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Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation.

JCI insight

Gerarduzzi C, Kumar RK, Trivedi P, Ajay AK, Iyer A, Boswell S, Hutchinson JN, Waikar SS, Vaidya VS.
PMID: 28422762
JCI Insight. 2017 Apr 20;2(8). doi: 10.1172/jci.insight.90299. eCollection 2017 Apr 20.

Secreted modular calcium-binding protein 2 (SMOC2) belongs to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins whose members are known to modulate cell-matrix interactions. We report that SMOC2 is upregulated in the kidney tubular...

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Gerarduzzi C, Kumar RK, Trivedi P, et al. Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI Insight. 2017;2(8)doi: 10.1172/jci.insight.90299.
Gerarduzzi, C., Kumar, R. K., Trivedi, P., Ajay, A. K., Iyer, A., Boswell, S., Hutchinson, J. N., Waikar, S. S., & Vaidya, V. S. (2017). Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI insight, 2(8), . https://doi.org/10.1172/jci.insight.90299
Gerarduzzi, Casimiro, et al. "Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation." JCI insight vol. 2,8 (2017). doi: https://doi.org/10.1172/jci.insight.90299
Gerarduzzi C, Kumar RK, Trivedi P, Ajay AK, Iyer A, Boswell S, Hutchinson JN, Waikar SS, Vaidya VS. Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI Insight. 2017 Apr 20;2(8). doi: 10.1172/jci.insight.90299. eCollection 2017 Apr 20. PMID: 28422762; PMCID: PMC5396522.
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Diagnosis of an imprinted-gene syndrome by a novel bioinformatics analysis of whole-genome sequences from a family trio.

Molecular genetics & genomic medicine

Bodian DL, Solomon BD, Khromykh A, Thach DC, Iyer RK, Link K, Baker RL, Baveja R, Vockley JG, Niederhuber JE.
PMID: 25614875
Mol Genet Genomic Med. 2014 Nov;2(6):530-8. doi: 10.1002/mgg3.107. Epub 2014 Aug 26.

Whole-genome sequencing and whole-exome sequencing are becoming more widely applied in clinical medicine to help diagnose rare genetic diseases. Identification of the underlying causative mutations by genome-wide sequencing is greatly facilitated by concurrent analysis of multiple family members, most...

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Bodian DL, Solomon BD, Khromykh A, et al. Diagnosis of an imprinted-gene syndrome by a novel bioinformatics analysis of whole-genome sequences from a family trio. Mol Genet Genomic Med. 2014;2(6):530-8doi: 10.1002/mgg3.107.
Bodian, D. L., Solomon, B. D., Khromykh, A., Thach, D. C., Iyer, R. K., Link, K., Baker, R. L., Baveja, R., Vockley, J. G., & Niederhuber, J. E. (2014). Diagnosis of an imprinted-gene syndrome by a novel bioinformatics analysis of whole-genome sequences from a family trio. Molecular genetics & genomic medicine, 2(6), 530-8. https://doi.org/10.1002/mgg3.107
Bodian, Dale L, et al. "Diagnosis of an imprinted-gene syndrome by a novel bioinformatics analysis of whole-genome sequences from a family trio." Molecular genetics & genomic medicine vol. 2,6 (2014): 530-8. doi: https://doi.org/10.1002/mgg3.107
Bodian DL, Solomon BD, Khromykh A, Thach DC, Iyer RK, Link K, Baker RL, Baveja R, Vockley JG, Niederhuber JE. Diagnosis of an imprinted-gene syndrome by a novel bioinformatics analysis of whole-genome sequences from a family trio. Mol Genet Genomic Med. 2014 Nov;2(6):530-8. doi: 10.1002/mgg3.107. Epub 2014 Aug 26. PMID: 25614875; PMCID: PMC4303223.
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A paradoxical relationship between Resveratrol and copper (II) with respect to degradation of DNA and RNA.

