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Showing 1 to 12 of 15 entries
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Development of mesophasic microreservoir-based transdermal drug delivery system of propranolol.

Indian journal of pharmaceutical sciences

Omray LK, Kohli S, Khopade AJ, Patil S, Gajbhiye A, Agrawal GP.
PMID: 21394252
Indian J Pharm Sci. 2008 Sep;70(5):578-84. doi: 10.4103/0250-474X.45394.

The mesophasic microreservoir comprises lyotrophic liquid crystals. The liquid crystals were prepared of Brij-35, cetosteryl alcohol and propranolol and evaluated for parameters viz. anisotropy, size and size distribution and drug entrapment efficiency. Subsequent to this liquid crystals based transdermal...

An Adverse Effect of Higher Catalyst Loading and Longer Reaction Time on Enantioselectivity in an Organocatalytic Multicomponent Reaction.

Chemistry (Weinheim an der Bergstrasse, Germany)

Khopade TM, Mete TB, Arora JS, Bhat RG.
PMID: 29465758
Chemistry. 2018 Apr 20;24(23):6036-6040. doi: 10.1002/chem.201800278. Epub 2018 Mar 27.

An enantioselective organocatalytic multicomponent reaction of aldehydes, ketones, and Meldrum's acid has been developed. A cinchona-based primary amine (1 mol %) catalyses the multicomponent reaction via the formation of the Knoevenagel product and a chiral enamine to form enantiopure...

Multicomponent synthesis of pyroglutamic acid derivatives via Knoevenagel-Michael-hydrolysis-lactamization-decarboxylation (KMHL-D) sequence.

Organic & biomolecular chemistry

Khopade TM, Warghude PK, Sonawane AD, Bhat RG.
PMID: 30574984
Org Biomol Chem. 2019 Jan 16;17(3):561-566. doi: 10.1039/c8ob02473a.

A novel and practical method for the synthesis of 3-substituted pyroglutamic acid derivatives is described. One pot multicomponent reaction of Meldrum's acid, aldehyde and Schiff's base followed an unprecedented chemoselective Knoevenagel-Michael-hydrolysis-lactamization domino sequence to afford 4-carboxy 3-substituted pyroglutamic acid...

Determination of amino Acid content and protein quality of complementary food produced from locally available food materials in ondo state, Nigeria.

Malaysian journal of nutrition

Ijarotimi OS, Olopade AJ.
PMID: 22691808
Malays J Nutr. 2009 Mar;15(1):87-95. Epub 2009 Mar 15.

Protein-energy malnutrition is increasing among children in developing countries due to low nutrient density of traditional complementary diets. Therefore, this study aimed at determining the protein quality of a complementary food produced from cooking banana fruits and bambara groundnut...

Molecular Docking Studies of Phytocompounds from the Phyllanthus Species as Potential Chronic Pain Modulators.

Scientia pharmaceutica

Chopade AR, Sayyad FJ, Pore YV.
PMID: 26839814
Sci Pharm. 2014 Nov 08;83(2):243-67. doi: 10.3797/scipharm.1408-10. Print 2015.

The study of inflammatory pain has been one of the most rapidly advancing and expanding areas of pain research in recent years. Studies from our lab have demonstrated the chronic pain-modulating potential of the Phyllanthus species and their probable...

Identification of Anxiolytic Potential of Niranthin: In-vivo and Computational Investigations.

Natural products and bioprospecting

Chopade AR, Somade PM, Somade PP, Mali SN.
PMID: 33175328
Nat Prod Bioprospect. 2021 Apr;11(2):223-233. doi: 10.1007/s13659-020-00284-8. Epub 2020 Nov 11.

Anxiety is an unpleasant state, which can critically decrease the quality of life is often accompanied by nervous behaviour and rumination. Niranthin is a lignan isolated from various Phyllanthus sources. The literature survey on niranthin highlights wide ranges of...

Pharmacokinetics and Pharmacology of Latanoprost 0.005% without Benzalkonium Chloride Vs Latanoprost 0.005% with Benzalkonium Chloride in New Zealand White Rabbits and Beagles.

Current eye research

Halder A, Khopade AJ.
PMID: 33719796
Curr Eye Res. 2021 Jul;46(7):1031-1037. doi: 10.1080/02713683.2020.1855660. Epub 2021 Mar 15.

No abstract available.

Antioxidant, Antinociceptive and Anti-inflammatory Activities of Ethanolic Extract of Leaves of Alocasia indica (Schott.).

Journal of young pharmacists : JYP

Mulla W, Kuchekar S, Thorat V, Chopade A, Kuchekar B.
PMID: 21264115
J Young Pharm. 2010 Apr;2(2):137-43. doi: 10.4103/0975-1483.63152.

Extracts obtained from the leaves of various Alocasia species have been used in India as folk remedy for the treatment of various inflammatory ailments including rheumatism and bruise. The ethanolic extract of leaves of Alocasia indica Schott. was evaluated...

Single incision Laparoscopic repair of post CABG sternotomy sub xiphoid hernia.

Journal of minimal access surgery

Shah HK, Chaudhari N, Khopade S, Thombare B, Chavan SG.
PMID: 24250068
J Minim Access Surg. 2013 Oct;9(4):187-9. doi: 10.4103/0972-9941.118845.

The current decade has witnessed the evolution of Minimal Access Surgery (MAS) from Multi port Laparoscopy to Single Port Laparoscopy. The reduction of ports, subsequent scars and pain makes MAS more patients friendly. Symptomatic Subxiphoid Incisional hernias in patients...

Efficiency of Different Endodontic Irrigation and Activation Systems in Removal of the Smear Layer: A Scanning Electron Microscopy Study.

Iranian endodontic journal

Karade P, Chopade R, Patil S, Hoshing U, Rao M, Rane N, Chopade A, Kulkarni A.
PMID: 29225634
Iran Endod J. 2017;12(4):414-418. doi: 10.22037/iej.v12i4.9571.

INTRODUCTION: This METHODS AND MATERIALS: Forty recently extracted, non-carious human intact single rooted premolars were selected and divided into five groups (RESULTS: The four groups did not differ from each other in the coronal and mid-root parts of the...

Demonstrative fractional order - PID controller based DC motor drive on digital platform.

ISA transactions

Khubalkar SW, Junghare AS, Aware MV, Chopade AS, Das S.
PMID: 28941952
ISA Trans. 2018 Nov;82:79-93. doi: 10.1016/j.isatra.2017.08.019. Epub 2017 Sep 21.

In industrial drives applications, fractional order controllers can exhibit phenomenal impact due to realization through digital implementation. Digital fractional order controllers have created wide scope as it possess the inherent advantages like robustness against the plant parameter variation. This...

Bioinspired Brønsted Acid-Promoted Regioselective Tryptophan Isoprenylations.

ACS omega

Khopade TM, Ajayan K, Joshi SS, Lane AL, Viswanathan R.
PMID: 34056238
ACS Omega. 2021 Apr 12;6(16):10840-10858. doi: 10.1021/acsomega.1c00515. eCollection 2021 Apr 27.

Tryptophan-containing isoprenoid indole alkaloid natural products are well known for their intricate structural architectures and significant biological activities. Nature employs dimethylallyl tryptophan synthases (DMATSs) or aromatic indole prenyltransferases (iPTs) to catalyze regio- and stereoselective prenylation of l-Trp. Regioselective synthetic...

Showing 1 to 12 of 15 entries