Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 28 entries
Sorted by: Best Match Show Resources per page
Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.

Cell metabolism

Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM.
PMID: 28978428
Cell Metab. 2017 Oct 03;26(4):693. doi: 10.1016/j.cmet.2017.09.007.

No abstract available.

Cite
Kazak L, Chouchani ET, Lu GZ, et al. Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell Metab. 2017;26(4):693doi: 10.1016/j.cmet.2017.09.007.
Kazak, L., Chouchani, E. T., Lu, G. Z., Jedrychowski, M. P., Bare, C. J., Mina, A. I., Kumari, M., Zhang, S., Vuckovic, I., Laznik-Bogoslavski, D., Dzeja, P., Banks, A. S., Rosen, E. D., & Spiegelman, B. M. (2017). Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell metabolism, 26(4), 693. https://doi.org/10.1016/j.cmet.2017.09.007
Kazak, Lawrence, et al. "Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity." Cell metabolism vol. 26,4 (2017): 693. doi: https://doi.org/10.1016/j.cmet.2017.09.007
Kazak L, Chouchani ET, Lu GZ, Jedrychowski MP, Bare CJ, Mina AI, Kumari M, Zhang S, Vuckovic I, Laznik-Bogoslavski D, Dzeja P, Banks AS, Rosen ED, Spiegelman BM. Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Cell Metab. 2017 Oct 03;26(4):693. doi: 10.1016/j.cmet.2017.09.007. PMID: 28978428; PMCID: PMC5638127.
Copy Download .nbib Format: NLM
Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes.

Molecular metabolism

Jedrychowski MP, Liu L, Laflamme CJ, Karastergiou K, Meshulam T, Ding SY, Wu Y, Lee MJ, Gygi SP, Fried SK, Pilch PF.
PMID: 26629401
Mol Metab. 2015 Sep 18;4(11):758-70. doi: 10.1016/j.molmet.2015.09.002. eCollection 2015 Nov.

OBJECTIVE: Adipocytes are robust protein secretors, most notably of adipokines, hormone-like polypeptides, which act in an endocrine and paracrine fashion to affect numerous physiological processes such as energy balance and insulin sensitivity. To understand how such proteins are assembled...

Cite
Jedrychowski MP, Liu L, Laflamme CJ, et al. Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes. Mol Metab. 2015;4(11):758-70doi: 10.1016/j.molmet.2015.09.002.
Jedrychowski, M. P., Liu, L., Laflamme, C. J., Karastergiou, K., Meshulam, T., Ding, S. Y., Wu, Y., Lee, M. J., Gygi, S. P., Fried, S. K., & Pilch, P. F. (2015). Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes. Molecular metabolism, 4(11), 758-70. https://doi.org/10.1016/j.molmet.2015.09.002
Jedrychowski, Mark P, et al. "Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes." Molecular metabolism vol. 4,11 (2015): 758-70. doi: https://doi.org/10.1016/j.molmet.2015.09.002
Jedrychowski MP, Liu L, Laflamme CJ, Karastergiou K, Meshulam T, Ding SY, Wu Y, Lee MJ, Gygi SP, Fried SK, Pilch PF. Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes. Mol Metab. 2015 Sep 18;4(11):758-70. doi: 10.1016/j.molmet.2015.09.002. eCollection 2015 Nov. PMID: 26629401; PMCID: PMC4632174.
Copy Download .nbib Format: NLM
[A few remarks on the methodology of clinical controlled studies].

Polski tygodnik lekarski (Warsaw, Poland : 1960)

Jedrychowski W.
PMID: 7267455
Pol Tyg Lek. 1981 Mar 02;36(9):353-6.

No abstract available.

