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The formation of a large summertime Saharan dust plume: Convective and synoptic-scale analysis.

Journal of geophysical research. Atmospheres : JGR

Roberts AJ, Knippertz P.
PMID: 25844277
J Geophys Res Atmos. 2014 Feb 27;119(4):1766-1785. doi: 10.1002/2013JD020667. Epub 2014 Feb 26.

Haboobs are dust storms produced by the spreading of evaporatively cooled air from thunderstorms over dusty surfaces and are a major dust uplift process in the Sahara. In this study observations, reanalysis, and a high-resolution simulation using the Weather...

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Roberts AJ, Knippertz P. The formation of a large summertime Saharan dust plume: Convective and synoptic-scale analysis. J Geophys Res Atmos. 2014;119(4):1766-1785doi: 10.1002/2013JD020667.
Roberts, A. J., & Knippertz, P. (2014). The formation of a large summertime Saharan dust plume: Convective and synoptic-scale analysis. Journal of geophysical research. Atmospheres : JGR, 119(4), 1766-1785. https://doi.org/10.1002/2013JD020667
Roberts, A J, and Knippertz, P. "The formation of a large summertime Saharan dust plume: Convective and synoptic-scale analysis." Journal of geophysical research. Atmospheres : JGR vol. 119,4 (2014): 1766-1785. doi: https://doi.org/10.1002/2013JD020667
Roberts AJ, Knippertz P. The formation of a large summertime Saharan dust plume: Convective and synoptic-scale analysis. J Geophys Res Atmos. 2014 Feb 27;119(4):1766-1785. doi: 10.1002/2013JD020667. Epub 2014 Feb 26. PMID: 25844277; PMCID: PMC4379907.
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The importance of rare, high-wind events for dust uplift in northern Africa.

Geophysical research letters

Cowie SM, Marsham JH, Knippertz P.
PMID: 27667872
Geophys Res Lett. 2015 Oct 16;42(19):8208-8215. doi: 10.1002/2015GL065819. Epub 2015 Oct 08.

Dust uplift is a nonlinear thresholded function of wind speed and therefore particularly sensitive to the long tails of observed wind speed probability density functions. This suggests that a few rare high-wind events can contribute substantially to annual dust...

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Cowie SM, Marsham JH, Knippertz P. The importance of rare, high-wind events for dust uplift in northern Africa. Geophys Res Lett. 2015;42(19):8208-8215doi: 10.1002/2015GL065819.
Cowie, S. M., Marsham, J. H., & Knippertz, P. (2015). The importance of rare, high-wind events for dust uplift in northern Africa. Geophysical research letters, 42(19), 8208-8215. https://doi.org/10.1002/2015GL065819
Cowie, Sophie M, et al. "The importance of rare, high-wind events for dust uplift in northern Africa." Geophysical research letters vol. 42,19 (2015): 8208-8215. doi: https://doi.org/10.1002/2015GL065819
Cowie SM, Marsham JH, Knippertz P. The importance of rare, high-wind events for dust uplift in northern Africa. Geophys Res Lett. 2015 Oct 16;42(19):8208-8215. doi: 10.1002/2015GL065819. Epub 2015 Oct 08. PMID: 27667872; PMCID: PMC5020594.
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The role of deep convection and nocturnal low-level jets for dust emission in summertime West Africa: Estimates from convection-permitting simulations.

Journal of geophysical research. Atmospheres : JGR

Heinold B, Knippertz P, Marsham JH, Fiedler S, Dixon NS, Schepanski K, Laurent B, Tegen I.
PMID: 25893153
J Geophys Res Atmos. 2013 May 27;118(10):4385-4400. doi: 10.1002/jgrd.50402. Epub 2013 May 29.

[1] Convective cold pools and the breakdown of nocturnal low-level jets (NLLJs) are key meteorological drivers of dust emission over summertime West Africa, the world's largest dust source. This study is the first to quantify their relative contributions and...

