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Showing 1 to 12 of 44 entries
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Clinical relevance of CHEK2 and NBN mutations in the macedonian population.

Balkan journal of medical genetics : BJMG

Kostovska IM, Jakimovska M, Kubelka-Sabit K, Karadjozov M, Arsovski A, Stojanovska L, Plaseska-Karanfilska D.
PMID: 26929905
Balkan J Med Genet. 2015 Dec 30;18(1):47-54. doi: 10.1515/bjmg-2015-0005. eCollection 2015 Jun.

Clinical importance of the most common CHEK2 (IVS2+1 G>A, 1100delC, I157T and del5395) and NBN (R215W and 657del5) gene mutations for breast cancer development in Macedonian breast cancer patients is unknown. We performed a case-control study including 300 Macedonian...

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Kostovska IM, Jakimovska M, Kubelka-Sabit K, et al. Clinical relevance of CHEK2 and NBN mutations in the macedonian population. Balkan J Med Genet. 2015;18(1):47-54doi: 10.1515/bjmg-2015-0005.
Kostovska, I. M., Jakimovska, M., Kubelka-Sabit, K., Karadjozov, M., Arsovski, A., Stojanovska, L., & Plaseska-Karanfilska, D. (2015). Clinical relevance of CHEK2 and NBN mutations in the macedonian population. Balkan journal of medical genetics : BJMG, 18(1), 47-54. https://doi.org/10.1515/bjmg-2015-0005
Kostovska, I Maleva, et al. "Clinical relevance of CHEK2 and NBN mutations in the macedonian population." Balkan journal of medical genetics : BJMG vol. 18,1 (2015): 47-54. doi: https://doi.org/10.1515/bjmg-2015-0005
Kostovska IM, Jakimovska M, Kubelka-Sabit K, Karadjozov M, Arsovski A, Stojanovska L, Plaseska-Karanfilska D. Clinical relevance of CHEK2 and NBN mutations in the macedonian population. Balkan J Med Genet. 2015 Dec 30;18(1):47-54. doi: 10.1515/bjmg-2015-0005. eCollection 2015 Jun. PMID: 26929905; PMCID: PMC4768825.
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The role of Epstein-Barr virus in multiple sclerosis: from molecular pathophysiology to .

Neural regeneration research

Guan Y, Jakimovski D, Ramanathan M, Weinstock-Guttman B, Zivadinov R.
PMID: 30539801
Neural Regen Res. 2019 Mar;14(3):373-386. doi: 10.4103/1673-5374.245462.

Multiple sclerosis (MS) is a disease of the central nervous system characterized by inflammation, demyelination, and neuronal damage. Environmental and genetic factors are associated with the risk of developing MS, but the exact cause still remains unidentified. Epstein-Barr virus...

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Guan Y, Jakimovski D, Ramanathan M, et al. The role of Epstein-Barr virus in multiple sclerosis: from molecular pathophysiology to . Neural Regen Res. 2019;14(3):373-386doi: 10.4103/1673-5374.245462.
Guan, Y., Jakimovski, D., Ramanathan, M., Weinstock-Guttman, B., & Zivadinov, R. (2019). The role of Epstein-Barr virus in multiple sclerosis: from molecular pathophysiology to . Neural regeneration research, 14(3), 373-386. https://doi.org/10.4103/1673-5374.245462
Guan, Yi, et al. "The role of Epstein-Barr virus in multiple sclerosis: from molecular pathophysiology to ." Neural regeneration research vol. 14,3 (2019): 373-386. doi: https://doi.org/10.4103/1673-5374.245462
Guan Y, Jakimovski D, Ramanathan M, Weinstock-Guttman B, Zivadinov R. The role of Epstein-Barr virus in multiple sclerosis: from molecular pathophysiology to . Neural Regen Res. 2019 Mar;14(3):373-386. doi: 10.4103/1673-5374.245462. PMID: 30539801; PMCID: PMC6334604.
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Infections, Vaccines and Autoimmunity: A Multiple Sclerosis Perspective.

