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Showing 1 to 12 of 469 entries
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Reaching out to students from Title I schools

Non-school settings

Johnston V.
GSID: iS0J2ehtw-sJ
V Johnston, CD Martelli - The Reading Teacher, 2019 - Wiley Online Library

A university's literacy festival can promote reading and foster the idea that books make a difference, especially to undersupported students from Title I schools. A literacy festival …

A perspective on Wright and Linacre.

Archives of physical medicine and rehabilitation

Johnston MV, Findley TW.
PMID: 2334293
Arch Phys Med Rehabil. 1990 May;71(6):439-40.

No abstract available.

Modeling nanoscale inhomogeneities for quantitative HAADF STEM imaging.

Physical review letters

Aveyard R, Ferrando R, Johnston RL, Yuan J.
PMID: 25170712
Phys Rev Lett. 2014 Aug 15;113(7):075501. doi: 10.1103/PhysRevLett.113.075501. Epub 2014 Aug 13.

High-angle annular dark-field scanning transmission electron microscopy in conjunction with image simulation is an important tool to determine the structure of nanomaterials. We show that molecular dynamics calculations can be combined with multislice image simulations to account for the...

Targeting dendritic cells: a promising strategy to improve vaccine effectiveness.

Clinical & translational immunology

Macri C, Dumont C, Johnston AP, Mintern JD.
PMID: 27217957
Clin Transl Immunology. 2016 Mar 18;5(3):e66. doi: 10.1038/cti.2016.6. eCollection 2016 Mar.

Dendritic cell (DC) targeting is a novel strategy to enhance vaccination efficacy. This approach is based on the in situ delivery of antigen via antibodies that are specific for endocytic receptors expressed at the surface of DCs. Here we...

Everolimus and intensive behavioral therapy in an adolescent with tuberous sclerosis complex and severe behavior.

Epilepsy & behavior case reports

Gipson TT, Jennett H, Wachtel L, Gregory M, Poretti A, Johnston MV.
PMID: 25667844
Epilepsy Behav Case Rep. 2013 Aug 24;1:122-5. doi: 10.1016/j.ebcr.2013.06.004. eCollection 2013.

BACKGROUND: Self-injury and aggression have been reported in individuals with TSC (tuberous sclerosis complex), yet few data exist about treatment. Everolimus, an mTOR inhibitor, has been FDA-approved for subependymal giant cell astrocytomas (SEGAs) and renal angiomyolipomas in TSC. However,...

Development of an Ad5H3 Chimera Using the "Antigen Capsid-Incorporation" Strategy for an Alternative Vaccination Approach.

The open virology journal

Gu L, Icyuz M, Krendelchtchikova V, Krendelchtchikov A, Johnston AE, Matthews QL.
PMID: 27335626
Open Virol J. 2016 Apr 26;10:10-20. doi: 10.2174/1874357901610010010. eCollection 2016.

BACKGROUND: Adenovirus type 5 (Ad5) achieved success as a conventional transgene vaccine vector in preclinical trials, however; achieved poor efficiency in some of the clinical trials, due to the major hurdle associated with Ad5 pre-existing immunity (PEI) in the...

Quantification of intracellular payload release from polymersome nanoparticles.

Scientific reports

Scarpa E, Bailey JL, Janeczek AA, Stumpf PS, Johnston AH, Oreffo RO, Woo YL, Cheong YC, Evans ND, Newman TA.
PMID: 27404770
Sci Rep. 2016 Jul 11;6:29460. doi: 10.1038/srep29460.

Polymersome nanoparticles (PMs) are attractive candidates for spatio-temporal controlled delivery of therapeutic agents. Although many studies have addressed cellular uptake of solid nanoparticles, there is very little data available on intracellular release of molecules encapsulated in membranous carriers, such...

Structures and Energy Landscapes of Hydrated Sulfate Clusters.

Journal of chemical theory and computation

Smeeton LC, Farrell JD, Oakley MT, Wales DJ, Johnston RL.
PMID: 26574432
J Chem Theory Comput. 2015 May 12;11(5):2377-84. doi: 10.1021/acs.jctc.5b00151. Epub 2015 Apr 10.

The sulfate ion is the most kosmotropic member of the Hofmeister series, but the chemical origins of this effect are unclear. We present a global optimization and energy landscape mapping study of microhydrated sulfate ions, SO4(2-)(H2O)n, in the size...

Visualizing energy landscapes with metric disconnectivity graphs.

Journal of computational chemistry

Smeeton LC, Oakley MT, Johnston RL.
PMID: 24866379
J Comput Chem. 2014 Jul 30;35(20):1481-90. doi: 10.1002/jcc.23643. Epub 2014 May 28.

The visualization of multidimensional energy landscapes is important, providing insight into the kinetics and thermodynamics of a system, as well the range of structures a system can adopt. It is, however, highly nontrivial, with the number of dimensions required...

A DFT study of oxygen dissociation on platinum based nanoparticles.

Nanoscale

Jennings PC, Aleksandrov HA, Neyman KM, Johnston RL.
PMID: 24296728
Nanoscale. 2014 Jan 21;6(2):1153-1165. doi: 10.1039/c3nr04750d.

Density functional theory calculations are performed on 38 and 79 metal atom truncated octahedron clusters to study oxygen dissociation as a model for the initial stage of the oxygen reduction reaction. Pure platinum and alloyed platinum-titanium core-shell systems are...

Click-engineered, bioresponsive, drug-loaded PEG spheres.

Advanced materials (Deerfield Beach, Fla.)

Yap HP, Johnston AP, Such GK, Yan Y, Caruso F.
PMID: 26042942
Adv Mater. 2009 Nov 20;21(43):4348-52. doi: 10.1002/adma.200900421. Epub 2009 Jun 24.

A click-chemistry approach to synthesize bioresponsive poly(ethylene glycol acrylate) particles is described. The particles are loaded with a model anticancer drug (doxorubicin, DOX), and undergo simultaneous particle deconstruction and DOX release upon specific activation by the simulated environment of...

Twenty-four hour quantitative-EEG and in-vivo glutamate biosensor detects activity and circadian rhythm dependent biomarkers of pathogenesis in Mecp2 null mice.

Frontiers in systems neuroscience

Johnston MV, Ammanuel S, O'Driscoll C, Wozniak A, Naidu S, Kadam SD.
PMID: 25018705
Front Syst Neurosci. 2014 Jun 27;8:118. doi: 10.3389/fnsys.2014.00118. eCollection 2014.

Mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (Mecp2) cause most cases of Rett syndrome (RTT). Currently there is no cure for RTT. Abnormal EEGs are found in 100% of RTT cases and are associated with severe sleep...

Showing 1 to 12 of 469 entries