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Shell.

Journal of palliative medicine

Plunk W.
PMID: 28375817
J Palliat Med. 2017 Aug;20(8):900. doi: 10.1089/jpm.2017.0078. Epub 2017 Apr 04.

No abstract available.

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Plunk W. Shell. J Palliat Med. 2017;20(8):900doi: 10.1089/jpm.2017.0078.
Plunk, W. (2017). Shell. Journal of palliative medicine, 20(8), 900. https://doi.org/10.1089/jpm.2017.0078
Plunk, William. "Shell." Journal of palliative medicine vol. 20,8 (2017): 900. doi: https://doi.org/10.1089/jpm.2017.0078
Plunk W. Shell. J Palliat Med. 2017 Aug;20(8):900. doi: 10.1089/jpm.2017.0078. Epub 2017 Apr 04. PMID: 28375817.
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Commentary on "Diagnosis of Alzheimer's disease: two decades of progress." Diagnosis of Alzheimer's disease: walking a well-paved path.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Klunk WE.
PMID: 19595833
Alzheimers Dement. 2005 Oct;1(2):99-100. doi: 10.1016/j.jalz.2005.10.002.

No abstract available.

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Klunk WE. Commentary on "Diagnosis of Alzheimer's disease: two decades of progress." Diagnosis of Alzheimer's disease: walking a well-paved path. Alzheimers Dement. 2005;1(2):99-100doi: 10.1016/j.jalz.2005.10.002.
Klunk, W. E. (2005). Commentary on "Diagnosis of Alzheimer's disease: two decades of progress." Diagnosis of Alzheimer's disease: walking a well-paved path. Alzheimer's & dementia : the journal of the Alzheimer's Association, 1(2), 99-100. https://doi.org/10.1016/j.jalz.2005.10.002
Klunk, William E. "Commentary on "Diagnosis of Alzheimer's disease: two decades of progress." Diagnosis of Alzheimer's disease: walking a well-paved path." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. 1,2 (2005): 99-100. doi: https://doi.org/10.1016/j.jalz.2005.10.002
Klunk WE. Commentary on "Diagnosis of Alzheimer's disease: two decades of progress." Diagnosis of Alzheimer's disease: walking a well-paved path. Alzheimers Dement. 2005 Oct;1(2):99-100. doi: 10.1016/j.jalz.2005.10.002. PMID: 19595833.
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Anti-Amyloid Effects of Small Molecule AÎČ-Binding Agents in PS1/APP Mice.

Letters in drug design & discovery

Cohen AD, Ikonomovic MD, Abrahamson EE, Paljug WR, Dekosky ST, Lefterov IM, Koldamova RP, Shao L, Debnath ML, Mason NS, Mathis CA, Klunk WE.
PMID: 20119496
Lett Drug Des Discov. 2009 Sep;6(6):437. doi: 10.2174/157018009789057526.

AIMS: One promising approach for treatment of Alzheimer's disease (AD) is use of anti-amyloid therapies, based on the hypothesis that increases in amyloid-beta (AÎČ) deposits in brain are a major cause of AD. Several groups have focused on AÎČ...

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Cohen AD, Ikonomovic MD, Abrahamson EE, et al. Anti-Amyloid Effects of Small Molecule AÎČ-Binding Agents in PS1/APP Mice. Lett Drug Des Discov. 2009;6(6):437doi: 10.2174/157018009789057526.
Cohen, A. D., Ikonomovic, M. D., Abrahamson, E. E., Paljug, W. R., Dekosky, S. T., Lefterov, I. M., Koldamova, R. P., Shao, L., Debnath, M. L., Mason, N. S., Mathis, C. A., & Klunk, W. E. (2009). Anti-Amyloid Effects of Small Molecule AÎČ-Binding Agents in PS1/APP Mice. Letters in drug design & discovery, 6(6), 437. https://doi.org/10.2174/157018009789057526
Cohen, A D, et al. "Anti-Amyloid Effects of Small Molecule AÎČ-Binding Agents in PS1/APP Mice." Letters in drug design & discovery vol. 6,6 (2009): 437. doi: https://doi.org/10.2174/157018009789057526
Cohen AD, Ikonomovic MD, Abrahamson EE, Paljug WR, Dekosky ST, Lefterov IM, Koldamova RP, Shao L, Debnath ML, Mason NS, Mathis CA, Klunk WE. Anti-Amyloid Effects of Small Molecule AÎČ-Binding Agents in PS1/APP Mice. Lett Drug Des Discov. 2009 Sep;6(6):437. doi: 10.2174/157018009789057526. PMID: 20119496; PMCID: PMC2812908.
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Correction: The paradox of HBV evolution as revealed from a 16th century mummy.