Vaccines

Jakimovski D, Weinstock-Guttman B, Ramanathan M, Dwyer MG, Zivadinov R.
PMID: 32012815
Vaccines (Basel). 2020 Jan 28;8(1). doi: 10.3390/vaccines8010050.

No abstract available.

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Jakimovski D, Weinstock-Guttman B, Ramanathan M, et al. Infections, Vaccines and Autoimmunity: A Multiple Sclerosis Perspective. Vaccines (Basel). 2020;8(1)doi: 10.3390/vaccines8010050.
Jakimovski, D., Weinstock-Guttman, B., Ramanathan, M., Dwyer, M. G., & Zivadinov, R. (2020). Infections, Vaccines and Autoimmunity: A Multiple Sclerosis Perspective. Vaccines, 8(1), . https://doi.org/10.3390/vaccines8010050
Jakimovski, Dejan, et al. "Infections, Vaccines and Autoimmunity: A Multiple Sclerosis Perspective." Vaccines vol. 8,1 (2020). doi: https://doi.org/10.3390/vaccines8010050
Jakimovski D, Weinstock-Guttman B, Ramanathan M, Dwyer MG, Zivadinov R. Infections, Vaccines and Autoimmunity: A Multiple Sclerosis Perspective. Vaccines (Basel). 2020 Jan 28;8(1). doi: 10.3390/vaccines8010050. PMID: 32012815; PMCID: PMC7157658.
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Fractures and musculoskeletal ailments in persons 20+ years after a traumatic spinal cord injury in Norway.

Spinal cord series and cases

Jakimovska VM, Kostovski E, Biering-Sørensen F, Lidal IB.
PMID: 30131875
Spinal Cord Ser Cases. 2018 Aug 14;4:76. doi: 10.1038/s41394-018-0102-7. eCollection 2018.

STUDY DESIGN: Cross-sectional study.OBJECTIVES: To gain insights into fracture rate and musculoskeletal ailments among Norwegians with a spinal cord injury (SCI) acquired more than 20 years ago.SETTINGS: Sunnaas Hospital, Nesoddtangen, Norway.METHODS: 165 persons with SCI were interviewed in 2004-2005...

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Jakimovska VM, Kostovski E, Biering-Sørensen F, et al. Fractures and musculoskeletal ailments in persons 20+ years after a traumatic spinal cord injury in Norway. Spinal Cord Ser Cases. 2018;4:76doi: 10.1038/s41394-018-0102-7.
Jakimovska, V. M., Kostovski, E., Biering-Sørensen, F., & Lidal, I. B. (2018). Fractures and musculoskeletal ailments in persons 20+ years after a traumatic spinal cord injury in Norway. Spinal cord series and cases, 476. https://doi.org/10.1038/s41394-018-0102-7
Jakimovska, Vesna Miloshevska, et al. "Fractures and musculoskeletal ailments in persons 20+ years after a traumatic spinal cord injury in Norway." Spinal cord series and cases vol. 4 (2018): 76. doi: https://doi.org/10.1038/s41394-018-0102-7
Jakimovska VM, Kostovski E, Biering-Sørensen F, Lidal IB. Fractures and musculoskeletal ailments in persons 20+ years after a traumatic spinal cord injury in Norway. Spinal Cord Ser Cases. 2018 Aug 14;4:76. doi: 10.1038/s41394-018-0102-7. eCollection 2018. PMID: 30131875; PMCID: PMC6092425.
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MRI-based thalamic volumetry in multiple sclerosis using FSL-FIRST: Systematic assessment of common error modes.

Journal of neuroimaging : official journal of the American Society of Neuroimaging

Lyman C, Lee D, Ferrari H, Fuchs TA, Bergsland N, Jakimovski D, Weinstock-Guttmann B, Zivadinov R, Dwyer MG.
PMID: 34767684
J Neuroimaging. 2021 Nov 12; doi: 10.1111/jon.12947. Epub 2021 Nov 12.

