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Showing 1 to 12 of 27 entries
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Contemporary Management of Localized Resectable Pancreatic Cancer.

Cancers

Kommalapati A, Tella SH, Goyal G, Ma WW, Mahipal A.
PMID: 29361690
Cancers (Basel). 2018 Jan 20;10(1). doi: 10.3390/cancers10010024.

Pancreatic cancer is the third most common cause of cancer deaths in the United States. Surgical resection with negative margins still constitutes the cornerstone of potentially curative therapy, but is possible only in 15-20% of patients at the time...

Profile of Abaloparatide and Its Potential in the Treatment of Postmenopausal Osteoporosis.

Cureus

Tella SH, Kommalapati A, Correa R.
PMID: 28680788
Cureus. 2017 May 31;9(5):e1300. doi: 10.7759/cureus.1300.

Abaloparatide (previously known as BA058) is a synthetic 34-amino acid peptide and novel selective activator of parathyroid hormone receptor 1 (PTHR1) currently under development as a new anabolic agent in the management of osteoporosis. This paper reviews the profile...

Clinicopathological features and outcomes of fibrolamellar hepatocellular carcinoma.

Journal of gastrointestinal oncology

Chakrabarti S, Tella SH, Kommalapati A, Huffman BM, Yadav S, Riaz IB, Goyal G, Mody K, Borad M, Cleary S, Smoot RL, Mahipal A.
PMID: 31183207
J Gastrointest Oncol. 2019 Jun;10(3):554-561. doi: 10.21037/jgo.2019.01.35.

BACKGROUND: Clinicopathological features and the outcomes of patients with fibrolamellar hepatocellular carcinoma (FLHCC) are not clearly defined.METHODS: Data were collected by retrospective chart review on 42 patients with FLHCC treated between 1990 and 2017 at Mayo Clinic.RESULTS: Of 42...

Alliance A011801 (compassHER2 RD): postneoadjuvant T-DM1 + tucatinib/placebo in patients with residual HER2-positive invasive breast cancer.

Future oncology (London, England)

O'Sullivan CC, Ballman KV, McCall L, Kommalapati A, Zemla T, Weiss A, Mitchell M, Blinder V, Tung NM, Irvin WJ, Lee M, Goetz MP, Symmans WF, Borges VF, Krop I, Carey LA, Partridge AH.
PMID: 34636255
Future Oncol. 2021 Dec;17(34):4665-4676. doi: 10.2217/fon-2021-0753. Epub 2021 Oct 12.

This report describes the rationale, purpose and design of A011801 (CompassHER2 RD), an ongoing prospective, multicenter, Phase III randomized trial. Eligible patients in the United States (US) and Canada with high-risk (defined as ER-negative and/or node-positive) HER2-positive (HER2+) residual...

Aspirin and Statin Use and the Risk of Gallbladder Cancer.

Cancers

Prasai K, Tella SH, Yadav S, Kommalapati A, Mara K, Mady M, Hassan MA, Wongjarupong N, Rodriguez-Payan N, Borad M, Patel T, Roberts LR, Mahipal A.
PMID: 33803387
Cancers (Basel). 2021 Mar 09;13(5). doi: 10.3390/cancers13051186.

Aspirin and statin drugs have been associated with reduced risk of several gastrointestinal cancers, but their association with gallbladder cancer (GBC) has not been well established. We evaluated the association of aspirin and statins with the risk of GBC....

9-Ethynyl noscapine induces G2/M arrest and apoptosis by disrupting tubulin polymerization in cervical cancer.

Drug development research

Nagireddy PKR, Kumar D, Kommalapati VK, Pedapati RK, Kojja V, Tangutur AD, Kantevari S.
PMID: 34612529
Drug Dev Res. 2021 Oct 06; doi: 10.1002/ddr.21888. Epub 2021 Oct 06.

Noscapine is a phthalide isoquinoline alkaloid present in the latex of Papaver somniferum and has demonstrated potent antitumor activity in various cancer models. Structural changes in the core molecule of noscapine architecture have produced a number of potent analogs....

Age estimation by assessment of dentin translucency in single rooted permanent teeth.

Journal of international oral health : JIOH

Kattappagari KK, Kommalapati RK, Katuri D, Murakonda RS, Chitturi RT, Reddy BV.
PMID: 25628481
J Int Oral Health. 2014 Nov-Dec;6(6):37-40.

BACKGROUND: To estimate the age by evaluating the area and length of dentin translucency in single-rooted ground sections of extracted teeth using digital Vernier caliper and stereomicroscope.MATERIALS AND METHODS: Ground sections of single rooted permanent anterior teeth were made...

Cost-effectiveness in managing skeletal related events in breast cancer: a strategy of less-intense dosing schedule of bone modifying agents.

Translational cancer research

Tella SH, Kommalapati A, Singhi RK.
PMID: 29863174
Transl Cancer Res. 2018 Feb;7:S81-S84. doi: 10.21037/tcr.2018.01.07.

No abstract available.

Alliance A011801 (compassHER2 RD): postneoadjuvant T-DM1 + tucatinib/placebo in patients with residual HER2-positive invasive breast cancer.

Future oncology (London, England)

O'Sullivan CC, Ballman KV, McCall L, Kommalapati A, Zemla T, Weiss A, Mitchell M, Blinder V, Tung NM, Irvin WJ, Lee M, Goetz MP, Symmans WF, Borges VF, Krop I, Carey LA, Partridge AH.
PMID: 34636255
Future Oncol. 2021 Dec;17(34):4665-4676. doi: 10.2217/fon-2021-0753. Epub 2021 Oct 12.

This report describes the rationale, purpose and design of A011801 (CompassHER2 RD), an ongoing prospective, multicenter, Phase III randomized trial. Eligible patients in the United States (US) and Canada with high-risk (defined as ER-negative and/or node-positive) HER2-positive (HER2+) residual...

Imidazo[2,1-.

ACS omega

Nagireddy PKR, Kommalapati VK, Siva Krishna V, Sriram D, Tangutur AD, Kantevari S.
PMID: 31763563
ACS Omega. 2019 Nov 05;4(21):19382-19398. doi: 10.1021/acsomega.9b02789. eCollection 2019 Nov 19.

Noscapine, a phthalide isoquinoline alkaloid isolated from the opium poppy

Quisinostat mediated autophagy is associated with differentiation in neuroblastoma SK-N-SH cells.

Molecular biology reports

Kommalapati VK, Kumar D, Tangutur AD.
PMID: 34125328
Mol Biol Rep. 2021 May;48(5):4973-4979. doi: 10.1007/s11033-021-06481-z. Epub 2021 Jun 14.

Neuroblastoma (NB) is the most common childhood cancer that arises from the sympathetic nervous system. NB is characterized by poor prognosis. One of the strategies to control NB is activating the differentiation process in undifferentiated NB cells. Many differentiating...

Immune Check Point Inhibitors in Cancer Therapy: Beware of "Friendly Fire" Effect.

Research & reviews. Journal of hospital and clinical pharmacy

Kommalapati A, Sikder S, Tella SH.
PMID: 29291253
Res Rev J Hosp Clin Pharm. 2017 Jul;3(2):5-6. Epub 2017 Jun 08.

No abstract available.

Showing 1 to 12 of 27 entries