PLoS pathogens

Patterson Ross Z, Klunk J, Fornaciari G, Giuffra V, DuchĂȘne S, Duggan AT, Poinar D, Douglas MW, Eden JS, Holmes EC, Poinar HN.
PMID: 29425240
PLoS Pathog. 2018 Feb 09;14(2):e1006887. doi: 10.1371/journal.ppat.1006887. eCollection 2018 Feb.

[This corrects the article DOI: 10.1371/journal.ppat.1006750.].

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Patterson Ross Z, Klunk J, Fornaciari G, et al. Correction: The paradox of HBV evolution as revealed from a 16th century mummy. PLoS Pathog. 2018;14(2):e1006887doi: 10.1371/journal.ppat.1006887.
Patterson Ross, Z., Klunk, J., Fornaciari, G., Giuffra, V., DuchĂȘne, S., Duggan, A. T., Poinar, D., Douglas, M. W., Eden, J. S., Holmes, E. C., & Poinar, H. N. (2018). Correction: The paradox of HBV evolution as revealed from a 16th century mummy. PLoS pathogens, 14(2), e1006887. https://doi.org/10.1371/journal.ppat.1006887
Patterson Ross, Zoe, et al. "Correction: The paradox of HBV evolution as revealed from a 16th century mummy." PLoS pathogens vol. 14,2 (2018): e1006887. doi: https://doi.org/10.1371/journal.ppat.1006887
Patterson Ross Z, Klunk J, Fornaciari G, Giuffra V, DuchĂȘne S, Duggan AT, Poinar D, Douglas MW, Eden JS, Holmes EC, Poinar HN. Correction: The paradox of HBV evolution as revealed from a 16th century mummy. PLoS Pathog. 2018 Feb 09;14(2):e1006887. doi: 10.1371/journal.ppat.1006887. eCollection 2018 Feb. PMID: 29425240; PMCID: PMC5806894.
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Fictitious forces and simulated magnetic fields in rotating reference frames.

Physical review letters

Klink WH, Wickramasekara S.
PMID: 24182238
Phys Rev Lett. 2013 Oct 18;111(16):160404. doi: 10.1103/PhysRevLett.111.160404. Epub 2013 Oct 17.

We show that the Wigner-Bargmann program of grounding nonrelativistic quantum mechanics in the unitary projective representations of the Galilei group can be extended to include all noninertial reference frames. The key concept is the Galilean line group, the group...

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Klink WH, Wickramasekara S. Fictitious forces and simulated magnetic fields in rotating reference frames. Phys Rev Lett. 2013;111(16):160404doi: 10.1103/PhysRevLett.111.160404.
Klink, W. H., & Wickramasekara, S. (2013). Fictitious forces and simulated magnetic fields in rotating reference frames. Physical review letters, 111(16), 160404. https://doi.org/10.1103/PhysRevLett.111.160404
Klink, W H, and Wickramasekara, S. "Fictitious forces and simulated magnetic fields in rotating reference frames." Physical review letters vol. 111,16 (2013): 160404. doi: https://doi.org/10.1103/PhysRevLett.111.160404
Klink WH, Wickramasekara S. Fictitious forces and simulated magnetic fields in rotating reference frames. Phys Rev Lett. 2013 Oct 18;111(16):160404. doi: 10.1103/PhysRevLett.111.160404. Epub 2013 Oct 17. PMID: 24182238.
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Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study.

