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OP0010. Optimizing time from diagnosis to delivery in preeclampsia based on the future health prospects of offspring.

Pregnancy hypertension

Lykke JA, Boomsma JJ, Hollegaard B.
PMID: 26105855
Pregnancy Hypertens. 2013 Apr;3(2):65. doi: 10.1016/j.preghy.2013.04.025. Epub 2013 Jun 06.

INTRODUCTION: Limited data exist on long-term health-consequences of maternal preeclampsia for offspring.OBJECTIVES: We investigated long-term offspring morbidity following preeclampsia and related these data to the time from diagnosis to delivery.METHODS: We performed a registry based retrospective cohort study in...

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Lykke JA, Boomsma JJ, Hollegaard B. OP0010. Optimizing time from diagnosis to delivery in preeclampsia based on the future health prospects of offspring. Pregnancy Hypertens. 2013;3(2):65doi: 10.1016/j.preghy.2013.04.025.
Lykke, J. A., Boomsma, J. J., & Hollegaard, B. (2013). OP0010. Optimizing time from diagnosis to delivery in preeclampsia based on the future health prospects of offspring. Pregnancy hypertension, 3(2), 65. https://doi.org/10.1016/j.preghy.2013.04.025
Lykke, Jacob Alexander, et al. "OP0010. Optimizing time from diagnosis to delivery in preeclampsia based on the future health prospects of offspring." Pregnancy hypertension vol. 3,2 (2013): 65. doi: https://doi.org/10.1016/j.preghy.2013.04.025
Lykke JA, Boomsma JJ, Hollegaard B. OP0010. Optimizing time from diagnosis to delivery in preeclampsia based on the future health prospects of offspring. Pregnancy Hypertens. 2013 Apr;3(2):65. doi: 10.1016/j.preghy.2013.04.025. Epub 2013 Jun 06. PMID: 26105855.
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DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD.

Frontiers in psychiatry

Nissen JB, Hansen CS, Starnawska A, Mattheisen M, Børglum AD, Buttenschøn HN, Hollegaard M.
PMID: 27047397
Front Psychiatry. 2016 Mar 18;7:35. doi: 10.3389/fpsyt.2016.00035. eCollection 2016.

Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder. Non-genetic factors and their interaction with genes have attracted increasing attention. Epigenetics is regarded an important interface between environmental signals and activation/repression of genomic responses. Epigenetic mechanisms have not previously been examined...

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Nissen JB, Hansen CS, Starnawska A, et al. DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD. Front Psychiatry. 2016;7:35doi: 10.3389/fpsyt.2016.00035.
Nissen, J. B., Hansen, C. S., Starnawska, A., Mattheisen, M., Børglum, A. D., Buttenschøn, H. N., & Hollegaard, M. (2016). DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD. Frontiers in psychiatry, 735. https://doi.org/10.3389/fpsyt.2016.00035
Nissen, Judith Becker, et al. "DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD." Frontiers in psychiatry vol. 7 (2016): 35. doi: https://doi.org/10.3389/fpsyt.2016.00035
Nissen JB, Hansen CS, Starnawska A, Mattheisen M, Børglum AD, Buttenschøn HN, Hollegaard M. DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with OCD. Front Psychiatry. 2016 Mar 18;7:35. doi: 10.3389/fpsyt.2016.00035. eCollection 2016. PMID: 27047397; PMCID: PMC4796012.
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RNA sequencing of archived neonatal dried blood spots.

Molecular genetics and metabolism reports

Bybjerg-Grauholm J, Hagen CM, Khoo SK, Johannesen ML, Hansen CS, Bækvad-Hansen M, Christiansen M, Hougaard DM, Hollegaard MV.
PMID: 28053876
Mol Genet Metab Rep. 2016 Dec 24;10:33-37. doi: 10.1016/j.ymgmr.2016.12.004. eCollection 2017 Mar.

Neonatal dried blood spots (DBS) are routinely collected on standard Guthrie cards for all-comprising national newborn screening programs for inborn errors of metabolism, hypothyroidism and other diseases. In Denmark, the Guthrie cards are stored at - 20 °C in...

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Bybjerg-Grauholm J, Hagen CM, Khoo SK, et al. RNA sequencing of archived neonatal dried blood spots. Mol Genet Metab Rep. 2016;10:33-37doi: 10.1016/j.ymgmr.2016.12.004.
Bybjerg-Grauholm, J., Hagen, C. M., Khoo, S. K., Johannesen, M. L., Hansen, C. S., Bækvad-Hansen, M., Christiansen, M., Hougaard, D. M., & Hollegaard, M. V. (2017). RNA sequencing of archived neonatal dried blood spots. Molecular genetics and metabolism reports, 1033-37. https://doi.org/10.1016/j.ymgmr.2016.12.004
Bybjerg-Grauholm, Jonas, et al. "RNA sequencing of archived neonatal dried blood spots." Molecular genetics and metabolism reports vol. 10 (2017): 33-37. doi: https://doi.org/10.1016/j.ymgmr.2016.12.004
Bybjerg-Grauholm J, Hagen CM, Khoo SK, Johannesen ML, Hansen CS, Bækvad-Hansen M, Christiansen M, Hougaard DM, Hollegaard MV. RNA sequencing of archived neonatal dried blood spots. Mol Genet Metab Rep. 2016 Dec 24;10:33-37. doi: 10.1016/j.ymgmr.2016.12.004. eCollection 2017 Mar. PMID: 28053876; PMCID: PMC5198792.
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Time from pre-eclampsia diagnosis to delivery affects future health prospects of children.

Evolution, medicine, and public health

Hollegaard B, Lykke JA, Boomsma JJ.
PMID: 28421136
Evol Med Public Health. 2017 Feb 08;2017(1):53-66. doi: 10.1093/emph/eox004. eCollection 2017.

