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Showing 1 to 12 of 58 entries
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CheS-Mapper - Chemical Space Mapping and Visualization in 3D.

Journal of cheminformatics

Gütlein M, Karwath A, Kramer S.
PMID: 22424447
J Cheminform. 2012 Mar 17;4(1):7. doi: 10.1186/1758-2946-4-7.

Analyzing chemical datasets is a challenging task for scientific researchers in the field of chemoinformatics. It is important, yet difficult to understand the relationship between the structure of chemical compounds, their physico-chemical properties, and biological or toxic effects. To...

Collaborative development of predictive toxicology applications.

Journal of cheminformatics

Hardy B, Douglas N, Helma C, Rautenberg M, Jeliazkova N, Jeliazkov V, Nikolova I, Benigni R, Tcheremenskaia O, Kramer S, Girschick T, Buchwald F, Wicker J, Karwath A, Gütlein M, Maunz A, Sarimveis H, Melagraki G, Afantitis A, Sopasakis P, Gallagher D, Poroikov V, Filimonov D, Zakharov A, Lagunin A, Gloriozova T, Novikov S, Skvortsova N, Druzhilovsky D, Chawla S, Ghosh I, Ray S, Patel H, Escher S.
PMID: 20807436
J Cheminform. 2010 Aug 31;2(1):7. doi: 10.1186/1758-2946-2-7.

OpenTox provides an interoperable, standards-based Framework for the support of predictive toxicology data management, algorithms, modelling, validation and reporting. It is relevant to satisfying the chemical safety assessment requirements of the REACH legislation as it supports access to experimental...

Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater

Karwautz A.
PMID: 30838632
Neuropsychiatr. 2019 Mar;33(1):56. doi: 10.1007/s40211-019-0306-5.

No abstract available.

Web-based indicated prevention of common mental disorders in university students in four European countries - Study protocol for a randomised controlled trial.

Internet interventions

Musiat P, Potterton R, Gordon G, Spencer L, Zeiler M, Waldherr K, Kuso S, Nitsch M, Adamcik T, Wagner G, Karwautz A, Ebert DD, Dodd A, Dooley B, Harrison A, Whitt E, Haselgrove M, Sharpe H, Smith J, Tressler R, Troop N, Vinyard C, Görlich D, Beecham J, Bonin E, Jacobi C, Schmidt U.
PMID: 30775263
Internet Interv. 2018 Mar 15;16:35-42. doi: 10.1016/j.invent.2018.02.004. eCollection 2019 Apr.

BACKGROUND: Mental disorders and their symptoms are highly prevalent in the university student population, and the transition from secondary to tertiary education is associated with a rise in mental health problems. Existing web-based interventions for the prevention of common...

Redefining β-blocker response in heart failure patients with sinus rhythm and atrial fibrillation: a machine learning cluster analysis.

Lancet (London, England)

Karwath A, Bunting KV, Gill SK, Tica O, Pendleton S, Aziz F, Barsky AD, Chernbumroong S, Duan J, Mobley AR, Cardoso VR, Slater L, Williams JA, Bruce EJ, Wang X, Flather MD, Coats AJS, Gkoutos GV, Kotecha D.
PMID: 34474011
Lancet. 2021 Oct 16;398(10309):1427-1435. doi: 10.1016/S0140-6736(21)01638-X. Epub 2021 Aug 30.

BACKGROUND: Mortality remains unacceptably high in patients with heart failure and reduced left ventricular ejection fraction (LVEF) despite advances in therapeutics. We hypothesised that a novel artificial intelligence approach could better assess multiple and higher-dimension interactions of comorbidities, and...

Transition of a Collaborative In-Person Health Care Innovation Course to Online Learning.

The Journal of nursing education

Karwat A, Richmond TS, Leary M.
PMID: 34039139
J Nurs Educ. 2021 May;60(5):298-300. doi: 10.3928/01484834-20210420-12. Epub 2021 May 01.

BACKGROUND: As COVID-19 forced in-person courses to transition online, an active learning course focused on design thinking in health and health care embraced the challenge. Lessons learned, mistakes made, and thoughts on the future of online education in nursing...