F1000Research

Subramaniam S, Vohra I, Iyer A, Nair NK, Mittra I.
PMID: 27134724
F1000Res. 2015 Oct 27;4:1145. doi: 10.12688/f1000research.7202.2. eCollection 2015.

Resveratrol (R), a plant polyphenol, is known to reduce Cu (II) to Cu (I) generating reactive oxygen species that can cleave plasmid DNA. Here we report a surprising observation of a paradoxical relationship between R and Cu whereby plasmid...

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Subramaniam S, Vohra I, Iyer A, et al. A paradoxical relationship between Resveratrol and copper (II) with respect to degradation of DNA and RNA. F1000Res. 2015;4:1145doi: 10.12688/f1000research.7202.2.
Subramaniam, S., Vohra, I., Iyer, A., Nair, N. K., & Mittra, I. (2015). A paradoxical relationship between Resveratrol and copper (II) with respect to degradation of DNA and RNA. F1000Research, 41145. https://doi.org/10.12688/f1000research.7202.2
Subramaniam, Siddharth, et al. "A paradoxical relationship between Resveratrol and copper (II) with respect to degradation of DNA and RNA." F1000Research vol. 4 (2015): 1145. doi: https://doi.org/10.12688/f1000research.7202.2
Subramaniam S, Vohra I, Iyer A, Nair NK, Mittra I. A paradoxical relationship between Resveratrol and copper (II) with respect to degradation of DNA and RNA. F1000Res. 2015 Oct 27;4:1145. doi: 10.12688/f1000research.7202.2. eCollection 2015. PMID: 27134724; PMCID: PMC4833056.
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Corrigendum: Control of eight predominant Eimeria spp. involved in economic coccidiosis of broiler chicken by a chemically characterized essential oil.

Journal of applied microbiology

Barbour EK, Bragg RR, Karrouf G, Iyer A, Azhar E, Harakeh S, Kumosani T.
PMID: 26490358
J Appl Microbiol. 2015 Nov;119(5):1454. doi: 10.1111/jam.12949.

No abstract available.

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Barbour EK, Bragg RR, Karrouf G, et al. Corrigendum: Control of eight predominant Eimeria spp. involved in economic coccidiosis of broiler chicken by a chemically characterized essential oil. J Appl Microbiol. 2015;119(5):1454doi: 10.1111/jam.12949.
Barbour, E. K., Bragg, R. R., Karrouf, G., Iyer, A., Azhar, E., Harakeh, S., & Kumosani, T. (2015). Corrigendum: Control of eight predominant Eimeria spp. involved in economic coccidiosis of broiler chicken by a chemically characterized essential oil. Journal of applied microbiology, 119(5), 1454. https://doi.org/10.1111/jam.12949
Barbour, E K, et al. "Corrigendum: Control of eight predominant Eimeria spp. involved in economic coccidiosis of broiler chicken by a chemically characterized essential oil." Journal of applied microbiology vol. 119,5 (2015): 1454. doi: https://doi.org/10.1111/jam.12949
Barbour EK, Bragg RR, Karrouf G, Iyer A, Azhar E, Harakeh S, Kumosani T. Corrigendum: Control of eight predominant Eimeria spp. involved in economic coccidiosis of broiler chicken by a chemically characterized essential oil. J Appl Microbiol. 2015 Nov;119(5):1454. doi: 10.1111/jam.12949. PMID: 26490358.
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Anisotropic metamaterial optical fibers.

Optics express

Pratap D, Anantha Ramakrishna S, Pollock JG, Iyer AK.
PMID: 25968741
Opt Express. 2015 Apr 06;23(7):9074-85. doi: 10.1364/OE.23.009074.

Internal physical structure can drastically modify the properties of waveguides: photonic crystal fibers are able to confine light inside a hollow air core by Bragg scattering from a periodic array of holes, while metamaterial loaded waveguides for microwaves can...

