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Showing 1 to 12 of 121 entries
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Mechanotransduction in cancer.

Current opinion in chemical engineering

Chin L, Xia Y, Discher DE, Janmey PA.
PMID: 28344926
Curr Opin Chem Eng. 2016 Feb;11:77-84. doi: 10.1016/j.coche.2016.01.011. Epub 2016 Feb 16.

Tissue stiffness is tightly controlled under normal conditions, but changes with disease. In cancer, tumors often tend to be stiffer than the surrounding uninvolved tissue, yet the cells themselves soften. Within the past decade, and particularly in the last...

A faint type of supernova from a white dwarf with a helium-rich companion.

Nature

Perets HB, Gal-Yam A, Mazzali PA, Arnett D, Kagan D, Filippenko AV, Li W, Arcavi I, Cenko SB, Fox DB, Leonard DC, Moon DS, Sand DJ, Soderberg AM, Anderson JP, James PA, Foley RJ, Ganeshalingam M, Ofek EO, Bildsten L, Nelemans G, Shen KJ, Weinberg NN, Metzger BD, Piro AL, Quataert E, Kiewe M, Poznanski D.
PMID: 20485429
Nature. 2010 May 20;465(7296):322-5. doi: 10.1038/nature09056.

Supernovae are thought to arise from two different physical processes. The cores of massive, short-lived stars undergo gravitational core collapse and typically eject a few solar masses during their explosion. These are thought to appear as type Ib/c and...

High precision measurements of non-mass-dependent effects in nickel isotopes in meteoritic metal via multicollector ICPMS.

Analytical chemistry

Cook DL, Wadhwa M, Janney PE, Dauphas N, Clayton RN, Davis AM.
PMID: 17165842
Anal Chem. 2006 Dec 15;78(24):8477-84. doi: 10.1021/ac061285m.

We measured the Ni isotopic composition of metal from a variety of meteorite groups to search for variations in the 60Ni abundance from the decay of the short-lived nuclide 60Fe (t(1/2) = 1.49 My) and for possible nucleosynthetic effects...

The influence of exercise and BMI on injuries and illnesses in overweight and obese individuals: a randomized control trial.

The international journal of behavioral nutrition and physical activity

Janney CA, Jakicic JM.
PMID: 20145731
Int J Behav Nutr Phys Act. 2010 Jan 06;7:1. doi: 10.1186/1479-5868-7-1.

BACKGROUND: Medically treated injuries have been shown to increase with increasing body mass index (BMI). Information is lacking on the frequency and type of injuries and illnesses among overweight and obese adults who engage in regular physical activities as...

Elasticity of semiflexible biopolymer networks.

Physical review letters

Janmey PA, Käs J, MacKintosh FC.
PMID: 10059905
Phys Rev Lett. 1995 Dec 11;75(24):4425-4428. doi: 10.1103/PhysRevLett.75.4425.

No abstract available.

High-risk women's risk perception after receiving personalized polygenic breast cancer risk information.

Journal of community genetics

Forrest LE, Sawyer SD, Hallowell N, James PA, Young MA.
PMID: 30097836
J Community Genet. 2019 Apr;10(2):197-206. doi: 10.1007/s12687-018-0378-0. Epub 2018 Aug 10.

Evidence is accumulating of the clinical utility of single nucleotide polymorphisms to effectively stratify risk of breast cancer. Yet for this personalized polygenic information to be translated to clinical practice, consideration is needed about how this personalized risk information...

PET/CT imaging of the diapeutic alkylphosphocholine analog .

American journal of nuclear medicine and molecular imaging

Hall LT, Titz B, Robins HI, Bednarz BP, Perlman SB, Weichert JP, Kuo JS.
PMID: 28913154
Am J Nucl Med Mol Imaging. 2017 Sep 01;7(4):157-166. eCollection 2017.

CLR1404 is a cancer-selective alkyl phosphocholine (APC) analog that can be radiolabeled with

CTFS-ForestGEO: a worldwide network monitoring forests in an era of global change.

