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Showing 1 to 12 of 25 entries
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Infant Dextromethorphan and Dextrorphan Exposure via Breast Milk From Mothers Who Are CYP2D6 Extensive Metabolizers.

Journal of clinical pharmacology

Shum S, Yadav A, Fay E, Moreni S, Mao J, Czuba L, Wang C, Isoherranen N, Hebert MF.
PMID: 34889461
J Clin Pharmacol. 2021 Dec 08; doi: 10.1002/jcph.2012. Epub 2021 Dec 08.

The risk of infant exposure to dextromethorphan (DM) and its active metabolite, dextrorphan (DX), through breast milk has not been evaluated. In this study, bound and unbound DM and DX concentrations in breast milk and plasma at 2 hours...

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Shum S, Yadav A, Fay E, et al. Infant Dextromethorphan and Dextrorphan Exposure via Breast Milk From Mothers Who Are CYP2D6 Extensive Metabolizers. J Clin Pharmacol. 2021;doi: 10.1002/jcph.2012.
Shum, S., Yadav, A., Fay, E., Moreni, S., Mao, J., Czuba, L., Wang, C., Isoherranen, N., & Hebert, M. F. (2021). Infant Dextromethorphan and Dextrorphan Exposure via Breast Milk From Mothers Who Are CYP2D6 Extensive Metabolizers. Journal of clinical pharmacology, . https://doi.org/10.1002/jcph.2012
Shum, Sara, et al. "Infant Dextromethorphan and Dextrorphan Exposure via Breast Milk From Mothers Who Are CYP2D6 Extensive Metabolizers." Journal of clinical pharmacology vol. (2021). doi: https://doi.org/10.1002/jcph.2012
Shum S, Yadav A, Fay E, Moreni S, Mao J, Czuba L, Wang C, Isoherranen N, Hebert MF. Infant Dextromethorphan and Dextrorphan Exposure via Breast Milk From Mothers Who Are CYP2D6 Extensive Metabolizers. J Clin Pharmacol. 2021 Dec 08; doi: 10.1002/jcph.2012. Epub 2021 Dec 08. PMID: 34889461.
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Corrigendum to "In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation" [Biochem. Pharmacol. 123(2017)85-96].

Biochemical pharmacology

Sager JE, Tripathy S, Price LSL, Nath A, Chang J, Stephenson-Famy A, Isoherranen N.
PMID: 33161206
Biochem Pharmacol. 2021 Jan;183:114306. doi: 10.1016/j.bcp.2020.114306. Epub 2020 Nov 05.

No abstract available.

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Sager JE, Tripathy S, Price LSL, et al. Corrigendum to "In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation" [Biochem. Pharmacol. 123(2017)85-96]. Biochem Pharmacol. 2020;183:114306doi: 10.1016/j.bcp.2020.114306.
Sager, J. E., Tripathy, S., Price, L. S. L., Nath, A., Chang, J., Stephenson-Famy, A., & Isoherranen, N. (2021). Corrigendum to "In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation" [Biochem. Pharmacol. 123(2017)85-96]. Biochemical pharmacology, 183114306. https://doi.org/10.1016/j.bcp.2020.114306
Sager, Jennifer E, et al. "Corrigendum to "In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation" [Biochem. Pharmacol. 123(2017)85-96]." Biochemical pharmacology vol. 183 (2021): 114306. doi: https://doi.org/10.1016/j.bcp.2020.114306
Sager JE, Tripathy S, Price LSL, Nath A, Chang J, Stephenson-Famy A, Isoherranen N. Corrigendum to "In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation" [Biochem. Pharmacol. 123(2017)85-96]. Biochem Pharmacol. 2021 Jan;183:114306. doi: 10.1016/j.bcp.2020.114306. Epub 2020 Nov 05. PMID: 33161206; PMCID: PMC7769866.
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Rule of three I's: a mnemonic aid in undergraduate teaching of lower limb wounds.

Journal of wound care

Salava A, Isoherranen K.
PMID: 34881993
J Wound Care. 2021 Dec 02;30(12):1030. doi: 10.12968/jowc.2021.30.12.1030.

No abstract available.

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Salava A, Isoherranen K. Rule of three I's: a mnemonic aid in undergraduate teaching of lower limb wounds. J Wound Care. 2021;30(12):1030doi: 10.12968/jowc.2021.30.12.1030.
Salava, A., & Isoherranen, K. (2021). Rule of three I's: a mnemonic aid in undergraduate teaching of lower limb wounds. Journal of wound care, 30(12), 1030. https://doi.org/10.12968/jowc.2021.30.12.1030
Salava, Alexander, and Isoherranen, Kirsi. "Rule of three I's: a mnemonic aid in undergraduate teaching of lower limb wounds." Journal of wound care vol. 30,12 (2021): 1030. doi: https://doi.org/10.12968/jowc.2021.30.12.1030
Salava A, Isoherranen K. Rule of three I's: a mnemonic aid in undergraduate teaching of lower limb wounds. J Wound Care. 2021 Dec 02;30(12):1030. doi: 10.12968/jowc.2021.30.12.1030. PMID: 34881993.
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[Not Available].