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Pratap D, Anantha Ramakrishna S, Pollock JG, et al. Anisotropic metamaterial optical fibers. Opt Express. 2015;23(7):9074-85doi: 10.1364/OE.23.009074.
Pratap, D., Anantha Ramakrishna, S., Pollock, J. G., & Iyer, A. K. (2015). Anisotropic metamaterial optical fibers. Optics express, 23(7), 9074-85. https://doi.org/10.1364/OE.23.009074
Pratap, Dheeraj, et al. "Anisotropic metamaterial optical fibers." Optics express vol. 23,7 (2015): 9074-85. doi: https://doi.org/10.1364/OE.23.009074
Pratap D, Anantha Ramakrishna S, Pollock JG, Iyer AK. Anisotropic metamaterial optical fibers. Opt Express. 2015 Apr 06;23(7):9074-85. doi: 10.1364/OE.23.009074. PMID: 25968741.
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Genome Sequences of Six Paenibacillus larvae Siphoviridae Phages.

Genome announcements

Carson S, Bruff E, DeFoor W, Dums J, Groth A, Hatfield T, Iyer A, Joshi K, McAdams S, Miles D, Miller D, Oufkir A, Raynor B, Riley S, Roland S, Rozier H, Talley S, Miller ES.
PMID: 26089405
Genome Announc. 2015 Jun 18;3(3). doi: 10.1128/genomeA.00101-15.

Six sequenced and annotated genomes of Paenibacillus larvae phages isolated from the combs of American foulbrood-diseased beehives are 37 to 45 kbp and have approximately 42% G+C content and 60 to 74 protein-coding genes. Phage Lily is most divergent...

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Carson S, Bruff E, DeFoor W, et al. Genome Sequences of Six Paenibacillus larvae Siphoviridae Phages. Genome Announc. 2015;3(3)doi: 10.1128/genomeA.00101-15.
Carson, S., Bruff, E., DeFoor, W., Dums, J., Groth, A., Hatfield, T., Iyer, A., Joshi, K., McAdams, S., Miles, D., Miller, D., Oufkir, A., Raynor, B., Riley, S., Roland, S., Rozier, H., Talley, S., & Miller, E. S. (2015). Genome Sequences of Six Paenibacillus larvae Siphoviridae Phages. Genome announcements, 3(3), . https://doi.org/10.1128/genomeA.00101-15
Carson, Susan, et al. "Genome Sequences of Six Paenibacillus larvae Siphoviridae Phages." Genome announcements vol. 3,3 (2015). doi: https://doi.org/10.1128/genomeA.00101-15
Carson S, Bruff E, DeFoor W, Dums J, Groth A, Hatfield T, Iyer A, Joshi K, McAdams S, Miles D, Miller D, Oufkir A, Raynor B, Riley S, Roland S, Rozier H, Talley S, Miller ES. Genome Sequences of Six Paenibacillus larvae Siphoviridae Phages. Genome Announc. 2015 Jun 18;3(3). doi: 10.1128/genomeA.00101-15. PMID: 26089405; PMCID: PMC4472882.
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Genome Sequences of Gordonia Phages Bowser and Schwabeltier.

Genome announcements

Montgomery MT, Pope WH, Arnold ZM, Basina A, Iyer AM, Stoner TH, Kasturiarachi NS, Pressimone CA, Schiebel JG, Furbee EC, Grubb SR, Warner MH, Garlena RA, Russell DA, Jacobs-Sera D, Hatfull GF.
PMID: 27516498
Genome Announc. 2016 Aug 11;4(4). doi: 10.1128/genomeA.00596-16.

Gordonia phages Bowser and Schwabeltier are newly isolated phages infecting Gordonia terrae 3612. Bowser and Schwabeltier have similar siphoviral morphologies and their genomes are related to each other, but not to other phages. Their lysis cassettes are atypically situated...

