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Showing 1 to 12 of 27 entries
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A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics.

CBE life sciences education

Lopatto D, Hauser C, Jones CJ, Paetkau D, Chandrasekaran V, Dunbar D, MacKinnon C, Stamm J, Alvarez C, Barnard D, Bedard JE, Bednarski AE, Bhalla S, Braverman JM, Burg M, Chung HM, DeJong RJ, DiAngelo JR, Du C, Eckdahl TT, Emerson J, Frary A, Frohlich D, Goodman AL, Gosser Y, Govind S, Haberman A, Hark AT, Hoogewerf A, Johnson D, Kadlec L, Kaehler M, Key SC, Kokan NP, Kopp OR, Kuleck GA, Lopilato J, Martinez-Cruzado JC, McNeil G, Mel S, Nagengast A, Overvoorde PJ, Parrish S, Preuss ML, Reed LD, Regisford EG, Revie D, Robic S, Roecklien-Canfield JA, Rosenwald AG, Rubin MR, Saville K, Schroeder S, Sharif KA, Shaw M, Skuse G, Smith CD, Smith M, Smith ST, Spana EP, Spratt M, Sreenivasan A, Thompson JS, Wawersik M, Wolyniak MJ, Youngblom J, Zhou L, Buhler J, Mardis E, Leung W, Shaffer CD, Threlfall J, Elgin SC.
PMID: 25452493
CBE Life Sci Educ. 2014;13(4):711-23. doi: 10.1187/cbe.13-10-0200.

In their 2012 report, the President's Council of Advisors on Science and Technology advocated "replacing standard science laboratory courses with discovery-based research courses"-a challenging proposition that presents practical and pedagogical difficulties. In this paper, we describe our collective experiences...

Block copolymer micelles as switchable templates for nanofabrication.

Langmuir : the ACS journal of surfaces and colloids

Krishnamoorthy S, Pugin R, Brugger J, Heinzelmann H, Hoogerwerf AC, Hinderling C.
PMID: 16584207
Langmuir. 2006 Apr 11;22(8):3450-2. doi: 10.1021/la052299a.

Block copolymer inverse micelles from polystyrene-block-poly-2-vinylpyridine (PS-b-P2VP) deposited as monolayer films onto surfaces show responsive behavior and are reversibly switchable between two states of different topography and surface chemistry. The as-coated films are in the form of arrays of...

Association Between Prehospital Tranexamic Acid Administration and Outcomes of Severe Traumatic Brain Injury.

JAMA neurology

Bossers SM, Loer SA, Bloemers FW, Den Hartog D, Van Lieshout EMM, Hoogerwerf N, van der Naalt J, Absalom AR, Peerdeman SM, Schwarte LA, Boer C, Schober P.
PMID: 33284310
JAMA Neurol. 2021 Mar 01;78(3):338-345. doi: 10.1001/jamaneurol.2020.4596.

IMPORTANCE: The development and expansion of intracranial hematoma are associated with adverse outcomes. Use of tranexamic acid might limit intracranial hematoma formation, but its association with outcomes of severe traumatic brain injury (TBI) is unclear.OBJECTIVE: To assess whether prehospital...

Rural youth's exposure to firearm violence and their attitudes regarding firearm safety measures.

Injury epidemiology

Jennissen CA, King RP, Wetjen KM, Denning GM, Wymore CC, Stange NR, Hoogerwerf PJ, Liao J, Wood KE.
PMID: 34517921
Inj Epidemiol. 2021 Sep 13;8:29. doi: 10.1186/s40621-021-00317-x.

BACKGROUND: In the wake of an epidemic in firearm-related deaths and injuries, youth have become leading voices of concern. This study's objective was to investigate rural youth's personal experiences with firearm-related violence, and their attitudes towards firearms and gun...

Molecular cloning of the rat proteinase-activated receptor 4 (PAR4).

BMC molecular biology

Hoogerwerf WA, Hellmich HL, Micci MA, Winston JH, Zou L, Pasricha PJ.
PMID: 11886595
BMC Mol Biol. 2002;3:2. doi: 10.1186/1471-2199-3-2. Epub 2002 Feb 18.

BACKGROUND: The proteinase-activated receptor 4 (PAR4) is a G-protein-coupled receptor activated by proteases such as thrombin and trypsin. Although activation of PAR4 has been shown to modulate rat gastrointestinal motility, the rat PAR4 sequence was unknown until now. This...

A Randomized Controlled Trial to Investigate Safety and Variability of Egg Excretion After Repeated Controlled Human Hookworm Infection.

