Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 105 entries
Sorted by: Best Match Show Resources per page
A second trigeminal CGRP receptor: function and expression of the AMY1 receptor.

Annals of clinical and translational neurology

Walker CS, Eftekhari S, Bower RL, Wilderman A, Insel PA, Edvinsson L, Waldvogel HJ, Jamaluddin MA, Russo AF, Hay DL.
PMID: 26125036
Ann Clin Transl Neurol. 2015 Jun;2(6):595-608. doi: 10.1002/acn3.197. Epub 2015 Apr 01.

OBJECTIVE: The trigeminovascular system plays a central role in migraine, a condition in need of new treatments. The neuropeptide, calcitonin gene-related peptide (CGRP), is proposed as causative in migraine and is the subject of intensive drug discovery efforts. This...

Assessing risk for preclinical β-amyloid pathology with .

Alzheimer's & dementia (Amsterdam, Netherlands)

Insel PS, Palmqvist S, Mackin RS, Nosheny RL, Hansson O, Weiner MW, Mattsson N.
PMID: 27722193
Alzheimers Dement (Amst). 2016 Aug 03;4:76-84. doi: 10.1016/j.dadm.2016.07.002. eCollection 2016.

INTRODUCTION: Clinical trials in Alzheimer's disease are aimed at early stages of disease, including preclinical Alzheimer's disease. The high cost and time required to screen large numbers of participants for Aβ pathology impede the development of novel drugs. This...

[With this simple trick all problems falling asleep are passé].

MMW Fortschritte der Medizin

Linsel A.
PMID: 27119873
MMW Fortschr Med. 2016 Mar 03;158(4):30. doi: 10.1007/s15006-016-7864-2.

No abstract available.

[Not Available].

MMW Fortschritte der Medizin

Linsel A.
PMID: 27646370
MMW Fortschr Med. 2016 Sep;158(16):35. doi: 10.1007/s15006-016-8715-x.

No abstract available.

Biomarkers and cognitive endpoints to optimize trials in Alzheimer's disease.

Annals of clinical and translational neurology

Insel PS, Mattsson N, Mackin RS, Kornak J, Nosheny R, Tosun-Turgut D, Donohue MC, Aisen PS, Weiner MW.
PMID: 26000325
Ann Clin Transl Neurol. 2015 May;2(5):534-47. doi: 10.1002/acn3.192. Epub 2015 Mar 21.

OBJECTIVE: To find the combination of candidate biomarkers and cognitive endpoints to maximize statistical power and minimize cost of clinical trials of healthy elders at risk for cognitive decline due to Alzheimer's disease.METHODS: Four-hundred and twelve cognitively normal participants...

Behavioral Research at NIMH Reorganizing the 'Bricks' to Advance Public Health.

APS observer

Insel T.
PMID: 17364016
APS Obs. 2005 Mar;18(3):10.

No abstract available.

Animal research in psychiatry and neurology.

CNS spectrums

Insel TR.
PMID: 18438308
CNS Spectr. 1999 Oct;4(10):18. doi: 10.1017/s109285290001230x.

No abstract available.

Disruptive insights in psychiatry: transforming a clinical discipline.

The Journal of clinical investigation

Insel TR.
PMID: 19339761
J Clin Invest. 2009 Apr;119(4):700-5. doi: 10.1172/JCI38832. Epub 2009 Apr 01.

Mental disorders such as schizophrenia, bipolar illness, and depression have become the predominant chronic diseases of young people, accounting for approximately 40% of the medical burden for people aged 15-44 in the United States and Canada. Research is transforming...

Control group design: enhancing rigor in research of mind-body therapies for depression.

Evidence-based complementary and alternative medicine : eCAM

Kinser PA, Robins JL.
PMID: 23662111
Evid Based Complement Alternat Med. 2013;2013:140467. doi: 10.1155/2013/140467. Epub 2013 Apr 07.

Although a growing body of research suggests that mind-body therapies may be appropriate to integrate into the treatment of depression, studies consistently lack methodological sophistication particularly in the area of control groups. In order to better understand the relationship...

MMW Fortschritte der Medizin

Linsel A.
PMID: 29663220
MMW Fortschr Med. 2018 Apr;160(7):28. doi: 10.1007/s15006-018-0419-y.

No abstract available.

MMW Fortschritte der Medizin

Linsel A.
PMID: 30302695
MMW Fortschr Med. 2018 Oct;160(17):28. doi: 10.1007/s15006-018-0971-5.

No abstract available.

Neuroanatomical spread of amyloid β and tau in Alzheimer's disease: implications for primary prevention.

Brain communications

Insel PS, Mormino EC, Aisen PS, Thompson WK, Donohue MC.
PMID: 32140682
Brain Commun. 2020;2(1):fcaa007. doi: 10.1093/braincomms/fcaa007. Epub 2020 Feb 06.

With recent advances in our understanding of the continuous pathophysiological changes that begin many years prior to symptom onset, it is now apparent that Alzheimer's disease cannot be adequately described by discrete clinical stages, but should also incorporate the...

Showing 1 to 12 of 105 entries