Cite
Jedrychowski W. Kilka uwag metodycznych na temat badań kliniczno-kontrolnych. [A few remarks on the methodology of clinical controlled studies]. Pol Tyg Lek. 1981;36(9):353-6
Jedrychowski, W. (1981). Kilka uwag metodycznych na temat badań kliniczno-kontrolnych. [A few remarks on the methodology of clinical controlled studies]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 36(9), 353-6.
Jedrychowski, W. "Kilka uwag metodycznych na temat badań kliniczno-kontrolnych." [A few remarks on the methodology of clinical controlled studies]. Polski tygodnik lekarski (Warsaw, Poland : 1960) vol. 36,9 (1981): 353-6.
Jedrychowski W. Kilka uwag metodycznych na temat badań kliniczno-kontrolnych. [A few remarks on the methodology of clinical controlled studies]. Pol Tyg Lek. 1981 Mar 02;36(9):353-6. Polish. PMID: 7267455.
Copy Download .nbib Format: NLM
Excessive weight and hypertension in the elderly - the results of the community study.

Archives of gerontology and geriatrics

Jedrychowski W, Mroz E, Bojanczyk M, Jedrychowska I.
PMID: 15374436
Arch Gerontol Geriatr. 1991 Jul-Aug;13(1):61-9. doi: 10.1016/0167-4943(91)90016-j.

The purpose of the study was to examine the relationship between excessive weight and systolic-diastolic and isolated systolic hypertension in the elderly. The sample covered 631 men and 1269 women of age 65-84 who took part in the screening...

Cite
Jedrychowski W, Mroz E, Bojanczyk M, et al. Excessive weight and hypertension in the elderly - the results of the community study. Arch Gerontol Geriatr. 1991;13(1):61-9doi: 10.1016/0167-4943(91)90016-j.
Jedrychowski, W., Mroz, E., Bojanczyk, M., & Jedrychowska, I. (1991). Excessive weight and hypertension in the elderly - the results of the community study. Archives of gerontology and geriatrics, 13(1), 61-9. https://doi.org/10.1016/0167-4943(91)90016-j
Jedrychowski, W, et al. "Excessive weight and hypertension in the elderly - the results of the community study." Archives of gerontology and geriatrics vol. 13,1 (1991): 61-9. doi: https://doi.org/10.1016/0167-4943(91)90016-j
Jedrychowski W, Mroz E, Bojanczyk M, Jedrychowska I. Excessive weight and hypertension in the elderly - the results of the community study. Arch Gerontol Geriatr. 1991 Jul-Aug;13(1):61-9. doi: 10.1016/0167-4943(91)90016-j. PMID: 15374436.
Copy Download .nbib Format: NLM
Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy.

Frontiers in neuroscience

Muraoka S, Jedrychowski MP, Tatebe H, DeLeo AM, Ikezu S, Tokuda T, Gygi SP, Stern RA, Ikezu T.
PMID: 31649498
Front Neurosci. 2019 Oct 09;13:1059. doi: 10.3389/fnins.2019.01059. eCollection 2019.

Chronic Traumatic Encephalopathy (CTE) is a tauopathy that affects individuals with a history of repetitive mild traumatic brain injury, such as American football players. Initial neuropathologic changes in CTE include perivascular deposition of phosphorylated microtubule-associated protein tau (p-tau) neurofibrillary...

Cite
Muraoka S, Jedrychowski MP, Tatebe H, et al. Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy. Front Neurosci. 2019;13:1059doi: 10.3389/fnins.2019.01059.
Muraoka, S., Jedrychowski, M. P., Tatebe, H., DeLeo, A. M., Ikezu, S., Tokuda, T., Gygi, S. P., Stern, R. A., & Ikezu, T. (2019). Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy. Frontiers in neuroscience, 131059. https://doi.org/10.3389/fnins.2019.01059
Muraoka, Satoshi, et al. "Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy." Frontiers in neuroscience vol. 13 (2019): 1059. doi: https://doi.org/10.3389/fnins.2019.01059
Muraoka S, Jedrychowski MP, Tatebe H, DeLeo AM, Ikezu S, Tokuda T, Gygi SP, Stern RA, Ikezu T. Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy. Front Neurosci. 2019 Oct 09;13:1059. doi: 10.3389/fnins.2019.01059. eCollection 2019. PMID: 31649498; PMCID: PMC6794346.
Copy Download .nbib Format: NLM
Signalling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages.

