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A simple and convenient one-pot synthesis of substituted isoindolin-1-ones via lithiation, substitution and cyclization of N'-benzyl-N,N-dimethylureas.

Beilstein journal of organic chemistry

Smith K, El-Hiti GA, Hegazy AS, Kariuki B.
PMID: 21977206
Beilstein J Org Chem. 2011;7:1219-27. doi: 10.3762/bjoc.7.142. Epub 2011 Sep 06.

Lithiation of N'-benzyl-N,N-dimethylurea and its substituted derivatives with t-BuLi (3.3 equiv) in anhydrous THF at 0 °C followed by reaction with various electrophiles afforded a range of 3-substituted isoindolin-1-ones in high yields.

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Smith K, El-Hiti GA, Hegazy AS, et al. A simple and convenient one-pot synthesis of substituted isoindolin-1-ones via lithiation, substitution and cyclization of N'-benzyl-N,N-dimethylureas. Beilstein J Org Chem. 2011;7:1219-27doi: 10.3762/bjoc.7.142.
Smith, K., El-Hiti, G. A., Hegazy, A. S., & Kariuki, B. (2011). A simple and convenient one-pot synthesis of substituted isoindolin-1-ones via lithiation, substitution and cyclization of N'-benzyl-N,N-dimethylureas. Beilstein journal of organic chemistry, 71219-27. https://doi.org/10.3762/bjoc.7.142
Smith, Keith, et al. "A simple and convenient one-pot synthesis of substituted isoindolin-1-ones via lithiation, substitution and cyclization of N'-benzyl-N,N-dimethylureas." Beilstein journal of organic chemistry vol. 7 (2011): 1219-27. doi: https://doi.org/10.3762/bjoc.7.142
Smith K, El-Hiti GA, Hegazy AS, Kariuki B. A simple and convenient one-pot synthesis of substituted isoindolin-1-ones via lithiation, substitution and cyclization of N'-benzyl-N,N-dimethylureas. Beilstein J Org Chem. 2011;7:1219-27. doi: 10.3762/bjoc.7.142. Epub 2011 Sep 06. PMID: 21977206; PMCID: PMC3182431.
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Carriage rate and serotypes of .

African journal of laboratory medicine

Githii S, Revathi G, Muigai A, Kariuki S.
PMID: 29043160
Afr J Lab Med. 2013 May 20;2(1):45. doi: 10.4102/ajlm.v2i1.45. eCollection 2013.

No abstract available.

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Githii S, Revathi G, Muigai A, et al. Carriage rate and serotypes of . Afr J Lab Med. 2013;2(1):45doi: 10.4102/ajlm.v2i1.45.
Githii, S., Revathi, G., Muigai, A., & Kariuki, S. (2013). Carriage rate and serotypes of . African journal of laboratory medicine, 2(1), 45. https://doi.org/10.4102/ajlm.v2i1.45
Githii, Susan, et al. "Carriage rate and serotypes of ." African journal of laboratory medicine vol. 2,1 (2013): 45. doi: https://doi.org/10.4102/ajlm.v2i1.45
Githii S, Revathi G, Muigai A, Kariuki S. Carriage rate and serotypes of . Afr J Lab Med. 2013 May 20;2(1):45. doi: 10.4102/ajlm.v2i1.45. eCollection 2013. PMID: 29043160; PMCID: PMC5637771.
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Community case management of childhood illness in sub-Saharan Africa - findings from a cross-sectional survey on policy and implementation.

Journal of global health

Rasanathan K, Muñiz M, Bakshi S, Kumar M, Solano A, Kariuki W, George A, Sylla M, Nefdt R, Young M, Diaz T.
PMID: 25520791
J Glob Health. 2014 Dec;4(2):020401. doi: 10.7189/jogh.04.020401.

BACKGROUND: Community case management (CCM) involves training, supporting, and supplying community health workers (CHWs) to assess, classify and manage sick children with limited access to care at health facilities, in their communities. This paper aims to provide an overview...

