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Showing 1 to 12 of 27 entries
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Disseminated histoplasmosis associated with acquired hemophagocytic lymphohistiocytosis.

Clinical case reports

Rajput A, Bence-Bruckler I, Huebsch L, Jessamine P, Toye B, Padmore R.
PMID: 25838912
Clin Case Rep. 2015 Mar;3(3):195-6. doi: 10.1002/ccr3.179. Epub 2014 Dec 04.

Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening clinical syndrome caused by uncontrolled activation of lymphocytes and histiocytes resulting in high levels of cytokines. Acquired HLH occurs in autoimmune, inflammatory, infectious, and immunosuppressive disorders. Prompt identification and treatment of an...

Outcomes in a nurse-led peripherally inserted central catheter program: a retrospective cohort study.

CMAJ open

McDiarmid S, Scrivens N, Carrier M, Sabri E, Toye B, Huebsch L, Fergusson D.
PMID: 28676535
CMAJ Open. 2017 Jun 30;5(3):E535-E539. doi: 10.9778/cmajo.20170010.

BACKGROUND: Peripherally inserted central catheters (PICCs) provide enormous benefit to patients. However, recent publications have highlighted relatively high PICC-associated complication rates. We report on patient and device outcomes from a nurse-led program.METHODS: We performed a retrospective analysis of a...

Copper-Free Azide-Alkyne Cycloaddition for Peptide Modification of Alginate Hydrogels.

ACS applied bio materials

Jain E, Neal S, Graf H, Tan X, Balasubramaniam R, Huebsch N.
PMID: 35014476
ACS Appl Bio Mater. 2021 Feb 15;4(2):1229-1237. doi: 10.1021/acsabm.0c00976. Epub 2021 Feb 01.

Alginate, a biocompatible polymer naturally derived from algae, is widely used as a synthetic analogue of the extracellular matrix in tissue engineering. Integrin-binding peptide motifs, including RGD, a derivative of fibronectin, are typically grafted to the alginate polymer through...

Integrated Isogenic Human Induced Pluripotent Stem Cell-Based Liver and Heart Microphysiological Systems Predict Unsafe Drug-Drug Interaction.

Frontiers in pharmacology

Lee-Montiel FT, Laemmle A, Charwat V, Dumont L, Lee CS, Huebsch N, Okochi H, Hancock MJ, Siemons B, Boggess SC, Goswami I, Miller EW, Willenbring H, Healy KE.
PMID: 34025426
Front Pharmacol. 2021 May 07;12:667010. doi: 10.3389/fphar.2021.667010. eCollection 2021.

Three-dimensional (3D) microphysiological systems (MPSs) mimicking human organ function

Does Up-front Autologous Stem-Cell Transplantation at First Relapse Improve Outcome in Transplant-Eligible Follicular Lymphoma Patients Whose Disease Relapses Within 24 Months?.

Clinical lymphoma, myeloma & leukemia

Yahya A, Radhwi O, Sobh M, Huebsch L, MacDonald D.
PMID: 33558203
Clin Lymphoma Myeloma Leuk. 2021 Apr;21(4):e423-e427. doi: 10.1016/j.clml.2020.12.011. Epub 2021 Feb 06.

BACKGROUND: In Canadian adults, follicular lymphoma (FL) is the most common subtype of non-Hodgkin lymphomas. Approximately 20% of patients with FL experience progression of disease within 2 years of first-line chemoimmunotherapy. Those patients have an expected overall survival of...

Autologous Hematopoietic Stem Cell Transplantation for Chronic Inflammatory Demyelinating Polyradiculoneuropathy.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

Masson-Roy J, Breiner A, Warman-Chardon J, Pringle CE, Allan D, Bredeson C, Huebsch L, Kekre N, Kennah ML, Martin L, McDiarmid S, Altouri S, Atkins H, Bourque PR.
PMID: 33631093
Can J Neurol Sci. 2021 Feb 26;1-7. doi: 10.1017/cjn.2021.30. Epub 2021 Feb 26.

BACKGROUND: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) refractory to conventional therapy can lead to marked disability and represents a therapeutic challenge.OBJECTIVE: To report five cases of treatment-refractory disabling CIDP treated with autologous hematopoietic stem cell transplantation (AHSCT).METHODS: This was a...

THE BOWL THEOREM AND A MODEL NONDEGENERATE FUNCTION.

