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Showing 1 to 12 of 65 entries
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Intravital

Mercier L, Böhm J, Fekonja N, Allio G, Lutz Y, Koch M, Goetz JG, Laporte J.
PMID: 28243519
Intravital. 2016 Apr 06;5(1):e1168553. doi: 10.1080/21659087.2016.1168553. eCollection 2016.

Skeletal muscle structure and function are altered in different myopathies. However, the understanding of the molecular and cellular mechanisms mainly rely on

Transformation of chlorinated phenolic compounds in the genusRhodococcus.

Microbial ecology

Häggblom MM, Janke D, Salkinoja-Salonen MS.
PMID: 24196130
Microb Ecol. 1989 Sep;18(2):147-59. doi: 10.1007/BF02030123.

The ability of strains of the genusRhodococcus to transform chlorinated phenolic compounds was studied. Noninduced cells of several strains ofRhodococcus, covering at least eight species, were found to attack mono-, di-, and trichlorophenols by hydroxylation at theortho position to...

Effect of the ligand shell composition on the dispersibility and transport of gold nanocrystals in near-critical solvents.

Langmuir : the ACS journal of surfaces and colloids

Fernandez CA, Bekhazi JG, Hoppes EM, Fryxell GE, Wang C, Bays JT, Warner MG, Wiacek RJ, Addleman RS.
PMID: 19256464
Langmuir. 2009 May 05;25(9):4900-6. doi: 10.1021/la804058x.

The development of more efficient and environmentally benign methods for the synthesis and manipulation of nanomaterials has been a major focus of research among the scientific community. Supercritical (ScFs) and near-critical fluids (NcFs) offer numerous advantages over conventional solvents...

Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis.

Arthritis research & therapy

Bode SF, Lehmberg K, Maul-Pavicic A, Vraetz T, Janka G, Stadt UZ, Ehl S.
PMID: 22682420
Arthritis Res Ther. 2012 Jun 08;14(3):213. doi: 10.1186/ar3843.

Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages secreting high amounts of inflammatory cytokines. It is a frequent manifestation in patients with predisposing genetic defects, but can...

Laminin α1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma.

Biology of the cell

Mammadova-Bach E, Rupp T, Spenlé C, Jivkov I, Shankaranarayanan P, Klein A, Pisarsky L, Méchine-Neuville A, Cremel G, Kedinger M, De Wever O, Ambartsumian N, Robine S, Pencreach E, Guenot D, Simon-Assmann P, Goetz JG, Orend G, Lefebvre O.
PMID: 29907957
Biol Cell. 2018 Jun 15; doi: 10.1111/boc.201800007. Epub 2018 Jun 15.

BACKGROUND INFORMATION: Tumor stroma remodeling is a key feature of malignant tumors and can promote cancer progression. Laminins are major constituents of basement membranes that physically separate the epithelium from the underlying stroma.RESULTS: By employing mouse models expressing high...

Fluorescent nanocarriers targeting VCAM-1 for early detection of senescent endothelial cells.

Nanomedicine : nanotechnology, biology, and medicine

Belcastro E, Rehman AU, Remila L, Park SH, Gong DS, Anton N, Auger C, Lefebvre O, Goetz JG, Collot M, Klymchenko AS, Vandamme TF, Schini-Kerth VB.
PMID: 33713860
Nanomedicine. 2021 Jun;34:102379. doi: 10.1016/j.nano.2021.102379. Epub 2021 Mar 11.

Endothelial senescence has been identified as an early event in the development of endothelial dysfunction, a hallmark of cardiovascular disease. This study developed theranostic nanocarriers (NC) decorated with VCAM-1 antibodies (NC-VCAM-1) in order to target cell surface VCAM-1, which...

Characterization of a recently synthesized microtubule-targeting compound that disrupts mitotic spindle poles in human cells.

Scientific reports

Jaunky DB, Larocque K, Husser MC, Liu JT, Forgione P, Piekny A.
PMID: 34880347
Sci Rep. 2021 Dec 08;11(1):23665. doi: 10.1038/s41598-021-03076-3.

We reveal the effects of a new microtubule-destabilizing compound in human cells. C75 has a core thienoisoquinoline scaffold with several functional groups amenable to modification. Previously we found that sub micromolar concentrations of C75 caused cytotoxicity. We also found...

Particulate matter emissions during field application of poultry manure - The influence of moisture content and treatment.

The Science of the total environment

Kabelitz T, Biniasch O, Ammon C, Nübel U, Thiel N, Janke D, Swaminathan S, Funk R, Münch S, Rösler U, Siller P, Amon B, Aarnink AJA, Amon T.
PMID: 34030313
Sci Total Environ. 2021 Aug 01;780:146652. doi: 10.1016/j.scitotenv.2021.146652. Epub 2021 Mar 20.

Along with industry and transportation, agriculture is one of the main sources of primary particulate matter (PM) emissions worldwide. Bioaerosol formation and PM release during livestock manure field application and the associated threats to environmental and human health are...

Visualizing Cancer.

Cancer cell

Krummel M, Hu K, de Vries EGE, Goetz JG, Passaro D, Subramaniam S, Misteli T, Skala M, Bravo-Cordero JJ, Sutcliffe JL.
PMID: 33321083
Cancer Cell. 2020 Dec 14;38(6):753-756. doi: 10.1016/j.ccell.2020.11.014.

Imaging has had a profound impact on our ability to understand and treat cancer. We invited some experts to discuss imaging approaches that can be used in various aspects of cancer research, from investigating the complexity and diversity of...

Author Correction: Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells.

Scientific reports

Follain G, Osmani N, Gensbittel V, Asokan N, Larnicol A, Mercier L, Garcia-Leon MJ, Busnelli I, Pichot A, Paul N, Carapito R, Bahram S, Lefebvre O, Goetz JG.
PMID: 34471187
Sci Rep. 2021 Sep 01;11(1):17765. doi: 10.1038/s41598-021-97172-z.

No abstract available.

[Ral-dependent tumor extracellular vesicles induce premetastatic niches in secondary organs].

Medecine sciences : M/S

Mary B, Ghoroghi S, Goetz JG, Hyenne V.
PMID: 34928214
Med Sci (Paris). 2021 Dec;37(12):1116-1118. doi: 10.1051/medsci/2021203. Epub 2021 Dec 20.

No abstract available.

Elimination of EVE protein by CALI in the short germ band insect Tribolium suggests a conserved pair-rule function for even skipped.

Mechanisms of development

Schröder R, Jay DG, Tautz D.
PMID: 10640722
Mech Dev. 2000 Feb 01;90(2):329. doi: 10.1016/s0925-4773(99)00286-5.

The question of the degree of evolutionary conservation of the pair-rule patterning mechanism known from Drosophila is still contentious. We have employed chromophore-assisted laser inactivation (CALI) to inactivate the function of the pair-rule gene even skipped (eve) in the...

Showing 1 to 12 of 65 entries