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Rasanathan K, Muñiz M, Bakshi S, et al. Community case management of childhood illness in sub-Saharan Africa - findings from a cross-sectional survey on policy and implementation. J Glob Health. 2014;4(2):020401doi: 10.7189/jogh.04.020401.
Rasanathan, K., Muñiz, M., Bakshi, S., Kumar, M., Solano, A., Kariuki, W., George, A., Sylla, M., Nefdt, R., Young, M., & Diaz, T. (2014). Community case management of childhood illness in sub-Saharan Africa - findings from a cross-sectional survey on policy and implementation. Journal of global health, 4(2), 020401. https://doi.org/10.7189/jogh.04.020401
Rasanathan, Kumanan, et al. "Community case management of childhood illness in sub-Saharan Africa - findings from a cross-sectional survey on policy and implementation." Journal of global health vol. 4,2 (2014): 020401. doi: https://doi.org/10.7189/jogh.04.020401
Rasanathan K, Muñiz M, Bakshi S, Kumar M, Solano A, Kariuki W, George A, Sylla M, Nefdt R, Young M, Diaz T. Community case management of childhood illness in sub-Saharan Africa - findings from a cross-sectional survey on policy and implementation. J Glob Health. 2014 Dec;4(2):020401. doi: 10.7189/jogh.04.020401. PMID: 25520791; PMCID: PMC4267096.
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Validation of the St. George's Respiratory Questionnaire in Nepal.

Chronic obstructive pulmonary diseases (Miami, Fla.)

Sherpa CT, LeClerq SL, Singh S, Naithani N, Pangeni R, Karki A, Chokhani RK, Han M, Gyetko M, Tielsch JM, Checkley W.
PMID: 28848850
Chronic Obstr Pulm Dis. 2015 Sep 02;2(4):281-289. doi: 10.15326/jcopdf.2.4.2014.0156.

The St. George's Respiratory Questionnaire (SGRQ) is a standardized questionnaire for measuring impaired health and perceived well-being in chronic airway disease, but it is not available in the Nepali language. We translated the original SGRQ into Nepali and validated...

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Sherpa CT, LeClerq SL, Singh S, et al. Validation of the St. George's Respiratory Questionnaire in Nepal. Chronic Obstr Pulm Dis. 2015;2(4):281-289doi: 10.15326/jcopdf.2.4.2014.0156.
Sherpa, C. T., LeClerq, S. L., Singh, S., Naithani, N., Pangeni, R., Karki, A., Chokhani, R. K., Han, M., Gyetko, M., Tielsch, J. M., & Checkley, W. (2015). Validation of the St. George's Respiratory Questionnaire in Nepal. Chronic obstructive pulmonary diseases (Miami, Fla.), 2(4), 281-289. https://doi.org/10.15326/jcopdf.2.4.2014.0156
Sherpa, Chundak T, et al. "Validation of the St. George's Respiratory Questionnaire in Nepal." Chronic obstructive pulmonary diseases (Miami, Fla.) vol. 2,4 (2015): 281-289. doi: https://doi.org/10.15326/jcopdf.2.4.2014.0156
Sherpa CT, LeClerq SL, Singh S, Naithani N, Pangeni R, Karki A, Chokhani RK, Han M, Gyetko M, Tielsch JM, Checkley W. Validation of the St. George's Respiratory Questionnaire in Nepal. Chronic Obstr Pulm Dis. 2015 Sep 02;2(4):281-289. doi: 10.15326/jcopdf.2.4.2014.0156. PMID: 28848850; PMCID: PMC5556824.
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Follow-up Study on Electroconvulsive Therapy in Treatment-resistant Depressed Patients after Remission: A Chart Review.

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Tokutsu Y, Umene-Nakano W, Shinkai T, Yoshimura R, Okamoto T, Katsuki A, Hori H, Ikenouchi-Sugita A, Hayashi K, Atake K, Nakamura J.
PMID: 23678353
Clin Psychopharmacol Neurosci. 2013 Apr;11(1):34-8. doi: 10.9758/cpn.2013.11.1.34. Epub 2013 Apr 24.

OBJECTIVE: Electroconvulsive therapy (ECT) has proven to be effective in treatment-resistant depression (TRD). In recent reports, 70% to 90% of patients with TRD responded to ECT. However, post-ECT relapse is a significant problem. There are no studies investigating risk...