Alzheimer's & dementia (Amsterdam, Netherlands)

Petersen ME, Zhang F, Schupf N, Krinsky-McHale SJ, Hall J, Mapstone M, Cheema A, Silverman W, Lott I, Rafii MS, Handen B, Klunk W, Head E, Christian B, Foroud T, Lai F, Rosas HD, Zaman S, Ances BM, Wang MC, Tycko B, Lee JH, O'Bryant S.
PMID: 32626817
Alzheimers Dement (Amst). 2020 Jun 30;12(1):e12039. doi: 10.1002/dad2.12039. eCollection 2020.

INTRODUCTION: Previously generated serum and plasma proteomic profiles were examined among adults with Down syndrome (DS) to determine whether these profiles could discriminate those with mild cognitive impairment (MCI-DS) and Alzheimer's disease (DS-AD) from those cognitively stable (CS).METHODS: Data...

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Petersen ME, Zhang F, Schupf N, et al. Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study. Alzheimers Dement (Amst). 2020;12(1):e12039doi: 10.1002/dad2.12039.
Petersen, M. E., Zhang, F., Schupf, N., Krinsky-McHale, S. J., Hall, J., Mapstone, M., Cheema, A., Silverman, W., Lott, I., Rafii, M. S., Handen, B., Klunk, W., Head, E., Christian, B., Foroud, T., Lai, F., Rosas, H. D., Zaman, S., Ances, B. M., Wang, M. C., Tycko, B., Lee, J. H., O'Bryant, S. (2020). Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study. Alzheimer's & dementia (Amsterdam, Netherlands), 12(1), e12039. https://doi.org/10.1002/dad2.12039
Petersen, Melissa E, et al. "Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study." Alzheimer's & dementia (Amsterdam, Netherlands) vol. 12,1 (2020): e12039. doi: https://doi.org/10.1002/dad2.12039
Petersen ME, Zhang F, Schupf N, Krinsky-McHale SJ, Hall J, Mapstone M, Cheema A, Silverman W, Lott I, Rafii MS, Handen B, Klunk W, Head E, Christian B, Foroud T, Lai F, Rosas HD, Zaman S, Ances BM, Wang MC, Tycko B, Lee JH, O'Bryant S. Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study. Alzheimers Dement (Amst). 2020 Jun 30;12(1):e12039. doi: 10.1002/dad2.12039. eCollection 2020. PMID: 32626817; PMCID: PMC7327223.
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Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome.

Alzheimer's & dementia (Amsterdam, Netherlands)

Henson RL, Doran E, Christian BT, Handen BL, Klunk WE, Lai F, Lee JH, Rosas HD, Schupf N, Zaman SH, Lott IT, Fagan AM.
PMID: 32671183
Alzheimers Dement (Amst). 2020 Jul 09;12(1):e12057. doi: 10.1002/dad2.12057. eCollection 2020.

INTRODUCTION: Virtually all individuals with Down syndrome (DS) will develop Alzheimer's disease (AD) pathology by age 40. Cerebrospinal fluid (CSF) biomarkers have characterized AD pathology in cohorts of late-onset AD (LOAD) and autosomal-dominant AD (ADAD). Few studies have evaluated...

