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Meaning of tumor protein 53-induced nuclear protein 1 in the molecular mechanism of gemcitabine sensitivity.

Molecular and clinical oncology

Nakaya N, Ishigaki Y, Nakajima H, Murakami M, Shimasaki T, Takata T, Ozaki M, Dusetti NJ, Iovanna JL, Motoo Y.
PMID: 24649130
Mol Clin Oncol. 2013 Jan;1(1):100-104. doi: 10.3892/mco.2012.8. Epub 2012 Aug 08.

Stress proteins of the pancreas, such as tumor protein 53-induced nuclear protein 1 (TP53INP1), are important factors in the invasion and metastasis of pancreatic cancer. TP53INP1 is a pro-apoptotic factor and is transcriptionally regulated in p53-dependent and -independent manners....

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Nakaya N, Ishigaki Y, Nakajima H, et al. Meaning of tumor protein 53-induced nuclear protein 1 in the molecular mechanism of gemcitabine sensitivity. Mol Clin Oncol. 2012;1(1):100-104doi: 10.3892/mco.2012.8.
Nakaya, N., Ishigaki, Y., Nakajima, H., Murakami, M., Shimasaki, T., Takata, T., Ozaki, M., Dusetti, N. J., Iovanna, J. L., & Motoo, Y. (2013). Meaning of tumor protein 53-induced nuclear protein 1 in the molecular mechanism of gemcitabine sensitivity. Molecular and clinical oncology, 1(1), 100-104. https://doi.org/10.3892/mco.2012.8
Nakaya, Naoki, et al. "Meaning of tumor protein 53-induced nuclear protein 1 in the molecular mechanism of gemcitabine sensitivity." Molecular and clinical oncology vol. 1,1 (2013): 100-104. doi: https://doi.org/10.3892/mco.2012.8
Nakaya N, Ishigaki Y, Nakajima H, Murakami M, Shimasaki T, Takata T, Ozaki M, Dusetti NJ, Iovanna JL, Motoo Y. Meaning of tumor protein 53-induced nuclear protein 1 in the molecular mechanism of gemcitabine sensitivity. Mol Clin Oncol. 2013 Jan;1(1):100-104. doi: 10.3892/mco.2012.8. Epub 2012 Aug 08. PMID: 24649130; PMCID: PMC3956314.
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Factors released by the tumor far microenvironment are decisive for pancreatic adenocarcinoma development and progression.

Oncoimmunology

Iovanna JL, Closa D.
PMID: 29147622
Oncoimmunology. 2017 Aug 08;6(11):e1358840. doi: 10.1080/2162402X.2017.1358840. eCollection 2017.

The REG3β protein was identified more than 2 decades ago, but its role in PDAC development was only recently reported. In Pancreatic Ductal Adenocarcinoma (PDAC), REG3β protein is expressed and released by the far microenvironment, which is situated out...

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Iovanna JL, Closa D. Factors released by the tumor far microenvironment are decisive for pancreatic adenocarcinoma development and progression. Oncoimmunology. 2017;6(11):e1358840doi: 10.1080/2162402X.2017.1358840.
Iovanna, J. L., & Closa, D. (2017). Factors released by the tumor far microenvironment are decisive for pancreatic adenocarcinoma development and progression. Oncoimmunology, 6(11), e1358840. https://doi.org/10.1080/2162402X.2017.1358840
Iovanna, Juan L, and Closa, Daniel. "Factors released by the tumor far microenvironment are decisive for pancreatic adenocarcinoma development and progression." Oncoimmunology vol. 6,11 (2017): e1358840. doi: https://doi.org/10.1080/2162402X.2017.1358840
Iovanna JL, Closa D. Factors released by the tumor far microenvironment are decisive for pancreatic adenocarcinoma development and progression. Oncoimmunology. 2017 Aug 08;6(11):e1358840. doi: 10.1080/2162402X.2017.1358840. eCollection 2017. PMID: 29147622; PMCID: PMC5674953.
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Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells.

Oncotarget

Boudouresque F, Siret C, Dobric A, Silvy F, Soubeyran P, Iovanna J, Lombardo D, Berthois Y.
PMID: 30542509
Oncotarget. 2018 Nov 13;9(89):35941-35961. doi: 10.18632/oncotarget.26310. eCollection 2018 Nov 13.

The microRNA-200 (miR-200) family is frequently down-regulated in tumors, including pancreatic adenocarcinomas (PDACs). In this study we have examined the mechanisms involved in the loss of miR-200s in tumoral pancreatic cells. Whereas miR-200 gene promoters appear methylated in mature...