The Journal of biological chemistry

Williams NC, Ryan DG, Costa ASH, Mills EL, Jedrychowski MP, Cloonan SM, Frezza C, O'Neill LA.
PMID: 34929172
J Biol Chem. 2021 Dec 17;101501. doi: 10.1016/j.jbc.2021.101501. Epub 2021 Dec 17.

Activated macrophages undergo metabolic reprogramming which not only supports their energetic demands but also allows for the production of specific metabolites that function as signalling molecules. Several Krebs cycle, or Krebs cycle-derived metabolites, including succinate, α-ketoglutarate and itaconate, have...

Cite
Williams NC, Ryan DG, Costa ASH, et al. Signalling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages. J Biol Chem. 2021;101501doi: 10.1016/j.jbc.2021.101501.
Williams, N. C., Ryan, D. G., Costa, A. S. H., Mills, E. L., Jedrychowski, M. P., Cloonan, S. M., Frezza, C., & O'Neill, L. A. (2021). Signalling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages. The Journal of biological chemistry, 101501. https://doi.org/10.1016/j.jbc.2021.101501
Williams, Niamh C, et al. "Signalling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages." The Journal of biological chemistry vol. (2021): 101501. doi: https://doi.org/10.1016/j.jbc.2021.101501
Williams NC, Ryan DG, Costa ASH, Mills EL, Jedrychowski MP, Cloonan SM, Frezza C, O'Neill LA. Signalling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages. J Biol Chem. 2021 Dec 17;101501. doi: 10.1016/j.jbc.2021.101501. Epub 2021 Dec 17. PMID: 34929172.
Copy Download .nbib Format: NLM
A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation.

Cell metabolism

Latorre-Muro P, O'Malley KE, Bennett CF, Perry EA, Balsa E, Tavares CDJ, Jedrychowski M, Gygi SP, Puigserver P.
PMID: 33592173
Cell Metab. 2021 Mar 02;33(3):598-614.e7. doi: 10.1016/j.cmet.2021.01.013. Epub 2021 Feb 15.

The architecture of cristae provides a spatial mitochondrial organization that contains functional respiratory complexes. Several protein components including OPA1 and MICOS complex subunits organize cristae structure, but upstream regulatory mechanisms are largely unknown. Here, in vivo and in vitro...

Cite
Latorre-Muro P, O'Malley KE, Bennett CF, et al. A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation. Cell Metab. 2021;33(3):598-614.e7doi: 10.1016/j.cmet.2021.01.013.
Latorre-Muro, P., O'Malley, K. E., Bennett, C. F., Perry, E. A., Balsa, E., Tavares, C. D. J., Jedrychowski, M., Gygi, S. P., & Puigserver, P. (2021). A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation. Cell metabolism, 33(3), 598-614.e7. https://doi.org/10.1016/j.cmet.2021.01.013
Latorre-Muro, Pedro, et al. "A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation." Cell metabolism vol. 33,3 (2021): 598-614.e7. doi: https://doi.org/10.1016/j.cmet.2021.01.013
Latorre-Muro P, O'Malley KE, Bennett CF, Perry EA, Balsa E, Tavares CDJ, Jedrychowski M, Gygi SP, Puigserver P. A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation. Cell Metab. 2021 Mar 02;33(3):598-614.e7. doi: 10.1016/j.cmet.2021.01.013. Epub 2021 Feb 15. PMID: 33592173; PMCID: PMC7962155.
Copy Download .nbib Format: NLM
Functional status of the lower extremities in elderly males. A community study.

Archives of gerontology and geriatrics

Jedrychowski W, Mroz E, Tobiasz-Adamczyk B, Jedrychowska I.
PMID: 15374507
Arch Gerontol Geriatr. 1990 Mar-Apr;10(2):117-22. doi: 10.1016/0167-4943(90)90012-u.

