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Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus.

Toxicon : official journal of the International Society on Toxinology

Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, Zamudio F, Orozco-Gutiérrez G, Oceguera-Contreras E, Enríquez-Vara JN, Vazquez-Vuelvas OF, García-Villalvazo PE, Valdez-Velázquez LL.
PMID: 34973996
Toxicon. 2021 Dec 30; doi: 10.1016/j.toxicon.2021.12.015. Epub 2021 Dec 30.

The venom of scorpions is a mixture of components that constitute a source of bioactive molecules. The venom of the scorpion Centruroides tecomanus contains peptides toxic to insects, however, to date no toxin responsible for this activity has yet...

Cite
Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, et al. Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon. 2021;doi: 10.1016/j.toxicon.2021.12.015.
Bermúdez-Guzmán, M. J., Jiménez-Vargas, J. M., Possani, L. D., Zamudio, F., Orozco-Gutiérrez, G., Oceguera-Contreras, E., Enríquez-Vara, J. N., Vazquez-Vuelvas, O. F., García-Villalvazo, P. E., & Valdez-Velázquez, L. L. (2021). Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon : official journal of the International Society on Toxinology, . https://doi.org/10.1016/j.toxicon.2021.12.015
Bermúdez-Guzmán, M J, et al. "Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus." Toxicon : official journal of the International Society on Toxinology vol. (2021). doi: https://doi.org/10.1016/j.toxicon.2021.12.015
Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, Zamudio F, Orozco-Gutiérrez G, Oceguera-Contreras E, Enríquez-Vara JN, Vazquez-Vuelvas OF, García-Villalvazo PE, Valdez-Velázquez LL. Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon. 2021 Dec 30; doi: 10.1016/j.toxicon.2021.12.015. Epub 2021 Dec 30. PMID: 34973996.
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Corrigendum to "Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms" [Toxicon 128 (2017) 5-14].

Toxicon : official journal of the International Society on Toxinology

Jiménez-Vargas JM, Quintero-Hernández V, Gonzalez-Morales L, Ortiz E, Possani LD.
PMID: 28284065
Toxicon. 2017 May;130:126. doi: 10.1016/j.toxicon.2017.03.002. Epub 2017 Mar 08.

No abstract available.

Cite
Jiménez-Vargas JM, Quintero-Hernández V, Gonzalez-Morales L, et al. Corrigendum to "Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms" [Toxicon 128 (2017) 5-14]. Toxicon. 2017;130:126doi: 10.1016/j.toxicon.2017.03.002.
Jiménez-Vargas, J. M., Quintero-Hernández, V., Gonzalez-Morales, L., Ortiz, E., & Possani, L. D. (2017). Corrigendum to "Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms" [Toxicon 128 (2017) 5-14]. Toxicon : official journal of the International Society on Toxinology, 130126. https://doi.org/10.1016/j.toxicon.2017.03.002
Jiménez-Vargas, J M, et al. "Corrigendum to "Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms" [Toxicon 128 (2017) 5-14]." Toxicon : official journal of the International Society on Toxinology vol. 130 (2017): 126. doi: https://doi.org/10.1016/j.toxicon.2017.03.002
Jiménez-Vargas JM, Quintero-Hernández V, Gonzalez-Morales L, Ortiz E, Possani LD. Corrigendum to "Design and expression of recombinant toxins from Mexican scorpions of the genus Centruroides for production of antivenoms" [Toxicon 128 (2017) 5-14]. Toxicon. 2017 May;130:126. doi: 10.1016/j.toxicon.2017.03.002. Epub 2017 Mar 08. PMID: 28284065.
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[About public health communication strategies and campaigns: what do you know about 2019-nCoV?].

Revista espanola de salud publica

Bilbatua Andrés J, Mudaber J, Jiménez-Vargas D, Arrieta Angulo B.
PMID: 32452469
Rev Esp Salud Publica. 2020 May 26;94:e1-e2.

