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Showing 1 to 12 of 497 entries
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Stereoselective synthesis of aryl cyclopentene scaffolds by Heck-Matsuda desymmetrization of 3-cyclopentenol.

Chemistry (Weinheim an der Bergstrasse, Germany)

Angnes RA, Oliveira JM, Oliveira CC, Martins NC, Correia CR.
PMID: 25155478
Chemistry. 2014 Oct 06;20(41):13117-21. doi: 10.1002/chem.201404159. Epub 2014 Aug 26.

A new enantioselective Heck-Matsuda desymmetrization reaction was accomplished by using 3-cyclopentenol to produce chiral five-membered 4-aryl cyclopentenol scaffolds in good yields and high ee's, together with some 3-aryl-cyclopentanones as minor products. Mechanistically, the hydroxyl group of 3-cyclopentenol acts as...

Ebola.

Journal of the Intensive Care Society

Brown JM, Smith RN.
PMID: 28979386
J Intensive Care Soc. 2015 Feb;16(1):88. doi: 10.1177/1751143714564510. Epub 2015 Feb 17.

No abstract available.

Frontiers in microbiology

Santos DKF, Resende AHM, de Almeida DG, Soares da Silva RCF, Rufino RD, Luna JM, Banat IM, Sarubbo LA.
PMID: 28507538
Front Microbiol. 2017 May 01;8:767. doi: 10.3389/fmicb.2017.00767. eCollection 2017.

The aim of the present study was to investigate the potential application of the biosurfactant from

Response Surface Methodology for Optimizing the Production of Biosurfactant by .

Frontiers in microbiology

Almeida DG, Soares da Silva RC, Luna JM, Rufino RD, Santos VA, Sarubbo LA.
PMID: 28223971
Front Microbiol. 2017 Feb 07;8:157. doi: 10.3389/fmicb.2017.00157. eCollection 2017.

Biosurfactant production optimization by

Medication regimen complexity in adults and the elderly in a primary healthcare setting: determination of high and low complexities.

Pharmacy practice

Ferreira JM, Galato D, Melo AC.
PMID: 26759621
Pharm Pract (Granada). 2015 Oct-Dec;13(4):659. doi: 10.18549/PharmPract.2015.04.659. Epub 2015 Dec 15.

BACKGROUND: The complexity of a medication regimen is related to the multiple characteristics of the prescribed regimen and can negatively influence the health outcomes of patients.OBJECTIVE: To propose cut-off points in the complexity of pharmacotherapy to distinguish between patients...

Characteristics of adherence to methadone maintenance treatment over a 15-year period among homeless adults experiencing mental illness.

Addictive behaviors reports

Parpouchi M, Moniruzzaman A, Rezansoff SN, Russolillo A, Somers JM.
PMID: 29450244
Addict Behav Rep. 2017 Sep 23;6:106-111. doi: 10.1016/j.abrep.2017.09.001. eCollection 2017 Dec.

BACKGROUND: Methadone maintenance treatment (MMT) has important protective effects related to reduced illicit opioid use, infectious disease transmission, and overdose mortality. Adherence to MMT has not been examined among homeless people. We measured MMT adherence and reported relevant characteristics...

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.

Cell reports

Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, Yang JD, Reznik E, Sadeghi S, Pedamallu CS, Ojesina AI, Hess JM, Auman JT, Rhie SK, Bowlby R, Borad MJ, Zhu AX, Stuart JM, Sander C, Akbani R, Cherniack AD, Deshpande V, Mounajjed T, Foo WC, Torbenson MS, Kleiner DE, Laird PW, Wheeler DA, McRee AJ, Bathe OF, Andersen JB, Bardeesy N, Roberts LR, Kwong LN.
PMID: 28658632
Cell Rep. 2017 Jun 27;19(13):2878-2880. doi: 10.1016/j.celrep.2017.06.008.

No abstract available.

Metabolic parameters and responsiveness of isolated iliac artery in LDLr.

American journal of cardiovascular disease

Garcia NF, Sponton AC, Delbin MA, Parente JM, Castro MM, Zanesco A, de Moraes C.
PMID: 28533932
Am J Cardiovasc Dis. 2017 Apr 15;7(2):64-71. eCollection 2017.

Physical inactivity and dyslipidemia are considered risk factors for cardiovascular diseases. There are few studies evaluating the effects of physical exercise in small-caliber artery in a model that mimics familial hypercholesterolemia. The aim of this study was to examine...

Isolation and biochemical characterization of bradykinin-potentiating peptides from .

The journal of venomous animals and toxins including tropical diseases

Fucase TM, Sciani JM, Cavalcante I, Viala VL, Chagas BB, Pimenta DC, Spencer PJ.
PMID: 28670326
J Venom Anim Toxins Incl Trop Dis. 2017 Jun 26;23:33. doi: 10.1186/s40409-017-0124-9. eCollection 2017.

BACKGROUND: Venoms represent a still underexplored reservoir of bioactive components that might mitigate or cure diseases in conditions in which conventional therapy is ineffective. The bradykinin-potentiating peptides (BPPs) comprise a class of angiotensin-I converting enzyme (ACE) inhibitors. The BPPs...

Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells.

PeerJ

Lages YM, Nascimento JM, Lemos GA, Galina A, Castilho LR, Rehen SK.
PMID: 26713239
PeerJ. 2015 Dec 10;3:e1486. doi: 10.7717/peerj.1486. eCollection 2015.

Oxygen concentration should be carefully regulated in all living tissues, beginning at the early embryonic stages. Unbalances in oxygen regulation can lead to cell death and disease. However, to date, few studies have investigated the consequences of variations in...

The carbon price: a toothless tool for material efficiency?.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Skelton ACH, Allwood JM.
PMID: 28461438
Philos Trans A Math Phys Eng Sci. 2017 Jun 13;375(2095). doi: 10.1098/rsta.2016.0374.

This article explores whether a carbon price will effectively encourage the more efficient use of greenhouse gas intensive materials such as steel. The article identifies a range of distortions that arise when some of the restrictive assumptions of neoclassical...

Industry 1.61803: the transition to an industry with reduced material demand fit for a low carbon future.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Allwood JM, Gutowski TG, Serrenho AC, Skelton ACH, Worrell E.
PMID: 28461426
Philos Trans A Math Phys Eng Sci. 2017 Jun 13;375(2095). doi: 10.1098/rsta.2016.0361.

Arising from a discussion meeting in September 2016, this editorial introduces a special issue on the transition to a future industrial system with greatly reduced demand for material production and attempts to synthesize the main findings. The motivation for...

Showing 1 to 12 of 497 entries