5822. doi: 10.1038/s41380-020-0764-y. Epub 2020 May 13.

The strongest genetic risk factor for Alzheimer's disease (AD) is the ε4 allele of Apolipoprotein E (APOE) and recent genome-wide association meta-analyses have confirmed additional associated genetic loci with smaller effects. The aim of this study was to investigate...

Socioeconomic deprivation and cancer survival in a metropolitan area: An analysis of cancer registry data from Hamburg, Germany.

The Lancet regional health. Europe

Jansen L, Erb C, Nennecke A, Finke I, Pritzkuleit R, Holleczek B, Brenner H.
PMID: 34557810
Lancet Reg Health Eur. 2021 Feb 26;4:100063. doi: 10.1016/j.lanepe.2021.100063. eCollection 2021 May.

BACKGROUND: Few studies have investigated socioeconomic inequalities within cities. Yet, such analyses are particularly important given the increasing international trend to urbanization. Here we investigated area-based socioeconomic inequalities in cancer survival in Hamburg, a port city in the North...

Comparative validation of three DNA methylation algorithms of ageing and a frailty index in relation to mortality: results from the ESTHER cohort study.

EBioMedicine

Li X, Zhang Y, Gào X, Holleczek B, Schöttker B, Brenner H.
PMID: 34808433
EBioMedicine. 2021 Nov 19;74:103686. doi: 10.1016/j.ebiom.2021.103686. Epub 2021 Nov 19.

BACKGROUND: Three DNA methylation (DNAm) based algorithms, DNAm PhenoAge acceleration (AgeAccelPheno), DNAm GrimAge acceleration (AgeAccelGrim), and mortality risk score (MRscore), based on methylation in 513, 1030, and 10 CpGs, respectively, were established to predict health outcomes and mortality. We...

Prediction of clinical diagnosis of Alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic risk score and APOE status in a community-based cohort prospectively followed over 17 years.

Molecular psychiatry

Stocker H, Perna L, Weigl K, Möllers T, Schöttker B, Thomsen H, Holleczek B, Rujescu D, Brenner H.
PMID: 32404947
Mol Psychiatry. 2020 May 13; doi: 10.1038/s41380-020-0764-y. Epub 2020 May 13.

The strongest genetic risk factor for Alzheimer's disease (AD) is the ε4 allele of Apolipoprotein E (APOE) and recent genome-wide association meta-analyses have confirmed additional associated genetic loci with smaller effects. The aim of this study was to investigate...

Divergent Patterns and Trends in Breast Cancer Incidence, Mortality and Survival Among Older Women in Germany and the United States.

Cancers

Jansen L, Holleczek B, Kraywinkel K, Weberpals J, Schröder CC, Eberle A, Emrich K, Kajüter H, Katalinic A, Kieschke J, Nennecke A, Sirri E, Heil J, Schneeweiss A, Brenner H.
PMID: 32858964
Cancers (Basel). 2020 Aug 26;12(9). doi: 10.3390/cancers12092419.

BACKGROUND: Breast cancer treatment has changed tremendously over the last decades. In addition, the use of mammography screening for early detection has increased strongly. To evaluate the impact of these developments, long-term trends in incidence, mortality, stage distribution and...

Comparative validation of three DNA methylation algorithms of ageing and a frailty index in relation to mortality: results from the ESTHER cohort study.

EBioMedicine

Li X, Zhang Y, Gào X, Holleczek B, Schöttker B, Brenner H.
PMID: 34808433
EBioMedicine. 2021 Nov 19;74:103686. doi: 10.1016/j.ebiom.2021.103686. Epub 2021 Nov 19.

BACKGROUND: Three DNA methylation (DNAm) based algorithms, DNAm PhenoAge acceleration (AgeAccelPheno), DNAm GrimAge acceleration (AgeAccelGrim), and mortality risk score (MRscore), based on methylation in 513, 1030, and 10 CpGs, respectively, were established to predict health outcomes and mortality. We...

Correction: Prediction of clinical diagnosis of Alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic risk score and APOE status in a community-based cohort prospectively followed over 17 years.

Molecular psychiatry

Stocker H, Perna L, Weigl K, Möllers T, Schöttker B, Thomsen H, Holleczek B, Rujescu D, Brenner H.
PMID: 34599279
Mol Psychiatry. 2021 Oct;26(10):5823. doi: 10.1038/s41380-021-01311-x.

No abstract available.

Distress mediates the relationship between cognitive appraisal of medical care and benefit finding/posttraumatic growth in long-term cancer survivors.

Cancer

Liu Z, Doege D, Thong MSY, Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Nennecke A, Waldmann A, Zeißig SR, Pritzkuleit R, Arndt V.
PMID: 34196976
Cancer. 2021 Oct 01;127(19):3680-3690. doi: 10.1002/cncr.33684. Epub 2021 Jul 01.

BACKGROUND: The objective of this study was to ascertain long-term cancer survivors' (LTCS') appraisal of medical care and how these perceptions may influence their health and well-being, including benefit finding (BF) and posttraumatic growth (PTG).METHODS: In total, 6952 LTCS...

Showing 1 to 12 of 60 entries