Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 11 of 11 entries
Sorted by: Best Match Show Resources per page
Threat Interpretation Bias in Children With Obsessive-Compulsive Disorder: Examining Maternal Influences.

Journal of cognitive psychotherapy

Farrell LJ, Hourigan D, Waters AM, Harrington MR.
PMID: 32755950
J Cogn Psychother. 2015;29(3):230-252. doi: 10.1891/0889-8391.29.3.230. Epub 2015 Jan 01.

Obsessive-compulsive disorder (OCD) in children is a chronic and debilitating disorder. Cognitive theories propose that threat biases may play a role in the development and maintenance of various anxiety disorders, including OCD. Although there is a small body of...

Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects.

Brain : a journal of neurology

Niestroj LM, Perez-Palma E, Howrigan DP, Zhou Y, Cheng F, Saarentaus E, Nürnberg P, Stevelink R, Daly MJ, Palotie A, Lal D.
PMID: 32568404
Brain. 2020 Jul 01;143(7):2106-2118. doi: 10.1093/brain/awaa171.

Cytogenic testing is routinely applied in most neurological centres for severe paediatric epilepsies. However, which characteristics of copy number variants (CNVs) confer most epilepsy risk and which epilepsy subtypes carry the most CNV burden, have not been explored on...

Inhibition of the endosomal recycling pathway downregulates HER2 activation and overcomes resistance to tyrosine kinase inhibitors in HER2-positive breast cancer.

Cancer letters

Mishra A, Hourigan D, Lindsay AJ.
PMID: 35007696
Cancer Lett. 2022 Jan 07;529:153-167. doi: 10.1016/j.canlet.2022.01.003. Epub 2022 Jan 07.

The development of HER2-targeted therapies has led to a dramatic improvement in outcomes for breast cancer patients. However, nearly all patients with metastatic HER2-positive breast cancer will eventually progress on these therapies due to innate or acquired resistance. Recent...

The effects of team-training in intensive care medicine: A narrative review.

Journal of critical care

Low XM, Horrigan D, Brewster DJ.
PMID: 30268058
J Crit Care. 2018 Dec;48:283-289. doi: 10.1016/j.jcrc.2018.09.015. Epub 2018 Sep 20.

PURPOSE: Research into team-training within healthcare is growing exponentially. We aim to evaluate the effects of team-training within intensive care medicine (ICM) through a review of the literature and a narrative synthesis of the results.MATERIALS AND METHODS: A search...

Experimental measurements of sidebranching in thermal dendrites under terrestrial-gravity and microgravity conditions.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics

Corrigan DP, Koss MB, LaCombe JC, de Jager KD, Tennenhouse LA, Glicksman ME.
PMID: 11970665
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1999 Dec;60(6):7217-23. doi: 10.1103/physreve.60.7217.

We perform sidebranch measurements on pure succinonitrile dendrites grown in both microgravity and terrestrial-gravity conditions for a set of supercoolings within the range 0.1-1.0 K. Two distinct types of sidebranch regions, uniform and coarsening, exist, and are characterized by...

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population.

Nature neuroscience

Ganna A, Genovese G, Howrigan DP, Byrnes A, Kurki M, Zekavat SM, Whelan CW, Kals M, Nivard MG, Bloemendal A, Bloom JM, Goldstein JI, Poterba T, Seed C, Handsaker RE, Natarajan P, Mägi R, Gage D, Robinson EB, Metspalu A, Salomaa V, Suvisaari J, Purcell SM, Sklar P, Kathiresan S, Daly MJ, McCarroll SA, Sullivan PF, Palotie A, Esko T, Hultman C, Neale BM.
PMID: 27694993
Nat Neurosci. 2016 Dec;19(12):1563-1565. doi: 10.1038/nn.4404. Epub 2016 Oct 03.

Disruptive, damaging ultra-rare variants in highly constrained genes are enriched in individuals with neurodevelopmental disorders. In the general population, this class of variants was associated with a decrease in years of education (YOE). This effect was stronger among highly...