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Tokutsu Y, Umene-Nakano W, Shinkai T, et al. Follow-up Study on Electroconvulsive Therapy in Treatment-resistant Depressed Patients after Remission: A Chart Review. Clin Psychopharmacol Neurosci. 2013;11(1):34-8doi: 10.9758/cpn.2013.11.1.34.
Tokutsu, Y., Umene-Nakano, W., Shinkai, T., Yoshimura, R., Okamoto, T., Katsuki, A., Hori, H., Ikenouchi-Sugita, A., Hayashi, K., Atake, K., & Nakamura, J. (2013). Follow-up Study on Electroconvulsive Therapy in Treatment-resistant Depressed Patients after Remission: A Chart Review. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 11(1), 34-8. https://doi.org/10.9758/cpn.2013.11.1.34
Tokutsu, Yuki, et al. "Follow-up Study on Electroconvulsive Therapy in Treatment-resistant Depressed Patients after Remission: A Chart Review." Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology vol. 11,1 (2013): 34-8. doi: https://doi.org/10.9758/cpn.2013.11.1.34
Tokutsu Y, Umene-Nakano W, Shinkai T, Yoshimura R, Okamoto T, Katsuki A, Hori H, Ikenouchi-Sugita A, Hayashi K, Atake K, Nakamura J. Follow-up Study on Electroconvulsive Therapy in Treatment-resistant Depressed Patients after Remission: A Chart Review. Clin Psychopharmacol Neurosci. 2013 Apr;11(1):34-8. doi: 10.9758/cpn.2013.11.1.34. Epub 2013 Apr 24. PMID: 23678353; PMCID: PMC3650296.
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Serum proBDNF/BDNF and response to fluvoxamine in drug-naïve first-episode major depressive disorder patients.

Annals of general psychiatry

Yoshimura R, Kishi T, Hori H, Atake K, Katsuki A, Nakano-Umene W, Ikenouchi-Sugita A, Iwata N, Nakamura J.
PMID: 25089150
Ann Gen Psychiatry. 2014 Jul 09;13:19. doi: 10.1186/1744-859X-13-19. eCollection 2014.

BACKGROUND: We investigated the association between serum proBDNF, a precursor of brain-derived neurotrophic factor (BDNF), and response to fluvoxamine in patients with major depressive disorder (MDD) using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision...

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Yoshimura R, Kishi T, Hori H, et al. Serum proBDNF/BDNF and response to fluvoxamine in drug-naïve first-episode major depressive disorder patients. Ann Gen Psychiatry. 2014;13:19doi: 10.1186/1744-859X-13-19.
Yoshimura, R., Kishi, T., Hori, H., Atake, K., Katsuki, A., Nakano-Umene, W., Ikenouchi-Sugita, A., Iwata, N., & Nakamura, J. (2014). Serum proBDNF/BDNF and response to fluvoxamine in drug-naïve first-episode major depressive disorder patients. Annals of general psychiatry, 1319. https://doi.org/10.1186/1744-859X-13-19
Yoshimura, Reiji, et al. "Serum proBDNF/BDNF and response to fluvoxamine in drug-naïve first-episode major depressive disorder patients." Annals of general psychiatry vol. 13 (2014): 19. doi: https://doi.org/10.1186/1744-859X-13-19
Yoshimura R, Kishi T, Hori H, Atake K, Katsuki A, Nakano-Umene W, Ikenouchi-Sugita A, Iwata N, Nakamura J. Serum proBDNF/BDNF and response to fluvoxamine in drug-naïve first-episode major depressive disorder patients. Ann Gen Psychiatry. 2014 Jul 09;13:19. doi: 10.1186/1744-859X-13-19. eCollection 2014. PMID: 25089150; PMCID: PMC4118273.
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Comparison of lithium, aripiprazole and olanzapine as augmentation to paroxetine for inpatients with major depressive disorder.

