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Showing 1 to 7 of 7 entries
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[What do physicians expect from nurses in the future society?].

Sygeplejersken

Holm-Nielsen P.
PMID: 4490162
Sygeplejersken. 1973 May 31;73(18):4-7.

No abstract available.

A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis.

Biochemistry and biophysics reports

Leeming DJ, Willumsen N, Sand JMB, Holm Nielsen S, Dasgupta B, Brodmerkel C, Curran M, Bager CL, Karsdal MA.
PMID: 30555938
Biochem Biophys Rep. 2018 Nov 30;17:38-43. doi: 10.1016/j.bbrep.2018.11.002. eCollection 2019 Mar.

OBJECTIVES: Lysyl oxidase like 2 (LOXL2) is associated with poor prognosis in idiopathic pulmonary disease (IPF) and cancer. We developed an Enzyme-linked immunosorbent assay (ELISA) targeting the LOXL2 neo-epitope generated through the release of the signal peptide during LOXL2...

Considerations for understanding protein measurements: Identification of formation, degradation and more pathological relevant epitopes.

Clinical biochemistry

Karsdal MA, Genovese F, Rasmussen DGK, Bay-Jensen AC, Mortensen JH, Holm Nielsen S, Willumsen N, Jensen C, Manon-Jensen T, Jennings L, Reese-Petersen AL, Henriksen K, Sand JM, Bager C, Leeming DJ.
PMID: 34453894
Clin Biochem. 2021 Nov;97:11-24. doi: 10.1016/j.clinbiochem.2021.08.007. Epub 2021 Aug 26.

OBJECTIVES: There is a need for precision medicine and an unspoken promise of an optimal approach for identification of the right patients for value-based medicine based on big data. However, there may be a misconception that measurement of proteins...

Cross-Linked Multimeric Pro-Peptides of Type III Collagen (PC3X) in Hepatocellular Carcinoma - A Biomarker That Provides Additional Prognostic Value in AFP Positive Patients.

Journal of hepatocellular carcinoma

Jensen C, Holm Nielsen S, Eslam M, Genovese F, Nielsen MJ, Vongsuvanh R, Uchila R, van der Poorten D, George J, Karsdal MA, Leeming DJ, Willumsen N.
PMID: 33204663
J Hepatocell Carcinoma. 2020 Nov 09;7:301-313. doi: 10.2147/JHC.S275008. eCollection 2020.

PURPOSE: Non-invasive biomarkers for diagnosing and prognosing hepatocellular carcinoma (HCC) are urgently needed. Cirrhosis is present in 80-90% of HCC patients. Cirrhosis is characterized by deposition and cross-linking of collagens that have crucial roles in HCC initiation and progression....

Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone.

Pulmonary circulation

Andersen S, Birkmose Axelsen J, Ringgaard S, Randel Nyengaard J, Holm Nielsen S, Genovese F, Asser Karsdal M, Adler Hyldebrandt J, Brandt Sørensen C, de Man FS, Jan Bogaard H, Erik Nielsen-Kudsk J, Andersen A.
PMID: 30997866
Pulm Circ. 2019 Apr-Jun;9(2):2045894019848659. doi: 10.1177/2045894019848659.

Cardiac fibrosis contributes to the development of heart failure in pulmonary hypertension. We aimed to assess the development of fibrosis and the effects of treatment with the anti-fibrotic agent pirfenidone in pressure overload induced right ventricular (RV) failure. Wistar...

Electricity consumption data of a student residence in Southern Africa.

Data in brief

Masebinu SO, Holm-Nielsen JB, Mbohwa C, Padmanaban S, Nwulu N.
PMID: 32904363
Data Brief. 2020 Aug 08;32:106150. doi: 10.1016/j.dib.2020.106150. eCollection 2020 Oct.

The time-series dataset presented in this article was captured using a real-time energy monitoring device from a distribution panel of a student residence in Johannesburg, South Africa. The data was captured from April 2016 to January 2018. The data...

Serological Assessment of Activated Fibroblasts by alpha-Smooth Muscle Actin (α-SMA): A Noninvasive Biomarker of Activated Fibroblasts in Lung Disorders.

Translational oncology

Holm Nielsen S, Willumsen N, Leeming DJ, Daniels SJ, Brix S, Karsdal MA, Genovese F, Nielsen MJ.
PMID: 30504086
Transl Oncol. 2019 Feb;12(2):368-374. doi: 10.1016/j.tranon.2018.11.004. Epub 2018 Nov 30.

OBJECTIVES: Remodeling of the extracellular matrix (ECM) is a key event in different lung disorders, such as fibrosis and cancer. The most common cell type in the connective tissue is fibroblasts, which transdifferentiate into myofibroblasts upon activation. All myofibroblasts...

Showing 1 to 7 of 7 entries