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Showing 1 to 12 of 70 entries
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Tapering and discontinuation of methotrexate in patients with RA treated with TNF inhibitors: data from the DREAM registry.

RMD open

Manders SH, van de Laar MA, Rongen-van Dartel SA, Bos R, Visser H, Brus HL, Jansen T, Vonkeman HE, van Riel PL, Kievit W.
PMID: 26535151
RMD Open. 2015 Oct 08;1(1):e000147. doi: 10.1136/rmdopen-2015-000147. eCollection 2015.

OBJECTIVES: To study the number of patients that taper or discontinue concomitant methotrexate (MTX) in daily practice in patients with rheumatoid arthritis (RA) treated with tumour necrosis factor inhibitor (TNFi) and to analyse the effects of that adaption on...

Antithrombotic therapy in patients undergoing TAVI: an overview of Dutch hospitals.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Nijenhuis VJ, Stella PR, Baan J, Brueren BR, de Jaegere PP, den Heijer P, Hofma SH, Kievit P, Slagboom T, van den Heuvel AF, van der Kley F, van Garsse L, van Houwelingen KG, Van't Hof AW, Ten Berg JM.
PMID: 24287807
Neth Heart J. 2014 Feb;22(2):64-9. doi: 10.1007/s12471-013-0496-6.

PURPOSE: To assess current antithrombotic treatment strategies in the Netherlands in patients undergoing transcatheter aortic valve implantation (TAVI).METHODS: For every Dutch hospital performing TAVI (n = 14) an interventional cardiologist experienced in performing TAVI was interviewed concerning heparin, aspirin,...

Quality of life and costs for different treatment strategies for rheumatoid arthritis.

Expert review of pharmacoeconomics & outcomes research

Welsing PM, Kievit W, Laan R, Severens JL.
PMID: 19807258
Expert Rev Pharmacoecon Outcomes Res. 2005 Aug;5(4):395-410. doi: 10.1586/14737167.5.4.395.

Rheumatoid arthritis is a chronic, inflammatory, systemic disease. In the past, treatment (strategy) for this disease has changed dramatically, becoming more aggressive and new drugs have become available. Furthermore, closely monitoring the disease and treatment has been advocated. Rheumatoid...

Early High-Fat Diet Exposure Causes Dysregulation of the Orexin and Dopamine Neuronal Populations in Nonhuman Primates.

Frontiers in endocrinology

True C, Arik A, Lindsley S, Kirigiti M, Sullivan E, Kievit P.
PMID: 30258403
Front Endocrinol (Lausanne). 2018 Sep 10;9:508. doi: 10.3389/fendo.2018.00508. eCollection 2018.

Maternal obesity and consumption of a high-fat diet (HFD) during pregnancy has a negative impact on offspring, including an increased risk for the development of obesity in adolescence. The mechanism for this transferred metabolic risk is unclear, but many...

Healthcare providers perception of therapeutic patient education efficacy according to patient and healthcare provider characteristics.

Chronic illness

Loyal D, Ricci L, Villegente J, Ayav C, Kivits J, Rat AC.
PMID: 34894789
Chronic Illn. 2021 Dec 13;17423953211058411. doi: 10.1177/17423953211058411. Epub 2021 Dec 13.

OBJECTIVES: Therapeutic patient education improves numerous health and psychological outcomes in patients with chronic diseases. However, little is known about what makes a therapeutic patient education intervention more effective than another one. This study aims to identify in healthcare...

If You Want to Perform a Cost-effectiveness Trial, First Do a Modeling Study.

The Journal of rheumatology

Kievit W, den Broeder AA.
PMID: 33649068
J Rheumatol. 2021 Apr;48(4):473-475. doi: 10.3899/jrheum.201430. Epub 2021 Mar 01.

No abstract available.

Fibroblast Growth Factor-1 Activates Neurons in the Arcuate Nucleus and Dorsal Vagal Complex.

Frontiers in endocrinology

Roberts BL, Kim EJ, Lindsley SR, Tennant KG, Kievit P.
PMID: 34987476
Front Endocrinol (Lausanne). 2021 Dec 20;12:772909. doi: 10.3389/fendo.2021.772909. eCollection 2021.

Central administration of fibroblast growth factor-1 (FGF1) results in long-lasting resolution of hyperglycemia in various rodent models, but the pre- and postsynaptic mechanisms mediating the central effects of FGF1 are unknown. Here we utilize electrophysiology recordings from neuronal populations...

Tailored patient therapeutic educational interventions: A patient-centred communication model.

Health expectations : an international journal of public participation in health care and health policy

Ricci L, Villegente J, Loyal D, Ayav C, Kivits J, Rat AC.
PMID: 34816546
Health Expect. 2021 Nov 24; doi: 10.1111/hex.13377. Epub 2021 Nov 24.

BACKGROUND: Tailoring therapeutic education consists of adapting the intervention to patients' needs with the expectation that this individualization will improve the results of the intervention. Communication is the basis for any individualization process. To our knowledge, there is no...

Dimensions of the Complexity of Health Interventions: What Are We Talking About? A Review.

International journal of environmental research and public health

Trompette J, Kivits J, Minary L, Alla F.
PMID: 32354085
Int J Environ Res Public Health. 2020 Apr 28;17(9). doi: 10.3390/ijerph17093069.

Many recommendations and innovative approaches are available for the development and evaluation of complex health interventions. We investigated the dimensions of complexity described in health research and how these descriptions may affect the adopted research methodology (e.g., the choice...

Palmitic Acid Targets Human Testicular Peritubular Cells and Causes a Pro-Inflammatory Response.

Journal of clinical medicine

Mayerhofer A, Dietrich KG, Urbanski HF, Köhn FM, Pickl U, Trottmann M, Kievit P, Welter H.
PMID: 32824411
J Clin Med. 2020 Aug 17;9(8). doi: 10.3390/jcm9082655.

Palmitic acid (PA) is a major fatty acid, derived from diet and endogenous production, which is being linked to inflammation. While such actions of PA at the level of the testis remain difficult to examine, we reasoned that studies...

[New drugs available more quickly for the right patient].

Nederlands tijdschrift voor geneeskunde

Kievit W, Berden FA, Drenth JP.
PMID: 27734779
Ned Tijdschr Geneeskd. 2016;160:D735.

Pharmaceutical companies are under increasing scrutiny because of their strategy for gaining market access and reimbursement authorisation for novel drugs. The tool most often used is that of a randomised controlled trial (RCT) in a highly selected population that...

Short-term Western-style diet negatively impacts reproductive outcomes in primates.

JCI insight

Ravisankar S, Ting AY, Murphy MJ, Redmayne N, Wang D, McArthur CA, Takahashi DL, Kievit P, Chavez SL, Hennebold JD.
PMID: 33616080
JCI Insight. 2021 Feb 22;6(4). doi: 10.1172/jci.insight.138312.

A maternal Western-style diet (WSD) is associated with poor reproductive outcomes, but whether this is from the diet itself or underlying metabolic dysfunction is unknown. Here, we performed a longitudinal study using regularly cycling female rhesus macaques (n =...

Showing 1 to 12 of 70 entries