Therapeutic advances in psychopharmacology

Yoshimura R, Hori H, Umene-Nakano W, Ikenouchi-Sugita A, Katsuki A, Atake K, Nakamura J.
PMID: 25057345
Ther Adv Psychopharmacol. 2014 Jun;4(3):123-9. doi: 10.1177/2045125313514767.

BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are considered first-line treatments for major depressive disorders (MDD). It has been reported, however, that 30-40% of patients with MDD who received SSRIs failed to respond to treatment. Use of lithium (Li) to...

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Yoshimura R, Hori H, Umene-Nakano W, et al. Comparison of lithium, aripiprazole and olanzapine as augmentation to paroxetine for inpatients with major depressive disorder. Ther Adv Psychopharmacol. 2014;4(3):123-9doi: 10.1177/2045125313514767.
Yoshimura, R., Hori, H., Umene-Nakano, W., Ikenouchi-Sugita, A., Katsuki, A., Atake, K., & Nakamura, J. (2014). Comparison of lithium, aripiprazole and olanzapine as augmentation to paroxetine for inpatients with major depressive disorder. Therapeutic advances in psychopharmacology, 4(3), 123-9. https://doi.org/10.1177/2045125313514767
Yoshimura, Reiji, et al. "Comparison of lithium, aripiprazole and olanzapine as augmentation to paroxetine for inpatients with major depressive disorder." Therapeutic advances in psychopharmacology vol. 4,3 (2014): 123-9. doi: https://doi.org/10.1177/2045125313514767
Yoshimura R, Hori H, Umene-Nakano W, Ikenouchi-Sugita A, Katsuki A, Atake K, Nakamura J. Comparison of lithium, aripiprazole and olanzapine as augmentation to paroxetine for inpatients with major depressive disorder. Ther Adv Psychopharmacol. 2014 Jun;4(3):123-9. doi: 10.1177/2045125313514767. PMID: 25057345; PMCID: PMC4107705.
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Three-dimensional morphological chirality induction using high magnetic fields in membrane tubes prepared by a silicate garden reaction.

The journal of physical chemistry. B

Duan W, Kitamura S, Uechi I, Katsuki A, Tanimoto Y.
PMID: 16852682
J Phys Chem B. 2005 Jul 21;109(28):13445-50. doi: 10.1021/jp050469m.

Using a vertical superconducting magnet (max. 15 T), we studied magnetic field effects on membrane tube morphology prepared by a silicate garden reaction. At zero field, semipermeable membrane tubes grew upward when metal salts were added to a sodium...

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Duan W, Kitamura S, Uechi I, et al. Three-dimensional morphological chirality induction using high magnetic fields in membrane tubes prepared by a silicate garden reaction. J Phys Chem B. 2005;109(28):13445-50doi: 10.1021/jp050469m.
Duan, W., Kitamura, S., Uechi, I., Katsuki, A., & Tanimoto, Y. (2005). Three-dimensional morphological chirality induction using high magnetic fields in membrane tubes prepared by a silicate garden reaction. The journal of physical chemistry. B, 109(28), 13445-50. https://doi.org/10.1021/jp050469m
Duan, Wenyong, et al. "Three-dimensional morphological chirality induction using high magnetic fields in membrane tubes prepared by a silicate garden reaction." The journal of physical chemistry. B vol. 109,28 (2005): 13445-50. doi: https://doi.org/10.1021/jp050469m
Duan W, Kitamura S, Uechi I, Katsuki A, Tanimoto Y. Three-dimensional morphological chirality induction using high magnetic fields in membrane tubes prepared by a silicate garden reaction. J Phys Chem B. 2005 Jul 21;109(28):13445-50. doi: 10.1021/jp050469m. PMID: 16852682.
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Serum Levels of Brain-Derived Neurotrophic Factor at 4 Weeks and Response to Treatment with SSRIs.

Psychiatry investigation

Yoshimura R, Kishi T, Hori H, Katsuki A, Sugita-Ikenouchi A, Umene-Nakano W, Atake K, Iwata N, Nakamura J.
PMID: 24605128
Psychiatry Investig. 2014 Jan;11(1):84-8. doi: 10.4306/pi.2014.11.1.84. Epub 2014 Jan 21.

