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Identification of MS-specific serum miRNAs in an international multicenter study.

Neurology(R) neuroimmunology & neuroinflammation

Regev K, Healy BC, Paul A, Diaz-Cruz C, Mazzola MA, Raheja R, Glanz BI, Kivisäkk P, Chitnis T, Jagodic M, Piehl F, Olsson T, Khademi M, Hauser S, Oksenberg J, Khoury SJ, Weiner HL, Gandhi R.
PMID: 30175165
Neurol Neuroimmunol Neuroinflamm. 2018 Aug 20;5(5):e491. doi: 10.1212/NXI.0000000000000491. eCollection 2018 Sep.

OBJECTIVE: To identify circulating microRNAs (miRNAs) linked to disease, disease stage, and disability in MS across cohorts.METHODS: Samples were obtained from the Comprehensive Longitudinal Investigation of Multiple Sclerosis (CLIMB, Boston, MA), EPIC (San Francisco, CA), AMIR (Beirut, Lebanon) as...

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Regev K, Healy BC, Paul A, et al. Identification of MS-specific serum miRNAs in an international multicenter study. Neurol Neuroimmunol Neuroinflamm. 2018;5(5):e491doi: 10.1212/NXI.0000000000000491.
Regev, K., Healy, B. C., Paul, A., Diaz-Cruz, C., Mazzola, M. A., Raheja, R., Glanz, B. I., Kivisäkk, P., Chitnis, T., Jagodic, M., Piehl, F., Olsson, T., Khademi, M., Hauser, S., Oksenberg, J., Khoury, S. J., Weiner, H. L., & Gandhi, R. (2018). Identification of MS-specific serum miRNAs in an international multicenter study. Neurology(R) neuroimmunology & neuroinflammation, 5(5), e491. https://doi.org/10.1212/NXI.0000000000000491
Regev, Keren, et al. "Identification of MS-specific serum miRNAs in an international multicenter study." Neurology(R) neuroimmunology & neuroinflammation vol. 5,5 (2018): e491. doi: https://doi.org/10.1212/NXI.0000000000000491
Regev K, Healy BC, Paul A, Diaz-Cruz C, Mazzola MA, Raheja R, Glanz BI, Kivisäkk P, Chitnis T, Jagodic M, Piehl F, Olsson T, Khademi M, Hauser S, Oksenberg J, Khoury SJ, Weiner HL, Gandhi R. Identification of MS-specific serum miRNAs in an international multicenter study. Neurol Neuroimmunol Neuroinflamm. 2018 Aug 20;5(5):e491. doi: 10.1212/NXI.0000000000000491. eCollection 2018 Sep. PMID: 30175165; PMCID: PMC6117192.
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Social support may prevent self-cutting in adolescence: A 5-year follow-up study.

Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc

Rissanen ML, Kekkonen V, Kraav SL, Kivimäki P, Laukkanen E, Hintikka J, Tolmunen T.
PMID: 34164876
J Child Adolesc Psychiatr Nurs. 2021 Nov;34(4):343-351. doi: 10.1111/jcap.12341. Epub 2021 Jun 24.

Self-cutting is common among adolescents. However, studies examining protective factors are rare. It has been suggested that social support may protect against self-cutting in adolescence. The aim of this study was to investigate the possible association of social relationships...

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Rissanen ML, Kekkonen V, Kraav SL, et al. Social support may prevent self-cutting in adolescence: A 5-year follow-up study. J Child Adolesc Psychiatr Nurs. 2021;34(4):343-351doi: 10.1111/jcap.12341.
Rissanen, M. L., Kekkonen, V., Kraav, S. L., Kivimäki, P., Laukkanen, E., Hintikka, J., & Tolmunen, T. (2021). Social support may prevent self-cutting in adolescence: A 5-year follow-up study. Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc, 34(4), 343-351. https://doi.org/10.1111/jcap.12341
Rissanen, Marja-Liisa, et al. "Social support may prevent self-cutting in adolescence: A 5-year follow-up study." Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc vol. 34,4 (2021): 343-351. doi: https://doi.org/10.1111/jcap.12341
Rissanen ML, Kekkonen V, Kraav SL, Kivimäki P, Laukkanen E, Hintikka J, Tolmunen T. Social support may prevent self-cutting in adolescence: A 5-year follow-up study. J Child Adolesc Psychiatr Nurs. 2021 Nov;34(4):343-351. doi: 10.1111/jcap.12341. Epub 2021 Jun 24. PMID: 34164876.
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Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome.

