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Impact of the number of repeated inhalations and patient characteristics on the residual amount of inhaled laninamivir octanoate hydrate dry powder in pediatric patients with influenza.

Journal of pharmaceutical health care and sciences

Murasaka T, Ikemura K, Enokiya T, Muraki Y, Ikemura M, Terada K, Iwamoto T, Okuda M.
PMID: 29152321
J Pharm Health Care Sci. 2017 Nov 08;3:26. doi: 10.1186/s40780-017-0094-7. eCollection 2017.

BACKGROUND: A dry powder inhaled formulation is used for the anti-influenza drug laninamivir octanoate hydrate (laninamivir). Although two successive inhalations (puffs) are recommended to minimize residual amounts of active ingredients, previous reports suggest that pediatric patients with low peak...

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Murasaka T, Ikemura K, Enokiya T, et al. Impact of the number of repeated inhalations and patient characteristics on the residual amount of inhaled laninamivir octanoate hydrate dry powder in pediatric patients with influenza. J Pharm Health Care Sci. 2017;3:26doi: 10.1186/s40780-017-0094-7.
Murasaka, T., Ikemura, K., Enokiya, T., Muraki, Y., Ikemura, M., Terada, K., Iwamoto, T., & Okuda, M. (2017). Impact of the number of repeated inhalations and patient characteristics on the residual amount of inhaled laninamivir octanoate hydrate dry powder in pediatric patients with influenza. Journal of pharmaceutical health care and sciences, 326. https://doi.org/10.1186/s40780-017-0094-7
Murasaka, Toshiki, et al. "Impact of the number of repeated inhalations and patient characteristics on the residual amount of inhaled laninamivir octanoate hydrate dry powder in pediatric patients with influenza." Journal of pharmaceutical health care and sciences vol. 3 (2017): 26. doi: https://doi.org/10.1186/s40780-017-0094-7
Murasaka T, Ikemura K, Enokiya T, Muraki Y, Ikemura M, Terada K, Iwamoto T, Okuda M. Impact of the number of repeated inhalations and patient characteristics on the residual amount of inhaled laninamivir octanoate hydrate dry powder in pediatric patients with influenza. J Pharm Health Care Sci. 2017 Nov 08;3:26. doi: 10.1186/s40780-017-0094-7. eCollection 2017. PMID: 29152321; PMCID: PMC5678805.
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A Case of Hyperammonemia Associated with High Dihydropyrimidine Dehydrogenase Activity.

Case reports in oncological medicine

Nagaharu K, Ikemura K, Yamashita Y, Oda H, Ishihara M, Sugawara Y, Tamaru S, Mizuno T, Katayama N.
PMID: 27195162
Case Rep Oncol Med. 2016;2016:7510901. doi: 10.1155/2016/7510901. Epub 2016 Apr 19.

Over the past decades, 5-Fluorouracil (5-FU) has been widely used to treat several types of carcinoma, including esophageal squamous cell carcinoma. In addition to its common side effects, including diarrhea, mucositis, neutropenia, and anemia, 5-FU treatment has also been...

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Nagaharu K, Ikemura K, Yamashita Y, et al. A Case of Hyperammonemia Associated with High Dihydropyrimidine Dehydrogenase Activity. Case Rep Oncol Med. 2016;2016:7510901doi: 10.1155/2016/7510901.
Nagaharu, K., Ikemura, K., Yamashita, Y., Oda, H., Ishihara, M., Sugawara, Y., Tamaru, S., Mizuno, T., & Katayama, N. (2016). A Case of Hyperammonemia Associated with High Dihydropyrimidine Dehydrogenase Activity. Case reports in oncological medicine, 20167510901. https://doi.org/10.1155/2016/7510901
Nagaharu, Keiki, et al. "A Case of Hyperammonemia Associated with High Dihydropyrimidine Dehydrogenase Activity." Case reports in oncological medicine vol. 2016 (2016): 7510901. doi: https://doi.org/10.1155/2016/7510901
Nagaharu K, Ikemura K, Yamashita Y, Oda H, Ishihara M, Sugawara Y, Tamaru S, Mizuno T, Katayama N. A Case of Hyperammonemia Associated with High Dihydropyrimidine Dehydrogenase Activity. Case Rep Oncol Med. 2016;2016:7510901. doi: 10.1155/2016/7510901. Epub 2016 Apr 19. PMID: 27195162; PMCID: PMC4853945.
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A (90)Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy.