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Montgomery MT, Pope WH, Arnold ZM, et al. Genome Sequences of Gordonia Phages Bowser and Schwabeltier. Genome Announc. 2016;4(4)doi: 10.1128/genomeA.00596-16.
Montgomery, M. T., Pope, W. H., Arnold, Z. M., Basina, A., Iyer, A. M., Stoner, T. H., Kasturiarachi, N. S., Pressimone, C. A., Schiebel, J. G., Furbee, E. C., Grubb, S. R., Warner, M. H., Garlena, R. A., Russell, D. A., Jacobs-Sera, D., & Hatfull, G. F. (2016). Genome Sequences of Gordonia Phages Bowser and Schwabeltier. Genome announcements, 4(4), . https://doi.org/10.1128/genomeA.00596-16
Montgomery, Matthew T, et al. "Genome Sequences of Gordonia Phages Bowser and Schwabeltier." Genome announcements vol. 4,4 (2016). doi: https://doi.org/10.1128/genomeA.00596-16
Montgomery MT, Pope WH, Arnold ZM, Basina A, Iyer AM, Stoner TH, Kasturiarachi NS, Pressimone CA, Schiebel JG, Furbee EC, Grubb SR, Warner MH, Garlena RA, Russell DA, Jacobs-Sera D, Hatfull GF. Genome Sequences of Gordonia Phages Bowser and Schwabeltier. Genome Announc. 2016 Aug 11;4(4). doi: 10.1128/genomeA.00596-16. PMID: 27516498; PMCID: PMC4982277.
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Optical Characterization of Commercial Lithiated Graphite Battery Electrodes and in Situ Fiber Optic Evanescent Wave Spectroscopy.

ACS applied materials & interfaces

Ghannoum A, Norris RC, Iyer K, Zdravkova L, Yu A, Nieva P.
PMID: 27379859
ACS Appl Mater Interfaces. 2016 Jul 27;8(29):18763-9. doi: 10.1021/acsami.6b03638. Epub 2016 Jul 13.

Optical characterization of graphite anodes in lithium ion batteries (LIB) is presented here for potential use in estimating their state of charge (SOC). The characterization is based on reflectance spectroscopy of the anode of commercial LIB cells and in...

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Ghannoum A, Norris RC, Iyer K, et al. Optical Characterization of Commercial Lithiated Graphite Battery Electrodes and in Situ Fiber Optic Evanescent Wave Spectroscopy. ACS Appl Mater Interfaces. 2016;8(29):18763-9doi: 10.1021/acsami.6b03638.
Ghannoum, A., Norris, R. C., Iyer, K., Zdravkova, L., Yu, A., & Nieva, P. (2016). Optical Characterization of Commercial Lithiated Graphite Battery Electrodes and in Situ Fiber Optic Evanescent Wave Spectroscopy. ACS applied materials & interfaces, 8(29), 18763-9. https://doi.org/10.1021/acsami.6b03638
Ghannoum, AbdulRahman, et al. "Optical Characterization of Commercial Lithiated Graphite Battery Electrodes and in Situ Fiber Optic Evanescent Wave Spectroscopy." ACS applied materials & interfaces vol. 8,29 (2016): 18763-9. doi: https://doi.org/10.1021/acsami.6b03638
Ghannoum A, Norris RC, Iyer K, Zdravkova L, Yu A, Nieva P. Optical Characterization of Commercial Lithiated Graphite Battery Electrodes and in Situ Fiber Optic Evanescent Wave Spectroscopy. ACS Appl Mater Interfaces. 2016 Jul 27;8(29):18763-9. doi: 10.1021/acsami.6b03638. Epub 2016 Jul 13. PMID: 27379859.
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Corrigendum to "Evaluation of a Salmonella Enteritidis vaccine and related ELISA for respective induction and assessment of acquired immunity to the vaccine and/or Echinacea purpurea in Awassi Ewes" [Vaccine 33 (2015) 2228-2231].

Vaccine

Barbour EK, Abou Assi CA, Shaib H, Hamadeh S, Murtada M, Mahmoud G, Yaghmoor S, Iyer A, Harakeh S, Kumosani T.
PMID: 27329183
Vaccine. 2016 Jul 25;34(34):4085. doi: 10.1016/j.vaccine.2016.06.044. Epub 2016 Jun 18.