Nature communications

Roostaei T, Klein HU, Ma Y, Felsky D, Kivisäkk P, Connor SM, Kroshilina A, Yung C, Kaskow BJ, Shao X, Rhead B, Ordovás JM, Absher DM, Arnett DK, Liu J, Patsopoulos N, Barcellos LF, Weiner HL, De Jager PL.
PMID: 34873174
Nat Commun. 2021 Dec 06;12(1):7078. doi: 10.1038/s41467-021-27427-w.

Identifying the effects of genetic variation on the epigenome in disease-relevant cell types can help advance our understanding of the first molecular contributions of genetic susceptibility to disease onset. Here, we establish a genome-wide map of DNA methylation quantitative...

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Roostaei T, Klein HU, Ma Y, et al. Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome. Nat Commun. 2021;12(1):7078doi: 10.1038/s41467-021-27427-w.
Roostaei, T., Klein, H. U., Ma, Y., Felsky, D., Kivisäkk, P., Connor, S. M., Kroshilina, A., Yung, C., Kaskow, B. J., Shao, X., Rhead, B., Ordovás, J. M., Absher, D. M., Arnett, D. K., Liu, J., Patsopoulos, N., Barcellos, L. F., Weiner, H. L., & De Jager, P. L. (2021). Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome. Nature communications, 12(1), 7078. https://doi.org/10.1038/s41467-021-27427-w
Roostaei, Tina, et al. "Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome." Nature communications vol. 12,1 (2021): 7078. doi: https://doi.org/10.1038/s41467-021-27427-w
Roostaei T, Klein HU, Ma Y, Felsky D, Kivisäkk P, Connor SM, Kroshilina A, Yung C, Kaskow BJ, Shao X, Rhead B, Ordovás JM, Absher DM, Arnett DK, Liu J, Patsopoulos N, Barcellos LF, Weiner HL, De Jager PL. Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome. Nat Commun. 2021 Dec 06;12(1):7078. doi: 10.1038/s41467-021-27427-w. PMID: 34873174.
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Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis.

Neurology(R) neuroimmunology & neuroinflammation

Regev K, Paul A, Healy B, von Glenn F, Diaz-Cruz C, Gholipour T, Mazzola MA, Raheja R, Nejad P, Glanz BI, Kivisakk P, Chitnis T, Weiner HL, Gandhi R.
PMID: 27606352
Neurol Neuroimmunol Neuroinflamm. 2016 Aug 23;3(5):e267. doi: 10.1212/NXI.0000000000000267. eCollection 2016 Oct.

OBJECTIVE: To identify circulating microRNAs (miRNAs) linked to disease stage and disability in multiple sclerosis (MS).METHODS: Sera from 296 participants including patients with MS, other neurologic diseases (Alzheimer disease and amyotrophic lateral sclerosis), and inflammatory diseases (rheumatoid arthritis and...

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Regev K, Paul A, Healy B, et al. Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2016;3(5):e267doi: 10.1212/NXI.0000000000000267.
Regev, K., Paul, A., Healy, B., von Glenn, F., Diaz-Cruz, C., Gholipour, T., Mazzola, M. A., Raheja, R., Nejad, P., Glanz, B. I., Kivisakk, P., Chitnis, T., Weiner, H. L., & Gandhi, R. (2016). Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis. Neurology(R) neuroimmunology & neuroinflammation, 3(5), e267. https://doi.org/10.1212/NXI.0000000000000267
Regev, Keren, et al. "Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis." Neurology(R) neuroimmunology & neuroinflammation vol. 3,5 (2016): e267. doi: https://doi.org/10.1212/NXI.0000000000000267
Regev K, Paul A, Healy B, von Glenn F, Diaz-Cruz C, Gholipour T, Mazzola MA, Raheja R, Nejad P, Glanz BI, Kivisakk P, Chitnis T, Weiner HL, Gandhi R. Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2016 Aug 23;3(5):e267. doi: 10.1212/NXI.0000000000000267. eCollection 2016 Oct. PMID: 27606352; PMCID: PMC4996540.
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Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS.