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Henson RL, Doran E, Christian BT, et al. Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome. Alzheimers Dement (Amst). 2020;12(1):e12057doi: 10.1002/dad2.12057.
Henson, R. L., Doran, E., Christian, B. T., Handen, B. L., Klunk, W. E., Lai, F., Lee, J. H., Rosas, H. D., Schupf, N., Zaman, S. H., Lott, I. T., & Fagan, A. M. (2020). Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome. Alzheimer's & dementia (Amsterdam, Netherlands), 12(1), e12057. https://doi.org/10.1002/dad2.12057
Henson, Rachel L, et al. "Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome." Alzheimer's & dementia (Amsterdam, Netherlands) vol. 12,1 (2020): e12057. doi: https://doi.org/10.1002/dad2.12057
Henson RL, Doran E, Christian BT, Handen BL, Klunk WE, Lai F, Lee JH, Rosas HD, Schupf N, Zaman SH, Lott IT, Fagan AM. Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome. Alzheimers Dement (Amst). 2020 Jul 09;12(1):e12057. doi: 10.1002/dad2.12057. eCollection 2020. PMID: 32671183; PMCID: PMC7346867.
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The use of Centiloids for applying [.

Alzheimer's & dementia (Amsterdam, Netherlands)

Tudorascu DL, Minhas DS, Lao PJ, Betthauser TJ, Yu Z, Laymon CM, Lopresti BJ, Mathis CA, Klunk WE, Handen BL, Christian BT, Cohen AD.
PMID: 30014032
Alzheimers Dement (Amst). 2018 Apr 21;10:332-339. doi: 10.1016/j.dadm.2018.03.006. eCollection 2018.

INTRODUCTION: Centiloid standardization was developed to establish a quantitative outcome measure of amyloid burden that could accommodate the integration of different amyloid positron emission tomography radiotracers or different methods of quantifying the same tracer. The goal of this study...

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Tudorascu DL, Minhas DS, Lao PJ, et al. The use of Centiloids for applying [. Alzheimers Dement (Amst). 2018;10:332-339doi: 10.1016/j.dadm.2018.03.006.
Tudorascu, D. L., Minhas, D. S., Lao, P. J., Betthauser, T. J., Yu, Z., Laymon, C. M., Lopresti, B. J., Mathis, C. A., Klunk, W. E., Handen, B. L., Christian, B. T., & Cohen, A. D. (2018). The use of Centiloids for applying [. Alzheimer's & dementia (Amsterdam, Netherlands), 10332-339. https://doi.org/10.1016/j.dadm.2018.03.006
Tudorascu, Dana L, et al. "The use of Centiloids for applying [." Alzheimer's & dementia (Amsterdam, Netherlands) vol. 10 (2018): 332-339. doi: https://doi.org/10.1016/j.dadm.2018.03.006
Tudorascu DL, Minhas DS, Lao PJ, Betthauser TJ, Yu Z, Laymon CM, Lopresti BJ, Mathis CA, Klunk WE, Handen BL, Christian BT, Cohen AD. The use of Centiloids for applying [. Alzheimers Dement (Amst). 2018 Apr 21;10:332-339. doi: 10.1016/j.dadm.2018.03.006. eCollection 2018. PMID: 30014032; PMCID: PMC6024172.
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A multi-scanner neuroimaging data harmonization using RAVEL and ComBat.

NeuroImage

Eshaghzadeh Torbati M, Minhas DS, Ahmad G, O'Connor EE, Muschelli J, Laymon CM, Yang Z, Cohen AD, Aizenstein HJ, Klunk WE, Christian BT, Hwang SJ, Crainiceanu CM, Tudorascu DL.
PMID: 34736996
Neuroimage. 2021 Nov 01;245:118703. doi: 10.1016/j.neuroimage.2021.118703. Epub 2021 Nov 01.

Modern neuroimaging studies frequently combine data collected from multiple scanners and experimental conditions. Such data often contain substantial technical variability associated with image intensity scale (image intensity scales are not the same in different images) and scanner effects (images...