BACKGROUND AND PURPOSE: FSL's FMRIB's Integrated Registration and Segmentation Tool (FSL-FIRST) is a widely used and well-validated tool. Automated thalamic segmentation is a common application and an important longitudinal measure for multiple sclerosis (MS). However, FSL-FIRST's algorithm is based...

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Lyman C, Lee D, Ferrari H, et al. MRI-based thalamic volumetry in multiple sclerosis using FSL-FIRST: Systematic assessment of common error modes. J Neuroimaging. 2021;doi: 10.1111/jon.12947.
Lyman, C., Lee, D., Ferrari, H., Fuchs, T. A., Bergsland, N., Jakimovski, D., Weinstock-Guttmann, B., Zivadinov, R., & Dwyer, M. G. (2021). MRI-based thalamic volumetry in multiple sclerosis using FSL-FIRST: Systematic assessment of common error modes. Journal of neuroimaging : official journal of the American Society of Neuroimaging, . https://doi.org/10.1111/jon.12947
Lyman, Cassondra, et al. "MRI-based thalamic volumetry in multiple sclerosis using FSL-FIRST: Systematic assessment of common error modes." Journal of neuroimaging : official journal of the American Society of Neuroimaging vol. (2021). doi: https://doi.org/10.1111/jon.12947
Lyman C, Lee D, Ferrari H, Fuchs TA, Bergsland N, Jakimovski D, Weinstock-Guttmann B, Zivadinov R, Dwyer MG. MRI-based thalamic volumetry in multiple sclerosis using FSL-FIRST: Systematic assessment of common error modes. J Neuroimaging. 2021 Nov 12; doi: 10.1111/jon.12947. Epub 2021 Nov 12. PMID: 34767684.
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Asymptomatic infection after BNT162b2 mRNA COVID-19 vaccination in multiple sclerosis patient.

Acta neurologica Belgica

Jakimovski D, Weinstock-Guttman B.
PMID: 34529258
Acta Neurol Belg. 2021 Sep 16; doi: 10.1007/s13760-021-01799-8. Epub 2021 Sep 16.

No abstract available.

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Jakimovski D, Weinstock-Guttman B. Asymptomatic infection after BNT162b2 mRNA COVID-19 vaccination in multiple sclerosis patient. Acta Neurol Belg. 2021;doi: 10.1007/s13760-021-01799-8.
Jakimovski, D., & Weinstock-Guttman, B. (2021). Asymptomatic infection after BNT162b2 mRNA COVID-19 vaccination in multiple sclerosis patient. Acta neurologica Belgica, . https://doi.org/10.1007/s13760-021-01799-8
Jakimovski, Dejan, and Weinstock-Guttman, Bianca. "Asymptomatic infection after BNT162b2 mRNA COVID-19 vaccination in multiple sclerosis patient." Acta neurologica Belgica vol. (2021). doi: https://doi.org/10.1007/s13760-021-01799-8
Jakimovski D, Weinstock-Guttman B. Asymptomatic infection after BNT162b2 mRNA COVID-19 vaccination in multiple sclerosis patient. Acta Neurol Belg. 2021 Sep 16; doi: 10.1007/s13760-021-01799-8. Epub 2021 Sep 16. PMID: 34529258; PMCID: PMC8444159.
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Functional network dynamics and decreased conscientiousness in multiple sclerosis.

Journal of neurology

Fuchs TA, Schoonheim MM, Broeders TAA, Hulst HE, Weinstock-Guttman B, Jakimovski D, Silver J, Zivadinov R, Geurts JJG, Dwyer MG, Benedict RHB.
PMID: 34713325
J Neurol. 2021 Oct 29; doi: 10.1007/s00415-021-10860-8. Epub 2021 Oct 29.

BACKGROUND: Conscientiousness is a personality trait that declines in people with multiple sclerosis (PwMS) and its decline predicts worse clinical outcomes. This study aims to investigate the neural underpinnings of lower Conscientiousness in PwMS by examining MRI anomalies in...