OBJECTIVE: It is important to predict a response to an antidepressant in early time after starting the antidepressant. We previously reported that serum brain-derived neurotrophic factor (BDNF) levels in responders to treatment with antidepressants were increased, whereas, those in...

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Yoshimura R, Kishi T, Hori H, et al. Serum Levels of Brain-Derived Neurotrophic Factor at 4 Weeks and Response to Treatment with SSRIs. Psychiatry Investig. 2014;11(1):84-8doi: 10.4306/pi.2014.11.1.84.
Yoshimura, R., Kishi, T., Hori, H., Katsuki, A., Sugita-Ikenouchi, A., Umene-Nakano, W., Atake, K., Iwata, N., & Nakamura, J. (2014). Serum Levels of Brain-Derived Neurotrophic Factor at 4 Weeks and Response to Treatment with SSRIs. Psychiatry investigation, 11(1), 84-8. https://doi.org/10.4306/pi.2014.11.1.84
Yoshimura, Reiji, et al. "Serum Levels of Brain-Derived Neurotrophic Factor at 4 Weeks and Response to Treatment with SSRIs." Psychiatry investigation vol. 11,1 (2014): 84-8. doi: https://doi.org/10.4306/pi.2014.11.1.84
Yoshimura R, Kishi T, Hori H, Katsuki A, Sugita-Ikenouchi A, Umene-Nakano W, Atake K, Iwata N, Nakamura J. Serum Levels of Brain-Derived Neurotrophic Factor at 4 Weeks and Response to Treatment with SSRIs. Psychiatry Investig. 2014 Jan;11(1):84-8. doi: 10.4306/pi.2014.11.1.84. Epub 2014 Jan 21. PMID: 24605128; PMCID: PMC3942556.
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Whole-genome profiling highlights the molecular complexity underlying eccentric cardiac hypertrophy.

Therapeutic advances in cardiovascular disease

Barnes J, Pat B, Chen YW, Powell PC, Bradley WE, Zheng J, Karki A, Cui X, Guichard J, Wei CC, Collawn J, Dell'Italia LJ.
PMID: 24692245
Ther Adv Cardiovasc Dis. 2014 Jun 01;8(3):97-118. doi: 10.1177/1753944714527490. Epub 2014 Mar 31.

OBJECTIVES: Heart failure is typically preceded by myocardial hypertrophy and remodeling, which can be concentric due to pressure overload (PO), or eccentric because of volume overload (VO). The molecular mechanisms that underlie these differing patterns of hypertrophy are distinct...

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Barnes J, Pat B, Chen YW, et al. Whole-genome profiling highlights the molecular complexity underlying eccentric cardiac hypertrophy. Ther Adv Cardiovasc Dis. 2014;8(3):97-118doi: 10.1177/1753944714527490.
Barnes, J., Pat, B., Chen, Y. W., Powell, P. C., Bradley, W. E., Zheng, J., Karki, A., Cui, X., Guichard, J., Wei, C. C., Collawn, J., & Dell'Italia, L. J. (2014). Whole-genome profiling highlights the molecular complexity underlying eccentric cardiac hypertrophy. Therapeutic advances in cardiovascular disease, 8(3), 97-118. https://doi.org/10.1177/1753944714527490
Barnes, Justin, et al. "Whole-genome profiling highlights the molecular complexity underlying eccentric cardiac hypertrophy." Therapeutic advances in cardiovascular disease vol. 8,3 (2014): 97-118. doi: https://doi.org/10.1177/1753944714527490
Barnes J, Pat B, Chen YW, Powell PC, Bradley WE, Zheng J, Karki A, Cui X, Guichard J, Wei CC, Collawn J, Dell'Italia LJ. Whole-genome profiling highlights the molecular complexity underlying eccentric cardiac hypertrophy. Ther Adv Cardiovasc Dis. 2014 Jun 01;8(3):97-118. doi: 10.1177/1753944714527490. Epub 2014 Mar 31. PMID: 24692245.
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Cognitive insight and functional outcome in schizophrenia; a multi-center collaborative study with the specific level of functioning scale-Japanese version.

