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Showing 1 to 12 of 317 entries
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Characterization of coronary atherosclerosis by intravascular imaging modalities.

Cardiovascular diagnosis and therapy

Honda S, Kataoka Y, Kanaya T, Noguchi T, Ogawa H, Yasuda S.
PMID: 27500094
Cardiovasc Diagn Ther. 2016 Aug;6(4):368-81. doi: 10.21037/cdt.2015.12.05.

Coronary artery disease (CAD) is highly prevalent in Western countries and is associated with morbidity, mortality, and a significant economic burden. Despite the development of anti-atherosclerotic medical therapies, many patients still continue to suffer from coronary events. This residual...

The Mechanisms of M-cell Differentiation.

Bioscience of microbiota, food and health

Kanaya T, Ohno H.
PMID: 25032083
Biosci Microbiota Food Health. 2014;33(3):91-7. doi: 10.12938/bmfh.33.91. Epub 2014 May 09.

Intestinal M (microfold or membranous) cells are an enigmatic lineage of intestinal epithelial cells that initiate mucosal immune responses through the uptake and transcytosis of luminal antigens. Due to their rarity, the mechanisms of M-cell function and differentiation are...

The influence of pioglitazone on the plasma amino acid profile in patients with nonalcoholic steatohepatitis (NASH).

Hepatology international

Kakazu E, Kondo Y, Ninomiya M, Kimura O, Nagasaki F, Ueno Y, Shimosegawa T.
PMID: 26201790
Hepatol Int. 2013 Jun;7(2):577-85. doi: 10.1007/s12072-012-9395-y. Epub 2012 Aug 14.

BACKGROUND AND AIMS: The peroxisome proliferator-activated receptor-γ (PPAR-γ) ligand, piglitazone, enhances the degradation of branched-chain amino acids (BCAAs) in adipose tissue. However, it remains unknown whether pioglitazone influences the plasma amino acids (AA) profile in patients with nonalcoholic steatohepatitis...

Functional polymer-dependent 3D culture accelerates the differentiation of HepaRG cells into mature hepatocytes.

Hepatology research : the official journal of the Japan Society of Hepatology

Higuchi Y, Kawai K, Kanaki T, Yamazaki H, Chesné C, Guguen-Guillouzo C, Suemizu H.
PMID: 26724677
Hepatol Res. 2016 Sep;46(10):1045-57. doi: 10.1111/hepr.12644. Epub 2016 Feb 07.

AIM: The hepatoma-derived cell line HepaRG is regarded as an in vitro model of drug metabolism because fully differentiated HepaRG cells demonstrate functional metabolic responses comparable to those of primary human hepatocytes. Recently, it was demonstrated that the 3D...

Quasielastic neutron scattering study of microscopic dynamics in polybutadiene reinforced with an unsaturated carboxylate.

Soft matter

Mashita R, Inoue R, Tominaga T, Shibata K, Kishimoto H, Kanaya T.
PMID: 29019368
Soft Matter. 2017 Nov 08;13(43):7862-7869. doi: 10.1039/c7sm01262d.

We studied the dynamics of zinc diacrylate (ZDA) reinforced polybutadiene rubber (BR) (ZDA/BR) using the quasielastic neutron scattering technique to determine the effect of concentration of ZDA on polymer dynamics. First, we evaluated the temperature dependence of mean square...

Effect of baseline HbA1c level on the development of diabetes by lifestyle intervention in primary healthcare settings: insights from subanalysis of the Japan Diabetes Prevention Program.

BMJ open diabetes research & care

Sakane N, Sato J, Tsushita K, Tsujii S, Kotani K, Tominaga M, Kawazu S, Sato Y, Usui T, Kamae I, Yoshida T, Kiyohara Y, Sato S, Tsuzaki K, Takahashi K, Kuzuya H.
PMID: 25452854
BMJ Open Diabetes Res Care. 2014 Apr 23;2(1):e000003. doi: 10.1136/bmjdrc-2013-000003. eCollection 2014.