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Eshaghzadeh Torbati M, Minhas DS, Ahmad G, et al. A multi-scanner neuroimaging data harmonization using RAVEL and ComBat. Neuroimage. 2021;245:118703doi: 10.1016/j.neuroimage.2021.118703.
Eshaghzadeh Torbati, M., Minhas, D. S., Ahmad, G., O'Connor, E. E., Muschelli, J., Laymon, C. M., Yang, Z., Cohen, A. D., Aizenstein, H. J., Klunk, W. E., Christian, B. T., Hwang, S. J., Crainiceanu, C. M., & Tudorascu, D. L. (2021). A multi-scanner neuroimaging data harmonization using RAVEL and ComBat. NeuroImage, 245118703. https://doi.org/10.1016/j.neuroimage.2021.118703
Eshaghzadeh Torbati, Mahbaneh, et al. "A multi-scanner neuroimaging data harmonization using RAVEL and ComBat." NeuroImage vol. 245 (2021): 118703. doi: https://doi.org/10.1016/j.neuroimage.2021.118703
Eshaghzadeh Torbati M, Minhas DS, Ahmad G, O'Connor EE, Muschelli J, Laymon CM, Yang Z, Cohen AD, Aizenstein HJ, Klunk WE, Christian BT, Hwang SJ, Crainiceanu CM, Tudorascu DL. A multi-scanner neuroimaging data harmonization using RAVEL and ComBat. Neuroimage. 2021 Nov 01;245:118703. doi: 10.1016/j.neuroimage.2021.118703. Epub 2021 Nov 01. PMID: 34736996.
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Direct Comparison of the Tau PET Tracers .

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Gogola A, Minhas DS, Villemagne VL, Cohen AD, Mountz JM, Pascoal TA, Laymon CM, Mason NS, Ikonomovic MD, Mathis CA, Snitz BE, Lopez OL, Klunk WE, Lopresti BJ.
PMID: 33863821
J Nucl Med. 2022 Jan;63(1):108-116. doi: 10.2967/jnumed.120.254961. Epub 2021 Apr 16.

Tau PET tracers exhibit varying levels of specific signal and distinct off-target binding patterns that are more diverse than amyloid PET tracers. This study compared 2 frequently used tau PET tracers,

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Gogola A, Minhas DS, Villemagne VL, et al. Direct Comparison of the Tau PET Tracers . J Nucl Med. 2021;63(1):108-116doi: 10.2967/jnumed.120.254961.
Gogola, A., Minhas, D. S., Villemagne, V. L., Cohen, A. D., Mountz, J. M., Pascoal, T. A., Laymon, C. M., Mason, N. S., Ikonomovic, M. D., Mathis, C. A., Snitz, B. E., Lopez, O. L., Klunk, W. E., & Lopresti, B. J. (2022). Direct Comparison of the Tau PET Tracers . Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 63(1), 108-116. https://doi.org/10.2967/jnumed.120.254961
Gogola, Alexandra, et al. "Direct Comparison of the Tau PET Tracers ." Journal of nuclear medicine : official publication, Society of Nuclear Medicine vol. 63,1 (2022): 108-116. doi: https://doi.org/10.2967/jnumed.120.254961
Gogola A, Minhas DS, Villemagne VL, Cohen AD, Mountz JM, Pascoal TA, Laymon CM, Mason NS, Ikonomovic MD, Mathis CA, Snitz BE, Lopez OL, Klunk WE, Lopresti BJ. Direct Comparison of the Tau PET Tracers . J Nucl Med. 2022 Jan;63(1):108-116. doi: 10.2967/jnumed.120.254961. Epub 2021 Apr 16. PMID: 33863821.
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White matter microstructure associations to amyloid burden in adults with Down syndrome.

NeuroImage. Clinical

Bazydlo AM, Zammit MD, Wu M, Lao PJ, Dean DC, Johnson SC, Tudorascu DL, Cohen A, Cody KA, Ances B, Laymon CM, Klunk WE, Zaman S, Handen BL, Hartley SL, Alexander AL, Christian BT.
PMID: 34902714
Neuroimage Clin. 2021 Dec 10;33:102908. doi: 10.1016/j.nicl.2021.102908. Epub 2021 Dec 10.

INTRODUCTION: Individuals with Down syndrome (DS) are at an increased risk of developing Alzheimer's Disease (AD). One of the early underlying mechanisms in AD pathology is the accumulation of amyloid protein plaques, which are deposited in extracellular gray matter...