Duodecim; laaketieteellinen aikakauskirja

Isoherranen K, Koskenmies S, Höök-Nikanne J.
PMID: 18027740
Duodecim. 2007;123(17):2131-2.

No abstract available.

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Isoherranen K, Koskenmies S, Höök-Nikanne J. Hankalahoitoiset säärihaavat. [Not Available]. Duodecim. 2007;123(17):2131-2
Isoherranen, K., Koskenmies, S., & Höök-Nikanne, J. (2007). Hankalahoitoiset säärihaavat. [Not Available]. Duodecim; laaketieteellinen aikakauskirja, 123(17), 2131-2.
Isoherranen, Kirsi, et al. "Hankalahoitoiset säärihaavat." [Not Available]. Duodecim; laaketieteellinen aikakauskirja vol. 123,17 (2007): 2131-2.
Isoherranen K, Koskenmies S, Höök-Nikanne J. Hankalahoitoiset säärihaavat. [Not Available]. Duodecim. 2007;123(17):2131-2. Finnish. PMID: 18027740.
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Variation and consistency of female preferences for simulated courtship songs in Drosophila virilis.

Animal behaviour

Aspi J, Hoikkala A, Isoherranen E.
PMID: 10196051
Anim Behav. 1999 Mar;57(3):619-625. doi: 10.1006/anbe.1998.0981.

To study the variation and consistency of song preferences in Drosophila virilis females, we played them species-specific song and songs with modified sound pulses and/or interpulse intervals on 3 consecutive days. Species-specific song was played again on the fourth...

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Aspi J, Hoikkala A, Isoherranen E. Variation and consistency of female preferences for simulated courtship songs in Drosophila virilis. Anim Behav. 1999;57(3):619-625doi: 10.1006/anbe.1998.0981.
Aspi, J., Hoikkala, A., & Isoherranen, E. (1999). Variation and consistency of female preferences for simulated courtship songs in Drosophila virilis. Animal behaviour, 57(3), 619-625. https://doi.org/10.1006/anbe.1998.0981
Aspi, et al. "Variation and consistency of female preferences for simulated courtship songs in Drosophila virilis." Animal behaviour vol. 57,3 (1999): 619-625. doi: https://doi.org/10.1006/anbe.1998.0981
Aspi J, Hoikkala A, Isoherranen E. Variation and consistency of female preferences for simulated courtship songs in Drosophila virilis. Anim Behav. 1999 Mar;57(3):619-625. doi: 10.1006/anbe.1998.0981. PMID: 10196051.
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Aldehyde Oxidase Contributes to All-.

Drug metabolism and disposition: the biological fate of chemicals

Zhong G, Seaman CJ, Paragas EM, Xi H, Herpoldt KL, King NP, Jones JP, Isoherranen N.
PMID: 33355213
Drug Metab Dispos. 2021 Mar;49(3):202-211. doi: 10.1124/dmd.120.000296. Epub 2020 Dec 18.

All-

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Zhong G, Seaman CJ, Paragas EM, et al. Aldehyde Oxidase Contributes to All-. Drug Metab Dispos. 2020;49(3):202-211doi: 10.1124/dmd.120.000296.
Zhong, G., Seaman, C. J., Paragas, E. M., Xi, H., Herpoldt, K. L., King, N. P., Jones, J. P., & Isoherranen, N. (2021). Aldehyde Oxidase Contributes to All-. Drug metabolism and disposition: the biological fate of chemicals, 49(3), 202-211. https://doi.org/10.1124/dmd.120.000296
Zhong, Guo, et al. "Aldehyde Oxidase Contributes to All-." Drug metabolism and disposition: the biological fate of chemicals vol. 49,3 (2021): 202-211. doi: https://doi.org/10.1124/dmd.120.000296
Zhong G, Seaman CJ, Paragas EM, Xi H, Herpoldt KL, King NP, Jones JP, Isoherranen N. Aldehyde Oxidase Contributes to All-. Drug Metab Dispos. 2021 Mar;49(3):202-211. doi: 10.1124/dmd.120.000296. Epub 2020 Dec 18. PMID: 33355213; PMCID: PMC7885020.
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Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites.

Therapeutic drug monitoring

Fay EE, Czuba LC, Sager JE, Shum S, Stephenson-Famy A, Isoherranen N.
PMID: 33814540
Ther Drug Monit. 2021 Dec 01;43(6):780-788. doi: 10.1097/FTD.0000000000000885.