EJNMMI research

Fujiwara K, Koyama K, Suga K, Ikemura M, Saito Y, Hino A, Iwanari H, Kusano-Arai O, Mitsui K, Kasahara H, Fukayama M, Kodama T, Hamakubo T, Momose T.
PMID: 25006547
EJNMMI Res. 2014 Jun 01;4:29. doi: 10.1186/s13550-014-0029-3. eCollection 2014.

BACKGROUND: ROBO1 is a membrane protein that functions in axon guidance. ROBO1 contributes to tumour metastasis and angiogenesis and may have potential as a target protein of immunotherapy because ROBO1 is specifically expressed at high levels in hepatocellular carcinoma....

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Fujiwara K, Koyama K, Suga K, et al. A (90)Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy. EJNMMI Res. 2014;4:29doi: 10.1186/s13550-014-0029-3.
Fujiwara, K., Koyama, K., Suga, K., Ikemura, M., Saito, Y., Hino, A., Iwanari, H., Kusano-Arai, O., Mitsui, K., Kasahara, H., Fukayama, M., Kodama, T., Hamakubo, T., & Momose, T. (2014). A (90)Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy. EJNMMI research, 429. https://doi.org/10.1186/s13550-014-0029-3
Fujiwara, Kentaro, et al. "A (90)Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy." EJNMMI research vol. 4 (2014): 29. doi: https://doi.org/10.1186/s13550-014-0029-3
Fujiwara K, Koyama K, Suga K, Ikemura M, Saito Y, Hino A, Iwanari H, Kusano-Arai O, Mitsui K, Kasahara H, Fukayama M, Kodama T, Hamakubo T, Momose T. A (90)Y-labelled anti-ROBO1 monoclonal antibody exhibits antitumour activity against hepatocellular carcinoma xenografts during ROBO1-targeted radioimmunotherapy. EJNMMI Res. 2014 Jun 01;4:29. doi: 10.1186/s13550-014-0029-3. eCollection 2014. PMID: 25006547; PMCID: PMC4077627.
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Functional characterization of a yellow laccase from Leucoagaricus gongylophorus.

SpringerPlus

Ike PT, Moreira AC, de Almeida FG, Ferreira D, Birolli WG, Porto AL, Souza DH.
PMID: 26543788
Springerplus. 2015 Oct 30;4:654. doi: 10.1186/s40064-015-1464-y. eCollection 2015.

In this work we have identified, using mass spectrometry, two laccases produced by Leucoagaricus gongylophorus. One of them, Lac1Lg, was isolated, purified and characterized. Lac1Lg, a monomeric enzyme, was studied using ABTS and syringaldazine substrates. Lac1Lg presented kcat/Km almost...

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Ike PT, Moreira AC, de Almeida FG, et al. Functional characterization of a yellow laccase from Leucoagaricus gongylophorus. Springerplus. 2015;4:654doi: 10.1186/s40064-015-1464-y.
Ike, P. T., Moreira, A. C., de Almeida, F. G., Ferreira, D., Birolli, W. G., Porto, A. L., & Souza, D. H. (2015). Functional characterization of a yellow laccase from Leucoagaricus gongylophorus. SpringerPlus, 4654. https://doi.org/10.1186/s40064-015-1464-y
Ike, Priscila Tomie Leme, et al. "Functional characterization of a yellow laccase from Leucoagaricus gongylophorus." SpringerPlus vol. 4 (2015): 654. doi: https://doi.org/10.1186/s40064-015-1464-y
Ike PT, Moreira AC, de Almeida FG, Ferreira D, Birolli WG, Porto AL, Souza DH. Functional characterization of a yellow laccase from Leucoagaricus gongylophorus. Springerplus. 2015 Oct 30;4:654. doi: 10.1186/s40064-015-1464-y. eCollection 2015. PMID: 26543788; PMCID: PMC4628026.
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Reduction in gastrointestinal bleeding by development and implementation of a protocol for stress ulcer prophylaxis: a before-after study.

