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Showing 1 to 12 of 34 entries
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A Combination of Candesartan Cilexetil/hydrochlorothiazide (HCTZ), 8/12.5 mg, has a Similar Antihypertensive Efficacy and is Better Tolerated than Lisinopril/HCTZ, 10/12.5 mg.

Blood pressure

T McINNES G, Istad H, Keinänen-Kiukaanniemi S, VAN Mierlo HFCM.
PMID: 28425809
Blood Press. 2000;9:61. doi: 10.1080/080370500439344.

Monotherapy with an antihypertensive agent is likely to achieve a desirable lowering of blood pressure in about 50% of patients. The remaining proportion of patients are likely to be only partially responsive or unresponsive, even if appropriate dose adjustments...

Feasibility of Gamified Mobile Service Aimed at Physical Activation in Young Men: Population-Based Randomized Controlled Study (MOPO).

JMIR mHealth and uHealth

Leinonen AM, Pyky R, Ahola R, Kangas M, Siirtola P, Luoto T, Enwald H, Ikäheimo TM, Röning J, Keinänen-Kiukaanniemi S, Mäntysaari M, Korpelainen R, Jämsä T.
PMID: 29017991
JMIR Mhealth Uhealth. 2017 Oct 10;5(10):e146. doi: 10.2196/mhealth.6675.

BACKGROUND: The majority of young people do not meet the recommendations on physical activity for health. New innovative ways to motivate young people to adopt a physically active lifestyle are needed.OBJECTIVE: The study aimed to study the feasibility of...

Feasibility of videoconferencing in lifestyle group counselling.

International journal of circumpolar health

Laitinen J, Korkiakangas E, Alahuhta M, Keinänen-Kiukaanniemi S, Rajala U, Timonen O, Jokelainen T, Keränen AM, Remes J, Ruokonen A, Hedberg P, Taanila A, Husman P, Olkkonen S.
PMID: 21062570
Int J Circumpolar Health. 2010 Dec;69(5):500-11. doi: 10.3402/ijch.v69i5.17688. Epub 2010 Nov 08.

OBJECTIVES: The rapid increase in the prevalence of type 2 diabetes (T2D) has created an urgent need to develop new practices to prevent and treat it. One possibility is to provide specialists services to remote areas through videoconferencing (VC)....

Increase in physical activity and cardiometabolic risk profile change during lifestyle intervention in primary healthcare: 1-year follow-up study among individuals at high risk for type 2 diabetes.

BMJ open

Kujala UM, Jokelainen J, Oksa H, Saaristo T, Rautio N, Moilanen L, Korpi-Hyövälti E, Saltevo J, Vanhala M, Niskanen L, Peltonen M, Tuomilehto J, Uusitupa M, Keinänen-Kiukaannemi S.
PMID: 22184585
BMJ Open. 2011 Dec 19;1(2):e000292. doi: 10.1136/bmjopen-2011-000292. Print 2011.

Objectives To investigate the association between increase in physical activity and changes in cardiometabolic risk factors during a lifestyle intervention programme in routine clinical settings. Design Prospective follow-up. Setting 400 primary healthcare centres and occupational healthcare outpatient clinics in...

Association of Physical Activity With Telomere Length Among Elderly Adults - The Oulu Cohort 1945.

Frontiers in physiology

Stenbäck V, Mutt SJ, Leppäluoto J, Gagnon DD, Mäkelä KA, Jokelainen J, Keinänen-Kiukaanniemi S, Herzig KH.
PMID: 31105579
Front Physiol. 2019 Apr 24;10:444. doi: 10.3389/fphys.2019.00444. eCollection 2019.

No abstract available.

Cohort Profile: 46 years of follow-up of the Northern Finland Birth Cohort 1966 (NFBC1966).

International journal of epidemiology

Nordström T, Miettunen J, Auvinen J, Ala-Mursula L, Keinänen-Kiukaanniemi S, Veijola J, Järvelin MR, Sebert S, Männikkö M.
PMID: 34999878
Int J Epidemiol. 2022 Jan 06;50(6):1786-1787j. doi: 10.1093/ije/dyab109.

No abstract available.

Evaluation of High Cholesterol and Risk of Dementia and Cognitive Decline in Older Adults Using Individual Patient Meta-Analysis.