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Heinold B, Knippertz P, Marsham JH, et al. The role of deep convection and nocturnal low-level jets for dust emission in summertime West Africa: Estimates from convection-permitting simulations. J Geophys Res Atmos. 2013;118(10):4385-4400doi: 10.1002/jgrd.50402.
Heinold, B., Knippertz, P., Marsham, J. H., Fiedler, S., Dixon, N. S., Schepanski, K., Laurent, B., & Tegen, I. (2013). The role of deep convection and nocturnal low-level jets for dust emission in summertime West Africa: Estimates from convection-permitting simulations. Journal of geophysical research. Atmospheres : JGR, 118(10), 4385-4400. https://doi.org/10.1002/jgrd.50402
Heinold, B, et al. "The role of deep convection and nocturnal low-level jets for dust emission in summertime West Africa: Estimates from convection-permitting simulations." Journal of geophysical research. Atmospheres : JGR vol. 118,10 (2013): 4385-4400. doi: https://doi.org/10.1002/jgrd.50402
Heinold B, Knippertz P, Marsham JH, Fiedler S, Dixon NS, Schepanski K, Laurent B, Tegen I. The role of deep convection and nocturnal low-level jets for dust emission in summertime West Africa: Estimates from convection-permitting simulations. J Geophys Res Atmos. 2013 May 27;118(10):4385-4400. doi: 10.1002/jgrd.50402. Epub 2013 May 29. PMID: 25893153; PMCID: PMC4394720.
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Identifying errors in dust models from data assimilation.

Geophysical research letters

Pope RJ, Marsham JH, Knippertz P, Brooks ME, Roberts AJ.
PMID: 27840459
Geophys Res Lett. 2016 Sep 16;43(17):9270-9279. doi: 10.1002/2016GL070621. Epub 2016 Sep 03.

Airborne mineral dust is an important component of the Earth system and is increasingly predicted prognostically in weather and climate models. The recent development of data assimilation for remotely sensed aerosol optical depths (AODs) into models offers a new...

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Pope RJ, Marsham JH, Knippertz P, et al. Identifying errors in dust models from data assimilation. Geophys Res Lett. 2016;43(17):9270-9279doi: 10.1002/2016GL070621.
Pope, R. J., Marsham, J. H., Knippertz, P., Brooks, M. E., & Roberts, A. J. (2016). Identifying errors in dust models from data assimilation. Geophysical research letters, 43(17), 9270-9279. https://doi.org/10.1002/2016GL070621
Pope, R J, et al. "Identifying errors in dust models from data assimilation." Geophysical research letters vol. 43,17 (2016): 9270-9279. doi: https://doi.org/10.1002/2016GL070621
Pope RJ, Marsham JH, Knippertz P, Brooks ME, Roberts AJ. Identifying errors in dust models from data assimilation. Geophys Res Lett. 2016 Sep 16;43(17):9270-9279. doi: 10.1002/2016GL070621. Epub 2016 Sep 03. PMID: 27840459; PMCID: PMC5082526.
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Add-on Cannabidiol Treatment for Drug-Resistant Seizures in Tuberous Sclerosis Complex: A Placebo-Controlled Randomized Clinical Trial.

JAMA neurology

Thiele EA, Bebin EM, Bhathal H, Jansen FE, Kotulska K, Lawson JA, O'Callaghan FJ, Wong M, Sahebkar F, Checketts D, Knappertz V.
PMID: 33346789
JAMA Neurol. 2021 Mar 01;78(3):285-292. doi: 10.1001/jamaneurol.2020.4607.

IMPORTANCE: Efficacy of cannabidiol has been demonstrated in seizures associated with Lennox-Gastaut and Dravet syndromes but appears not yet to have been established in conditions with primarily focal seizures, such as tuberous sclerosis complex (TSC).OBJECTIVE: To evaluate efficacy and...

