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A High-throughput workflow for CRISPR/Cas9 mediated combinatorial promoter replacements and phenotype characterization in yeast.

Biotechnology journal

Kuivanen J, Holmström S, Lehtinen B, Penttilä M, Jäntti J.
PMID: 29729128
Biotechnol J. 2018 May 05;e1700593. doi: 10.1002/biot.201700593. Epub 2018 May 05.

Due to the rapidly increasing sequence information on gene variants generated by evolution and our improved abilities to engineer novel biological activities, microbial cells can be evolved for the production of a growing spectrum of compounds. For high productivity,...

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Kuivanen J, Holmström S, Lehtinen B, et al. A High-throughput workflow for CRISPR/Cas9 mediated combinatorial promoter replacements and phenotype characterization in yeast. Biotechnol J. 2018;e1700593doi: 10.1002/biot.201700593.
Kuivanen, J., Holmström, S., Lehtinen, B., Penttilä, M., & Jäntti, J. (2018). A High-throughput workflow for CRISPR/Cas9 mediated combinatorial promoter replacements and phenotype characterization in yeast. Biotechnology journal, e1700593. https://doi.org/10.1002/biot.201700593
Kuivanen, Joosu, et al. "A High-throughput workflow for CRISPR/Cas9 mediated combinatorial promoter replacements and phenotype characterization in yeast." Biotechnology journal vol. (2018): e1700593. doi: https://doi.org/10.1002/biot.201700593
Kuivanen J, Holmström S, Lehtinen B, Penttilä M, Jäntti J. A High-throughput workflow for CRISPR/Cas9 mediated combinatorial promoter replacements and phenotype characterization in yeast. Biotechnol J. 2018 May 05;e1700593. doi: 10.1002/biot.201700593. Epub 2018 May 05. PMID: 29729128.
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[No title available]

The Journal of pharmacology and experimental therapeutics

Tarvainen I, Nunn RC, Tuominen RK, Jäntti MH, Talman V.
PMID: 34697230
J Pharmacol Exp Ther. 2021 Oct 25; doi: 10.1124/jpet.121.000848. Epub 2021 Oct 25.

Colorectal cancer is the third most commonly occurring cancer in men and the second in women. The global burden of colorectal cancer is projected to increase to over 2 million new cases with over 1 million deaths within the...

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Tarvainen I, Nunn RC, Tuominen RK, et al. . J Pharmacol Exp Ther. 2021;doi: 10.1124/jpet.121.000848.
Tarvainen, I., Nunn, R. C., Tuominen, R. K., Jäntti, M. H., & Talman, V. (2021). . The Journal of pharmacology and experimental therapeutics, . https://doi.org/10.1124/jpet.121.000848
Tarvainen, Ilari, et al. "." The Journal of pharmacology and experimental therapeutics vol. (2021). doi: https://doi.org/10.1124/jpet.121.000848
Tarvainen I, Nunn RC, Tuominen RK, Jäntti MH, Talman V. . J Pharmacol Exp Ther. 2021 Oct 25; doi: 10.1124/jpet.121.000848. Epub 2021 Oct 25. PMID: 34697230.
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Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort.

British journal of anaesthesia

Saviluoto A, Jäntti H, Kirves H, Setälä P, Nurmi JO.
PMID: 34656323
Br J Anaesth. 2022 Feb;128(2):e135-e142. doi: 10.1016/j.bja.2021.08.029. Epub 2021 Oct 14.

BACKGROUND: Pre-hospital anaesthesia is a core competency of helicopter emergency medical services (HEMS). Whether physician pre-hospital anaesthesia case volume affects outcomes is unknown in this setting. We aimed to investigate whether physician case volume was associated with differences in...