No abstract available.

Cite
Bilbatua Andrés J, Mudaber J, Jiménez-Vargas D, et al. Sobre las Estrategias y Campañas de Comunicación en Salud Pública: ¿qué sabes del 2019-nCoV?. [About public health communication strategies and campaigns: what do you know about 2019-nCoV?]. Rev Esp Salud Publica. 2020;94:e1-e2
Bilbatua Andrés, J., Mudaber, J., Jiménez-Vargas, D., & Arrieta Angulo, B. (2020). Sobre las Estrategias y Campañas de Comunicación en Salud Pública: ¿qué sabes del 2019-nCoV?. [About public health communication strategies and campaigns: what do you know about 2019-nCoV?]. Revista espanola de salud publica, 94e1-e2.
Bilbatua Andrés, Jon, et al. "Sobre las Estrategias y Campañas de Comunicación en Salud Pública: ¿qué sabes del 2019-nCoV?." [About public health communication strategies and campaigns: what do you know about 2019-nCoV?]. Revista espanola de salud publica vol. 94 (2020): e1-e2.
Bilbatua Andrés J, Mudaber J, Jiménez-Vargas D, Arrieta Angulo B. Sobre las Estrategias y Campañas de Comunicación en Salud Pública: ¿qué sabes del 2019-nCoV?. [About public health communication strategies and campaigns: what do you know about 2019-nCoV?]. Rev Esp Salud Publica. 2020 May 26;94:e1-e2. Spanish. PMID: 32452469.
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Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus.

Toxicon : official journal of the International Society on Toxinology

Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, Zamudio F, Orozco-Gutiérrez G, Oceguera-Contreras E, Enríquez-Vara JN, Vazquez-Vuelvas OF, García-Villalvazo PE, Valdez-Velázquez LL.
PMID: 34973996
Toxicon. 2022 Jan 30;206:90-102. doi: 10.1016/j.toxicon.2021.12.015. Epub 2021 Dec 31.

The venom of scorpions is a mixture of components that constitute a source of bioactive molecules. The venom of the scorpion Centruroides tecomanus contains peptides toxic to insects, however, to date no toxin responsible for this activity has yet...

Cite
Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, et al. Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon. 2021;206:90-102doi: 10.1016/j.toxicon.2021.12.015.
Bermúdez-Guzmán, M. J., Jiménez-Vargas, J. M., Possani, L. D., Zamudio, F., Orozco-Gutiérrez, G., Oceguera-Contreras, E., Enríquez-Vara, J. N., Vazquez-Vuelvas, O. F., García-Villalvazo, P. E., & Valdez-Velázquez, L. L. (2022). Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon : official journal of the International Society on Toxinology, 20690-102. https://doi.org/10.1016/j.toxicon.2021.12.015
Bermúdez-Guzmán, M J, et al. "Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus." Toxicon : official journal of the International Society on Toxinology vol. 206 (2022): 90-102. doi: https://doi.org/10.1016/j.toxicon.2021.12.015
Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, Zamudio F, Orozco-Gutiérrez G, Oceguera-Contreras E, Enríquez-Vara JN, Vazquez-Vuelvas OF, García-Villalvazo PE, Valdez-Velázquez LL. Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon. 2022 Jan 30;206:90-102. doi: 10.1016/j.toxicon.2021.12.015. Epub 2021 Dec 31. PMID: 34973996.
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Correction to An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis.

Journal of natural products

Banerjee S, Gnanamani E, Lynch SR, Zuñiga FZ, Jiménez-Vargas JM, Possani LD, Zare RN.
PMID: 30203966
J Nat Prod. 2018 Sep 28;81(9):2161. doi: 10.1021/acs.jnatprod.8b00722. Epub 2018 Sep 11.

No abstract available.