Journal of pharmaceutical health care and sciences

Ikemura M, Nakasako S, Seo R, Atsumi T, Ariyoshi K, Hashida T.
PMID: 26819744
J Pharm Health Care Sci. 2015 Dec 15;1:33. doi: 10.1186/s40780-015-0034-3. eCollection 2015.

BACKGROUND: The implementation of a protocol has been associated with improvements in the processes of care in clinical settings. Although stress ulcer prophylaxis is recommended for critically ill patients at high risk, there is currently no consensus on its...

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Ikemura M, Nakasako S, Seo R, et al. Reduction in gastrointestinal bleeding by development and implementation of a protocol for stress ulcer prophylaxis: a before-after study. J Pharm Health Care Sci. 2015;1:33doi: 10.1186/s40780-015-0034-3.
Ikemura, M., Nakasako, S., Seo, R., Atsumi, T., Ariyoshi, K., & Hashida, T. (2015). Reduction in gastrointestinal bleeding by development and implementation of a protocol for stress ulcer prophylaxis: a before-after study. Journal of pharmaceutical health care and sciences, 133. https://doi.org/10.1186/s40780-015-0034-3
Ikemura, Mai, et al. "Reduction in gastrointestinal bleeding by development and implementation of a protocol for stress ulcer prophylaxis: a before-after study." Journal of pharmaceutical health care and sciences vol. 1 (2015): 33. doi: https://doi.org/10.1186/s40780-015-0034-3
Ikemura M, Nakasako S, Seo R, Atsumi T, Ariyoshi K, Hashida T. Reduction in gastrointestinal bleeding by development and implementation of a protocol for stress ulcer prophylaxis: a before-after study. J Pharm Health Care Sci. 2015 Dec 15;1:33. doi: 10.1186/s40780-015-0034-3. eCollection 2015. PMID: 26819744; PMCID: PMC4729099.
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A case report of anorectal malignant melanoma with mucosal skipped lesion.

International journal of surgery case reports

Arakawa K, Kiyomatsu T, Ishihara S, Ikemura M, Hojo D, Takiyama H, Murono K, Otani K, Yasuda K, Nishikawa T, Tanaka T, Kawai K, Hata K, Nozawa H, Yamaguchi H, Watanabe T.
PMID: 27281362
Int J Surg Case Rep. 2016;24:206-10. doi: 10.1016/j.ijscr.2016.04.049. Epub 2016 Apr 30.

INTRODUCTION: We report our experience involving a case of relatively rare anorectal malignant melanoma with skipped lesion.PRESENTATION OF CASE: The patient was a 72-year-old man who had visited a local clinic complaining of a mass in the anal region,...

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Arakawa K, Kiyomatsu T, Ishihara S, et al. A case report of anorectal malignant melanoma with mucosal skipped lesion. Int J Surg Case Rep. 2016;24:206-10doi: 10.1016/j.ijscr.2016.04.049.
Arakawa, K., Kiyomatsu, T., Ishihara, S., Ikemura, M., Hojo, D., Takiyama, H., Murono, K., Otani, K., Yasuda, K., Nishikawa, T., Tanaka, T., Kawai, K., Hata, K., Nozawa, H., Yamaguchi, H., & Watanabe, T. (2016). A case report of anorectal malignant melanoma with mucosal skipped lesion. International journal of surgery case reports, 24206-10. https://doi.org/10.1016/j.ijscr.2016.04.049
Arakawa, Keiichi, et al. "A case report of anorectal malignant melanoma with mucosal skipped lesion." International journal of surgery case reports vol. 24 (2016): 206-10. doi: https://doi.org/10.1016/j.ijscr.2016.04.049
Arakawa K, Kiyomatsu T, Ishihara S, Ikemura M, Hojo D, Takiyama H, Murono K, Otani K, Yasuda K, Nishikawa T, Tanaka T, Kawai K, Hata K, Nozawa H, Yamaguchi H, Watanabe T. A case report of anorectal malignant melanoma with mucosal skipped lesion. Int J Surg Case Rep. 2016;24:206-10. doi: 10.1016/j.ijscr.2016.04.049. Epub 2016 Apr 30. PMID: 27281362; PMCID: PMC4906122.
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Dichloro(4,4'-dinonyl-2,2'-bipyridine-kappa2N,N')platinum(II).