Neurology(R) neuroimmunology & neuroinflammation

Rothhammer V, Borucki DM, Garcia Sanchez MI, Mazzola MA, Hemond CC, Regev K, Paul A, Kivisäkk P, Bakshi R, Izquierdo G, Weiner HL, Quintana FJ.
PMID: 28642887
Neurol Neuroimmunol Neuroinflamm. 2017 Jun 16;4(4):e359. doi: 10.1212/NXI.0000000000000359. eCollection 2017 Jul.

OBJECTIVE: Several factors influence the clinical course of autoimmune inflammatory diseases such as MS and inflammatory bowel disease. Only recently, the complex interaction between the gut microbiome, dietary factors, and metabolism has started to be appreciated with regard to...

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Rothhammer V, Borucki DM, Garcia Sanchez MI, et al. Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS. Neurol Neuroimmunol Neuroinflamm. 2017;4(4):e359doi: 10.1212/NXI.0000000000000359.
Rothhammer, V., Borucki, D. M., Garcia Sanchez, M. I., Mazzola, M. A., Hemond, C. C., Regev, K., Paul, A., Kivisäkk, P., Bakshi, R., Izquierdo, G., Weiner, H. L., & Quintana, F. J. (2017). Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS. Neurology(R) neuroimmunology & neuroinflammation, 4(4), e359. https://doi.org/10.1212/NXI.0000000000000359
Rothhammer, Veit, et al. "Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS." Neurology(R) neuroimmunology & neuroinflammation vol. 4,4 (2017): e359. doi: https://doi.org/10.1212/NXI.0000000000000359
Rothhammer V, Borucki DM, Garcia Sanchez MI, Mazzola MA, Hemond CC, Regev K, Paul A, Kivisäkk P, Bakshi R, Izquierdo G, Weiner HL, Quintana FJ. Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS. Neurol Neuroimmunol Neuroinflamm. 2017 Jun 16;4(4):e359. doi: 10.1212/NXI.0000000000000359. eCollection 2017 Jul. PMID: 28642887; PMCID: PMC5473958.
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Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis.

Neurology(R) neuroimmunology & neuroinflammation

Bakshi R, Yeste A, Patel B, Tauhid S, Tummala S, Rahbari R, Chu R, Regev K, Kivisäkk P, Weiner HL, Quintana FJ.
PMID: 26894204
Neurol Neuroimmunol Neuroinflamm. 2016 Jan 27;3(2):e200. doi: 10.1212/NXI.0000000000000200. eCollection 2016 Apr.

OBJECTIVE: To determine whether peripheral immune responses as measured by serum antigen arrays are linked to cerebral MRI measures of disease severity in multiple sclerosis (MS).METHODS: In this cross-sectional study, serum samples were obtained from patients with relapsing-remitting MS...

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Bakshi R, Yeste A, Patel B, et al. Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2016;3(2):e200doi: 10.1212/NXI.0000000000000200.
Bakshi, R., Yeste, A., Patel, B., Tauhid, S., Tummala, S., Rahbari, R., Chu, R., Regev, K., Kivisäkk, P., Weiner, H. L., & Quintana, F. J. (2016). Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis. Neurology(R) neuroimmunology & neuroinflammation, 3(2), e200. https://doi.org/10.1212/NXI.0000000000000200
Bakshi, Rohit, et al. "Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis." Neurology(R) neuroimmunology & neuroinflammation vol. 3,2 (2016): e200. doi: https://doi.org/10.1212/NXI.0000000000000200
Bakshi R, Yeste A, Patel B, Tauhid S, Tummala S, Rahbari R, Chu R, Regev K, Kivisäkk P, Weiner HL, Quintana FJ. Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2016 Jan 27;3(2):e200. doi: 10.1212/NXI.0000000000000200. eCollection 2016 Apr. PMID: 26894204; PMCID: PMC4747479.
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Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome.

Nature communications

Roostaei T, Klein HU, Ma Y, Felsky D, Kivisäkk P, Connor SM, Kroshilina A, Yung C, Kaskow BJ, Shao X, Rhead B, Ordovás JM, Absher DM, Arnett DK, Liu J, Patsopoulos N, Barcellos LF, Weiner HL, De Jager PL.
PMID: 34873174
Nat Commun. 2021 Dec 06;12(1):7078. doi: 10.1038/s41467-021-27427-w.