Schizophrenia research. Cognition

Sumiyoshi T, Nishida K, Niimura H, Toyomaki A, Morimoto T, Tani M, Inada K, Ninomiya T, Hori H, Manabe J, Katsuki A, Kubo T, Koshikawa Y, Shirahama M, Kohno K, Kinoshita T, Kusumi I, Iwanami A, Ueno T, Kishimoto T, Terao T, Nakagome K.
PMID: 28740819
Schizophr Res Cogn. 2016 Sep 28;6:9-14. doi: 10.1016/j.scog.2016.08.001. eCollection 2016 Dec.

The Specific Levels of Functioning Scale (SLOF) has been reported to provide a measure of social function in patients with schizophrenia. The aim of this multi-center study was to determine convergent validity of the Japanese version of SLOF, and...

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Sumiyoshi T, Nishida K, Niimura H, et al. Cognitive insight and functional outcome in schizophrenia; a multi-center collaborative study with the specific level of functioning scale-Japanese version. Schizophr Res Cogn. 2016;6:9-14doi: 10.1016/j.scog.2016.08.001.
Sumiyoshi, T., Nishida, K., Niimura, H., Toyomaki, A., Morimoto, T., Tani, M., Inada, K., Ninomiya, T., Hori, H., Manabe, J., Katsuki, A., Kubo, T., Koshikawa, Y., Shirahama, M., Kohno, K., Kinoshita, T., Kusumi, I., Iwanami, A., Ueno, T., Kishimoto, T., Terao, T., & Nakagome, K. (2016). Cognitive insight and functional outcome in schizophrenia; a multi-center collaborative study with the specific level of functioning scale-Japanese version. Schizophrenia research. Cognition, 69-14. https://doi.org/10.1016/j.scog.2016.08.001
Sumiyoshi, Tomiki, et al. "Cognitive insight and functional outcome in schizophrenia; a multi-center collaborative study with the specific level of functioning scale-Japanese version." Schizophrenia research. Cognition vol. 6 (2016): 9-14. doi: https://doi.org/10.1016/j.scog.2016.08.001
Sumiyoshi T, Nishida K, Niimura H, Toyomaki A, Morimoto T, Tani M, Inada K, Ninomiya T, Hori H, Manabe J, Katsuki A, Kubo T, Koshikawa Y, Shirahama M, Kohno K, Kinoshita T, Kusumi I, Iwanami A, Ueno T, Kishimoto T, Terao T, Nakagome K. Cognitive insight and functional outcome in schizophrenia; a multi-center collaborative study with the specific level of functioning scale-Japanese version. Schizophr Res Cogn. 2016 Sep 28;6:9-14. doi: 10.1016/j.scog.2016.08.001. eCollection 2016 Dec. PMID: 28740819; PMCID: PMC5514305.
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Doping effect on the physical properties of Ca.

Journal of physics. Condensed matter : an Institute of Physics journal

Pan J, Karki A, Plummer EW, Jin R.
PMID: 29120865
J Phys Condens Matter. 2017 Dec 06;29(48):485702. doi: 10.1088/1361-648X/aa958f. Epub 2017 Nov 09.

Ca

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Pan J, Karki A, Plummer EW, et al. Doping effect on the physical properties of Ca. J Phys Condens Matter. 2017;29(48):485702doi: 10.1088/1361-648X/aa958f.
Pan, J., Karki, A., Plummer, E. W., & Jin, R. (2017). Doping effect on the physical properties of Ca. Journal of physics. Condensed matter : an Institute of Physics journal, 29(48), 485702. https://doi.org/10.1088/1361-648X/aa958f
Pan, Jiayun, et al. "Doping effect on the physical properties of Ca." Journal of physics. Condensed matter : an Institute of Physics journal vol. 29,48 (2017): 485702. doi: https://doi.org/10.1088/1361-648X/aa958f
Pan J, Karki A, Plummer EW, Jin R. Doping effect on the physical properties of Ca. J Phys Condens Matter. 2017 Dec 06;29(48):485702. doi: 10.1088/1361-648X/aa958f. Epub 2017 Nov 09. PMID: 29120865.
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