No abstract available.

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Barbour EK, Abou Assi CA, Shaib H, et al. Corrigendum to "Evaluation of a Salmonella Enteritidis vaccine and related ELISA for respective induction and assessment of acquired immunity to the vaccine and/or Echinacea purpurea in Awassi Ewes" [Vaccine 33 (2015) 2228-2231]. Vaccine. 2016;34(34):4085doi: 10.1016/j.vaccine.2016.06.044.
Barbour, E. K., Abou Assi, C. A., Shaib, H., Hamadeh, S., Murtada, M., Mahmoud, G., Yaghmoor, S., Iyer, A., Harakeh, S., & Kumosani, T. (2016). Corrigendum to "Evaluation of a Salmonella Enteritidis vaccine and related ELISA for respective induction and assessment of acquired immunity to the vaccine and/or Echinacea purpurea in Awassi Ewes" [Vaccine 33 (2015) 2228-2231]. Vaccine, 34(34), 4085. https://doi.org/10.1016/j.vaccine.2016.06.044
Barbour, Elie K, et al. "Corrigendum to "Evaluation of a Salmonella Enteritidis vaccine and related ELISA for respective induction and assessment of acquired immunity to the vaccine and/or Echinacea purpurea in Awassi Ewes" [Vaccine 33 (2015) 2228-2231]." Vaccine vol. 34,34 (2016): 4085. doi: https://doi.org/10.1016/j.vaccine.2016.06.044
Barbour EK, Abou Assi CA, Shaib H, Hamadeh S, Murtada M, Mahmoud G, Yaghmoor S, Iyer A, Harakeh S, Kumosani T. Corrigendum to "Evaluation of a Salmonella Enteritidis vaccine and related ELISA for respective induction and assessment of acquired immunity to the vaccine and/or Echinacea purpurea in Awassi Ewes" [Vaccine 33 (2015) 2228-2231]. Vaccine. 2016 Jul 25;34(34):4085. doi: 10.1016/j.vaccine.2016.06.044. Epub 2016 Jun 18. PMID: 27329183.
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Spectroelectrochemical sensing based on multimode selectivity simultaneously achievable in a single device. 13. Detection of aqueous iron by in situ complexation with 2,2'-bipyridine.

Analytical chemistry

Richardson JN, Dyer AL, Stegemiller ML, Zudans I, Seliskar CJ, Heineman WR.
PMID: 12139036
Anal Chem. 2002 Jul 15;74(14):3330-5. doi: 10.1021/ac0111715.

A spectroelectrochemical sensor with attenuated total reflectance at an indium-doped tin oxide (ITO) optically transparent electrode coated with a thin film of Nafion has been demonstrated for the determination of aqueous iron ion. The novelty of this sensor stems...

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Richardson JN, Dyer AL, Stegemiller ML, et al. Spectroelectrochemical sensing based on multimode selectivity simultaneously achievable in a single device. 13. Detection of aqueous iron by in situ complexation with 2,2'-bipyridine. Anal Chem. 2002;74(14):3330-5doi: 10.1021/ac0111715.
Richardson, J. N., Dyer, A. L., Stegemiller, M. L., Zudans, I., Seliskar, C. J., & Heineman, W. R. (2002). Spectroelectrochemical sensing based on multimode selectivity simultaneously achievable in a single device. 13. Detection of aqueous iron by in situ complexation with 2,2'-bipyridine. Analytical chemistry, 74(14), 3330-5. https://doi.org/10.1021/ac0111715
Richardson, John N, et al. "Spectroelectrochemical sensing based on multimode selectivity simultaneously achievable in a single device. 13. Detection of aqueous iron by in situ complexation with 2,2'-bipyridine." Analytical chemistry vol. 74,14 (2002): 3330-5. doi: https://doi.org/10.1021/ac0111715
Richardson JN, Dyer AL, Stegemiller ML, Zudans I, Seliskar CJ, Heineman WR. Spectroelectrochemical sensing based on multimode selectivity simultaneously achievable in a single device. 13. Detection of aqueous iron by in situ complexation with 2,2'-bipyridine. Anal Chem. 2002 Jul 15;74(14):3330-5. doi: 10.1021/ac0111715. PMID: 12139036.
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Understanding affirmative action.