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Fuchs TA, Schoonheim MM, Broeders TAA, et al. Functional network dynamics and decreased conscientiousness in multiple sclerosis. J Neurol. 2021;doi: 10.1007/s00415-021-10860-8.
Fuchs, T. A., Schoonheim, M. M., Broeders, T. A. A., Hulst, H. E., Weinstock-Guttman, B., Jakimovski, D., Silver, J., Zivadinov, R., Geurts, J. J. G., Dwyer, M. G., & Benedict, R. H. B. (2021). Functional network dynamics and decreased conscientiousness in multiple sclerosis. Journal of neurology, . https://doi.org/10.1007/s00415-021-10860-8
Fuchs, Tom A, et al. "Functional network dynamics and decreased conscientiousness in multiple sclerosis." Journal of neurology vol. (2021). doi: https://doi.org/10.1007/s00415-021-10860-8
Fuchs TA, Schoonheim MM, Broeders TAA, Hulst HE, Weinstock-Guttman B, Jakimovski D, Silver J, Zivadinov R, Geurts JJG, Dwyer MG, Benedict RHB. Functional network dynamics and decreased conscientiousness in multiple sclerosis. J Neurol. 2021 Oct 29; doi: 10.1007/s00415-021-10860-8. Epub 2021 Oct 29. PMID: 34713325.
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Discontinuation of disease modifying therapies is associated with disability progression regardless of prior stable disease and age.

Multiple sclerosis and related disorders

Jakimovski D, Kavak KS, Vaughn CB, Goodman AD, Coyle PK, Krupp L, Gottesman M, Edwards KR, Lenihan M, Perel A, Zivadinov R, Weinstock-Guttman B.
PMID: 34915316
Mult Scler Relat Disord. 2021 Nov 16;57:103406. doi: 10.1016/j.msard.2021.103406. Epub 2021 Nov 16.

BACKGROUND: Multiple sclerosis (MS) patients with stable disease course might view continued treatment as unnecessary. However, guidelines regarding treatment discontinuation are currently lacking.OBJECTIVE: To assess the clinical course after treatment discontinuation in MS patients with long disease duration.METHODS: Patients...

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Jakimovski D, Kavak KS, Vaughn CB, et al. Discontinuation of disease modifying therapies is associated with disability progression regardless of prior stable disease and age. Mult Scler Relat Disord. 2021;57:103406doi: 10.1016/j.msard.2021.103406.
Jakimovski, D., Kavak, K. S., Vaughn, C. B., Goodman, A. D., Coyle, P. K., Krupp, L., Gottesman, M., Edwards, K. R., Lenihan, M., Perel, A., Zivadinov, R., Weinstock-Guttman, B. (2021). Discontinuation of disease modifying therapies is associated with disability progression regardless of prior stable disease and age. Multiple sclerosis and related disorders, 57103406. https://doi.org/10.1016/j.msard.2021.103406
Jakimovski, Dejan, et al. "Discontinuation of disease modifying therapies is associated with disability progression regardless of prior stable disease and age." Multiple sclerosis and related disorders vol. 57 (2021): 103406. doi: https://doi.org/10.1016/j.msard.2021.103406
Jakimovski D, Kavak KS, Vaughn CB, Goodman AD, Coyle PK, Krupp L, Gottesman M, Edwards KR, Lenihan M, Perel A, Zivadinov R, Weinstock-Guttman B. Discontinuation of disease modifying therapies is associated with disability progression regardless of prior stable disease and age. Mult Scler Relat Disord. 2021 Nov 16;57:103406. doi: 10.1016/j.msard.2021.103406. Epub 2021 Nov 16. PMID: 34915316.
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Cortical and Deep Gray Matter Perfusion Associations With Physical and Cognitive Performance in Multiple Sclerosis Patients.

Frontiers in neurology

Jakimovski D, Bergsland N, Dwyer MG, Traversone J, Hagemeier J, Fuchs TA, Ramasamy DP, Weinstock-Guttman B, Benedict RHB, Zivadinov R.
PMID: 32765407
Front Neurol. 2020 Jul 17;11:700. doi: 10.3389/fneur.2020.00700. eCollection 2020.