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Saviluoto A, Jäntti H, Kirves H, et al. Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort. Br J Anaesth. 2021;128(2):e135-e142doi: 10.1016/j.bja.2021.08.029.
Saviluoto, A., Jäntti, H., Kirves, H., Setälä, P., & Nurmi, J. O. (2022). Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort. British journal of anaesthesia, 128(2), e135-e142. https://doi.org/10.1016/j.bja.2021.08.029
Saviluoto, Anssi, et al. "Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort." British journal of anaesthesia vol. 128,2 (2022): e135-e142. doi: https://doi.org/10.1016/j.bja.2021.08.029
Saviluoto A, Jäntti H, Kirves H, Setälä P, Nurmi JO. Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort. Br J Anaesth. 2022 Feb;128(2):e135-e142. doi: 10.1016/j.bja.2021.08.029. Epub 2021 Oct 14. PMID: 34656323.
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Experiences with external hip protectors in homes for the aged: a report from Finland.

Journal of the American Medical Directors Association

Mäki-Jokela P, Valvanne J, Jäntti P, Heikinheimo R.
PMID: 12807564
J Am Med Dir Assoc. 2002 Jan-Feb;3(1):29-31.

OBJECTIVE: Three observational studies were performed to examine the use and effectiveness of external hip protectors intended to prevent hip fractures.METHODS: Data were collected by: (1) questionnaire to health centers or homes for the aged to which hip protectors...

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Mäki-Jokela P, Valvanne J, Jäntti P, et al. Experiences with external hip protectors in homes for the aged: a report from Finland. J Am Med Dir Assoc. 2002;3(1):29-31
Mäki-Jokela, P., Valvanne, J., Jäntti, P., & Heikinheimo, R. (2002). Experiences with external hip protectors in homes for the aged: a report from Finland. Journal of the American Medical Directors Association, 3(1), 29-31.
Mäki-Jokela, Päivi, et al. "Experiences with external hip protectors in homes for the aged: a report from Finland." Journal of the American Medical Directors Association vol. 3,1 (2002): 29-31.
Mäki-Jokela P, Valvanne J, Jäntti P, Heikinheimo R. Experiences with external hip protectors in homes for the aged: a report from Finland. J Am Med Dir Assoc. 2002 Jan-Feb;3(1):29-31. PMID: 12807564.
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Corrigendum to "Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells" [Biomed. Pharmacother. 131 (2020) 110788].

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Rostami J, Jäntti M, Cui H, Rinne MK, Kukkonen JP, Falk A, Erlandsson A, Myöhänen T.
PMID: 33246737
Biomed Pharmacother. 2021 Jan;133:111019. doi: 10.1016/j.biopha.2020.111019. Epub 2020 Nov 24.

No abstract available.

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Rostami J, Jäntti M, Cui H, et al. Corrigendum to "Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells" [Biomed. Pharmacother. 131 (2020) 110788]. Biomed Pharmacother. 2020;133:111019doi: 10.1016/j.biopha.2020.111019.
Rostami, J., Jäntti, M., Cui, H., Rinne, M. K., Kukkonen, J. P., Falk, A., Erlandsson, A., & Myöhänen, T. (2021). Corrigendum to "Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells" [Biomed. Pharmacother. 131 (2020) 110788]. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 133111019. https://doi.org/10.1016/j.biopha.2020.111019
Rostami, Jinar, et al. "Corrigendum to "Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells" [Biomed. Pharmacother. 131 (2020) 110788]." Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 133 (2021): 111019. doi: https://doi.org/10.1016/j.biopha.2020.111019
Rostami J, Jäntti M, Cui H, Rinne MK, Kukkonen JP, Falk A, Erlandsson A, Myöhänen T. Corrigendum to "Prolyl oligopeptidase inhibition by KYP-2407 increases alpha-synuclein fibril degradation in neuron-like cells" [Biomed. Pharmacother. 131 (2020) 110788]. Biomed Pharmacother. 2021 Jan;133:111019. doi: 10.1016/j.biopha.2020.111019. Epub 2020 Nov 24. PMID: 33246737.
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Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics.

ACS medicinal chemistry letters

Tarvainen I, Zimmermann T, Heinonen P, Jäntti MH, Yli-Kauhaluoma J, Talman V, Franzyk H, Tuominen RK, Christensen SB.
PMID: 32435369
ACS Med Chem Lett. 2019 Dec 23;11(5):671-677. doi: 10.1021/acsmedchemlett.9b00554. eCollection 2020 May 14.