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Boudouresque F, Siret C, Dobric A, et al. Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells. Oncotarget. 2018;9(89):35941-35961doi: 10.18632/oncotarget.26310.
Boudouresque, F., Siret, C., Dobric, A., Silvy, F., Soubeyran, P., Iovanna, J., Lombardo, D., & Berthois, Y. (2018). Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells. Oncotarget, 9(89), 35941-35961. https://doi.org/10.18632/oncotarget.26310
Boudouresque, Françoise, et al. "Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells." Oncotarget vol. 9,89 (2018): 35941-35961. doi: https://doi.org/10.18632/oncotarget.26310
Boudouresque F, Siret C, Dobric A, Silvy F, Soubeyran P, Iovanna J, Lombardo D, Berthois Y. Ribonuclease MCPiP1 contributes to the loss of micro-RNA-200 family members in pancreatic cancer cells. Oncotarget. 2018 Nov 13;9(89):35941-35961. doi: 10.18632/oncotarget.26310. eCollection 2018 Nov 13. PMID: 30542509; PMCID: PMC6267598.
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Efficiency and preference for alternative activities during schedule thinning with functional communication training.

Journal of applied behavior analysis

Simmons CA, Salvatore GL, Zangrillo AN.
PMID: 34694003
J Appl Behav Anal. 2022 Feb;55(1):101-120. doi: 10.1002/jaba.886. Epub 2021 Oct 24.

Functional communication training is an effective treatment for decreasing socially reinforced destructive behavior (Carr & Durand, 1985). Clinicians frequently use multiple schedules to thin the reinforcement schedule (Hanley et al., 2001). Individuals are often taught to wait for functional...

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Simmons CA, Salvatore GL, Zangrillo AN. Efficiency and preference for alternative activities during schedule thinning with functional communication training. J Appl Behav Anal. 2021;55(1):101-120doi: 10.1002/jaba.886.
Simmons, C. A., Salvatore, G. L., & Zangrillo, A. N. (2022). Efficiency and preference for alternative activities during schedule thinning with functional communication training. Journal of applied behavior analysis, 55(1), 101-120. https://doi.org/10.1002/jaba.886
Simmons, Christina A, et al. "Efficiency and preference for alternative activities during schedule thinning with functional communication training." Journal of applied behavior analysis vol. 55,1 (2022): 101-120. doi: https://doi.org/10.1002/jaba.886
Simmons CA, Salvatore GL, Zangrillo AN. Efficiency and preference for alternative activities during schedule thinning with functional communication training. J Appl Behav Anal. 2022 Feb;55(1):101-120. doi: 10.1002/jaba.886. Epub 2021 Oct 24. PMID: 34694003.
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Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer.

Translational oncology

Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ.
PMID: 34906890
Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11.

Pancreatic ductal adenocarcinoma (PDAC) patients are frequently treated by chemotherapy. Even if personalized therapy based on molecular analysis can be performed for some tumors, PDAC regimens selection is still mainly based on patients' performance status and expected efficacy. Therefore,...

Cite
Nicolle R, Gayet O, Bigonnet M, et al. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021;16:101315doi: 10.1016/j.tranon.2021.101315.
Nicolle, R., Gayet, O., Bigonnet, M., Roques, J., Chanez, B., Puleo, F., Augustin, J., Emile, J. F., Svrcek, M., Arsenijevic, T., Hammel, P., Rebours, V., Giovannini, M., Grandval, P., Dahan, L., Moutardier, V., Mitry, E., Van Laethem, J. L., Bachet, J. B., Cros, J., Iovanna, J., & Dusetti, N. J. (2021). Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Translational oncology, 16101315. https://doi.org/10.1016/j.tranon.2021.101315
Nicolle, R, et al. "Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer." Translational oncology vol. 16 (2021): 101315. doi: https://doi.org/10.1016/j.tranon.2021.101315
Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11. PMID: 34906890; PMCID: PMC8681024.
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Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer.

Translational oncology

Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ.
PMID: 34906890
Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11.

Pancreatic ductal adenocarcinoma (PDAC) patients are frequently treated by chemotherapy. Even if personalized therapy based on molecular analysis can be performed for some tumors, PDAC regimens selection is still mainly based on patients' performance status and expected efficacy. Therefore,...

Cite
Nicolle R, Gayet O, Bigonnet M, et al. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021;16:101315doi: 10.1016/j.tranon.2021.101315.
Nicolle, R., Gayet, O., Bigonnet, M., Roques, J., Chanez, B., Puleo, F., Augustin, J., Emile, J. F., Svrcek, M., Arsenijevic, T., Hammel, P., Rebours, V., Giovannini, M., Grandval, P., Dahan, L., Moutardier, V., Mitry, E., Van Laethem, J. L., Bachet, J. B., Cros, J., Iovanna, J., & Dusetti, N. J. (2021). Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Translational oncology, 16101315. https://doi.org/10.1016/j.tranon.2021.101315
Nicolle, R, et al. "Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer." Translational oncology vol. 16 (2021): 101315. doi: https://doi.org/10.1016/j.tranon.2021.101315
Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11. PMID: 34906890.
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DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study.