The purpose of this study was to evaluate the functional status of the lower extremities (FSL) of elderly males from the community and to compare it with the self-assessment of health status (SHS) and ventilatory lung function based on...

Cite
Jedrychowski W, Mroz E, Tobiasz-Adamczyk B, et al. Functional status of the lower extremities in elderly males. A community study. Arch Gerontol Geriatr. 1990;10(2):117-22doi: 10.1016/0167-4943(90)90012-u.
Jedrychowski, W., Mroz, E., Tobiasz-Adamczyk, B., & Jedrychowska, I. (1990). Functional status of the lower extremities in elderly males. A community study. Archives of gerontology and geriatrics, 10(2), 117-22. https://doi.org/10.1016/0167-4943(90)90012-u
Jedrychowski, W, et al. "Functional status of the lower extremities in elderly males. A community study." Archives of gerontology and geriatrics vol. 10,2 (1990): 117-22. doi: https://doi.org/10.1016/0167-4943(90)90012-u
Jedrychowski W, Mroz E, Tobiasz-Adamczyk B, Jedrychowska I. Functional status of the lower extremities in elderly males. A community study. Arch Gerontol Geriatr. 1990 Mar-Apr;10(2):117-22. doi: 10.1016/0167-4943(90)90012-u. PMID: 15374507.
Copy Download .nbib Format: NLM
Effects of smoking and longevity of parents on lung function in the apparently healty elderly.

Archives of gerontology and geriatrics

Jedrychowski W.
PMID: 15374518
Arch Gerontol Geriatr. 1990 Jan-Feb;10(1):19-26. doi: 10.1016/0167-4943(90)90040-d.

The assessment of the effects of smoking and longevity of parents on lung function in the elderly was carried out in a large sample of men (559) and women (1073) in Cracow. The lung function indices decreased linearly with...

Cite
Jedrychowski W. Effects of smoking and longevity of parents on lung function in the apparently healty elderly. Arch Gerontol Geriatr. 1990;10(1):19-26doi: 10.1016/0167-4943(90)90040-d.
Jedrychowski, W. (1990). Effects of smoking and longevity of parents on lung function in the apparently healty elderly. Archives of gerontology and geriatrics, 10(1), 19-26. https://doi.org/10.1016/0167-4943(90)90040-d
Jedrychowski, W. "Effects of smoking and longevity of parents on lung function in the apparently healty elderly." Archives of gerontology and geriatrics vol. 10,1 (1990): 19-26. doi: https://doi.org/10.1016/0167-4943(90)90040-d
Jedrychowski W. Effects of smoking and longevity of parents on lung function in the apparently healty elderly. Arch Gerontol Geriatr. 1990 Jan-Feb;10(1):19-26. doi: 10.1016/0167-4943(90)90040-d. PMID: 15374518.
Copy Download .nbib Format: NLM
Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1.

Nature

Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM.
PMID: 27281219
Nature. 2016 Aug 18;536(7616):360. doi: 10.1038/nature18279. Epub 2016 May 18.

No abstract available.

Cite
Chouchani ET, Kazak L, Jedrychowski MP, et al. Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature. 2016;536(7616):360doi: 10.1038/nature18279.
Chouchani, E. T., Kazak, L., Jedrychowski, M. P., Lu, G. Z., Erickson, B. K., Szpyt, J., Pierce, K. A., Laznik-Bogoslavski, D., Vetrivelan, R., Clish, C. B., Robinson, A. J., Gygi, S. P., & Spiegelman, B. M. (2016). Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature, 536(7616), 360. https://doi.org/10.1038/nature18279
Chouchani, Edward T, et al. "Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1." Nature vol. 536,7616 (2016): 360. doi: https://doi.org/10.1038/nature18279
Chouchani ET, Kazak L, Jedrychowski MP, Lu GZ, Erickson BK, Szpyt J, Pierce KA, Laznik-Bogoslavski D, Vetrivelan R, Clish CB, Robinson AJ, Gygi SP, Spiegelman BM. Corrigendum: Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature. 2016 Aug 18;536(7616):360. doi: 10.1038/nature18279. Epub 2016 May 18. PMID: 27281219.
Copy Download .nbib Format: NLM
Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation.

