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Showing 1 to 11 of 11 entries
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Preliminary Observations on the Use of .

The Indian medical gazette

Gupta JC, Deb AK, Kahali BS.
PMID: 29012151
Ind Med Gaz. 1943 Nov;78(11):547-549.

No abstract available.

Subchronic exposure to phytoestrogens alone and in combination with diethylstilbestrol - pituitary tumor induction in Fischer 344 rats.

Nutrition & metabolism

Jeng YJ, Kochukov M, Nauduri D, Kaphalia BS, Watson CS.
PMID: 20459739
Nutr Metab (Lond). 2010 May 10;7:40. doi: 10.1186/1743-7075-7-40.

BACKGROUND: Subchronic administration of the potent pharmaceutical estrogen diethylstilbestrol (DES) to female Fischer 344 (F344) rats induces growth of large, hemorrhagic pituitaries that progress to tumors. Phytoestrogens (dietary plant estrogens) are hypothesized to be potential tumor inhibitors in tissues...

Exposure to binge ethanol and fatty acid ethyl esters exacerbates chronic ethanol-induced pancreatic injury in hepatic alcohol dehydrogenase deficient deer mice.

American journal of physiology. Gastrointestinal and liver physiology

Srinivasan MP, Bhopale KK, Caracheo AA, Kaphalia L, Gong B, Popov VL, Boor PJ, Shakeel Ansari GA, Kaphalia BS.
PMID: 34984929
Am J Physiol Gastrointest Liver Physiol. 2022 Jan 05; doi: 10.1152/ajpgi.00263.2021. Epub 2022 Jan 05.

Alcoholic chronic pancreatitis (ACP) is a fibroinflammatory disease of the pancreas. However, metabolic basis of ACP is not clearly understood. In this study, we evaluated differential pancreatic injury in hepatic alcohol dehydrogenase deficient (ADH

Alcohol-Induced Hepatic Steatosis: A Comparative Study to Identify Possible Indicator(s) of Alcoholic Fatty Liver Disease.

Journal of drug and alcohol research

Fernando H, Bhopale KK, Kondraganti SS, Kaphalia BS, Ansari GAS.
PMID: 31032137
J Drug Alcohol Res. 2018;7. doi: 10.4303/jdar/236040. Epub 2018 Jan 01.

BACKGROUND: Fatty liver is an early sign of both nonalcoholic and alcoholic fatty liver diseases. Ethanol feeding using a Lieber-DeCarli liquid diet (LD) model which contains 35% fat to rats or mice is a well-established model for alcoholic fatty...

The Indian medical gazette

Gupta JC, Kahali BS, Ganguly SC.
PMID: 29012957
Ind Med Gaz. 1942 Dec;77(12):721-723.

No abstract available.

Differential cytotoxicity, ER/oxidative stress, dysregulated AMPKα signaling, and mitochondrial stress by ethanol and its metabolites in human pancreatic acinar cells.

Alcoholism, clinical and experimental research

Srinivasan MP, Bhopale KK, Caracheo AA, Kaphalia L, Loganathan G, Balamurugan AN, Rastellini C, Kaphalia BS.
PMID: 33690904
Alcohol Clin Exp Res. 2021 May;45(5):961-978. doi: 10.1111/acer.14595. Epub 2021 Apr 02.

BACKGROUND: Alcoholic chronic pancreatitis (ACP) is a serious inflammatory disorder of the exocrine pancreatic gland. A previous study from this laboratory showed that ethanol (EtOH) causes cytotoxicity, dysregulates AMPKα and ER/oxidative stress signaling, and induces inflammatory responses in primary...

Immunotoxic response of oleic acid anilide and its hydrolysis products in female MRL (+/+) mice.

Journal of immunotoxicology

Cai P, Khan MF, Kaphalia BS, Ansari GA.
PMID: 18958679
J Immunotoxicol. 2005 Oct 01;2(4):231-6. doi: 10.1080/15476910500362960.

An epidemic of a multi-systemic disease, known as the toxic oil syndrome (TOS), was caused by consumption of edible oil denatured with 2% aniline. Oleic acid anilide (OAA) has been suggested as one of the most likely etiologic agents...

Immuno- and hepato-toxicity of dichloroacetic acid in MRL(+/+) and B(6)C(3)F(1) mice.

Journal of immunotoxicology

Cai P, Boor PJ, Khan MF, Kaphalia BS, Ansari GA, Konig R.
PMID: 18958719
J Immunotoxicol. 2007 Apr;4(2):107-15. doi: 10.1080/15476910701337225.

Dichloroacetic acid (DCA) is a by-product of chlorination that occurs in drinking water disinfected with chlorine. Metabolism of trichloroethene (TCE) also generates DCA. TCE exposure is associated with the development of autoimmune diseases, which may be induced by TCE...

The water disinfectant byproduct dibromoacetonitrile induces apoptosis in rat intestinal epithelial cells: possible role of redox imbalance.

Toxicology mechanisms and methods

Jacob S, Kaphalia BS, Jacob N, Ahmed AE.
PMID: 20021047
Toxicol Mech Methods. 2006;16(4):227-34. doi: 10.1080/15376520600626239.

Chemically induced oxidative stress poses cytotoxic effects on intestinal epithelial cells that may trigger various forms of injuries in intestinal mucosa. Haloacetonitriles, including dibromoacetonitrile (DBAN, a drinking water contaminant and direct acting mutagen and carcinogen), are known to induce...

Alcoholic Steatosis in Different Strains of Rat: A Comparative Study.

Journal of drug and alcohol research

Bhopale KK, Kondraganti S, Fernando H, Boor PJ, Kaphalia BS, Shakeel Ansari GA.
PMID: 27213081
J Drug Alcohol Res. 2015;4. doi: 10.4303/jdar/235912. Epub 2015 May 25.

BACKGROUND: Different strains of rats have been used to study alcoholic liver disease (ALD) while the reason for selecting a particular rat strain was not apparent.PURPOSE: The aim of our study was to compare outbred (Wistar) and inbred (Fischer)...

Adult Hæmoglobin Standards in Burma.

The Indian medical gazette

Cropper CFJ, Kahali BS.
PMID: 29014166
Ind Med Gaz. 1938 Mar;73(3):139-140.

No abstract available.

Showing 1 to 11 of 11 entries