Proceedings of the National Academy of Sciences of the United States of America

Huebsch W, Morse M.
PMID: 16591134
Proc Natl Acad Sci U S A. 1964 Jan;51(1):49-51. doi: 10.1073/pnas.51.1.49.

No abstract available.

THE DEPENDENCE OF THE SCHOENFLIES EXTENSION ON AN ACCESSORY PARAMETER (THE TOPOLOGICAL CASE).

Proceedings of the National Academy of Sciences of the United States of America

Huebsch W, Morse M.
PMID: 16578553
Proc Natl Acad Sci U S A. 1963 Dec;50(6):1036-7. doi: 10.1073/pnas.50.6.1036.

No abstract available.

Interplay of Genotype and Substrate Stiffness in Driving the Hypertrophic Cardiomyopathy Phenotype in iPSC-Micro-Heart Muscle Arrays.

Cellular and molecular bioengineering

Guo J, Jiang H, Oguntuyo K, Rios B, Boodram Z, Huebsch N.
PMID: 34777601
Cell Mol Bioeng. 2021 Jun 25;14(5):409-425. doi: 10.1007/s12195-021-00684-x. eCollection 2021 Oct.

INTRODUCTION: In clinical and animal studies, Hypertrophic Cardiomyopathy (HCM) shares many similarities with non-inherited cardiac hypertrophy induced by pressure overload (hypertension). This suggests a potential role for mechanical stress in priming tissues with mutation-induced changes in the sarcomere to...

Erratum to "Filgrastim-Stimulated Bone Marrow Compared with Filgrastim-Mobilized Peripheral Blood in Myeloablative Sibling Allografting for Patients with Hematologic Malignancies: A Randomized Canadian Blood and Marrow Transplant Group Study" [Biol Blood Marrow Transplant 2016;22:1410-1415].

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation

Couban S, Aljurf M, Lachance S, Walker I, Toze C, Rubinger M, Lipton JH, Lee SJ, Szer J, Doocey R, Lewis ID, Huebsch L, Howson-Jan K, Lalancette M, Almohareb F, Chaudhri N, Ivison S, Broady R, Levings M, Fairclough D, Devins G, Szwajcer D, Foley R, Smith C, Panzarella T, Kerr H, Kariminia A, Schultz KR.
PMID: 27789277
Biol Blood Marrow Transplant. 2017 Mar;23(3):534. doi: 10.1016/j.bbmt.2016.09.021. Epub 2016 Oct 24.

No abstract available.

Pulsus Alternans in Cardiogenic Shock Recapitulated in Single Cell Fluorescence Imaging of a Patient's Cardiomyocyte.

Circulation. Heart failure

Moreno JD, Bhagavan D, Li A, Gerstner NC, Miller EW, Huebsch N, Cresci S, Silva JR.
PMID: 34886677
Circ Heart Fail. 2021 Dec 10;CIRCHEARTFAILURE121008855. doi: 10.1161/CIRCHEARTFAILURE.121.008855. Epub 2021 Dec 10.

No abstract available.

Autologous Hematopoietic Stem Cell Transplantation for Liver Transplant Recipients With Recurrent Primary Sclerosing Cholangitis: A Pilot Study.

Transplantation

Chruscinski A, Juvet S, Moshkelgosha S, Renner E, Lilly L, Selzner N, Bredeson C, Grant D, Adeyi O, Fischer S, Demetris AJ, Zhang J, Epstein M, Macarthur M, Clement AM, Khalili K, Allan D, Altouri S, Bence-Bruckler I, Cattral M, Fulcher J, Galvin Z, Ghanekar A, Greig P, Huebsch L, Humar A, Kew A, Kekre N, Kim TK, McDiarmid S, Martin L, McGilvray I, Sabloff M, Sapisochin G, Selzner M, Smith R, Tinckham K, Yi TJ, Levy G, Atkins H.
PMID: 34049362
Transplantation. 2021 May 25; doi: 10.1097/TP.0000000000003829. Epub 2021 May 25.

BACKGROUND: Primary sclerosing cholangitis (PSC) is an indication for liver transplantation, but recurrence after liver transplantation is associated with poor outcomes often requiring repeat transplantation. We investigated whether autologous hematopoietic stem cell transplantation (aHSCT) could be used to stop...

Showing 1 to 12 of 27 entries