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Bazydlo AM, Zammit MD, Wu M, et al. White matter microstructure associations to amyloid burden in adults with Down syndrome. Neuroimage Clin. 2021;33:102908doi: 10.1016/j.nicl.2021.102908.
Bazydlo, A. M., Zammit, M. D., Wu, M., Lao, P. J., Dean, D. C., Johnson, S. C., Tudorascu, D. L., Cohen, A., Cody, K. A., Ances, B., Laymon, C. M., Klunk, W. E., Zaman, S., Handen, B. L., Hartley, S. L., Alexander, A. L., & Christian, B. T. (2021). White matter microstructure associations to amyloid burden in adults with Down syndrome. NeuroImage. Clinical, 33102908. https://doi.org/10.1016/j.nicl.2021.102908
Bazydlo, Austin M, et al. "White matter microstructure associations to amyloid burden in adults with Down syndrome." NeuroImage. Clinical vol. 33 (2021): 102908. doi: https://doi.org/10.1016/j.nicl.2021.102908
Bazydlo AM, Zammit MD, Wu M, Lao PJ, Dean DC, Johnson SC, Tudorascu DL, Cohen A, Cody KA, Ances B, Laymon CM, Klunk WE, Zaman S, Handen BL, Hartley SL, Alexander AL, Christian BT. White matter microstructure associations to amyloid burden in adults with Down syndrome. Neuroimage Clin. 2021 Dec 10;33:102908. doi: 10.1016/j.nicl.2021.102908. Epub 2021 Dec 10. PMID: 34902714; PMCID: PMC8672096.
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White matter microstructure associations to amyloid burden in adults with Down syndrome.

NeuroImage. Clinical

Bazydlo AM, Zammit MD, Wu M, Lao PJ, Dean DC, Johnson SC, Tudorascu DL, Cohen A, Cody KA, Ances B, Laymon CM, Klunk WE, Zaman S, Handen BL, Hartley SL, Alexander AL, Christian BT.
PMID: 34902714
Neuroimage Clin. 2021 Dec 10;33:102908. doi: 10.1016/j.nicl.2021.102908. Epub 2021 Dec 10.

INTRODUCTION: Individuals with Down syndrome (DS) are at an increased risk of developing Alzheimer's Disease (AD). One of the early underlying mechanisms in AD pathology is the accumulation of amyloid protein plaques, which are deposited in extracellular gray matter...

Cite
Bazydlo AM, Zammit MD, Wu M, et al. White matter microstructure associations to amyloid burden in adults with Down syndrome. Neuroimage Clin. 2021;33:102908doi: 10.1016/j.nicl.2021.102908.
Bazydlo, A. M., Zammit, M. D., Wu, M., Lao, P. J., Dean, D. C., Johnson, S. C., Tudorascu, D. L., Cohen, A., Cody, K. A., Ances, B., Laymon, C. M., Klunk, W. E., Zaman, S., Handen, B. L., Hartley, S. L., Alexander, A. L., & Christian, B. T. (2021). White matter microstructure associations to amyloid burden in adults with Down syndrome. NeuroImage. Clinical, 33102908. https://doi.org/10.1016/j.nicl.2021.102908
Bazydlo, Austin M, et al. "White matter microstructure associations to amyloid burden in adults with Down syndrome." NeuroImage. Clinical vol. 33 (2021): 102908. doi: https://doi.org/10.1016/j.nicl.2021.102908
Bazydlo AM, Zammit MD, Wu M, Lao PJ, Dean DC, Johnson SC, Tudorascu DL, Cohen A, Cody KA, Ances B, Laymon CM, Klunk WE, Zaman S, Handen BL, Hartley SL, Alexander AL, Christian BT. White matter microstructure associations to amyloid burden in adults with Down syndrome. Neuroimage Clin. 2021 Dec 10;33:102908. doi: 10.1016/j.nicl.2021.102908. Epub 2021 Dec 10. PMID: 34902714; PMCID: PMC8672096.
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