OBJECTIVES: To determine the effects of a lifestyle intervention on the development of type 2 diabetes mellitus (T2DM) among participants with impaired glucose tolerance (IGT), in particular in the subgroup with baseline glycated hemoglobin (HbA1c) levels ≥5.7%, in primary...

Identification of Four Novel Synonymous Substitutions in the X-Linked Genes Neuroligin 3 and Neuroligin 4X in Japanese Patients with Autistic Spectrum Disorder.

Autism research and treatment

Yanagi K, Kaname T, Wakui K, Hashimoto O, Fukushima Y, Naritomi K.
PMID: 22934180
Autism Res Treat. 2012;2012:724072. doi: 10.1155/2012/724072. Epub 2012 Jul 16.

Mutations in the X-linked genes neuroligin 3 (NLGN3) and neuroligin 4X (NLGN4X) were first implicated in the pathogenesis of X-linked autism in Swedish families. However, reports of mutations in these genes in autism spectrum disorder (ASD) patients from various...

Leiomyosarcoma of the retrohepatic vena cava: Report of a case treated with resection and reconstruction with polytetrafluoroethylene vascular graft.

Ulusal cerrahi dergisi

Yankol Y, Mecit N, Kanmaz T, Acarlı K.
PMID: 26504421
Ulus Cerrahi Derg. 2015 Jun 19;31(3):162-5. doi: 10.5152/UCD.2015.2882. eCollection 2015.

Leiomyosarcoma of the vena cava is a rare malignant tumor. A 61-year-old woman was admitted with right upper quadrant abdominal pain. Computed tomography revealed a retrohepatic vena cava tumor originating 2 cm below the confluence of the hepaic veins...

Linking uric acid metabolism to diabetic complications.

World journal of diabetes

Kushiyama A, Tanaka K, Hara S, Kawazu S.
PMID: 25512781
World J Diabetes. 2014 Dec 15;5(6):787-95. doi: 10.4239/wjd.v5.i6.787.

Hyperuricemia have been thought to be caused by the ingestion of large amounts of purines, and prevention or treatment of hyperuricemia has intended to prevent gout. Xanthine dehydrogenase/xanthine oxidase (XDH/XO) is rate-limiting enzyme of uric acid generation, and allopurinol...

Prenatal diagnosis of isolated atrioventricular discordance using fetal echocardiography.

Images in paediatric cardiology

Kanagawa N, Inamura N, Narita J, Kawazu Y, Kayatani F.
PMID: 26236366
Images Paediatr Cardiol. 2014 Jan-Mar;16(1):5-10.

No abstract available.

Low-energy excitations and the fast process of polystyrene thin supported films studied by inelastic and quasielastic neutron scattering.

Physical review. E, Statistical, nonlinear, and soft matter physics

Inoue R, Kanaya T, Nishida K, Tsukushi I, Shibata K.
PMID: 17025460
Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Aug;74(2):021801. doi: 10.1103/PhysRevE.74.021801. Epub 2006 Aug 03.

We studied the low-energy excitations in the meV region as well as the picosecond fast process in polystyrene thin supported films using inelastic and quasielastic neutron scattering in a temperature range from 11 to 430 K , covering the...

s-Myc acts as a transcriptional activator and its sequence-specific DNA binding is required for induction of programmed cell death in glioma cells.

Cell death and differentiation

Kitanaka C, Sugiyama A, Kanazu S, Miyagi Y, Mishima K, Asai A, Kuchino Y.
PMID: 17180074
Cell Death Differ. 1995 Apr;2(2):123-31.

We previously reported that s-Myc expression effectively induces programmed cell death (PCD) by apoptosis in glioma cells that express only mutated p53. To determine the molecular mechanism of s-Myc-induced PCD, we examined the correlation between transcriptional activation of s-Myc...

Showing 1 to 12 of 317 entries