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Showing 1 to 3 of 3 entries
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IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development .

Oncoimmunology

Boieri M, Ulvmoen A, Sudworth A, Lendrem C, Collin M, Dickinson AM, Kveberg L, Inngjerdingen M.
PMID: 28405496
Oncoimmunology. 2017 Jan 17;6(3):e1274478. doi: 10.1080/2162402X.2016.1274478. eCollection 2017.

NK cells have shown promise in therapy of hematological cancers, in particular against acute myeloid leukemia. In contrast, the more NK cell-resistant acute lymphoblastic leukemia (ALL) is difficult to treat with NK-cell-based therapies, and we hypothesized that pre-activation of...

The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical Overview.

Frontiers in immunology

Boieri M, Shah P, Dressel R, Inngjerdingen M.
PMID: 27625651
Front Immunol. 2016 Aug 30;7:333. doi: 10.3389/fimmu.2016.00333. eCollection 2016.

Bone marrow transplantation (BMT) is the only therapeutic option for many hematological malignancies, but its applicability is limited by life-threatening complications, such as graft-versus-host disease (GvHD). The last decades have seen great advances in the understanding of BMT and...

Tissue-Specific Expression Patterns of MicroRNA during Acute Graft-versus-Host Disease in the Rat.

Frontiers in immunology

Jalapothu D, Boieri M, Crossland RE, Shah P, Butt IA, Norden J, Dressel R, Dickinson AM, Inngjerdingen M.
PMID: 27695455
Front Immunol. 2016 Sep 16;7:361. doi: 10.3389/fimmu.2016.00361. eCollection 2016.

MicroRNAs (miRNA) have emerged as central regulators of diverse biological processes and contribute to driving pathology in several diseases. Acute graft-versus-host disease (aGvHD) represents a major complication after allogeneic hematopoietic stem cell transplantation, caused by alloreactive donor T cells...

Showing 1 to 3 of 3 entries