Global change biology

Anderson-Teixeira KJ, Davies SJ, Bennett AC, Gonzalez-Akre EB, Muller-Landau HC, Wright SJ, Abu Salim K, Almeyda Zambrano AM, Alonso A, Baltzer JL, Basset Y, Bourg NA, Broadbent EN, Brockelman WY, Bunyavejchewin S, Burslem DF, Butt N, Cao M, Cardenas D, Chuyong GB, Clay K, Cordell S, Dattaraja HS, Deng X, Detto M, Du X, Duque A, Erikson DL, Ewango CE, Fischer GA, Fletcher C, Foster RB, Giardina CP, Gilbert GS, Gunatilleke N, Gunatilleke S, Hao Z, Hargrove WW, Hart TB, Hau BC, He F, Hoffman FM, Howe RW, Hubbell SP, Inman-Narahari FM, Jansen PA, Jiang M, Johnson DJ, Kanzaki M, Kassim AR, Kenfack D, Kibet S, Kinnaird MF, Korte L, Kral K, Kumar J, Larson AJ, Li Y, Li X, Liu S, Lum SK, Lutz JA, Ma K, Maddalena DM, Makana JR, Malhi Y, Marthews T, Mat Serudin R, McMahon SM, McShea WJ, Memiaghe HR, Mi X, Mizuno T, Morecroft M, Myers JA, Novotny V, de Oliveira AA, Ong PS, Orwig DA, Ostertag R, den Ouden J, Parker GG, Phillips RP, Sack L, Sainge MN, Sang W, Sri-Ngernyuang K, Sukumar R, Sun IF, Sungpalee W, Suresh HS, Tan S, Thomas SC, Thomas DW, Thompson J, Turner BL, Uriarte M, Valencia R, Vallejo MI, Vicentini A, Vrška T, Wang X, Wang X, Weiblen G, Wolf A, Xu H, Yap S, Zimmerman J.
PMID: 25258024
Glob Chang Biol. 2015 Feb;21(2):528-49. doi: 10.1111/gcb.12712. Epub 2014 Sep 25.

Global change is impacting forests worldwide, threatening biodiversity and ecosystem services including climate regulation. Understanding how forests respond is critical to forest conservation and climate protection. This review describes an international network of 59 long-term forest dynamics research sites...

A novel method to make viscoelastic polyacrylamide gels for cell culture and traction force microscopy.

APL bioengineering

Charrier EE, Pogoda K, Li R, Park CY, Fredberg JJ, Janmey PA.
PMID: 32666015
APL Bioeng. 2020 Jul 02;4(3):036104. doi: 10.1063/5.0002750. eCollection 2020 Sep.

Polyacrylamide hydrogels are commonly used in cell biology, notably to cultivate cells on soft surfaces. Polyacrylamide gels are purely elastic and well adapted to cell culture as they are inert and can be conjugated with adhesion proteins. Here, we...

Correction to Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force.

ACS nano

Mandal K, Aroush DR, Graber ZT, Wu B, Park CY, Fredberg JJ, Guo W, Baumgart T, Janmey PA.
PMID: 30883087
ACS Nano. 2019 Apr 23;13(4):4854. doi: 10.1021/acsnano.9b01435. Epub 2019 Mar 18.

No abstract available.

Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting.

PloS one

Magee K, Marsh IR, Turek MM, Grudzinski J, Aluicio-Sarduy E, Engle JW, Kurzman ID, Zuleger CL, Oseid EA, Jaskowiak C, Albertini MR, Esbona K, Bednarz B, Sondel PM, Weichert JP, Morris ZS, Hernandez R, Vail DM.
PMID: 34383787
PLoS One. 2021 Aug 12;16(8):e0255798. doi: 10.1371/journal.pone.0255798. eCollection 2021.

RATIONALE: Murine syngeneic tumor models have revealed efficacious systemic antitumor responses following primary tumor in situ vaccination combined with targeted radionuclide therapy to secondary or metastatic tumors. Here we present studies on the safety and feasibility of this approach...

An updated quantitative model to classify missense variants in the TP53 gene: A novel multifactorial strategy.

Human mutation

Fortuno C, Pesaran T, Dolinsky J, Yussuf A, McGoldrick K, Tavtigian SV, Goldgar D, Spurdle AB, James PA.
PMID: 34273903
Hum Mutat. 2021 Oct;42(10):1351-1361. doi: 10.1002/humu.24264. Epub 2021 Aug 04.

Multigene panel testing has led to an increase in the number of variants of uncertain significance identified in the TP53 gene, associated with Li-Fraumeni syndrome. We previously developed a quantitative model for predicting the pathogenicity of P53 missense variants...

Showing 1 to 12 of 121 entries