No abstract available.

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Jakimovski D, Bergsland N, Dwyer MG, et al. Cortical and Deep Gray Matter Perfusion Associations With Physical and Cognitive Performance in Multiple Sclerosis Patients. Front Neurol. 2020;11:700doi: 10.3389/fneur.2020.00700.
Jakimovski, D., Bergsland, N., Dwyer, M. G., Traversone, J., Hagemeier, J., Fuchs, T. A., Ramasamy, D. P., Weinstock-Guttman, B., Benedict, R. H. B., & Zivadinov, R. (2020). Cortical and Deep Gray Matter Perfusion Associations With Physical and Cognitive Performance in Multiple Sclerosis Patients. Frontiers in neurology, 11700. https://doi.org/10.3389/fneur.2020.00700
Jakimovski, Dejan, et al. "Cortical and Deep Gray Matter Perfusion Associations With Physical and Cognitive Performance in Multiple Sclerosis Patients." Frontiers in neurology vol. 11 (2020): 700. doi: https://doi.org/10.3389/fneur.2020.00700
Jakimovski D, Bergsland N, Dwyer MG, Traversone J, Hagemeier J, Fuchs TA, Ramasamy DP, Weinstock-Guttman B, Benedict RHB, Zivadinov R. Cortical and Deep Gray Matter Perfusion Associations With Physical and Cognitive Performance in Multiple Sclerosis Patients. Front Neurol. 2020 Jul 17;11:700. doi: 10.3389/fneur.2020.00700. eCollection 2020. PMID: 32765407; PMCID: PMC7380109.
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Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study.

NeuroImage. Clinical

Barnett M, Bergsland N, Weinstock-Guttman B, Butzkueven H, Kalincik T, Desmond P, Gaillard F, van Pesch V, Ozakbas S, Rojas JI, Boz C, Altintas A, Wang C, Dwyer MG, Yang S, Jakimovski D, Kyle K, Ramasamy DP, Zivadinov R.
PMID: 34469848
Neuroimage Clin. 2021;32:102802. doi: 10.1016/j.nicl.2021.102802. Epub 2021 Aug 24.

BACKGROUND: Methodological challenges limit the use of brain atrophy and lesion burden measures in the follow-up of multiple sclerosis (MS) patients on clinical routine datasets.OBJECTIVE: To determine the feasibility of T2-FLAIR-only measures of lateral ventricular volume (LVV) and salient...

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Barnett M, Bergsland N, Weinstock-Guttman B, et al. Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study. Neuroimage Clin. 2021;32:102802doi: 10.1016/j.nicl.2021.102802.
Barnett, M., Bergsland, N., Weinstock-Guttman, B., Butzkueven, H., Kalincik, T., Desmond, P., Gaillard, F., van Pesch, V., Ozakbas, S., Rojas, J. I., Boz, C., Altintas, A., Wang, C., Dwyer, M. G., Yang, S., Jakimovski, D., Kyle, K., Ramasamy, D. P., & Zivadinov, R. (2021). Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study. NeuroImage. Clinical, 32102802. https://doi.org/10.1016/j.nicl.2021.102802
Barnett, Michael, et al. "Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study." NeuroImage. Clinical vol. 32 (2021): 102802. doi: https://doi.org/10.1016/j.nicl.2021.102802
Barnett M, Bergsland N, Weinstock-Guttman B, Butzkueven H, Kalincik T, Desmond P, Gaillard F, van Pesch V, Ozakbas S, Rojas JI, Boz C, Altintas A, Wang C, Dwyer MG, Yang S, Jakimovski D, Kyle K, Ramasamy DP, Zivadinov R. Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study. Neuroimage Clin. 2021;32:102802. doi: 10.1016/j.nicl.2021.102802. Epub 2021 Aug 24. PMID: 34469848; PMCID: PMC8408519.
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Multiple Sclerosis in Children: Differential Diagnosis, Prognosis, and Disease-Modifying Treatment.

