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Showing 1 to 12 of 30 entries
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Double-blind acupuncture needle: a potential tool to investigate the nature of pain and pleasure.

ISRN Pain

Takakura N, Takayama M, Kawase A, Kaptchuk TJ, Yajima H.
PMID: 24288658
ISRN Pain. 2013;2013. doi: 10.1155/2013/825751.

BACKGROUND: Most of our knowledge about similarities in the neural processing of painful and pleasant sensations in the brain derives from studying each phenomenon separately. Patients often feel pain induced by acupuncture, which is noxious stimulation having the symbolic...

Network analysis of the genomic basis of the placebo effect.

JCI insight

Wang RS, Hall KT, Giulianini F, Passow D, Kaptchuk TJ, Loscalzo J.
PMID: 28570268
JCI Insight. 2017 Jun 02;2(11). doi: 10.1172/jci.insight.93911. eCollection 2017 Jun 02.

The placebo effect is a phenomenon in which patients who are given an inactive treatment (e.g., inert pill) show a perceived or actual improvement in a medical condition. Placebo effects in clinical trials have been investigated for many years...

Distant healing.

Annals of internal medicine

Kaptchuk TJ.
PMID: 11255536
Ann Intern Med. 2001 Mar 20;134(6):532-3. doi: 10.7326/0003-4819-134-6-200103200-00025.

No abstract available.

Structural integration as an adjunct to outpatient rehabilitation for chronic nonspecific low back pain: a randomized pilot clinical trial.

Evidence-based complementary and alternative medicine : eCAM

Jacobson EE, Meleger AL, Bonato P, Wayne PM, Langevin HM, Kaptchuk TJ, Davis RB.
PMID: 25945112
Evid Based Complement Alternat Med. 2015;2015:813418. doi: 10.1155/2015/813418. Epub 2015 Apr 07.

Structural Integration (SI) is an alternative method of manipulation and movement education. To obtain preliminary data on feasibility, effectiveness, and adverse events (AE), 46 outpatients from Boston area with chronic nonspecific low back pain (CNSLBP) were randomized to parallel...

Author Correction: Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain.

Nature communications

Tu Y, Fu Z, Mao C, Falahpour M, Gollub RL, Park J, Wilson G, Napadow V, Gerber J, Chan ST, Edwards RR, Kaptchuk TJ, Liu T, Calhoun V, Rosen B, Kong J.
PMID: 32843661
Nat Commun. 2020 Aug 25;11(1):4347. doi: 10.1038/s41467-020-18191-4.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

"Honorable Toward Your Whole Self": Experiences of the Body in Fatigued Breast Cancer Survivors.

Frontiers in psychology

Penner C, Zimmerman C, Conboy L, Kaptchuk T, Kerr C.
PMID: 32719641
Front Psychol. 2020 Jul 03;11:1502. doi: 10.3389/fpsyg.2020.01502. eCollection 2020.

INTRODUCTION: Cancer Related Fatigue (CRF) is one of the most common and detrimental side effects of cancer treatment. Despite its increasing prevalence and severity CRF remains dismissed by the majority of clinicians. One reason for the apparent gap between...

Improving Medication Tolerance: A Pilot Study in Disorders of Gut-brain Interaction Treated With Tricyclic Antidepressants.

Journal of clinical gastroenterology

Ballou S, Iturrino J, Rangan V, Cheng V, Kelley JM, Lembo A, Kaptchuk TJ, Nee J.
PMID: 34091518
J Clin Gastroenterol. 2021 Jun 07; doi: 10.1097/MCG.0000000000001575. Epub 2021 Jun 07.

OBJECTIVES: Tricyclic antidepressants (TCAs) are commonly used to treat disorders of gut-brain interaction (DGBI). However, these medications are often associated with side effects that lead to early treatment discontinuation. Research in other chronic medical conditions suggests that many TCA...

Frequency of Adverse Events in the Placebo Arms of COVID-19 Vaccine Trials: A Systematic Review and Meta-analysis.

JAMA network open

Haas JW, Bender FL, Ballou S, Kelley JM, Wilhelm M, Miller FG, Rief W, Kaptchuk TJ.
PMID: 35040967
JAMA Netw Open. 2022 Jan 04;5(1):e2143955. doi: 10.1001/jamanetworkopen.2021.43955.

IMPORTANCE: Adverse events (AEs) after placebo treatment are common in randomized clinical drug trials. Systematic evidence regarding these nocebo responses in vaccine trials is important for COVID-19 vaccination worldwide especially because concern about AEs is reported to be a...

Manipulating placebo analgesia and nocebo hyperalgesia by changing brain excitability.

Proceedings of the National Academy of Sciences of the United States of America

Tu Y, Wilson G, Camprodon J, Dougherty DD, Vangel M, Benedetti F, Kaptchuk TJ, Gollub RL, Kong J.
PMID: 33941677
Proc Natl Acad Sci U S A. 2021 May 11;118(19). doi: 10.1073/pnas.2101273118.

Harnessing placebo and nocebo effects has significant implications for research and medical practice. Placebo analgesia and nocebo hyperalgesia, the most well-studied placebo and nocebo effects, are thought to initiate from the dorsal lateral prefrontal cortex (DLPFC) and then trigger...

A 4-Month Whole-Systems Ayurvedic Medicine Nutrition and Lifestyle Intervention Is Feasible and Acceptable for Breast Cancer Survivors: Results of a Single-Arm Pilot Clinical Trial.

Global advances in health and medicine

Dhruva A, Wu C, Miaskowski C, Hartogensis W, Rugo HS, Adler SR, Kaptchuk TJ, Kelkar R, Agarawal S, Vadodaria A, Garris E, Hecht FM.
PMID: 33312762
Glob Adv Health Med. 2020 Dec 01;9:2164956120964712. doi: 10.1177/2164956120964712. eCollection 2020.

PURPOSE: Ongoing symptoms and impairments in quality of life (QOL) among breast cancer survivors remain a significant problem. We tested the feasibility and acceptability of a manualized Ayurvedic nutrition and lifestyle intervention for breast cancer survivors.METHODS: Eligible participants had...

In the name of medicine.

Annals of internal medicine

Kaptchuk TJ.
PMID: 9758588
Ann Intern Med. 1998 Oct 01;129(7):589. doi: 10.7326/0003-4819-129-7-199810010-00022.

No abstract available.

Conditioning open-label placebo: a pilot pharmacobehavioral approach for opioid dose reduction and pain control.

Pain reports

Morales-Quezada L, Mesia-Toledo I, Estudillo-Guerra A, O'Connor KC, Schneider JC, Sohn DJ, Crandell DM, Kaptchuk T, Zafonte R.
PMID: 32766465
Pain Rep. 2020 Jul 20;5(4):e828. doi: 10.1097/PR9.0000000000000828. eCollection 2020.

Opioid consumption for those in comprehensive inpatient rehabilitation units is high because of the complexity of their injuries. Notably, pain in rehabilitation leads to worsened clinical outcomes because of maladaptive behaviors and poor engagement during therapies. It is critical...

Showing 1 to 12 of 30 entries