Identifying the effects of genetic variation on the epigenome in disease-relevant cell types can help advance our understanding of the first molecular contributions of genetic susceptibility to disease onset. Here, we establish a genome-wide map of DNA methylation quantitative...

Cite
Roostaei T, Klein HU, Ma Y, et al. Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome. Nat Commun. 2021;12(1):7078doi: 10.1038/s41467-021-27427-w.
Roostaei, T., Klein, H. U., Ma, Y., Felsky, D., Kivisäkk, P., Connor, S. M., Kroshilina, A., Yung, C., Kaskow, B. J., Shao, X., Rhead, B., Ordovás, J. M., Absher, D. M., Arnett, D. K., Liu, J., Patsopoulos, N., Barcellos, L. F., Weiner, H. L., & De Jager, P. L. (2021). Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome. Nature communications, 12(1), 7078. https://doi.org/10.1038/s41467-021-27427-w
Roostaei, Tina, et al. "Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome." Nature communications vol. 12,1 (2021): 7078. doi: https://doi.org/10.1038/s41467-021-27427-w
Roostaei T, Klein HU, Ma Y, Felsky D, Kivisäkk P, Connor SM, Kroshilina A, Yung C, Kaskow BJ, Shao X, Rhead B, Ordovás JM, Absher DM, Arnett DK, Liu J, Patsopoulos N, Barcellos LF, Weiner HL, De Jager PL. Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome. Nat Commun. 2021 Dec 06;12(1):7078. doi: 10.1038/s41467-021-27427-w. PMID: 34873174; PMCID: PMC8648735.
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Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study.

Journal of neuroinflammation

Vasunilashorn SM, Ngo LH, Dillon ST, Fong TG, Carlyle BC, Kivisäkk P, Trombetta BA, Vlassakov KV, Kunze LJ, Arnold SE, Xie Z, Inouye SK, Libermann TA, Marcantonio ER.
PMID: 33931093
J Neuroinflammation. 2021 Apr 30;18(1):103. doi: 10.1186/s12974-021-02145-8.

BACKGROUND: Our understanding of the relationship between plasma and cerebrospinal fluid (CSF) remains limited, which poses an obstacle to the identification of blood-based markers of neuroinflammatory disorders. To better understand the relationship between peripheral and central nervous system (CNS)...

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Vasunilashorn SM, Ngo LH, Dillon ST, et al. Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study. J Neuroinflammation. 2021;18(1):103doi: 10.1186/s12974-021-02145-8.
Vasunilashorn, S. M., Ngo, L. H., Dillon, S. T., Fong, T. G., Carlyle, B. C., Kivisäkk, P., Trombetta, B. A., Vlassakov, K. V., Kunze, L. J., Arnold, S. E., Xie, Z., Inouye, S. K., Libermann, T. A., Marcantonio, E. R. (2021). Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study. Journal of neuroinflammation, 18(1), 103. https://doi.org/10.1186/s12974-021-02145-8
Vasunilashorn, Sarinnapha M, et al. "Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study." Journal of neuroinflammation vol. 18,1 (2021): 103. doi: https://doi.org/10.1186/s12974-021-02145-8
Vasunilashorn SM, Ngo LH, Dillon ST, Fong TG, Carlyle BC, Kivisäkk P, Trombetta BA, Vlassakov KV, Kunze LJ, Arnold SE, Xie Z, Inouye SK, Libermann TA, Marcantonio ER. Plasma and cerebrospinal fluid inflammation and the blood-brain barrier in older surgical patients: the Role of Inflammation after Surgery for Elders (RISE) study. J Neuroinflammation. 2021 Apr 30;18(1):103. doi: 10.1186/s12974-021-02145-8. PMID: 33931093; PMCID: PMC8088047.
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Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults.

Alzheimer's & dementia (New York, N. Y.)

Fong TG, Vasunilashorn SM, Gou Y, Libermann TA, Dillon S, Schmitt E, Arnold SE, Kivisäkk P, Carlyle B, Oh ES, Vlassakov K, Kunze L, Hshieh T, Jones RN, Marcantonio ER, Inouye SK.
PMID: 33748398
Alzheimers Dement (N Y). 2021 Mar 17;7(1):e12125. doi: 10.1002/trc2.12125. eCollection 2021.