Cite
Banerjee S, Gnanamani E, Lynch SR, et al. Correction to An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis. J Nat Prod. 2018;81(9):2161doi: 10.1021/acs.jnatprod.8b00722.
Banerjee, S., Gnanamani, E., Lynch, S. R., Zuñiga, F. Z., Jiménez-Vargas, J. M., Possani, L. D., & Zare, R. N. (2018). Correction to An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis. Journal of natural products, 81(9), 2161. https://doi.org/10.1021/acs.jnatprod.8b00722
Banerjee, Shibdas, et al. "Correction to An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis." Journal of natural products vol. 81,9 (2018): 2161. doi: https://doi.org/10.1021/acs.jnatprod.8b00722
Banerjee S, Gnanamani E, Lynch SR, Zuñiga FZ, Jiménez-Vargas JM, Possani LD, Zare RN. Correction to An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis. J Nat Prod. 2018 Sep 28;81(9):2161. doi: 10.1021/acs.jnatprod.8b00722. Epub 2018 Sep 11. PMID: 30203966.
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Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus.

Peptides

Jiménez-Vargas JM, Ramírez-Carreto S, Corzo G, Possani LD, Becerril B, Ortiz E.
PMID: 33862164
Peptides. 2021 Jul;141:170553. doi: 10.1016/j.peptides.2021.170553. Epub 2021 Apr 20.

Six peptides, belonging to the NDBP-4 family of scorpion antimicrobial peptides were structurally and functionally characterized. The sequence of the mature peptides VpCT1, VpCT2, VpCT3 and VpCT4 was inferred by transcriptomic analysis of the venom gland of the scorpion...

Cite
Jiménez-Vargas JM, Ramírez-Carreto S, Corzo G, et al. Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus. Peptides. 2021;141:170553doi: 10.1016/j.peptides.2021.170553.
Jiménez-Vargas, J. M., Ramírez-Carreto, S., Corzo, G., Possani, L. D., Becerril, B., & Ortiz, E. (2021). Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus. Peptides, 141170553. https://doi.org/10.1016/j.peptides.2021.170553
Jiménez-Vargas, Juana María, et al. "Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus." Peptides vol. 141 (2021): 170553. doi: https://doi.org/10.1016/j.peptides.2021.170553
Jiménez-Vargas JM, Ramírez-Carreto S, Corzo G, Possani LD, Becerril B, Ortiz E. Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus. Peptides. 2021 Jul;141:170553. doi: 10.1016/j.peptides.2021.170553. Epub 2021 Apr 20. PMID: 33862164.
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Beta-blocker therapy in elderly patients with renal dysfunction and heart failure.

Journal of geriatric cardiology : JGC

Martínez-Milla J, García MC, Palfy JA, Urquía MT, Castillo ML, Arbiol AD, Monteagudo ALR, Mariscal MLM, Jiménez-Varas I, Figuero SB, Franco-Pelaéz JA, Tuñón J.
PMID: 33613656
J Geriatr Cardiol. 2021 Jan 28;18(1):20-29. doi: 10.11909/j.issn.1671-5411.2021.01.005.

OBJECTIVE: To assess the role of beta-blockers (BB) in patients with chronic kidney disease (CKD) aged ≥ 75 years.METHODS AND RESULTS: From January 2008 to July 2014, we included 390 consecutive patients ≥ 75 years of age with ejection...