Redefining β-blocker response in heart failure patients with sinus rhythm and atrial fibrillation: a machine learning cluster analysis.

Lancet (London, England)

Karwath A, Bunting KV, Gill SK, Tica O, Pendleton S, Aziz F, Barsky AD, Chernbumroong S, Duan J, Mobley AR, Cardoso VR, Slater L, Williams JA, Bruce EJ, Wang X, Flather MD, Coats AJS, Gkoutos GV, Kotecha D.
PMID: 34474011
Lancet. 2021 Oct 16;398(10309):1427-1435. doi: 10.1016/S0140-6736(21)01638-X. Epub 2021 Aug 30.

BACKGROUND: Mortality remains unacceptably high in patients with heart failure and reduced left ventricular ejection fraction (LVEF) despite advances in therapeutics. We hypothesised that a novel artificial intelligence approach could better assess multiple and higher-dimension interactions of comorbidities, and...

The 'Good European': A tribute to Fernando Fernandez-Aranda editor in chief of the European Eating Disorder review 2011-2021.

European eating disorders review : the journal of the Eating Disorders Association

Claes L, Favaro A, Karwautz A, Le Grange D, Tchanturia K, Treasure J.
PMID: 34668268
Eur Eat Disord Rev. 2021 Nov;29(6):985-986. doi: 10.1002/erv.2868. Epub 2021 Oct 19.

No abstract available.

Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater

Karwautz A.
PMID: 33306180
Neuropsychiatr. 2020 Dec;34(4):194-195. doi: 10.1007/s40211-020-00373-7.

No abstract available.

Effects of Negation and Uncertainty Stratification on Text-Derived Patient Profile Similarity.

Frontiers in digital health

Slater LT, Karwath A, Hoehndorf R, Gkoutos GV.
PMID: 34939069
Front Digit Health. 2021 Dec 06;3:781227. doi: 10.3389/fdgth.2021.781227. eCollection 2021.

Semantic similarity is a useful approach for comparing patient phenotypes, and holds the potential of an effective method for exploiting text-derived phenotypes for differential diagnosis, text and document classification, and outcome prediction. While approaches for context disambiguation are commonly...

The effects of probiotics administration on the gut microbiome in adolescents with anorexia nervosa-A study protocol for a longitudinal, double-blind, randomized, placebo-controlled trial.

European eating disorders review : the journal of the Eating Disorders Association

Gröbner EM, Zeiler M, Fischmeister FPS, Kollndorfer K, Schmelz S, Schneider A, Haid-Stecher N, Sevecke K, Wagner G, Keller L, Adan R, Danner U, van Elburg A, van der Vijgh B, Kooij KL, Fetissov S, Andreani NA, Baines JF, Dempfle A, Seitz J, Herpertz-Dahlmann B, Karwautz A.
PMID: 34851002
Eur Eat Disord Rev. 2022 Jan;30(1):61-74. doi: 10.1002/erv.2876. Epub 2021 Nov 30.

OBJECTIVE: Knowledge on gut-brain interaction might help to develop new therapies for patients with anorexia nervosa (AN), as severe starvation-induced changes of the microbiome (MI) do not normalise with weight gain. We examine the effects of probiotics supplementation on...

White matter integrity is disrupted in adolescents with acute anorexia nervosa: A diffusion tensor imaging study.

Psychiatry research. Neuroimaging

Laczkovics C, Nenning KH, Wittek T, Schmidbauer V, Schwarzenberg J, Maurer ES, Wagner G, Seidel S, Philipp J, Prayer D, Kasprian G, Karwautz A.
PMID: 34952446
Psychiatry Res Neuroimaging. 2021 Dec 11;320:111427. doi: 10.1016/j.pscychresns.2021.111427. Epub 2021 Dec 11.

Anorexia nervosa (AN) is a highly debilitating mental illness with multifactorial etiology. It oftentimes begins in adolescence, therefore understanding the pathophysiology in this period is important. Few studies investigated the possible impact of the acute state of illness on...

Showing 1 to 12 of 58 entries