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Thiele EA, Bebin EM, Bhathal H, et al. Add-on Cannabidiol Treatment for Drug-Resistant Seizures in Tuberous Sclerosis Complex: A Placebo-Controlled Randomized Clinical Trial. JAMA Neurol. 2021;78(3):285-292doi: 10.1001/jamaneurol.2020.4607.
Thiele, E. A., Bebin, E. M., Bhathal, H., Jansen, F. E., Kotulska, K., Lawson, J. A., O'Callaghan, F. J., Wong, M., Sahebkar, F., Checketts, D., Knappertz, V. (2021). Add-on Cannabidiol Treatment for Drug-Resistant Seizures in Tuberous Sclerosis Complex: A Placebo-Controlled Randomized Clinical Trial. JAMA neurology, 78(3), 285-292. https://doi.org/10.1001/jamaneurol.2020.4607
Thiele, Elizabeth A, et al. "Add-on Cannabidiol Treatment for Drug-Resistant Seizures in Tuberous Sclerosis Complex: A Placebo-Controlled Randomized Clinical Trial." JAMA neurology vol. 78,3 (2021): 285-292. doi: https://doi.org/10.1001/jamaneurol.2020.4607
Thiele EA, Bebin EM, Bhathal H, Jansen FE, Kotulska K, Lawson JA, O'Callaghan FJ, Wong M, Sahebkar F, Checketts D, Knappertz V. Add-on Cannabidiol Treatment for Drug-Resistant Seizures in Tuberous Sclerosis Complex: A Placebo-Controlled Randomized Clinical Trial. JAMA Neurol. 2021 Mar 01;78(3):285-292. doi: 10.1001/jamaneurol.2020.4607. PMID: 33346789; PMCID: PMC7754080.
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Cause of death in MS: long-term follow-up of a randomised cohort, 21 years after the start of the pivotal IFNβ-1b study.

BMJ open

Goodin DS, Ebers GC, Cutter G, Cook SD, O'Donnell T, Reder AT, Kremenchutzky M, Oger J, Rametta M, Beckmann K, Knappertz V.
PMID: 23204140
BMJ Open. 2012 Nov 30;2(6). doi: 10.1136/bmjopen-2012-001972. Print 2012.

OBJECTIVES: Compared with controls, multiple sclerosis (MS) patients die, on average, 7-14 years prematurely. Previously, we reported that, 21 years after their participation in the pivotal randomised, controlled trial (RCT) of interferon β-1b, mortality was reduced by 46-47% in...

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Goodin DS, Ebers GC, Cutter G, et al. Cause of death in MS: long-term follow-up of a randomised cohort, 21 years after the start of the pivotal IFNβ-1b study. BMJ Open. 2012;2(6)doi: 10.1136/bmjopen-2012-001972.
Goodin, D. S., Ebers, G. C., Cutter, G., Cook, S. D., O'Donnell, T., Reder, A. T., Kremenchutzky, M., Oger, J., Rametta, M., Beckmann, K., & Knappertz, V. (2012). Cause of death in MS: long-term follow-up of a randomised cohort, 21 years after the start of the pivotal IFNβ-1b study. BMJ open, 2(6), . https://doi.org/10.1136/bmjopen-2012-001972
Goodin, Douglas S, et al. "Cause of death in MS: long-term follow-up of a randomised cohort, 21 years after the start of the pivotal IFNβ-1b study." BMJ open vol. 2,6 (2012). doi: https://doi.org/10.1136/bmjopen-2012-001972
Goodin DS, Ebers GC, Cutter G, Cook SD, O'Donnell T, Reder AT, Kremenchutzky M, Oger J, Rametta M, Beckmann K, Knappertz V. Cause of death in MS: long-term follow-up of a randomised cohort, 21 years after the start of the pivotal IFNβ-1b study. BMJ Open. 2012 Nov 30;2(6). doi: 10.1136/bmjopen-2012-001972. Print 2012. PMID: 23204140; PMCID: PMC3533062.
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Fractional Montgomery effect: a self-imaging phenomenon.