Targeting cytotoxic 4β-phorbol esters toward cancer tissue was attempted by conjugating a 4β-pborbol derivative with substrates for the proteases prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) expressed in cancer tissue. The hydrophilic peptide moiety was hypothesized to prevent...

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Tarvainen I, Zimmermann T, Heinonen P, et al. Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics. ACS Med Chem Lett. 2019;11(5):671-677doi: 10.1021/acsmedchemlett.9b00554.
Tarvainen, I., Zimmermann, T., Heinonen, P., Jäntti, M. H., Yli-Kauhaluoma, J., Talman, V., Franzyk, H., Tuominen, R. K., & Christensen, S. B. (2020). Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics. ACS medicinal chemistry letters, 11(5), 671-677. https://doi.org/10.1021/acsmedchemlett.9b00554
Tarvainen, Ilari, et al. "Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics." ACS medicinal chemistry letters vol. 11,5 (2020): 671-677. doi: https://doi.org/10.1021/acsmedchemlett.9b00554
Tarvainen I, Zimmermann T, Heinonen P, Jäntti MH, Yli-Kauhaluoma J, Talman V, Franzyk H, Tuominen RK, Christensen SB. Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics. ACS Med Chem Lett. 2019 Dec 23;11(5):671-677. doi: 10.1021/acsmedchemlett.9b00554. eCollection 2020 May 14. PMID: 32435369; PMCID: PMC7236034.
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Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort.

British journal of anaesthesia

Saviluoto A, Jäntti H, Kirves H, Setälä P, Nurmi JO.
PMID: 34656323
Br J Anaesth. 2022 Feb;128(2):e135-e142. doi: 10.1016/j.bja.2021.08.029. Epub 2021 Oct 14.

BACKGROUND: Pre-hospital anaesthesia is a core competency of helicopter emergency medical services (HEMS). Whether physician pre-hospital anaesthesia case volume affects outcomes is unknown in this setting. We aimed to investigate whether physician case volume was associated with differences in...

Cite
Saviluoto A, Jäntti H, Kirves H, et al. Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort. Br J Anaesth. 2021;128(2):e135-e142doi: 10.1016/j.bja.2021.08.029.
Saviluoto, A., Jäntti, H., Kirves, H., Setälä, P., & Nurmi, J. O. (2022). Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort. British journal of anaesthesia, 128(2), e135-e142. https://doi.org/10.1016/j.bja.2021.08.029
Saviluoto, Anssi, et al. "Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort." British journal of anaesthesia vol. 128,2 (2022): e135-e142. doi: https://doi.org/10.1016/j.bja.2021.08.029
Saviluoto A, Jäntti H, Kirves H, Setälä P, Nurmi JO. Association between case volume and mortality in pre-hospital anaesthesia management: a retrospective observational cohort. Br J Anaesth. 2022 Feb;128(2):e135-e142. doi: 10.1016/j.bja.2021.08.029. Epub 2021 Oct 14. PMID: 34656323.
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Reply to: High levels of plasma biomarkers at 24 h were found to be strong predictors of 90-day mortality: beware of some potential confounders!.

Annals of intensive care

Jäntti T, Harjola VP, Haapio M, Lassus J.
PMID: 33723683
Ann Intensive Care. 2021 Mar 15;11(1):46. doi: 10.1186/s13613-021-00839-z.

No abstract available.

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Jäntti T, Harjola VP, Haapio M, et al. Reply to: High levels of plasma biomarkers at 24 h were found to be strong predictors of 90-day mortality: beware of some potential confounders!. Ann Intensive Care. 2021;11(1):46doi: 10.1186/s13613-021-00839-z.
Jäntti, T., Harjola, V. P., Haapio, M., & Lassus, J. (2021). Reply to: High levels of plasma biomarkers at 24 h were found to be strong predictors of 90-day mortality: beware of some potential confounders!. Annals of intensive care, 11(1), 46. https://doi.org/10.1186/s13613-021-00839-z
Jäntti, Toni, et al. "Reply to: High levels of plasma biomarkers at 24 h were found to be strong predictors of 90-day mortality: beware of some potential confounders!." Annals of intensive care vol. 11,1 (2021): 46. doi: https://doi.org/10.1186/s13613-021-00839-z
Jäntti T, Harjola VP, Haapio M, Lassus J. Reply to: High levels of plasma biomarkers at 24 h were found to be strong predictors of 90-day mortality: beware of some potential confounders!. Ann Intensive Care. 2021 Mar 15;11(1):46. doi: 10.1186/s13613-021-00839-z. PMID: 33723683; PMCID: PMC7960823.
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Ultra-Low-Power Wide Range Backscatter Communication Using Cellular Generated Carrier.