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Martínez-Milla J, García MC, Palfy JA, et al. Beta-blocker therapy in elderly patients with renal dysfunction and heart failure. J Geriatr Cardiol. 2021;18(1):20-29doi: 10.11909/j.issn.1671-5411.2021.01.005.
Martínez-Milla, J., García, M. C., Palfy, J. A., Urquía, M. T., Castillo, M. L., Arbiol, A. D., Monteagudo, A. L. R., Mariscal, M. L. M., Jiménez-Varas, I., Figuero, S. B., Franco-Pelaéz, J. A., & Tuñón, J. (2021). Beta-blocker therapy in elderly patients with renal dysfunction and heart failure. Journal of geriatric cardiology : JGC, 18(1), 20-29. https://doi.org/10.11909/j.issn.1671-5411.2021.01.005
Martínez-Milla, Juan, et al. "Beta-blocker therapy in elderly patients with renal dysfunction and heart failure." Journal of geriatric cardiology : JGC vol. 18,1 (2021): 20-29. doi: https://doi.org/10.11909/j.issn.1671-5411.2021.01.005
Martínez-Milla J, García MC, Palfy JA, Urquía MT, Castillo ML, Arbiol AD, Monteagudo ALR, Mariscal MLM, Jiménez-Varas I, Figuero SB, Franco-Pelaéz JA, Tuñón J. Beta-blocker therapy in elderly patients with renal dysfunction and heart failure. J Geriatr Cardiol. 2021 Jan 28;18(1):20-29. doi: 10.11909/j.issn.1671-5411.2021.01.005. PMID: 33613656; PMCID: PMC7868915.
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Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus.

Toxicon : official journal of the International Society on Toxinology

Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, Zamudio F, Orozco-Gutiérrez G, Oceguera-Contreras E, Enríquez-Vara JN, Vazquez-Vuelvas OF, García-Villalvazo PE, Valdez-Velázquez LL.
PMID: 34973996
Toxicon. 2021 Dec 31;206:90-102. doi: 10.1016/j.toxicon.2021.12.015. Epub 2021 Dec 31.

The venom of scorpions is a mixture of components that constitute a source of bioactive molecules. The venom of the scorpion Centruroides tecomanus contains peptides toxic to insects, however, to date no toxin responsible for this activity has yet...

Cite
Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, et al. Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon. 2021;206:90-102doi: 10.1016/j.toxicon.2021.12.015.
Bermúdez-Guzmán, M. J., Jiménez-Vargas, J. M., Possani, L. D., Zamudio, F., Orozco-Gutiérrez, G., Oceguera-Contreras, E., Enríquez-Vara, J. N., Vazquez-Vuelvas, O. F., García-Villalvazo, P. E., & Valdez-Velázquez, L. L. (2021). Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon : official journal of the International Society on Toxinology, 20690-102. https://doi.org/10.1016/j.toxicon.2021.12.015
Bermúdez-Guzmán, M J, et al. "Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus." Toxicon : official journal of the International Society on Toxinology vol. 206 (2021): 90-102. doi: https://doi.org/10.1016/j.toxicon.2021.12.015
Bermúdez-Guzmán MJ, Jiménez-Vargas JM, Possani LD, Zamudio F, Orozco-Gutiérrez G, Oceguera-Contreras E, Enríquez-Vara JN, Vazquez-Vuelvas OF, García-Villalvazo PE, Valdez-Velázquez LL. Biochemical characterization and insecticidal activity of isolated peptides from the venom of the scorpion Centruroides tecomanus. Toxicon. 2021 Dec 31;206:90-102. doi: 10.1016/j.toxicon.2021.12.015. Epub 2021 Dec 31. PMID: 34973996.
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Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects.

Gut

Jiménez-Vargas NN, Yu Y, Jensen DD, Bok DD, Wisdom M, Latorre R, Lopez C, Jaramillo-Polanco JO, Degro C, Guzman-Rodriguez M, Tsang Q, Snow Z, Schmidt BL, Reed DE, Lomax AE, Margolis KG, Stein C, Bunnett NW, Vanner SJ.
PMID: 33785555
Gut. 2021 Mar 30; doi: 10.1136/gutjnl-2021-324070. Epub 2021 Mar 30.

OBJECTIVE: The effectiveness of µ-opioid receptor (MOPr) agonists for treatment of visceral pain is compromised by constipation, respiratory depression, sedation and addiction. We investigated whether a fentanyl analogue, (±)-N-(3-fluoro-1-phenethylpiperidine-4-yl)-N-phenyl propionamide (NFEPP), which preferentially activates MOPr in acidified diseased tissues,...