Dementia and geriatric cognitive disorders

Peters R, Xu Y, Antikainen R, Beckett N, Gussekloo J, Jagger C, Jukema JW, Keinanen-Kiukaanniemi S, Rydén L, Skoog I, Staessen JA, Thijs L, Trompet S, Tully PJ, Tzourio C, Anstey KJ.
PMID: 34700321
Dement Geriatr Cogn Disord. 2021;50(4):318-325. doi: 10.1159/000519452. Epub 2021 Oct 26.

INTRODUCTION: Although increased cholesterol level has been acknowledged as a risk factor for dementia, evidence synthesis based on published data has yielded mixed results. This is especially relevant in older adults where individual studies report non-linear relationships between cholesterol...

Cohort Profile: 46 years of follow-up of the Northern Finland Birth Cohort 1966 (NFBC1966).

International journal of epidemiology

Nordström T, Miettunen J, Auvinen J, Ala-Mursula L, Keinänen-Kiukaanniemi S, Veijola J, Järvelin MR, Sebert S, Männikkö M.
PMID: 34458907
Int J Epidemiol. 2021 Aug 29; doi: 10.1093/ije/dyab109. Epub 2021 Aug 29.

No abstract available.

Reliability of a simple method of measuring isometric neck muscle force.

Clinical biomechanics (Bristol, Avon)

Levoska S, Keinänen-Kiukanniemi S, Hämäläinen O, Jäms ̈ T, Vanharanta H.
PMID: 23915614
Clin Biomech (Bristol, Avon). 1992 Feb;7(1):33-7. doi: 10.1016/0268-0033(92)90005-O.

A new measurement device was constructed to measure the maximal isometric neck muscle forces. In this study the repeatability of the measurements was evaluated in 34 healthy reserve flying conscripts from Finnish Defence Forces. The measurements of the maximal...

Parental separation and offspring morbidity in adulthood: a descriptive study of the Northern Finland Birth Cohort 1966.

Scandinavian journal of public health

Varis H, Hagnäs M, Mikkola I, Nordström T, Puukka K, Taanila A, Keinänen-Kiukaanniemi S.
PMID: 34030537
Scand J Public Health. 2021 May 25;14034948211014296. doi: 10.1177/14034948211014296. Epub 2021 May 25.

No abstract available.

Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia.

Science advances

Auvinen J, Tapio J, Karhunen V, Kettunen J, Serpi R, Dimova EY, Gill D, Soininen P, Tammelin T, Mykkänen J, Puukka K, Kähönen M, Raitoharju E, Lehtimäki T, Ala-Korpela M, Raitakari OT, Keinänen-Kiukaanniemi S, Järvelin MR, Koivunen P.
PMID: 34261659
Sci Adv. 2021 Jul 14;7(29). doi: 10.1126/sciadv.abi4822. Print 2021 Jul.

Activation of the hypoxia-inducible factor (HIF) pathway reprograms energy metabolism. Hemoglobin (Hb) is the main carrier of oxygen. Using its normal variation as a surrogate measure for hypoxia, we explored whether lower Hb levels could lead to healthier metabolic...

Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis.

BMC medicine

Bouras E, Karhunen V, Gill D, Huang J, Haycock PC, Gunter MJ, Johansson M, Brennan P, Key T, Lewis SJ, Martin RM, Murphy N, Platz EA, Travis R, Yarmolinsky J, Zuber V, Martin P, Katsoulis M, Freisling H, Nøst TH, Schulze MB, Dossus L, Hung RJ, Amos CI, Ahola-Olli A, Palaniswamy S, Männikkö M, Auvinen J, Herzig KH, Keinänen-Kiukaanniemi S, Lehtimäki T, Salomaa V, Raitakari O, Salmi M, Jalkanen S, Jarvelin MR, Dehghan A, Tsilidis KK.
PMID: 35012533
BMC Med. 2022 Jan 11;20(1):3. doi: 10.1186/s12916-021-02193-0.

BACKGROUND: Epidemiological and experimental evidence has linked chronic inflammation to cancer aetiology. It is unclear whether associations for specific inflammatory biomarkers are causal or due to bias. In order to examine whether altered genetically predicted concentration of circulating cytokines...

Showing 1 to 12 of 34 entries