BACKGROUND: Bupropion (BUP) is a chiral antidepressant and smoking cessation aide with benefits and side effects correlated with parent and active metabolite concentrations. BUP is metabolized by CYP2B6, CYP2C19, and CYP3A4 to hydroxy-BUP (OH-BUP) as well as by 11β-hydroxysteroid...

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Fay EE, Czuba LC, Sager JE, et al. Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites. Ther Drug Monit. 2021;43(6):780-788doi: 10.1097/FTD.0000000000000885.
Fay, E. E., Czuba, L. C., Sager, J. E., Shum, S., Stephenson-Famy, A., & Isoherranen, N. (2021). Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites. Therapeutic drug monitoring, 43(6), 780-788. https://doi.org/10.1097/FTD.0000000000000885
Fay, Emily E, et al. "Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites." Therapeutic drug monitoring vol. 43,6 (2021): 780-788. doi: https://doi.org/10.1097/FTD.0000000000000885
Fay EE, Czuba LC, Sager JE, Shum S, Stephenson-Famy A, Isoherranen N. Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites. Ther Drug Monit. 2021 Dec 01;43(6):780-788. doi: 10.1097/FTD.0000000000000885. PMID: 33814540; PMCID: PMC8426418.
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The Role of Negative Pressure Wound Therapy (NPWT) in the Management of Vasculitic Wounds: Case Series of Eight Patients.

The international journal of lower extremity wounds

Isoherranen K, Kluger N, Hannula-Jouppi K, Väkevä L.
PMID: 34878340
Int J Low Extrem Wounds. 2021 Dec 08;15347346211063700. doi: 10.1177/15347346211063700. Epub 2021 Dec 08.

Vasculitic ulcers belong to the category of atypical ulcers and are traditionally very slow to heal. The aim of this study is to retrospectively analyze the files of eight patients with vasculitic ulcers treated with negative pressure wound therapy

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Isoherranen K, Kluger N, Hannula-Jouppi K, et al. The Role of Negative Pressure Wound Therapy (NPWT) in the Management of Vasculitic Wounds: Case Series of Eight Patients. Int J Low Extrem Wounds. 2021;15347346211063700doi: 10.1177/15347346211063700.
Isoherranen, K., Kluger, N., Hannula-Jouppi, K., & Väkevä, L. (2021). The Role of Negative Pressure Wound Therapy (NPWT) in the Management of Vasculitic Wounds: Case Series of Eight Patients. The international journal of lower extremity wounds, 15347346211063700. https://doi.org/10.1177/15347346211063700
Isoherranen, Kirsi, et al. "The Role of Negative Pressure Wound Therapy (NPWT) in the Management of Vasculitic Wounds: Case Series of Eight Patients." The international journal of lower extremity wounds vol. (2021): 15347346211063700. doi: https://doi.org/10.1177/15347346211063700
Isoherranen K, Kluger N, Hannula-Jouppi K, Väkevä L. The Role of Negative Pressure Wound Therapy (NPWT) in the Management of Vasculitic Wounds: Case Series of Eight Patients. Int J Low Extrem Wounds. 2021 Dec 08;15347346211063700. doi: 10.1177/15347346211063700. Epub 2021 Dec 08. PMID: 34878340.
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Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system.

Scientific reports

Imaoka T, Huang W, Shum S, Hailey DW, Chang SY, Chapron A, Yeung CK, Himmelfarb J, Isoherranen N, Kelly EJ.
PMID: 34725352
Sci Rep. 2021 Nov 01;11(1):21356. doi: 10.1038/s41598-021-00338-y.

Opioid overdose, dependence, and addiction are a major public health crisis. Patients with chronic kidney disease (CKD) are at high risk of opioid overdose, therefore novel methods that provide accurate prediction of renal clearance (CL

Cite
Imaoka T, Huang W, Shum S, et al. Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system. Sci Rep. 2021;11(1):21356doi: 10.1038/s41598-021-00338-y.
Imaoka, T., Huang, W., Shum, S., Hailey, D. W., Chang, S. Y., Chapron, A., Yeung, C. K., Himmelfarb, J., Isoherranen, N., & Kelly, E. J. (2021). Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system. Scientific reports, 11(1), 21356. https://doi.org/10.1038/s41598-021-00338-y
Imaoka, Tomoki, et al. "Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system." Scientific reports vol. 11,1 (2021): 21356. doi: https://doi.org/10.1038/s41598-021-00338-y
Imaoka T, Huang W, Shum S, Hailey DW, Chang SY, Chapron A, Yeung CK, Himmelfarb J, Isoherranen N, Kelly EJ. Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system. Sci Rep. 2021 Nov 01;11(1):21356. doi: 10.1038/s41598-021-00338-y. PMID: 34725352; PMCID: PMC8560754.
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Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions.