INTRODUCTION: The interaction between delirium and dementia is complex. We examined if Alzheimer's disease (AD) biomarkers in patients without clinical dementia are associated with increased risk of postoperative delirium, and whether AD biomarkers demonstrate a graded association with delirium...

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Fong TG, Vasunilashorn SM, Gou Y, et al. Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults. Alzheimers Dement (N Y). 2021;7(1):e12125doi: 10.1002/trc2.12125.
Fong, T. G., Vasunilashorn, S. M., Gou, Y., Libermann, T. A., Dillon, S., Schmitt, E., Arnold, S. E., Kivisäkk, P., Carlyle, B., Oh, E. S., Vlassakov, K., Kunze, L., Hshieh, T., Jones, R. N., Marcantonio, E. R., Inouye, S. K. (2021). Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults. Alzheimer's & dementia (New York, N. Y.), 7(1), e12125. https://doi.org/10.1002/trc2.12125
Fong, Tamara G, et al. "Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults." Alzheimer's & dementia (New York, N. Y.) vol. 7,1 (2021): e12125. doi: https://doi.org/10.1002/trc2.12125
Fong TG, Vasunilashorn SM, Gou Y, Libermann TA, Dillon S, Schmitt E, Arnold SE, Kivisäkk P, Carlyle B, Oh ES, Vlassakov K, Kunze L, Hshieh T, Jones RN, Marcantonio ER, Inouye SK. Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults. Alzheimers Dement (N Y). 2021 Mar 17;7(1):e12125. doi: 10.1002/trc2.12125. eCollection 2021. PMID: 33748398; PMCID: PMC7968120.
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Effect of vitamin D on MS activity by disease-modifying therapy class.

Neurology(R) neuroimmunology & neuroinflammation

Rotstein DL, Healy BC, Malik MT, Carruthers RL, Musallam AJ, Kivisakk P, Weiner HL, Glanz B, Chitnis T.
PMID: 26568968
Neurol Neuroimmunol Neuroinflamm. 2015 Oct 29;2(6):e167. doi: 10.1212/NXI.0000000000000167. eCollection 2015 Dec.

OBJECTIVE: To determine whether vitamin D status predicts disease activity in patients with multiple sclerosis (MS) taking interferon-β (IFN), glatiramer acetate (GA), and fingolimod (FTY).METHODS: Participants (n = 324) with relapsing-remitting MS on IFN (96), GA (151), or FTY...

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Rotstein DL, Healy BC, Malik MT, et al. Effect of vitamin D on MS activity by disease-modifying therapy class. Neurol Neuroimmunol Neuroinflamm. 2015;2(6):e167doi: 10.1212/NXI.0000000000000167.
Rotstein, D. L., Healy, B. C., Malik, M. T., Carruthers, R. L., Musallam, A. J., Kivisakk, P., Weiner, H. L., Glanz, B., & Chitnis, T. (2015). Effect of vitamin D on MS activity by disease-modifying therapy class. Neurology(R) neuroimmunology & neuroinflammation, 2(6), e167. https://doi.org/10.1212/NXI.0000000000000167
Rotstein, Dalia L, et al. "Effect of vitamin D on MS activity by disease-modifying therapy class." Neurology(R) neuroimmunology & neuroinflammation vol. 2,6 (2015): e167. doi: https://doi.org/10.1212/NXI.0000000000000167
Rotstein DL, Healy BC, Malik MT, Carruthers RL, Musallam AJ, Kivisakk P, Weiner HL, Glanz B, Chitnis T. Effect of vitamin D on MS activity by disease-modifying therapy class. Neurol Neuroimmunol Neuroinflamm. 2015 Oct 29;2(6):e167. doi: 10.1212/NXI.0000000000000167. eCollection 2015 Dec. PMID: 26568968; PMCID: PMC4630683.
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Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis.

Annals of clinical and translational neurology

Chitnis T, Gonzalez C, Healy BC, Saxena S, Rosso M, Barro C, Michalak Z, Paul A, Kivisakk P, Diaz-Cruz C, Sattarnezhad N, Pierre IV, Glanz BI, Tomic D, Kropshofer H, Häring D, Leppert D, Kappos L, Bakshi R, Weiner HL, Kuhle J.
PMID: 30564615
Ann Clin Transl Neurol. 2018 Oct 16;5(12):1478-1491. doi: 10.1002/acn3.638. eCollection 2018 Dec.