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Molecular psychiatry

Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Cantwell L, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples LA, Dartigues JF, Debette S, Deleuze JF, Fulton L, Gabriel SB, Genin E, Gibbs RA, Goate A, Grenier-Boley B, Gupta N, Haines JL, Havulinna AS, Helisalmi S, Hiltunen M, Howrigan DP, Ikram MA, Kaprio J, Konrad J, Kuzma A, Lander ES, Lathrop M, Lehtimäki T, Lin H, Mattila K, Mayeux R, Muzny DM, Nasser W, Neale B, Nho K, Nicolas G, Patel D, Pericak-Vance MA, Perola M, Psaty BM, Quenez O, Rajabli F, Redon R, Reitz C, Remes AM, Salomaa V, Sarnowski C, Schmidt H, Schmidt M, Schmidt R, Soininen H, Thornton TA, Tosto G, Tzourio C, van der Lee SJ, van Duijn CM, Valladares O, Vardarajan B, Wang LS, Wang W, Wijsman E, Wilson RK, Witten D, Worley KC, Zhang X, Bellenguez C, Lambert JC, Kurki MI, Palotie A, Daly M, Boerwinkle E, Lunetta KL, Destefano AL, Dupuis J, Martin ER, Schellenberg GD, Seshadri S, Naj AC, Fornage M, Farrer LA.
PMID: 31636380
Mol Psychiatry. 2020 Aug;25(8):1901-1903. doi: 10.1038/s41380-019-0529-7.

A correction to this paper has been published and can be accessed via a link at the top of the paper.

Inhibition of the endosomal recycling pathway downregulates HER2 activation and overcomes resistance to tyrosine kinase inhibitors in HER2-positive breast cancer.

Cancer letters

Mishra A, Hourigan D, Lindsay AJ.
PMID: 35007696
Cancer Lett. 2022 Jan 07; doi: 10.1016/j.canlet.2022.01.003. Epub 2022 Jan 07.

The development of HER2-targeted therapies has led to a dramatic improvement in outcomes for breast cancer patients. However, nearly all patients with metastatic HER2-positive breast cancer will eventually progress on these therapies due to innate or acquired resistance. Recent...

Publisher Correction: Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein.

Nature neuroscience

Farhan SMK, Howrigan DP, Abbott LE, Klim JR, Topp SD, Byrnes AE, Churchhouse C, Phatnani H, Smith BN, Rampersaud E, Wu G, Wuu J, Shatunov A, Iacoangeli A, Khleifat AA, Mordes DA, Ghosh S, Eggan K, Rademakers R, McCauley JL, Schüle R, Züchner S, Benatar M, Taylor JP, Nalls M, Gotkine M, Shaw PJ, Morrison KE, Al-Chalabi A, Traynor B, Shaw CE, Goldstein DB, Harms MB, Daly MJ, Neale BM.
PMID: 31857710
Nat Neurosci. 2020 Feb;23(2):295. doi: 10.1038/s41593-019-0570-5.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Inhibition of the endosomal recycling pathway downregulates HER2 activation and overcomes resistance to tyrosine kinase inhibitors in HER2-positive breast cancer.

Cancer letters

Mishra A, Hourigan D, Lindsay AJ.
PMID: 35007696
Cancer Lett. 2022 Jan 07;529:153-167. doi: 10.1016/j.canlet.2022.01.003. Epub 2022 Jan 07.

The development of HER2-targeted therapies has led to a dramatic improvement in outcomes for breast cancer patients. However, nearly all patients with metastatic HER2-positive breast cancer will eventually progress on these therapies due to innate or acquired resistance. Recent...

Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects.

Nature communications

Regier AA, Farjoun Y, Larson DE, Krasheninina O, Kang HM, Howrigan DP, Chen BJ, Kher M, Banks E, Ames DC, English AC, Li H, Xing J, Zhang Y, Matise T, Abecasis GR, Salerno W, Zody MC, Neale BM, Hall IM.
PMID: 30279509
Nat Commun. 2018 Oct 02;9(1):4038. doi: 10.1038/s41467-018-06159-4.

Hundreds of thousands of human whole genome sequencing (WGS) datasets will be generated over the next few years. These data are more valuable in aggregate: joint analysis of genomes from many sources increases sample size and statistical power. A...

Showing 1 to 11 of 11 entries