Journal of the Optical Society of America. A, Optics, image science, and vision

Lohmann AW, Knuppertz H, Jahns J.
PMID: 16134844
J Opt Soc Am A Opt Image Sci Vis. 2005 Aug;22(8):1500-8. doi: 10.1364/josaa.22.001500.

Self-imaging means image formation without the help of a lens or any other device between object and image. There are three versions of self-imaging: the classical Talbot effect (1836), the fractional Talbot effect, and the Montgomery effect (1967). Talbot...

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Lohmann AW, Knuppertz H, Jahns J. Fractional Montgomery effect: a self-imaging phenomenon. J Opt Soc Am A Opt Image Sci Vis. 2005;22(8):1500-8doi: 10.1364/josaa.22.001500.
Lohmann, A. W., Knuppertz, H., & Jahns, J. (2005). Fractional Montgomery effect: a self-imaging phenomenon. Journal of the Optical Society of America. A, Optics, image science, and vision, 22(8), 1500-8. https://doi.org/10.1364/josaa.22.001500
Lohmann, Adolf W, et al. "Fractional Montgomery effect: a self-imaging phenomenon." Journal of the Optical Society of America. A, Optics, image science, and vision vol. 22,8 (2005): 1500-8. doi: https://doi.org/10.1364/josaa.22.001500
Lohmann AW, Knuppertz H, Jahns J. Fractional Montgomery effect: a self-imaging phenomenon. J Opt Soc Am A Opt Image Sci Vis. 2005 Aug;22(8):1500-8. doi: 10.1364/josaa.22.001500. PMID: 16134844.
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Climatology of nocturnal low-level jets over North Africa and implications for modeling mineral dust emission.

Journal of geophysical research. Atmospheres : JGR

Fiedler S, Schepanski K, Heinold B, Knippertz P, Tegen I.
PMID: 25893154
J Geophys Res Atmos. 2013 Jun 27;118(12):6100-6121. doi: 10.1002/jgrd.50394. Epub 2013 Jun 21.

[1] This study presents the first climatology for the dust emission amount associated with Nocturnal Low-Level Jets (NLLJs) in North Africa. These wind speed maxima near the top of the nocturnal boundary layer can generate near-surface peak winds due...

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Fiedler S, Schepanski K, Heinold B, et al. Climatology of nocturnal low-level jets over North Africa and implications for modeling mineral dust emission. J Geophys Res Atmos. 2013;118(12):6100-6121doi: 10.1002/jgrd.50394.
Fiedler, S., Schepanski, K., Heinold, B., Knippertz, P., & Tegen, I. (2013). Climatology of nocturnal low-level jets over North Africa and implications for modeling mineral dust emission. Journal of geophysical research. Atmospheres : JGR, 118(12), 6100-6121. https://doi.org/10.1002/jgrd.50394
Fiedler, S, et al. "Climatology of nocturnal low-level jets over North Africa and implications for modeling mineral dust emission." Journal of geophysical research. Atmospheres : JGR vol. 118,12 (2013): 6100-6121. doi: https://doi.org/10.1002/jgrd.50394
Fiedler S, Schepanski K, Heinold B, Knippertz P, Tegen I. Climatology of nocturnal low-level jets over North Africa and implications for modeling mineral dust emission. J Geophys Res Atmos. 2013 Jun 27;118(12):6100-6121. doi: 10.1002/jgrd.50394. Epub 2013 Jun 21. PMID: 25893154; PMCID: PMC4394707.
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Survival in commercially insured multiple sclerosis patients and comparator subjects in the U.S.

Multiple sclerosis and related disorders

Kaufman DW, Reshef S, Golub HL, Peucker M, Corwin MJ, Goodin DS, Knappertz V, Pleimes D, Cutter G.
PMID: 25876474
Mult Scler Relat Disord. 2014 May;3(3):364-71. doi: 10.1016/j.msard.2013.12.003. Epub 2013 Dec 25.