Acta crystallographica. Section C, Crystal structure communications

Kato M, Ikemori M.
PMID: 12506219
Acta Crystallogr C. 2003 Jan;59:m25-6. doi: 10.1107/s010827010202156x. Epub 2002 Dec 17.

The title compound, [PtCl(2)(C(28)H(44)N(2))], is a new square-planar Pt(II) complex containing a bipyridine moiety with two long alkyl-chain substituents. The complex forms a segregated packing structure made up of the alkyl-chain layers and paired coordination sites.

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Kato M, Ikemori M. Dichloro(4,4'-dinonyl-2,2'-bipyridine-kappa2N,N')platinum(II). Acta Crystallogr C. 2002;59:m25-6doi: 10.1107/s010827010202156x.
Kato, M., & Ikemori, M. (2003). Dichloro(4,4'-dinonyl-2,2'-bipyridine-kappa2N,N')platinum(II). Acta crystallographica. Section C, Crystal structure communications, 59m25-6. https://doi.org/10.1107/s010827010202156x
Kato, Masako, and Ikemori, Mana. "Dichloro(4,4'-dinonyl-2,2'-bipyridine-kappa2N,N')platinum(II)." Acta crystallographica. Section C, Crystal structure communications vol. 59 (2003): m25-6. doi: https://doi.org/10.1107/s010827010202156x
Kato M, Ikemori M. Dichloro(4,4'-dinonyl-2,2'-bipyridine-kappa2N,N')platinum(II). Acta Crystallogr C. 2003 Jan;59:m25-6. doi: 10.1107/s010827010202156x. Epub 2002 Dec 17. PMID: 12506219.
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Stimulatory Effects of CO(2) Laser, Er:YAG Laser and Ga-Al-As Laser on Exposed Dentinal Tubule Orifices.

Journal of clinical biochemistry and nutrition

Matsui S, Kozuka M, Takayama J, Ueda K, Nakamura H, Ito K, Kimura M, Miura H, Tsujimoto Y, Kondoh T, Ikemi T, Matsushima K.
PMID: 18385831
J Clin Biochem Nutr. 2008 Mar;42(2):138-43. doi: 10.3164/jcbn.2008020.

We investigated the effects of lasers irradiation on the exposed dentinal tubule. Human tooth specimens with exposed dentinal tubule orifices were used. Three types of lasers (CO(2) laser, Er:YAG laser and Ga-Al-As laser) were employed. The parameters were 1.0...

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Matsui S, Kozuka M, Takayama J, et al. Stimulatory Effects of CO(2) Laser, Er:YAG Laser and Ga-Al-As Laser on Exposed Dentinal Tubule Orifices. J Clin Biochem Nutr. 2008;42(2):138-43doi: 10.3164/jcbn.2008020.
Matsui, S., Kozuka, M., Takayama, J., Ueda, K., Nakamura, H., Ito, K., Kimura, M., Miura, H., Tsujimoto, Y., Kondoh, T., Ikemi, T., & Matsushima, K. (2008). Stimulatory Effects of CO(2) Laser, Er:YAG Laser and Ga-Al-As Laser on Exposed Dentinal Tubule Orifices. Journal of clinical biochemistry and nutrition, 42(2), 138-43. https://doi.org/10.3164/jcbn.2008020
Matsui, Satoshi, et al. "Stimulatory Effects of CO(2) Laser, Er:YAG Laser and Ga-Al-As Laser on Exposed Dentinal Tubule Orifices." Journal of clinical biochemistry and nutrition vol. 42,2 (2008): 138-43. doi: https://doi.org/10.3164/jcbn.2008020
Matsui S, Kozuka M, Takayama J, Ueda K, Nakamura H, Ito K, Kimura M, Miura H, Tsujimoto Y, Kondoh T, Ikemi T, Matsushima K. Stimulatory Effects of CO(2) Laser, Er:YAG Laser and Ga-Al-As Laser on Exposed Dentinal Tubule Orifices. J Clin Biochem Nutr. 2008 Mar;42(2):138-43. doi: 10.3164/jcbn.2008020. PMID: 18385831; PMCID: PMC2266056.
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The possible role of androgenic hormones in maturation of alpha-adrenergic mechanisms in the rat.