Sensors (Basel, Switzerland)

Sheikh MU, Xie B, Ruttik K, Yiğitler H, Jäntti R, Hämäläinen J.
PMID: 33920074
Sensors (Basel). 2021 Apr 10;21(8). doi: 10.3390/s21082663.

With the popularization of Internet-of-things (IoT) and wireless communication systems, a diverse set of applications in smart cities are emerging to improve the city-life. These applications usually require a large coverage area and minimal operation and maintenance cost. To...

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Sheikh MU, Xie B, Ruttik K, et al. Ultra-Low-Power Wide Range Backscatter Communication Using Cellular Generated Carrier. Sensors (Basel). 2021;21(8)doi: 10.3390/s21082663.
Sheikh, M. U., Xie, B., Ruttik, K., Yiğitler, H., Jäntti, R., & Hämäläinen, J. (2021). Ultra-Low-Power Wide Range Backscatter Communication Using Cellular Generated Carrier. Sensors (Basel, Switzerland), 21(8), . https://doi.org/10.3390/s21082663
Sheikh, Muhammad Usman, et al. "Ultra-Low-Power Wide Range Backscatter Communication Using Cellular Generated Carrier." Sensors (Basel, Switzerland) vol. 21,8 (2021). doi: https://doi.org/10.3390/s21082663
Sheikh MU, Xie B, Ruttik K, Yiğitler H, Jäntti R, Hämäläinen J. Ultra-Low-Power Wide Range Backscatter Communication Using Cellular Generated Carrier. Sensors (Basel). 2021 Apr 10;21(8). doi: 10.3390/s21082663. PMID: 33920074; PMCID: PMC8069532.
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Prey depletion by the foraging of the Eurasian treecreeper, Certhia familiaris, on tree-trunk arthropods.

Oecologia

Jäntti A, Aho T, Hakkarainen H, Kuitunen M, Suhonen J.
PMID: 28547393
Oecologia. 2001 Aug;128(4):488-491. doi: 10.1007/s004420100677. Epub 2001 Aug 01.

We examined to what extent breeding insectivorous treecreepers, Certhia familiaris, affect the abundance and the mean size of their prey population on the surface of tree trunks. In order to determine foraging pressure on tree trunks, we observed the...

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Jäntti A, Aho T, Hakkarainen H, et al. Prey depletion by the foraging of the Eurasian treecreeper, Certhia familiaris, on tree-trunk arthropods. Oecologia. 2001;128(4):488-491doi: 10.1007/s004420100677.
Jäntti, A., Aho, T., Hakkarainen, H., Kuitunen, M., & Suhonen, J. (2001). Prey depletion by the foraging of the Eurasian treecreeper, Certhia familiaris, on tree-trunk arthropods. Oecologia, 128(4), 488-491. https://doi.org/10.1007/s004420100677
Jäntti, Ari, et al. "Prey depletion by the foraging of the Eurasian treecreeper, Certhia familiaris, on tree-trunk arthropods." Oecologia vol. 128,4 (2001): 488-491. doi: https://doi.org/10.1007/s004420100677
Jäntti A, Aho T, Hakkarainen H, Kuitunen M, Suhonen J. Prey depletion by the foraging of the Eurasian treecreeper, Certhia familiaris, on tree-trunk arthropods. Oecologia. 2001 Aug;128(4):488-491. doi: 10.1007/s004420100677. Epub 2001 Aug 01. PMID: 28547393.
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Energy-efficient transmission strategies for CoMP downlink-overview, extension, and numerical comparison.