OBJECTIVE: Compare survival in patients with multiple sclerosis (MS) from a U.S. commercial health insurance database with a matched cohort of non-MS subjects.METHODS: 30,402 MS patients and 89,818 non-MS subjects (comparators) in the OptumInsight Research (OIR) database from 1996...

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Kaufman DW, Reshef S, Golub HL, et al. Survival in commercially insured multiple sclerosis patients and comparator subjects in the U.S. Mult Scler Relat Disord. 2013;3(3):364-71doi: 10.1016/j.msard.2013.12.003.
Kaufman, D. W., Reshef, S., Golub, H. L., Peucker, M., Corwin, M. J., Goodin, D. S., Knappertz, V., Pleimes, D., & Cutter, G. (2014). Survival in commercially insured multiple sclerosis patients and comparator subjects in the U.S. Multiple sclerosis and related disorders, 3(3), 364-71. https://doi.org/10.1016/j.msard.2013.12.003
Kaufman, D W, et al. "Survival in commercially insured multiple sclerosis patients and comparator subjects in the U.S." Multiple sclerosis and related disorders vol. 3,3 (2014): 364-71. doi: https://doi.org/10.1016/j.msard.2013.12.003
Kaufman DW, Reshef S, Golub HL, Peucker M, Corwin MJ, Goodin DS, Knappertz V, Pleimes D, Cutter G. Survival in commercially insured multiple sclerosis patients and comparator subjects in the U.S. Mult Scler Relat Disord. 2014 May;3(3):364-71. doi: 10.1016/j.msard.2013.12.003. Epub 2013 Dec 25. PMID: 25876474.
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Laquinimod Safety Profile: Pooled Analyses from the ALLEGRO and BRAVO Trials.

International journal of MS care

Sørensen PS, Comi G, Vollmer TL, Montalban X, Kappos L, Dadon Y, Gorfine T, Margalit M, Sasson N, Rubinchick S, Knappertz V.
PMID: 28243182
Int J MS Care. 2017 Jan-Feb;19(1):16-24. doi: 10.7224/1537-2073.2015-024.

BACKGROUND: Laquinimod 0.6 mg is a once-daily, oral, disease-modifying therapy in development for the treatment of multiple sclerosis (MS) that was investigated in two double-blind, placebo-controlled, phase 3 trials: ALLEGRO and BRAVO.METHODS: Data from these studies were pooled to...

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Sørensen PS, Comi G, Vollmer TL, et al. Laquinimod Safety Profile: Pooled Analyses from the ALLEGRO and BRAVO Trials. Int J MS Care. 2017;19(1):16-24doi: 10.7224/1537-2073.2015-024.
Sørensen, P. S., Comi, G., Vollmer, T. L., Montalban, X., Kappos, L., Dadon, Y., Gorfine, T., Margalit, M., Sasson, N., Rubinchick, S., & Knappertz, V. (2017). Laquinimod Safety Profile: Pooled Analyses from the ALLEGRO and BRAVO Trials. International journal of MS care, 19(1), 16-24. https://doi.org/10.7224/1537-2073.2015-024
Sørensen, Per Soelberg, et al. "Laquinimod Safety Profile: Pooled Analyses from the ALLEGRO and BRAVO Trials." International journal of MS care vol. 19,1 (2017): 16-24. doi: https://doi.org/10.7224/1537-2073.2015-024
Sørensen PS, Comi G, Vollmer TL, Montalban X, Kappos L, Dadon Y, Gorfine T, Margalit M, Sasson N, Rubinchick S, Knappertz V. Laquinimod Safety Profile: Pooled Analyses from the ALLEGRO and BRAVO Trials. Int J MS Care. 2017 Jan-Feb;19(1):16-24. doi: 10.7224/1537-2073.2015-024. PMID: 28243182; PMCID: PMC5315319.
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Time course of glatiramer acetate efficacy in patients with RRMS in the GALA study.