Journal of neuroendocrinology

Kiem DT, Bartha L, Makara GB.
PMID: 19215384
J Neuroendocrinol. 1990 Aug 01;2(4):523-9. doi: 10.1111/j.1365-2826.1990.tb00443.x.

Abstract In order to get better characterization of androgenic hormones on the functionality of the alpha(2)-adrenergic system and widen our previous studies, we investigated the effect of clonidine on the growth hormone (GH) secretion in male Wistar rats of...

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Kiem DT, Bartha L, Makara GB. The possible role of androgenic hormones in maturation of alpha-adrenergic mechanisms in the rat. J Neuroendocrinol. 1990;2(4):523-9doi: 10.1111/j.1365-2826.1990.tb00443.x.
Kiem, D. T., Bartha, L., & Makara, G. B. (1990). The possible role of androgenic hormones in maturation of alpha-adrenergic mechanisms in the rat. Journal of neuroendocrinology, 2(4), 523-9. https://doi.org/10.1111/j.1365-2826.1990.tb00443.x
Kiem, D T, et al. "The possible role of androgenic hormones in maturation of alpha-adrenergic mechanisms in the rat." Journal of neuroendocrinology vol. 2,4 (1990): 523-9. doi: https://doi.org/10.1111/j.1365-2826.1990.tb00443.x
Kiem DT, Bartha L, Makara GB. The possible role of androgenic hormones in maturation of alpha-adrenergic mechanisms in the rat. J Neuroendocrinol. 1990 Aug 01;2(4):523-9. doi: 10.1111/j.1365-2826.1990.tb00443.x. PMID: 19215384.
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Community based diabetes risk assessment in Ogun state, Nigeria (World Diabetes Foundation project 08-321).

Indian journal of endocrinology and metabolism

Alebiosu OC, Familoni OB, Ogunsemi OO, Raimi TH, Balogun WO, Odusan O, Oguntona SA, Olunuga T, Kolawole BA, Ikem RT, Adeleye JO, Adesina OF, Adewuyi PA.
PMID: 23961481
Indian J Endocrinol Metab. 2013 Jul;17(4):653-8. doi: 10.4103/2230-8210.113756.

OBJECTIVE: The study assessed the risk of developing type 2 diabetes Mellitus in Ogun State, Nigeria.MATERIALS AND METHODS: Finnish Medical Association diabetes risk score was administered across 25 communities facilitated by non-communicable disease clinics established under a World Diabetes...

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Alebiosu OC, Familoni OB, Ogunsemi OO, et al. Community based diabetes risk assessment in Ogun state, Nigeria (World Diabetes Foundation project 08-321). Indian J Endocrinol Metab. 2013;17(4):653-8doi: 10.4103/2230-8210.113756.
Alebiosu, O. C., Familoni, O. B., Ogunsemi, O. O., Raimi, T. H., Balogun, W. O., Odusan, O., Oguntona, S. A., Olunuga, T., Kolawole, B. A., Ikem, R. T., Adeleye, J. O., Adesina, O. F., & Adewuyi, P. A. (2013). Community based diabetes risk assessment in Ogun state, Nigeria (World Diabetes Foundation project 08-321). Indian journal of endocrinology and metabolism, 17(4), 653-8. https://doi.org/10.4103/2230-8210.113756
Alebiosu, Olutayo C, et al. "Community based diabetes risk assessment in Ogun state, Nigeria (World Diabetes Foundation project 08-321)." Indian journal of endocrinology and metabolism vol. 17,4 (2013): 653-8. doi: https://doi.org/10.4103/2230-8210.113756
Alebiosu OC, Familoni OB, Ogunsemi OO, Raimi TH, Balogun WO, Odusan O, Oguntona SA, Olunuga T, Kolawole BA, Ikem RT, Adeleye JO, Adesina OF, Adewuyi PA. Community based diabetes risk assessment in Ogun state, Nigeria (World Diabetes Foundation project 08-321). Indian J Endocrinol Metab. 2013 Jul;17(4):653-8. doi: 10.4103/2230-8210.113756. PMID: 23961481; PMCID: PMC3743365.
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Two cases with hepatic amyloidosis suspected of having primary sclerosing cholangitis.