Journal of lipid research

Honarbakhsh M, Ericsson A, Zhong G, Isoherranen N, Zhu C, Bromberg Y, Van Buiten C, Malta K, Joseph L, Sampath H, Lackey AI, Storch J, Vetriani C, Chikindas ML, Breslin P, Quadro L.
PMID: 33587919
J Lipid Res. 2021 Feb 13;62:100046. doi: 10.1016/j.jlr.2021.100046. Epub 2021 Feb 13.

Lecithin:retinol acyltransferase and retinol-binding protein enable vitamin A (VA) storage and transport, respectively, maintaining tissue homeostasis of retinoids (VA derivatives). The precarious VA status of the lecithin:retinol acyltransferase-deficient (Lrat

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Honarbakhsh M, Ericsson A, Zhong G, et al. Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions. J Lipid Res. 2021;62:100046doi: 10.1016/j.jlr.2021.100046.
Honarbakhsh, M., Ericsson, A., Zhong, G., Isoherranen, N., Zhu, C., Bromberg, Y., Van Buiten, C., Malta, K., Joseph, L., Sampath, H., Lackey, A. I., Storch, J., Vetriani, C., Chikindas, M. L., Breslin, P., & Quadro, L. (2021). Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions. Journal of lipid research, 62100046. https://doi.org/10.1016/j.jlr.2021.100046
Honarbakhsh, Maryam, et al. "Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions." Journal of lipid research vol. 62 (2021): 100046. doi: https://doi.org/10.1016/j.jlr.2021.100046
Honarbakhsh M, Ericsson A, Zhong G, Isoherranen N, Zhu C, Bromberg Y, Van Buiten C, Malta K, Joseph L, Sampath H, Lackey AI, Storch J, Vetriani C, Chikindas ML, Breslin P, Quadro L. Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions. J Lipid Res. 2021 Feb 13;62:100046. doi: 10.1016/j.jlr.2021.100046. Epub 2021 Feb 13. PMID: 33587919; PMCID: PMC8020483.
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Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes.

Cannabis and cannabinoid research

Huang W, Czuba LC, Manuzak JA, Martin JN, Hunt PW, Klatt NR, Isoherranen N.
PMID: 34793254
Cannabis Cannabinoid Res. 2021 Nov 18; doi: 10.1089/can.2021.0068. Epub 2021 Nov 18.

No abstract available.

Cite
Huang W, Czuba LC, Manuzak JA, et al. Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes. Cannabis Cannabinoid Res. 2021;doi: 10.1089/can.2021.0068.
Huang, W., Czuba, L. C., Manuzak, J. A., Martin, J. N., Hunt, P. W., Klatt, N. R., & Isoherranen, N. (2021). Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes. Cannabis and cannabinoid research, . https://doi.org/10.1089/can.2021.0068
Huang, Weize, et al. "Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes." Cannabis and cannabinoid research vol. (2021). doi: https://doi.org/10.1089/can.2021.0068
Huang W, Czuba LC, Manuzak JA, Martin JN, Hunt PW, Klatt NR, Isoherranen N. Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes. Cannabis Cannabinoid Res. 2021 Nov 18; doi: 10.1089/can.2021.0068. Epub 2021 Nov 18. PMID: 34793254.
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Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system.

Scientific reports

Imaoka T, Huang W, Shum S, Hailey DW, Chang SY, Chapron A, Yeung CK, Himmelfarb J, Isoherranen N, Kelly EJ.
PMID: 34725352
Sci Rep. 2021 Nov 01;11(1):21356. doi: 10.1038/s41598-021-00338-y.

Opioid overdose, dependence, and addiction are a major public health crisis. Patients with chronic kidney disease (CKD) are at high risk of opioid overdose, therefore novel methods that provide accurate prediction of renal clearance (CL

Cite
Imaoka T, Huang W, Shum S, et al. Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system. Sci Rep. 2021;11(1):21356doi: 10.1038/s41598-021-00338-y.
Imaoka, T., Huang, W., Shum, S., Hailey, D. W., Chang, S. Y., Chapron, A., Yeung, C. K., Himmelfarb, J., Isoherranen, N., & Kelly, E. J. (2021). Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system. Scientific reports, 11(1), 21356. https://doi.org/10.1038/s41598-021-00338-y
Imaoka, Tomoki, et al. "Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system." Scientific reports vol. 11,1 (2021): 21356. doi: https://doi.org/10.1038/s41598-021-00338-y
Imaoka T, Huang W, Shum S, Hailey DW, Chang SY, Chapron A, Yeung CK, Himmelfarb J, Isoherranen N, Kelly EJ. Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system. Sci Rep. 2021 Nov 01;11(1):21356. doi: 10.1038/s41598-021-00338-y. PMID: 34725352; PMCID: PMC8560754.
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Showing 1 to 12 of 25 entries