Neurology(R) neuroimmunology & neuroinflammation

Davis MD, Ashtamker N, Steinerman JR, Knappertz V.
PMID: 28210662
Neurol Neuroimmunol Neuroinflamm. 2017 Feb 08;4(2):e327. doi: 10.1212/NXI.0000000000000327. eCollection 2017 Mar.

OBJECTIVE: To determine the time to efficacy onset of glatiramer acetate (GA) 40 mg/mL 3-times-weekly formulation (GA40).METHODS: This post hoc analysis of data from the 1-year, double-blind, placebo-controlled phase of the Glatiramer Acetate Low-Frequency Administration study (NCT01067521) of GA40...

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Davis MD, Ashtamker N, Steinerman JR, et al. Time course of glatiramer acetate efficacy in patients with RRMS in the GALA study. Neurol Neuroimmunol Neuroinflamm. 2017;4(2):e327doi: 10.1212/NXI.0000000000000327.
Davis, M. D., Ashtamker, N., Steinerman, J. R., & Knappertz, V. (2017). Time course of glatiramer acetate efficacy in patients with RRMS in the GALA study. Neurology(R) neuroimmunology & neuroinflammation, 4(2), e327. https://doi.org/10.1212/NXI.0000000000000327
Davis, Mat D, et al. "Time course of glatiramer acetate efficacy in patients with RRMS in the GALA study." Neurology(R) neuroimmunology & neuroinflammation vol. 4,2 (2017): e327. doi: https://doi.org/10.1212/NXI.0000000000000327
Davis MD, Ashtamker N, Steinerman JR, Knappertz V. Time course of glatiramer acetate efficacy in patients with RRMS in the GALA study. Neurol Neuroimmunol Neuroinflamm. 2017 Feb 08;4(2):e327. doi: 10.1212/NXI.0000000000000327. eCollection 2017 Mar. PMID: 28210662; PMCID: PMC5299631.
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Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells.

Frontiers in immunology

Hammer A, Waschbisch A, Knippertz I, Zinser E, Berg J, Jörg S, Kuhbandner K, David C, Pi J, Bayas A, Lee DH, Haghikia A, Gold R, Steinkasserer A, Linker RA.
PMID: 29312359
Front Immunol. 2017 Dec 22;8:1922. doi: 10.3389/fimmu.2017.01922. eCollection 2017.

To date, the intracellular signaling pathways involved in dendritic cell (DC) function are poorly understood. The antioxidative transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) has been shown to affect maturation, function, and subsequent DC-mediated T cell responses of...

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Hammer A, Waschbisch A, Knippertz I, et al. Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells. Front Immunol. 2017;8:1922doi: 10.3389/fimmu.2017.01922.
Hammer, A., Waschbisch, A., Knippertz, I., Zinser, E., Berg, J., Jörg, S., Kuhbandner, K., David, C., Pi, J., Bayas, A., Lee, D. H., Haghikia, A., Gold, R., Steinkasserer, A., & Linker, R. A. (2017). Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells. Frontiers in immunology, 81922. https://doi.org/10.3389/fimmu.2017.01922
Hammer, Anna, et al. "Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells." Frontiers in immunology vol. 8 (2017): 1922. doi: https://doi.org/10.3389/fimmu.2017.01922
Hammer A, Waschbisch A, Knippertz I, Zinser E, Berg J, Jörg S, Kuhbandner K, David C, Pi J, Bayas A, Lee DH, Haghikia A, Gold R, Steinkasserer A, Linker RA. Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells. Front Immunol. 2017 Dec 22;8:1922. doi: 10.3389/fimmu.2017.01922. eCollection 2017. PMID: 29312359; PMCID: PMC5744071.
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