Cell metabolism

Mills EL, Harmon C, Jedrychowski MP, Xiao H, Gruszczyk AV, Bradshaw GA, Tran N, Garrity R, Laznik-Bogoslavski D, Szpyt J, Prendeville H, Lynch L, Murphy MP, Gygi SP, Spiegelman BM, Chouchani ET.
PMID: 34861155
Cell Metab. 2022 Jan 04;34(1):140-157.e8. doi: 10.1016/j.cmet.2021.11.003. Epub 2021 Dec 02.

Uncoupling protein 1 (UCP1) is a major regulator of brown and beige adipocyte energy expenditure and metabolic homeostasis. However, the widely employed UCP1 loss-of-function model has recently been shown to have a severe deficiency in the entire electron transport...

Cite
Mills EL, Harmon C, Jedrychowski MP, et al. Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation. Cell Metab. 2021;34(1):140-157.e8doi: 10.1016/j.cmet.2021.11.003.
Mills, E. L., Harmon, C., Jedrychowski, M. P., Xiao, H., Gruszczyk, A. V., Bradshaw, G. A., Tran, N., Garrity, R., Laznik-Bogoslavski, D., Szpyt, J., Prendeville, H., Lynch, L., Murphy, M. P., Gygi, S. P., Spiegelman, B. M., & Chouchani, E. T. (2022). Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation. Cell metabolism, 34(1), 140-157.e8. https://doi.org/10.1016/j.cmet.2021.11.003
Mills, Evanna L, et al. "Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation." Cell metabolism vol. 34,1 (2022): 140-157.e8. doi: https://doi.org/10.1016/j.cmet.2021.11.003
Mills EL, Harmon C, Jedrychowski MP, Xiao H, Gruszczyk AV, Bradshaw GA, Tran N, Garrity R, Laznik-Bogoslavski D, Szpyt J, Prendeville H, Lynch L, Murphy MP, Gygi SP, Spiegelman BM, Chouchani ET. Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation. Cell Metab. 2022 Jan 04;34(1):140-157.e8. doi: 10.1016/j.cmet.2021.11.003. Epub 2021 Dec 02. PMID: 34861155; PMCID: PMC8732317.
Copy Download .nbib Format: NLM
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

Cell

Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM.
PMID: 31299203
Cell. 2019 Jul 11;178(2):507-508. doi: 10.1016/j.cell.2019.06.028.

No abstract available.

Cite
Kim H, Wrann CD, Jedrychowski M, et al. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell. 2019;178(2):507-508doi: 10.1016/j.cell.2019.06.028.
Kim, H., Wrann, C. D., Jedrychowski, M., Vidoni, S., Kitase, Y., Nagano, K., Zhou, C., Chou, J., Parkman, V. A., Novick, S. J., Strutzenberg, T. S., Pascal, B. D., Le, P. T., Brooks, D. J., Roche, A. M., Gerber, K. K., Mattheis, L., Chen, W., Tu, H., Bouxsein, M. L., Griffin, P. R., Baron, R., Rosen, C. J., Bonewald, L. F., & Spiegelman, B. M. (2019). Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell, 178(2), 507-508. https://doi.org/10.1016/j.cell.2019.06.028
Kim, Hyeonwoo, et al. "Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors." Cell vol. 178,2 (2019): 507-508. doi: https://doi.org/10.1016/j.cell.2019.06.028
Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell. 2019 Jul 11;178(2):507-508. doi: 10.1016/j.cell.2019.06.028. PMID: 31299203; PMCID: PMC6707723.
Copy Download .nbib Format: NLM
Showing 1 to 12 of 28 entries