Cite
Jiménez-Vargas NN, Yu Y, Jensen DD, et al. Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. Gut. 2021;doi: 10.1136/gutjnl-2021-324070.
Jiménez-Vargas, N. N., Yu, Y., Jensen, D. D., Bok, D. D., Wisdom, M., Latorre, R., Lopez, C., Jaramillo-Polanco, J. O., Degro, C., Guzman-Rodriguez, M., Tsang, Q., Snow, Z., Schmidt, B. L., Reed, D. E., Lomax, A. E., Margolis, K. G., Stein, C., Bunnett, N. W., & Vanner, S. J. (2021). Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. Gut, . https://doi.org/10.1136/gutjnl-2021-324070
Jiménez-Vargas, Nestor Nivardo, et al. "Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects." Gut vol. (2021). doi: https://doi.org/10.1136/gutjnl-2021-324070
Jiménez-Vargas NN, Yu Y, Jensen DD, Bok DD, Wisdom M, Latorre R, Lopez C, Jaramillo-Polanco JO, Degro C, Guzman-Rodriguez M, Tsang Q, Snow Z, Schmidt BL, Reed DE, Lomax AE, Margolis KG, Stein C, Bunnett NW, Vanner SJ. Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. Gut. 2021 Mar 30; doi: 10.1136/gutjnl-2021-324070. Epub 2021 Mar 30. PMID: 33785555; PMCID: PMC8608554.
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Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects.

Gut

Jiménez-Vargas NN, Yu Y, Jensen DD, Bok DD, Wisdom M, Latorre R, Lopez C, Jaramillo-Polanco JO, Degro C, Guzman-Rodriguez M, Tsang Q, Snow Z, Schmidt BL, Reed DE, Lomax AE, Margolis KG, Stein C, Bunnett NW, Vanner SJ.
PMID: 33785555
Gut. 2021 Mar 30; doi: 10.1136/gutjnl-2021-324070. Epub 2021 Mar 30.

OBJECTIVE: The effectiveness of µ-opioid receptor (MOPr) agonists for treatment of visceral pain is compromised by constipation, respiratory depression, sedation and addiction. We investigated whether a fentanyl analogue, (±)-N-(3-fluoro-1-phenethylpiperidine-4-yl)-N-phenyl propionamide (NFEPP), which preferentially activates MOPr in acidified diseased tissues,...

Cite
Jiménez-Vargas NN, Yu Y, Jensen DD, et al. Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. Gut. 2021;doi: 10.1136/gutjnl-2021-324070.
Jiménez-Vargas, N. N., Yu, Y., Jensen, D. D., Bok, D. D., Wisdom, M., Latorre, R., Lopez, C., Jaramillo-Polanco, J. O., Degro, C., Guzman-Rodriguez, M., Tsang, Q., Snow, Z., Schmidt, B. L., Reed, D. E., Lomax, A. E., Margolis, K. G., Stein, C., Bunnett, N. W., & Vanner, S. J. (2021). Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. Gut, . https://doi.org/10.1136/gutjnl-2021-324070
Jiménez-Vargas, Nestor Nivardo, et al. "Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects." Gut vol. (2021). doi: https://doi.org/10.1136/gutjnl-2021-324070
Jiménez-Vargas NN, Yu Y, Jensen DD, Bok DD, Wisdom M, Latorre R, Lopez C, Jaramillo-Polanco JO, Degro C, Guzman-Rodriguez M, Tsang Q, Snow Z, Schmidt BL, Reed DE, Lomax AE, Margolis KG, Stein C, Bunnett NW, Vanner SJ. Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects. Gut. 2021 Mar 30; doi: 10.1136/gutjnl-2021-324070. Epub 2021 Mar 30. PMID: 33785555; PMCID: PMC8608554.
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