The Journal of infectious diseases

Hoogerwerf MA, Koopman JPR, Janse JJ, Langenberg MCC, van Schuijlenburg R, Kruize YCM, Brienen EAT, Manurung MD, Verbeek-Menken P, van der Beek MT, Westra IM, Meij P, Visser LG, van Lieshout L, de Vlas SJ, Yazdanbakhsh M, Coffeng LE, Roestenberg M.
PMID: 32645714
J Infect Dis. 2021 Mar 03;223(5):905-913. doi: 10.1093/infdis/jiaa414.

BACKGROUND: Controlled human hookworm infections could significantly contribute to the development of a hookworm vaccine. However, current models are hampered by low and unstable egg output, reducing generalizability and increasing sample sizes. This study aims to investigate the safety,...

Parental attitudes and family helmet use for all-terrain vehicles and bicycles.

Injury epidemiology

Wymore C, Denning G, Hoogerwerf P, Wetjen K, Jennissen C.
PMID: 32532340
Inj Epidemiol. 2020 Jun 12;7:23. doi: 10.1186/s40621-020-00253-2.

BACKGROUND: Helmets prevent head trauma in both all-terrain vehicle (ATV) and bicycle crashes. This pilot study's objective was to compare family helmet use and participant attitudes regarding helmets for ATVs versus bicycles.METHODS: A convenience sampling of adults attending a...

Association Between Prehospital Tranexamic Acid Administration and Outcomes of Severe Traumatic Brain Injury.

JAMA neurology

Bossers SM, Loer SA, Bloemers FW, Den Hartog D, Van Lieshout EMM, Hoogerwerf N, van der Naalt J, Absalom AR, Peerdeman SM, Schwarte LA, Boer C, Schober P.
PMID: 33284310
JAMA Neurol. 2021 Mar 01;78(3):338-345. doi: 10.1001/jamaneurol.2020.4596.

IMPORTANCE: The development and expansion of intracranial hematoma are associated with adverse outcomes. Use of tranexamic acid might limit intracranial hematoma formation, but its association with outcomes of severe traumatic brain injury (TBI) is unclear.OBJECTIVE: To assess whether prehospital...

Establishing a controlled hookworm human infection (CHHI) model for Africa: A report from the stakeholders meeting held in Lambaréné, Gabon, November 10-11, 2019.

Archives of public health = Archives belges de sante publique

Alabi A, Hussain M, Hoogerwerf MA, Mengome CN, Egesa M, Driciru E, Wammes LJ, Kruize YCM, Sartono E, Adegnika AA, Kremsner PG, Yazdanbakhsh M, Agnandji ST.
PMID: 34225793
Arch Public Health. 2021 Jul 05;79(1):120. doi: 10.1186/s13690-021-00650-z.

BACKGROUND: Hookworm is a major contributor to worldwide disease burden with over 230 million people infected. It has been identified as one of the Neglected Tropical Diseases that can be controlled and even eliminated through mass drug administration and...

Appropriate empirical antibiotic use in the emergency department: full compliance matters!.

JAC-antimicrobial resistance

Berrevoets MAH, Ten Oever J, Hoogerwerf J, Kullberg BJ, Atsma F, Hulscher ME, Schouten JA.
PMID: 34222935
JAC Antimicrob Resist. 2019 Nov 13;1(3):dlz061. doi: 10.1093/jacamr/dlz061. eCollection 2019 Dec.

BACKGROUND: Little is known about determinants of appropriate antibiotic use in the emergency department (ED). We measured appropriateness of antibiotic use for seven quality indicators (QIs) and studied patient-related factors that determine their variation.PATIENTS AND METHODS: A retrospective analysis...

Comparison of SARS-CoV-2 neutralizing antibody testing of convalescent plasma donations in the Netherlands and England: A pilot study.

Health science reports

Harvala H, Gopal R, Patel M, Zambon M, Roberts D, Lamikanra A, Ploeg R, Hoogerwerf M, Zaaijer H, Hogema B, Reusken C, van der Schoot E, Reimerink J.
PMID: 34888419
Health Sci Rep. 2021 Dec 02;4(4):e439. doi: 10.1002/hsr2.439. eCollection 2021 Dec.

No abstract available.

ABCDE of prehospital ultrasonography: a narrative review.

Critical ultrasound journal

Ketelaars R, Reijnders G, van Geffen GJ, Scheffer GJ, Hoogerwerf N.
PMID: 30088160
Crit Ultrasound J. 2018 Aug 08;10(1):17. doi: 10.1186/s13089-018-0099-y.

Prehospital point-of-care ultrasound used by nonradiologists in emergency medicine is gaining ground. It is feasible on-scene and during aeromedical transport and allows health-care professionals to detect or rule out potential harmful conditions. Consequently, it impacts decision-making in prioritizing care,...

Showing 1 to 12 of 27 entries