EURASIP journal on wireless communications and networking

Nguyen KG, Tervo O, Vu QD, Tran LN, Juntti M.
PMID: 30174684
EURASIP J Wirel Commun Netw. 2018;2018(1):207. doi: 10.1186/s13638-018-1214-2. Epub 2018 Aug 20.

This paper focuses on energy-efficient coordinated multi-point (CoMP) downlink in multi-antenna multi-cell wireless communications systems. We provide an overview of transmit beamforming designs for various energy efficiency (EE) metrics including maximizing the overall network EE, sum weighted EE, and...

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Nguyen KG, Tervo O, Vu QD, et al. Energy-efficient transmission strategies for CoMP downlink-overview, extension, and numerical comparison. EURASIP J Wirel Commun Netw. 2018;2018(1):207doi: 10.1186/s13638-018-1214-2.
Nguyen, K. G., Tervo, O., Vu, Q. D., Tran, L. N., & Juntti, M. (2018). Energy-efficient transmission strategies for CoMP downlink-overview, extension, and numerical comparison. EURASIP journal on wireless communications and networking, 2018(1), 207. https://doi.org/10.1186/s13638-018-1214-2
Nguyen, Kien-Giang, et al. "Energy-efficient transmission strategies for CoMP downlink-overview, extension, and numerical comparison." EURASIP journal on wireless communications and networking vol. 2018,1 (2018): 207. doi: https://doi.org/10.1186/s13638-018-1214-2
Nguyen KG, Tervo O, Vu QD, Tran LN, Juntti M. Energy-efficient transmission strategies for CoMP downlink-overview, extension, and numerical comparison. EURASIP J Wirel Commun Netw. 2018;2018(1):207. doi: 10.1186/s13638-018-1214-2. Epub 2018 Aug 20. PMID: 30174684; PMCID: PMC6105240.
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Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease.

Molecular genetics & genomic medicine

Laurell T, Nilsson D, Hofmeister W, Lindstrand A, Ahituv N, Vandermeer J, Amilon A, Annerén G, Arner M, Pettersson M, Jäntti N, Rosberg HE, Cattini PA, Nordenskjöld A, Mäkitie O, Grigelioniene G, Nordgren A.
PMID: 25333065
Mol Genet Genomic Med. 2014 Sep;2(5):402-11. doi: 10.1002/mgg3.81. Epub 2014 May 14.

Nonsense mutations in FGF16 have recently been linked to X-linked recessive hand malformations with fusion between the fourth and the fifth metacarpals and hypoplasia of the fifth digit (MF4; MIM#309630). The purpose of this study was to perform careful...

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Laurell T, Nilsson D, Hofmeister W, et al. Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease. Mol Genet Genomic Med. 2014;2(5):402-11doi: 10.1002/mgg3.81.
Laurell, T., Nilsson, D., Hofmeister, W., Lindstrand, A., Ahituv, N., Vandermeer, J., Amilon, A., Annerén, G., Arner, M., Pettersson, M., Jäntti, N., Rosberg, H. E., Cattini, P. A., Nordenskjöld, A., Mäkitie, O., Grigelioniene, G., & Nordgren, A. (2014). Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease. Molecular genetics & genomic medicine, 2(5), 402-11. https://doi.org/10.1002/mgg3.81
Laurell, Tobias, et al. "Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease." Molecular genetics & genomic medicine vol. 2,5 (2014): 402-11. doi: https://doi.org/10.1002/mgg3.81
Laurell T, Nilsson D, Hofmeister W, Lindstrand A, Ahituv N, Vandermeer J, Amilon A, Annerén G, Arner M, Pettersson M, Jäntti N, Rosberg HE, Cattini PA, Nordenskjöld A, Mäkitie O, Grigelioniene G, Nordgren A. Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease. Mol Genet Genomic Med. 2014 Sep;2(5):402-11. doi: 10.1002/mgg3.81. Epub 2014 May 14. PMID: 25333065; PMCID: PMC4190875.
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Showing 1 to 12 of 33 entries