No abstract available.

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Hollegaard B, Lykke JA, Boomsma JJ. Time from pre-eclampsia diagnosis to delivery affects future health prospects of children. Evol Med Public Health. 2017;2017(1):53-66doi: 10.1093/emph/eox004.
Hollegaard, B., Lykke, J. A., & Boomsma, J. J. (2017). Time from pre-eclampsia diagnosis to delivery affects future health prospects of children. Evolution, medicine, and public health, 2017(1), 53-66. https://doi.org/10.1093/emph/eox004
Hollegaard, Birgitte, et al. "Time from pre-eclampsia diagnosis to delivery affects future health prospects of children." Evolution, medicine, and public health vol. 2017,1 (2017): 53-66. doi: https://doi.org/10.1093/emph/eox004
Hollegaard B, Lykke JA, Boomsma JJ. Time from pre-eclampsia diagnosis to delivery affects future health prospects of children. Evol Med Public Health. 2017 Feb 08;2017(1):53-66. doi: 10.1093/emph/eox004. eCollection 2017. PMID: 28421136; PMCID: PMC5387983.
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Evaluation of whole genome amplified DNA to decrease material expenditure and increase quality.

Molecular genetics and metabolism reports

Bækvad-Hansen M, Bybjerg-Grauholm J, Poulsen JB, Hansen CS, Hougaard DM, Hollegaard MV.
PMID: 28487825
Mol Genet Metab Rep. 2017 Apr 25;11:36-45. doi: 10.1016/j.ymgmr.2017.04.002. eCollection 2017 Jun.

AIM: The overall aim of this study is to evaluate whole genome amplification of DNA extracted from dried blood spot samples. We wish to explore ways of optimizing the amplification process, while decreasing the amount of input material and...

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Bækvad-Hansen M, Bybjerg-Grauholm J, Poulsen JB, et al. Evaluation of whole genome amplified DNA to decrease material expenditure and increase quality. Mol Genet Metab Rep. 2017;11:36-45doi: 10.1016/j.ymgmr.2017.04.002.
Bækvad-Hansen, M., Bybjerg-Grauholm, J., Poulsen, J. B., Hansen, C. S., Hougaard, D. M., & Hollegaard, M. V. (2017). Evaluation of whole genome amplified DNA to decrease material expenditure and increase quality. Molecular genetics and metabolism reports, 1136-45. https://doi.org/10.1016/j.ymgmr.2017.04.002
Bækvad-Hansen, Marie, et al. "Evaluation of whole genome amplified DNA to decrease material expenditure and increase quality." Molecular genetics and metabolism reports vol. 11 (2017): 36-45. doi: https://doi.org/10.1016/j.ymgmr.2017.04.002
Bækvad-Hansen M, Bybjerg-Grauholm J, Poulsen JB, Hansen CS, Hougaard DM, Hollegaard MV. Evaluation of whole genome amplified DNA to decrease material expenditure and increase quality. Mol Genet Metab Rep. 2017 Apr 25;11:36-45. doi: 10.1016/j.ymgmr.2017.04.002. eCollection 2017 Jun. PMID: 28487825; PMCID: PMC5408502.
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Mannose-Binding Lectin Gene, MBL2, Polymorphisms Do Not Increase Susceptibility to Invasive Meningococcal Disease in a Population of Danish Children.

Open forum infectious diseases

Lundbo LF, Sørensen HT, Clausen LN, Hollegaard MV, Hougaard DM, Konradsen HB, Harboe ZB, Nørgaard M, Benfield T.
PMID: 26464842
Open Forum Infect Dis. 2015 Sep 01;2(4):ofv127. doi: 10.1093/ofid/ofv127. eCollection 2015 Dec.

Background.  Neisseria meningitidis is the cause of meningococcal bacteremia and meningitis, and nasopharyngeal colonization with this pathogen is common. The incidence of invasive disease is highest in infants, whereas adolescents more often are carriers. Altered regulation or dysfunction of...

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Lundbo LF, Sørensen HT, Clausen LN, et al. Mannose-Binding Lectin Gene, MBL2, Polymorphisms Do Not Increase Susceptibility to Invasive Meningococcal Disease in a Population of Danish Children. Open Forum Infect Dis. 2015;2(4):ofv127doi: 10.1093/ofid/ofv127.
Lundbo, L. F., Sørensen, H. T., Clausen, L. N., Hollegaard, M. V., Hougaard, D. M., Konradsen, H. B., Harboe, Z. B., Nørgaard, M., & Benfield, T. (2015). Mannose-Binding Lectin Gene, MBL2, Polymorphisms Do Not Increase Susceptibility to Invasive Meningococcal Disease in a Population of Danish Children. Open forum infectious diseases, 2(4), ofv127. https://doi.org/10.1093/ofid/ofv127
Lundbo, Lene F, et al. "Mannose-Binding Lectin Gene, MBL2, Polymorphisms Do Not Increase Susceptibility to Invasive Meningococcal Disease in a Population of Danish Children." Open forum infectious diseases vol. 2,4 (2015): ofv127. doi: https://doi.org/10.1093/ofid/ofv127
Lundbo LF, Sørensen HT, Clausen LN, Hollegaard MV, Hougaard DM, Konradsen HB, Harboe ZB, Nørgaard M, Benfield T. Mannose-Binding Lectin Gene, MBL2, Polymorphisms Do Not Increase Susceptibility to Invasive Meningococcal Disease in a Population of Danish Children. Open Forum Infect Dis. 2015 Sep 01;2(4):ofv127. doi: 10.1093/ofid/ofv127. eCollection 2015 Dec. PMID: 26464842; PMCID: PMC4602025.
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