Hepatology research : the official journal of the Japan Society of Hepatology

Hirano K, Ikemura M, Mizuno S, Tada M, Isayama H, Watanabe T, Saito T, Kawahata S, Uchino R, Hamada T, Miyabayashi K, Sasaki T, Kogure H, Yamamoto N, Sasahira N, Koike K, Fukayama M, Sugawara Y, Kokudo N.
PMID: 23675805
Hepatol Res. 2013 Aug;43(8):911-6. doi: 10.1111/hepr.12034. Epub 2013 May 15.

Sclerogenic biliary changes in hepatic amyloidosis are seldom observed. Here, we report two recent cases initially suspected as primary sclerosing cholangitis (PSC), which were later diagnosed as hepatic amyloidosis (AL type). Case 1: On the basis of magnetic resonance...

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Hirano K, Ikemura M, Mizuno S, et al. Two cases with hepatic amyloidosis suspected of having primary sclerosing cholangitis. Hepatol Res. 2013;43(8):911-6doi: 10.1111/hepr.12034.
Hirano, K., Ikemura, M., Mizuno, S., Tada, M., Isayama, H., Watanabe, T., Saito, T., Kawahata, S., Uchino, R., Hamada, T., Miyabayashi, K., Sasaki, T., Kogure, H., Yamamoto, N., Sasahira, N., Koike, K., Fukayama, M., Sugawara, Y., & Kokudo, N. (2013). Two cases with hepatic amyloidosis suspected of having primary sclerosing cholangitis. Hepatology research : the official journal of the Japan Society of Hepatology, 43(8), 911-6. https://doi.org/10.1111/hepr.12034
Hirano, Kenji, et al. "Two cases with hepatic amyloidosis suspected of having primary sclerosing cholangitis." Hepatology research : the official journal of the Japan Society of Hepatology vol. 43,8 (2013): 911-6. doi: https://doi.org/10.1111/hepr.12034
Hirano K, Ikemura M, Mizuno S, Tada M, Isayama H, Watanabe T, Saito T, Kawahata S, Uchino R, Hamada T, Miyabayashi K, Sasaki T, Kogure H, Yamamoto N, Sasahira N, Koike K, Fukayama M, Sugawara Y, Kokudo N. Two cases with hepatic amyloidosis suspected of having primary sclerosing cholangitis. Hepatol Res. 2013 Aug;43(8):911-6. doi: 10.1111/hepr.12034. Epub 2013 May 15. PMID: 23675805.
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Effects of heat stress on ocular blood flow during exhaustive exercise.

Journal of sports science & medicine

Ikemura T, Hayashi N.
PMID: 24570622
J Sports Sci Med. 2014 Jan 20;13(1):172-9. eCollection 2014 Jan.

The hypothesis that heat stress reduces the ocular blood flow response to exhaustive exercise was tested by measuring ocular blood flow, blood pressure, and end- tidal carbon dioxide partial pressure (PETCO2) in 12 healthy males while they performed cycle...

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Ikemura T, Hayashi N. Effects of heat stress on ocular blood flow during exhaustive exercise. J Sports Sci Med. 2014;13(1):172-9
Ikemura, T., & Hayashi, N. (2014). Effects of heat stress on ocular blood flow during exhaustive exercise. Journal of sports science & medicine, 13(1), 172-9.
Ikemura, Tsukasa, and Hayashi, Naoyuki. "Effects of heat stress on ocular blood flow during exhaustive exercise." Journal of sports science & medicine vol. 13,1 (2014): 172-9.
Ikemura T, Hayashi N. Effects of heat stress on ocular blood flow during exhaustive exercise. J Sports Sci Med. 2014 Jan 20;13(1):172-9. eCollection 2014 Jan. PMID: 24570622; PMCID: PMC3918555.
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Showing 1 to 12 of 151 entries