Cancers

Faleiro I, Roberto VP, Demirkol Canli S, Fraunhoffer NA, Iovanna J, Gure AO, Link W, Castelo-Branco P.
PMID: 34944974
Cancers (Basel). 2021 Dec 17;13(24). doi: 10.3390/cancers13246354.

Pancreatic cancer (PCA) is one of the most lethal malignancies worldwide with a 5-year survival rate of 9%. Despite the advances in the field, the need for an earlier detection and effective therapies is paramount. PCA high heterogeneity suggests...

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Faleiro I, Roberto VP, Demirkol Canli S, et al. DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study. Cancers (Basel). 2021;13(24)doi: 10.3390/cancers13246354.
Faleiro, I., Roberto, V. P., Demirkol Canli, S., Fraunhoffer, N. A., Iovanna, J., Gure, A. O., Link, W., & Castelo-Branco, P. (2021). DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study. Cancers, 13(24), . https://doi.org/10.3390/cancers13246354
Faleiro, Inês, et al. "DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study." Cancers vol. 13,24 (2021). doi: https://doi.org/10.3390/cancers13246354
Faleiro I, Roberto VP, Demirkol Canli S, Fraunhoffer NA, Iovanna J, Gure AO, Link W, Castelo-Branco P. DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study. Cancers (Basel). 2021 Dec 17;13(24). doi: 10.3390/cancers13246354. PMID: 34944974.
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Physician Perspectives on Severe Behavior and Restraint Use in a Hospital Setting for Patients with Autism Spectrum Disorder.

Journal of autism and developmental disorders

Salvatore GL, Simmons CA, Tremoulet PD.
PMID: 34657221
J Autism Dev Disord. 2021 Oct 16; doi: 10.1007/s10803-021-05327-8. Epub 2021 Oct 16.

Hospitals, with many features that can evoke severe behavior in patients with autism spectrum disorder (ASD), often use restraint as a behavior management strategy. Prior research on restraint in patients with ASD has primarily focused on children or specific...

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Salvatore GL, Simmons CA, Tremoulet PD. Physician Perspectives on Severe Behavior and Restraint Use in a Hospital Setting for Patients with Autism Spectrum Disorder. J Autism Dev Disord. 2021;doi: 10.1007/s10803-021-05327-8.
Salvatore, G. L., Simmons, C. A., & Tremoulet, P. D. (2021). Physician Perspectives on Severe Behavior and Restraint Use in a Hospital Setting for Patients with Autism Spectrum Disorder. Journal of autism and developmental disorders, . https://doi.org/10.1007/s10803-021-05327-8
Salvatore, Giovanna L, et al. "Physician Perspectives on Severe Behavior and Restraint Use in a Hospital Setting for Patients with Autism Spectrum Disorder." Journal of autism and developmental disorders vol. (2021). doi: https://doi.org/10.1007/s10803-021-05327-8
Salvatore GL, Simmons CA, Tremoulet PD. Physician Perspectives on Severe Behavior and Restraint Use in a Hospital Setting for Patients with Autism Spectrum Disorder. J Autism Dev Disord. 2021 Oct 16; doi: 10.1007/s10803-021-05327-8. Epub 2021 Oct 16. PMID: 34657221; PMCID: PMC8520455.
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Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function.

Biomolecules

Rizzuti B, Lan W, Santofimia-Castaño P, Zhou Z, Velázquez-Campoy A, Abián O, Peng L, Neira JL, Xia Y, Iovanna JL.
PMID: 34680086
Biomolecules. 2021 Oct 03;11(10). doi: 10.3390/biom11101453.

Intrinsically disordered proteins (IDPs) are emerging as attractive drug targets by virtue of their physiological ubiquity and their prevalence in various diseases, including cancer. NUPR1 is an IDP that localizes throughout the whole cell, and is involved in the...