CNS drugs

Jakimovski D, Awan S, Eckert SP, Farooq O, Weinstock-Guttman B.
PMID: 34940954
CNS Drugs. 2021 Dec 23; doi: 10.1007/s40263-021-00887-w. Epub 2021 Dec 23.

Pediatric-onset multiple sclerosis (POMS) is a rare neuroinflammatory and neurodegenerative disease that has a significant impact on long-term physical and cognitive patient outcomes. A small percentage of multiple sclerosis (MS) diagnoses occur before the age of 18 years. Before...

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Jakimovski D, Awan S, Eckert SP, et al. Multiple Sclerosis in Children: Differential Diagnosis, Prognosis, and Disease-Modifying Treatment. CNS Drugs. 2021;doi: 10.1007/s40263-021-00887-w.
Jakimovski, D., Awan, S., Eckert, S. P., Farooq, O., & Weinstock-Guttman, B. (2021). Multiple Sclerosis in Children: Differential Diagnosis, Prognosis, and Disease-Modifying Treatment. CNS drugs, . https://doi.org/10.1007/s40263-021-00887-w
Jakimovski, Dejan, et al. "Multiple Sclerosis in Children: Differential Diagnosis, Prognosis, and Disease-Modifying Treatment." CNS drugs vol. (2021). doi: https://doi.org/10.1007/s40263-021-00887-w
Jakimovski D, Awan S, Eckert SP, Farooq O, Weinstock-Guttman B. Multiple Sclerosis in Children: Differential Diagnosis, Prognosis, and Disease-Modifying Treatment. CNS Drugs. 2021 Dec 23; doi: 10.1007/s40263-021-00887-w. Epub 2021 Dec 23. PMID: 34940954; PMCID: PMC8697541.
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Dimethyl Fumarate in the Treatment of Relapsing-Remitting Multiple Sclerosis: Patient Reported Outcomes and Perspectives.

Patient related outcome measures

Ozel O, Vaughn CB, Eckert SP, Jakimovski D, Lizarraga AA, Weinstock-Guttman B.
PMID: 31849554
Patient Relat Outcome Meas. 2019 Dec 11;10:373-384. doi: 10.2147/PROM.S168095. eCollection 2019.

Dimethyl fumarate (DMF) is a commonly prescribed oral medication for the treatment of relapsing forms of multiple sclerosis (MS) with a wide range of hypothesized downstream mechanisms of action. Randomized clinical trials have established its clinical efficacy by using...

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Ozel O, Vaughn CB, Eckert SP, et al. Dimethyl Fumarate in the Treatment of Relapsing-Remitting Multiple Sclerosis: Patient Reported Outcomes and Perspectives. Patient Relat Outcome Meas. 2019;10:373-384doi: 10.2147/PROM.S168095.
Ozel, O., Vaughn, C. B., Eckert, S. P., Jakimovski, D., Lizarraga, A. A., & Weinstock-Guttman, B. (2019). Dimethyl Fumarate in the Treatment of Relapsing-Remitting Multiple Sclerosis: Patient Reported Outcomes and Perspectives. Patient related outcome measures, 10373-384. https://doi.org/10.2147/PROM.S168095
Ozel, Osman, et al. "Dimethyl Fumarate in the Treatment of Relapsing-Remitting Multiple Sclerosis: Patient Reported Outcomes and Perspectives." Patient related outcome measures vol. 10 (2019): 373-384. doi: https://doi.org/10.2147/PROM.S168095
Ozel O, Vaughn CB, Eckert SP, Jakimovski D, Lizarraga AA, Weinstock-Guttman B. Dimethyl Fumarate in the Treatment of Relapsing-Remitting Multiple Sclerosis: Patient Reported Outcomes and Perspectives. Patient Relat Outcome Meas. 2019 Dec 11;10:373-384. doi: 10.2147/PROM.S168095. eCollection 2019. PMID: 31849554; PMCID: PMC6911812.
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Showing 1 to 12 of 44 entries