Annual review of psychology

Crosby FJ, Iyer A, Sincharoen S.
PMID: 16318608
Annu Rev Psychol. 2006;57:585-611. doi: 10.1146/annurev.psych.57.102904.190029.

Affirmative action is a controversial and often poorly understood policy. It is also a policy that has been widely studied by social scientists. In this review, we outline how affirmative action operates in employment and education settings and consider...

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Crosby FJ, Iyer A, Sincharoen S. Understanding affirmative action. Annu Rev Psychol. 2006;57:585-611doi: 10.1146/annurev.psych.57.102904.190029.
Crosby, F. J., Iyer, A., & Sincharoen, S. (2006). Understanding affirmative action. Annual review of psychology, 57585-611. https://doi.org/10.1146/annurev.psych.57.102904.190029
Crosby, Faye J, et al. "Understanding affirmative action." Annual review of psychology vol. 57 (2006): 585-611. doi: https://doi.org/10.1146/annurev.psych.57.102904.190029
Crosby FJ, Iyer A, Sincharoen S. Understanding affirmative action. Annu Rev Psychol. 2006;57:585-611. doi: 10.1146/annurev.psych.57.102904.190029. PMID: 16318608.
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Evolution of a metastable phase with a magnetic phase coexistence phenomenon and its unusual sensitivity to magnetic field cycling in the alloys Tb(5 - x)Lu(x)Si3 (x ≤ 0.7).

Journal of physics. Condensed matter : an Institute of Physics journal

Mukherjee K, Iyer KK, Sampathkumaran EV.
PMID: 21540520
J Phys Condens Matter. 2011 May 25;23(20):206002. doi: 10.1088/0953-8984/23/20/206002. Epub 2011 May 04.

Recently, we reported an anomalous enhancement of the positive magnetoresistance beyond a critical magnetic field in Tb(5)Si(3) in the magnetically ordered state, attributable to 'inverse metamagnetism'. This results in unusual magnetic hysteresis loops for the pressurized specimens, which are...

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Mukherjee K, Iyer KK, Sampathkumaran EV. Evolution of a metastable phase with a magnetic phase coexistence phenomenon and its unusual sensitivity to magnetic field cycling in the alloys Tb(5 - x)Lu(x)Si3 (x ≤ 0.7). J Phys Condens Matter. 2011;23(20):206002doi: 10.1088/0953-8984/23/20/206002.
Mukherjee, K., Iyer, K. K., & Sampathkumaran, E. V. (2011). Evolution of a metastable phase with a magnetic phase coexistence phenomenon and its unusual sensitivity to magnetic field cycling in the alloys Tb(5 - x)Lu(x)Si3 (x ≤ 0.7). Journal of physics. Condensed matter : an Institute of Physics journal, 23(20), 206002. https://doi.org/10.1088/0953-8984/23/20/206002
Mukherjee, K, et al. "Evolution of a metastable phase with a magnetic phase coexistence phenomenon and its unusual sensitivity to magnetic field cycling in the alloys Tb(5 - x)Lu(x)Si3 (x ≤ 0.7)." Journal of physics. Condensed matter : an Institute of Physics journal vol. 23,20 (2011): 206002. doi: https://doi.org/10.1088/0953-8984/23/20/206002
Mukherjee K, Iyer KK, Sampathkumaran EV. Evolution of a metastable phase with a magnetic phase coexistence phenomenon and its unusual sensitivity to magnetic field cycling in the alloys Tb(5 - x)Lu(x)Si3 (x ≤ 0.7). J Phys Condens Matter. 2011 May 25;23(20):206002. doi: 10.1088/0953-8984/23/20/206002. Epub 2011 May 04. PMID: 21540520.
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