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Rizzuti B, Lan W, Santofimia-Castaño P, et al. Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function. Biomolecules. 2021;11(10)doi: 10.3390/biom11101453.
Rizzuti, B., Lan, W., Santofimia-Castaño, P., Zhou, Z., Velázquez-Campoy, A., Abián, O., Peng, L., Neira, J. L., Xia, Y., & Iovanna, J. L. (2021). Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function. Biomolecules, 11(10), . https://doi.org/10.3390/biom11101453
Rizzuti, Bruno, et al. "Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function." Biomolecules vol. 11,10 (2021). doi: https://doi.org/10.3390/biom11101453
Rizzuti B, Lan W, Santofimia-Castaño P, Zhou Z, Velázquez-Campoy A, Abián O, Peng L, Neira JL, Xia Y, Iovanna JL. Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function. Biomolecules. 2021 Oct 03;11(10). doi: 10.3390/biom11101453. PMID: 34680086; PMCID: PMC8533202.
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Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer.

Translational oncology

Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ.
PMID: 34906890
Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11.

Pancreatic ductal adenocarcinoma (PDAC) patients are frequently treated by chemotherapy. Even if personalized therapy based on molecular analysis can be performed for some tumors, PDAC regimens selection is still mainly based on patients' performance status and expected efficacy. Therefore,...

Cite
Nicolle R, Gayet O, Bigonnet M, et al. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021;16:101315doi: 10.1016/j.tranon.2021.101315.
Nicolle, R., Gayet, O., Bigonnet, M., Roques, J., Chanez, B., Puleo, F., Augustin, J., Emile, J. F., Svrcek, M., Arsenijevic, T., Hammel, P., Rebours, V., Giovannini, M., Grandval, P., Dahan, L., Moutardier, V., Mitry, E., Van Laethem, J. L., Bachet, J. B., Cros, J., Iovanna, J., & Dusetti, N. J. (2021). Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Translational oncology, 16101315. https://doi.org/10.1016/j.tranon.2021.101315
Nicolle, R, et al. "Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer." Translational oncology vol. 16 (2021): 101315. doi: https://doi.org/10.1016/j.tranon.2021.101315
Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11. PMID: 34906890.
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Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer.

Translational oncology

Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ.
PMID: 34906890
Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11.

Pancreatic ductal adenocarcinoma (PDAC) patients are frequently treated by chemotherapy. Even if personalized therapy based on molecular analysis can be performed for some tumors, PDAC regimens selection is still mainly based on patients' performance status and expected efficacy. Therefore,...

Cite
Nicolle R, Gayet O, Bigonnet M, et al. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021;16:101315doi: 10.1016/j.tranon.2021.101315.
Nicolle, R., Gayet, O., Bigonnet, M., Roques, J., Chanez, B., Puleo, F., Augustin, J., Emile, J. F., Svrcek, M., Arsenijevic, T., Hammel, P., Rebours, V., Giovannini, M., Grandval, P., Dahan, L., Moutardier, V., Mitry, E., Van Laethem, J. L., Bachet, J. B., Cros, J., Iovanna, J., & Dusetti, N. J. (2021). Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Translational oncology, 16101315. https://doi.org/10.1016/j.tranon.2021.101315
Nicolle, R, et al. "Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer." Translational oncology vol. 16 (2021): 101315. doi: https://doi.org/10.1016/j.tranon.2021.101315
Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11. PMID: 34906890; PMCID: PMC8681024.
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Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer.

Translational oncology

Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ.
PMID: 34906890
Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11.

Pancreatic ductal adenocarcinoma (PDAC) patients are frequently treated by chemotherapy. Even if personalized therapy based on molecular analysis can be performed for some tumors, PDAC regimens selection is still mainly based on patients' performance status and expected efficacy. Therefore,...

Cite
Nicolle R, Gayet O, Bigonnet M, et al. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021;16:101315doi: 10.1016/j.tranon.2021.101315.
Nicolle, R., Gayet, O., Bigonnet, M., Roques, J., Chanez, B., Puleo, F., Augustin, J., Emile, J. F., Svrcek, M., Arsenijevic, T., Hammel, P., Rebours, V., Giovannini, M., Grandval, P., Dahan, L., Moutardier, V., Mitry, E., Van Laethem, J. L., Bachet, J. B., Cros, J., Iovanna, J., & Dusetti, N. J. (2021). Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Translational oncology, 16101315. https://doi.org/10.1016/j.tranon.2021.101315
Nicolle, R, et al. "Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer." Translational oncology vol. 16 (2021): 101315. doi: https://doi.org/10.1016/j.tranon.2021.101315
Nicolle R, Gayet O, Bigonnet M, Roques J, Chanez B, Puleo F, Augustin J, Emile JF, Svrcek M, Arsenijevic T, Hammel P, Rebours V, Giovannini M, Grandval P, Dahan L, Moutardier V, Mitry E, Van Laethem JL, Bachet JB, Cros J, Iovanna J, Dusetti NJ. Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer. Transl Oncol. 2021 Dec 11;16:101315. doi: 10.1016/j.tranon.2021.101315. Epub 2021 Dec 11. PMID: 34906890.
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