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Showing 1 to 12 of 117 entries
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Biosimilars and the extrapolation of indications for inflammatory conditions.

Biologics : targets & therapy

Tesser JR, Furst DE, Jacobs I.
PMID: 28255229
Biologics. 2017 Feb 17;11:5-11. doi: 10.2147/BTT.S124476. eCollection 2017.

Extrapolation is the approval of a biosimilar for use in an indication held by the originator biologic not directly studied in a comparative clinical trial with the biosimilar. Extrapolation is a scientific rationale that bridges all the data collected...

On the modeling of narrow gaps using the standard boundary element method.

The Journal of the Acoustical Society of America

Cutanda V, Juhl PM, Jacobsen F.
PMID: 11325100
J Acoust Soc Am. 2001 Apr;109(4):1296-303. doi: 10.1121/1.1350399.

Numerical methods based on the Helmholtz integral equation are well suited for solving acoustic scattering and diffraction problems at relatively low frequencies. However, it is well known that the standard method becomes degenerate if the objects that disturb the...

A crystalline form of benzylpenicillinic acid.

Journal of the American Chemical Society

TRENNER NR, BUHS RP.
PMID: 18882518
J Am Chem Soc. 1948 Sep;70(9):2897-2900. doi: 10.1021/ja01189a019.

No abstract available.

Steric control of a bridging ligand for high-nuclearity metallamacrocycle formation: a highly puckered 60-membered icosanuclear metalladiazamacrocycle.

Inorganic chemistry

Moon D, Lee K, John RP, Kim GH, Suh BJ, Lah MS.
PMID: 16999391
Inorg Chem. 2006 Oct 02;45(20):7991-3. doi: 10.1021/ic060646d.

A novel S4-symmetric icosanuclear manganese metalladiazamacrocycle was synthesized using a pentadentate ligand, N-3-phenyl-trans-2-propenoylsalicylhydrazide (H3L), that has a rigid and bulky terminal N-acyl group. A 20 cyclic repeat of an--(Mn-N-N)--linkage resulted in a highly puckered diaza-bridged 60-membered icosanuclear metallamacrocycle. The...

Modulation of the ring size and nuclearity of metallamacrocycles via the steric effect of ligands: preparation and characterization of 18-membered hexanuclear, 24-membered octanuclear, and 30-membered decanuclear manganese metalladiazamacrocycles with alpha- and beta-branched N-acylsalicylhydrazides.

Inorganic chemistry

John RP, Lee K, Kim BJ, Suh BJ, Rhee H, Lah MS.
PMID: 16180873
Inorg Chem. 2005 Oct 03;44(20):7109-21. doi: 10.1021/ic050891h.

Hexanuclear, octanuclear, and decanuclear manganese metalladiazamacrocycles have been prepared by reacting a series of pentadentate ligands, N-acylsalicylhydrazides (N-(3-methylbutanoyl)salicylhydrazide (H(3)3-mbshz), N-(phenylacetyl)salicylhydrazide (H(3)pashz), N-(3,3-dimethylbutanoyl)salicylhydrazide (H(3)3-dmbshz), N-(2-methylpropanoyl)salicylhydrazide (H(3)2-mpshz), N-((R,S)-2-methylbutanoyl)salicylhydrazide (H(3)RS-2-mbshz), N-((S)-2-methylbutanoyl)salicylhydrazide (H(3)S-2-mbshz), and N-(2,2-dimethylpropanoyl)salicylhydrazide (H(3)2-dmpshz)), with manganese(II) acetate tetrahydrate. The self-assembled, supramolecular...

On the applicability of the spherical wave expansion with a single origin for near-field acoustical holography.

The Journal of the Acoustical Society of America

Gomes J, Hald J, Juhl P, Jacobsen F.
PMID: 19275311
J Acoust Soc Am. 2009 Mar;125(3):1529-37. doi: 10.1121/1.3068451.

The spherical wave expansion with a single origin is sometimes used in connection with near-field acoustical holography to determine the sound field on the surface of a source. The radiated field is approximated by a truncated expansion, and the...

Efficient Water Reduction with sp.

Angewandte Chemie (International ed. in English)

Flinker M, Yin H, Juhl RW, Eikeland EZ, Overgaard J, Nielsen DU, Skrydstrup T.
PMID: 29076608
Angew Chem Int Ed Engl. 2017 Dec 11;56(50):15910-15915. doi: 10.1002/anie.201709685. Epub 2017 Nov 17.

A series of crystalline sp

Psychometric Validation of the BODY-Q in Danish Patients Undergoing Weight Loss and Body Contouring Surgery.

Plastic and reconstructive surgery. Global open

Poulsen L, Klassen A, Rose M, Roessler KK, Juhl CB, Støving RK, Cano S, Sørensen JA.
PMID: 29184741
Plast Reconstr Surg Glob Open. 2017 Oct 20;5(10):e1529. doi: 10.1097/GOX.0000000000001529. eCollection 2017 Oct.

BACKGROUND: A well-developed patient-reported outcome instrument is needed for use in Danish bariatric and body contouring patients. The BODY-Q is designed to measure changes in important patient outcomes over the entire patient journey, from obesity to post-body contouring surgery....

eLife

Knight JR, Vlahov N, Gay DM, Ridgway RA, Faller WJ, Proud C, Mallucci GR, von der Haar T, Smales CM, Willis AE, Sansom OJ.
PMID: 34895463
Elife. 2021 Dec 13;10. doi: 10.7554/eLife.69729.

Increased protein synthesis supports the rapid cell proliferation associated with cancer. The

Effects of Patient-Initiated Visits on Patient Satisfaction and Clinical Outcomes in a Type 1 Diabetes Outpatient Clinic: A 2-Year Randomized Controlled Study.

Diabetes care

Drøjdahl Ryg N, Gram J, Haghighi M, Juhl CB.
PMID: 34301734
Diabetes Care. 2021 Jul 22; doi: 10.2337/dc20-3083. Epub 2021 Jul 22.

OBJECTIVE: We investigated the effects of replacing regular outpatient follow-up through prescheduled visits with patient-initiated visits on patient satisfaction and clinical variables of type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: A 24-month randomized controlled trial in which adults with...

In memoriam Arthur Chandler Jr., M.D. Dec. 23, 1928--Dec. 4, 1969.

Radiology

Juhl JH, Swingle JD.
PMID: 4914470
Radiology. 1970 Aug;96(2):459. doi: 10.1148/96.2.459.

No abstract available.

Antimicrobial peptides: mechanism of action and lipid-mediated synergistic interactions within membranes.

Faraday discussions

Juhl DW, Glattard E, Aisenbrey C, Bechinger B.
PMID: 34533138
Faraday Discuss. 2021 Sep 17; doi: 10.1039/d0fd00041h. Epub 2021 Sep 17.

Biophysical and structural studies of peptide-lipid interactions, peptide topology and dynamics have changed our view of how antimicrobial peptides insert and interact with membranes. Clearly, both peptides and lipids are highly dynamic, and change and mutually adapt their conformation,...

Showing 1 to 12 of 117 entries