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Showing 1 to 12 of 17 entries
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Erratum to: 'Emerging pan-resistance in Trichosporon species: a case report'.

BMC infectious diseases

Dos Santos CO, Zijlstra JG, Porte RJ, Kampinga GA, van Diepeningen AD, Sinha B, Bathoorn E.
PMID: 27289355
BMC Infect Dis. 2016 Jun 11;16(1):279. doi: 10.1186/s12879-016-1621-0.

No abstract available.

Efficacy of Antibiotic Suppressive Therapy in Patients with a Prosthetic Joint Infection.

Journal of bone and joint infection

Wouthuyzen-Bakker M, Nijman JM, Kampinga GA, van Assen S, Jutte PC.
PMID: 28529867
J Bone Jt Infect. 2017 Jan 15;2(2):77-83. doi: 10.7150/jbji.17353. eCollection 2017.

No abstract available.

Interaction between the cytostatic effects of quercetin and 5-fluorouracil in two human colorectal cancer cell lines.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Boersma HH, Woerdenbag HJ, Bauer J, Scheithauer W, Kampinga HH, Konings AW.
PMID: 23195945
Phytomedicine. 1994 Dec;1(3):239-44. doi: 10.1016/S0944-7113(11)80071-1.

Therapy with 5-fluorouracil (5-FU) as a single agent has only limited success in palliative treatment of cancer of the large bowel. In the current study, the effect of quercetin on the action of 5-FU in the human colorectal cancer...

DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in .

iScience

Joshi BS, Youssef SA, Bron R, de Bruin A, Kampinga HH, Zuhorn IS.
PMID: 34755099
iScience. 2021 Oct 14;24(11):103282. doi: 10.1016/j.isci.2021.103282. eCollection 2021 Nov 19.

Huntington disease (HD) is a devastating neurodegenerative disorder characterized by aggregation of huntingtin (HTT) protein containing expanded polyglutamine (polyQ) tracts. DNAJB6, a member of the DNAJ chaperone family, was reported to efficiently inhibit polyQ aggregation

FOXO1 controls protein synthesis and transcript abundance of mutant polyglutamine proteins, preventing protein aggregation.

Human molecular genetics

Furtado GV, Yang J, Wu D, Papagiannopoulos CI, Terpstra HM, Kuiper EFE, Krauss S, Zhu WG, Kampinga HH, Bergink S.
PMID: 33822053
Hum Mol Genet. 2021 May 31;30(11):996-1005. doi: 10.1093/hmg/ddab095.

FOXO1, a transcription factor downstream of the insulin/insulin like growth factor axis, has been linked to protein degradation. Elevated expression of FOXO orthologs can also prevent the aggregation of cytosine adenine guanine (CAG)-repeat disease causing polyglutamine (polyQ) proteins but...

Thrombus Aspiration during Percutaneous coronary intervention in Acute non-ST-elevation myocardial infarction Study (TAPAS II)-Study design.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Kampinga MA, Vlaar PJ, Fokkema M, Gu YL, Zijlstra F.
PMID: 19949708
Neth Heart J. 2009 Nov;17(11):409-13. doi: 10.1007/BF03086293.

Background and Objective. The Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS) has shown that thrombus aspiration improves myocardial perfusion and clinical outcome compared with conventional primary percutaneous coronary intervention (PCI) in patients with ST-segment-elevation...

DNAJs: more than substrate delivery to HSPA.

Frontiers in molecular biosciences

Dekker SL, Kampinga HH, Bergink S.
PMID: 26176011
Front Mol Biosci. 2015 Jun 30;2:35. doi: 10.3389/fmolb.2015.00035. eCollection 2015.

Proteins are essential components of cellular life, as building blocks, but also to guide and execute all cellular processes. Proteins require a three-dimensional folding, which is constantly being challenged by their environment. Challenges including elevated temperatures or redox changes...

Absence of Host-Specific Genes in Canine and Human .

Antibiotics (Basel, Switzerland)

Wegener A, Broens EM, van der Graaf-van Bloois L, Zomer AL, Visser CE, van Zeijl J, van der Meer C, Kusters JG, Friedrich AW, Kampinga GA, Sips GJ, Smeets L, van Kerckhoven MEJ, Timmerman AJ, Wagenaar JA, Duim B.
PMID: 34356775
Antibiotics (Basel). 2021 Jul 14;10(7). doi: 10.3390/antibiotics10070854.

No abstract available.

Whole-genome sequence-informed MALDI-TOF MS diagnostics reveal importance of Klebsiella oxytoca group in invasive infections: a retrospective clinical study.

Genome medicine

Cuénod A, Wüthrich D, Seth-Smith HMB, Ott C, Gehringer C, Foucault F, Mouchet R, Kassim A, Revathi G, Vogt DR, von Felten S, Bassetti S, Tschudin-Sutter S, Hettich T, Schlotterbeck G, Homberger C, Casanova C, Moran-Gilad J, Sagi O, Rodríguez-Sánchez B, Müller F, Aerni M, Gaia V, van Dessel H, Kampinga GA, Müller C, Daubenberger C, Pflüger V, Egli A.
PMID: 34517886
Genome Med. 2021 Sep 13;13(1):150. doi: 10.1186/s13073-021-00960-5.

BACKGROUND: Klebsiella spp. are opportunistic pathogens which can cause severe infections, are often multi-drug resistant and are a common cause of hospital-acquired infections. Multiple new Klebsiella species have recently been described, yet their clinical impact and antibiotic resistance profiles...

Drosophila phosphopantothenoylcysteine synthetase is required for tissue morphogenesis during oogenesis.

BMC research notes

Bosveld F, Rana A, Lemstra W, Kampinga HH, Sibon OC.
PMID: 18759961
BMC Res Notes. 2008 Aug 29;1:75. doi: 10.1186/1756-0500-1-75.

BACKGROUND: Coenzyme A (CoA) is an essential metabolite, synthesized from vitamin B5 by the subsequent action of five enzymes: PANK, PPCS, PPCDC, PPAT and DPCK. Mutations in Drosophila dPPCS disrupt female fecundity and in this study we analyzed the...

Chaperones in Polyglutamine Aggregation: Beyond the Q-Stretch.

Frontiers in neuroscience

Kuiper EF, de Mattos EP, Jardim LB, Kampinga HH, Bergink S.
PMID: 28386214
Front Neurosci. 2017 Mar 23;11:145. doi: 10.3389/fnins.2017.00145. eCollection 2017.

Expanded polyglutamine (polyQ) stretches in at least nine unrelated proteins lead to inherited neuronal dysfunction and degeneration. The expansion size in all diseases correlates with age at onset (AO) of disease and with polyQ protein aggregation, indicating that the...

Epidemiology of Extended-Spectrum β-Lactamase-Producing .

Frontiers in microbiology

Zhou X, García-Cobos S, Ruijs GJHM, Kampinga GA, Arends JP, Borst DM, Möller LV, Holman ND, Schuurs TA, Bruijnesteijn van Coppenraet LE, Weel JF, van Zeijl JH, Köck R, Rossen JWA, Friedrich AW.
PMID: 29051750
Front Microbiol. 2017 Oct 05;8:1914. doi: 10.3389/fmicb.2017.01914. eCollection 2017.

No abstract available.

Showing 1 to 12 of 17 entries