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Showing 1 to 12 of 66 entries
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Management of adult choledochal cysts--a 15-year experience.

HPB : the official journal of the International Hepato Pancreato Biliary Association

Jesudason SR, Jesudason MR, Mukha RP, Vyas FL, Govil S, Muthusami JC.
PMID: 18333140
HPB (Oxford). 2006;8(4):299-305. doi: 10.1080/13651820500466715.

BACKGROUND: Choledochal cyst, a common surgical problem of childhood, can have a delayed presentation in adults. The clinical course in adults differs from that in children because of a higher incidence of associated hepatobiliary pathology.METHODS: The clinical data of...

Heterogeneously catalyzed asymmetric hydrogenation of C=C bonds directed by surface-tethered chiral modifiers.

Journal of the American Chemical Society

Watson DJ, Jesudason RJ, Beaumont SK, Kyriakou G, Burton JW, Lambert RM.
PMID: 19754049
J Am Chem Soc. 2009 Oct 14;131(40):14584-9. doi: 10.1021/ja906356g.

Asymmetric hydrogenation of C=C bonds is of the highest importance in organic synthesis, and such reactions are currently carried out with organometallic homogeneous catalysts. Achieving heterogeneous metal-catalyzed hydrogenation, a highly desirable goal, necessitates forcing the crucial enantiodifferentiating step to...

An unusual cause of subarachnoid haemorrhage in a patient with newly diagnosed neurofibromatosis: a case report.

Cases journal

Weerasinghe C, Jesudason P, Peckham D.
PMID: 19918425
Cases J. 2009 Aug 11;2:8399. doi: 10.4076/1757-1626-2-8399.

INTRODUCTION: In this report we discuss an unusual cause of subarachnoid haemorrhage in association with neurofibromatosis.CASE PRESENTATION: A previously fit 55-year-old man developed sudden onset headache with loss of consciousness. He was comatose on admission with no focal neurological...

LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy.

Frontiers in neuroscience

Fitch TE, Benvenga MJ, Jesudason CD, Zink C, Vandergriff AB, Menezes MM, Schober DA, Rorick-Kehn LM.
PMID: 24478625
Front Neurosci. 2014 Jan 28;8:5. doi: 10.3389/fnins.2014.00005. eCollection 2014.

We describe a novel, potent and selective orexin-2 (OX2)/hypocretin-2 receptor antagonist with in vivo activity in an animal model predictive of antidepressant-like efficacy. N-biphenyl-2-yl-4-fluoro-N-(1H-imidazol-2-ylmethyl) benzenesulfonamide HCl (LSN2424100) binds with high affinity to recombinant human OX2 receptors (Ki = 4.5...

Achieving universal eye health coverage: planning and human resource lessons from trachoma.

Community eye health

Courtright P, Lewallen S, Jesudason T.
PMID: 30220811
Community Eye Health. 2018;31(102):54.

No abstract available.

Type VI Choledochal Cysts-Case Report and Review of Literature.

Surgery journal (New York, N.Y.)

Amarjothi JMV, Ramasamy V, Jesudasan J, NaganathBabu OL.
PMID: 31453343
Surg J (N Y). 2019 Aug 23;5(3):e82-e86. doi: 10.1055/s-0039-1693652. eCollection 2019 Jul.

Choledochal cysts (CDC), are rare congenital dilations involving the extra hepatic biliary apparatus with or without dilation of the intrahepatic bile ducts. They are conventionally classified into five types. A new type, type VI, causing dilation of the cystic...

SERCA directs cell migration and branching across species and germ layers.

Biology open

Bower DV, Lansdale N, Navarro S, Truong TV, Bower DJ, Featherstone NC, Connell MG, Al Alam D, Frey MR, Trinh LA, Fernandez GE, Warburton D, Fraser SE, Bennett D, Jesudason EC.
PMID: 28821490
Biol Open. 2017 Oct 15;6(10):1458-1471. doi: 10.1242/bio.026039.

Branching morphogenesis underlies organogenesis in vertebrates and invertebrates, yet is incompletely understood. Here, we show that the sarco-endoplasmic reticulum Ca

Denosumab-Induced Severe Hypocalcaemia in Chronic Kidney Disease.

Case reports in nephrology

Jalleh R, Basu G, Le Leu R, Jesudason S.
PMID: 30519493
Case Rep Nephrol. 2018 Nov 04;2018:7384763. doi: 10.1155/2018/7384763. eCollection 2018.

BACKGROUND: Hypocalcaemia is increasingly recognized as a complication of denosumab use in Chronic Kidney Disease (CKD) patients with osteoporosis. Despite Therapeutic Goods Administration (TGA) notifications in 2013, we have subsequently encountered several cases of denosumab-induced hypocalcaemia, raising concern about...

Management of Autosomal Dominant Polycystic Kidney Disease (ADPKD) During Pregnancy: Risks and Challenges.

International journal of women's health

McBride L, Wilkinson C, Jesudason S.
PMID: 32547249
Int J Womens Health. 2020 May 25;12:409-422. doi: 10.2147/IJWH.S204997. eCollection 2020.

Autosomal dominant polycystic kidney disease (ADPKD) affects up to 1 in 1000 people. The disease is characterized by the progressive development of cysts throughout the renal parenchyma due to inherited pathogenic variants in genes including

Risperidone for successful treatment of postictal psychosis refractory to olanzapine.

Proceedings (Baylor University. Medical Center)

Park AK, Jesudasen SJ, Olson KR.
PMID: 33678978
Proc (Bayl Univ Med Cent). 2021 Jan 20;34(2):318-320. doi: 10.1080/08998280.2020.1860450.

Postictal psychosis (PIP) in patients with epilepsy is often mistaken for other primary psychiatric disorders. Depending on its severity, PIP often prompts empiric treatment with atypical antipsychotics, which are balanced against the risk of lowered seizure thresholds. Here we...

Combination of a Beta adrenoceptor modulator and a norepinephrine-serotonin uptake inhibitor for the treatment of obesity.

ACS medicinal chemistry letters

Jesudason CD, Baker JE, Bryant RD, Fisher JW, O'Farrell LS, Gaich GA, He MM, Kahl SD, Kriauciunas AV, Heiman ML, Peters MA, Rito CJ, Satterwhite JH, Tinsley FC, Trankle WG, Shuker AJ.
PMID: 24900353
ACS Med Chem Lett. 2011 May 23;2(8):583-6. doi: 10.1021/ml200071k. eCollection 2011 Aug 11.

We report the novel combination of a selective beta adrenoceptor modulator and a norepinephrine-serotonin uptake inhibitor (sibutramine) with potential for the treatment of obesity. The synthesis and characterization of 6-[4-[2-[[(2S)-3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carboxamide (LY377604), a human β3-adrenergic receptor agonist and β1- and...

Making gains sustainable: partnering with WASH to stop the transmission of trachoma.

Community eye health

Wohlgemuth L, Hamilton H, Jesudason T.
PMID: 29915467
Community Eye Health. 2018;31(101):24.

No abstract available.

Showing 1 to 12 of 66 entries