OBJECTIVE: To assess the value of annual serum neurofilament light (NfL) measures in predicting 10-year clinical and MRI outcomes in multiple sclerosis (MS).METHODS: We identified patients in our center's Comprehensive Longitudinal Investigations in MS at Brigham and Women's Hospital...

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Chitnis T, Gonzalez C, Healy BC, et al. Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis. Ann Clin Transl Neurol. 2018;5(12):1478-1491doi: 10.1002/acn3.638.
Chitnis, T., Gonzalez, C., Healy, B. C., Saxena, S., Rosso, M., Barro, C., Michalak, Z., Paul, A., Kivisakk, P., Diaz-Cruz, C., Sattarnezhad, N., Pierre, I. V., Glanz, B. I., Tomic, D., Kropshofer, H., Häring, D., Leppert, D., Kappos, L., Bakshi, R., Weiner, H. L., & Kuhle, J. (2018). Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis. Annals of clinical and translational neurology, 5(12), 1478-1491. https://doi.org/10.1002/acn3.638
Chitnis, Tanuja, et al. "Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis." Annals of clinical and translational neurology vol. 5,12 (2018): 1478-1491. doi: https://doi.org/10.1002/acn3.638
Chitnis T, Gonzalez C, Healy BC, Saxena S, Rosso M, Barro C, Michalak Z, Paul A, Kivisakk P, Diaz-Cruz C, Sattarnezhad N, Pierre IV, Glanz BI, Tomic D, Kropshofer H, Häring D, Leppert D, Kappos L, Bakshi R, Weiner HL, Kuhle J. Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis. Ann Clin Transl Neurol. 2018 Oct 16;5(12):1478-1491. doi: 10.1002/acn3.638. eCollection 2018 Dec. PMID: 30564615; PMCID: PMC6292183.
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Influence of IFN-beta1b (Betaferon) on cytokine mRNA profiles in blood mononuclear cells and plasma levels of soluble VCAM-1 in multiple sclerosis.

European journal of neurology

Fredrikson S, Kivisakk P, Link H, Matusevicius D, Navikas V, Soderstrom M, Tian W.
PMID: 10210841
Eur J Neurol. 1998 May;5(3):265-275. doi: 10.1046/j.1468-1331.1998.530265.x.

Inflammatory cell infiltration within the central nervous system (CNS) and upregulation of both pro- and anti-inflammatory cytokines are characteristic for multiple sclerosis (MS). Treatment with interferon-beta 1b (IFN-beta1b) reduces the number and severity of MS relapses. To examine whether...

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Fredrikson S, Kivisakk P, Link H, et al. Influence of IFN-beta1b (Betaferon) on cytokine mRNA profiles in blood mononuclear cells and plasma levels of soluble VCAM-1 in multiple sclerosis. Eur J Neurol. 1998;5(3):265-275doi: 10.1046/j.1468-1331.1998.530265.x.
Fredrikson, S., Kivisakk, P., Link, H., Matusevicius, D., Navikas, V., Soderstrom, M., & Tian, W. (1998). Influence of IFN-beta1b (Betaferon) on cytokine mRNA profiles in blood mononuclear cells and plasma levels of soluble VCAM-1 in multiple sclerosis. European journal of neurology, 5(3), 265-275. https://doi.org/10.1046/j.1468-1331.1998.530265.x
Fredrikson, et al. "Influence of IFN-beta1b (Betaferon) on cytokine mRNA profiles in blood mononuclear cells and plasma levels of soluble VCAM-1 in multiple sclerosis." European journal of neurology vol. 5,3 (1998): 265-275. doi: https://doi.org/10.1046/j.1468-1331.1998.530265.x
Fredrikson S, Kivisakk P, Link H, Matusevicius D, Navikas V, Soderstrom M, Tian W. Influence of IFN-beta1b (Betaferon) on cytokine mRNA profiles in blood mononuclear cells and plasma levels of soluble VCAM-1 in multiple sclerosis. Eur J Neurol. 1998 May;5(3):265-275. doi: 10.1046/j.1468-1331.1998.530265.x. PMID: 10210841.
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Showing 1 to 12 of 15 entries