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Showing 1 to 12 of 173 entries
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Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors.

EJNMMI research

van Wieringen JP, Michel MC, Janssen HM, Janssen AG, Elsinga PH, Booij J.
PMID: 25977878
EJNMMI Res. 2014 Oct 07;4:53. doi: 10.1186/s13550-014-0053-3. eCollection 2014.

BACKGROUND: Dopamine D2/3 receptor (D2/3R) agonist radiopharmaceuticals are considered superior to antagonists to detect dopamine release, e.g. induced by amphetamines. Agonists bind preferentially to the high-affinity state of the dopamine D2R, which has been proposed as the reason why...

The diagnostic accuracy of dopamine transporter SPECT imaging to detect nigrostriatal cell loss in patients with Parkinson's disease or clinically uncertain parkinsonism: a systematic review.

EJNMMI research

Suwijn SR, van Boheemen CJ, de Haan RJ, Tissingh G, Booij J, de Bie RM.
PMID: 25853018
EJNMMI Res. 2015 Mar 17;5:12. doi: 10.1186/s13550-015-0087-1. eCollection 2015.

In specialized movement disorder centers, Parkinson's disease (PD) is wrongly diagnosed in 6 to 25% of cases. To improve the accuracy of the clinical diagnosis, it is necessary to have a reliable and practical reference standard. Dopamine transporter single-photon...

Synthesis and evaluation in rats of homologous series of [(18)F]-labeled dopamine D 2/3 receptor agonists based on the 2-aminomethylchroman scaffold as potential PET tracers.

EJNMMI research

Shalgunov V, van Wieringen JP, Janssen HM, Fransen PM, Dierckx RA, Michel MC, Booij J, Elsinga PH.
PMID: 26205538
EJNMMI Res. 2015 Dec;5(1):119. doi: 10.1186/s13550-015-0119-x. Epub 2015 Jul 25.

BACKGROUND: Agonist positron emission tomography (PET) tracers for dopamine D2/3 receptors (D2/3Rs) offer greater sensitivity to changes in endogenous dopamine levels than D2/3R antagonist tracers. D2/3R agonist tracers currently available for clinical research are labeled with the short-lived isotope...

SERT-to-DAT ratios in early Parkinson's disease do not correlate with the development of dyskinesias.

EJNMMI research

Suwijn SR, Berendse HW, Verschuur CV, Winogrodzka A, de Bie RM, Booij J.
PMID: 23738774
EJNMMI Res. 2013 Jun 05;3(1):44. doi: 10.1186/2191-219X-3-44.

BACKGROUND: Although the treatment of Parkinson's disease (PD) is very effective, in the course of the disease, 40% to 60% of patients develop dyskinesias. The pathophysiology of dyskinesias is still unclear. Results of preclinical research suggest that uptake and...

Substrate Utilization by Suspension Cultures and Somatic Embryos of Daucus carota L. Measured by C NMR.

Plant physiology

Dijkema C, de Vries SC, Booij H, Schaafsma TJ, van Kammen A.
PMID: 16666463
Plant Physiol. 1988 Dec;88(4):1332-7. doi: 10.1104/pp.88.4.1332.

The uptake and utilization of sucrose by embryogenic suspension cultures of carrot (Daucus carota L.) growing in the presence of 2,4-D and by somatic embryos derived from these cultures was monitored using (13)C nuclear magnetic resonance. The exogeneously supplied...

Strong intermolecular association between short poly(ethacrylic acid) chains in aqueous solutions.

The journal of physical chemistry. B

Peljhan S, Zagar E, Cerkovnik J, Kogej K.
PMID: 19193057
J Phys Chem B. 2009 Feb 26;113(8):2300-9. doi: 10.1021/jp806312u.

The behavior of poly(alpha-ethylacrylic acid), PEA, was studied in aqueous solutions at 25 degrees C and at a polymer concentration 0.01 mol carboxyl groups/L by conductometric, potentiometric, calorimetric, and fluorescence measurements. PEA chains were characterized for molar mass, eventual...

Acquisition of embryogenic potential in carrot cell-suspension cultures.

Planta

de Vries SC, Booij H, Meyerink P, Huisman G, Wilde HD, Thomas TL, van Kammen A.
PMID: 24220773
Planta. 1988 Nov;176(2):196-204. doi: 10.1007/BF00392445.

Embryogenic suspension cultures of domesticated carrot (Daucus carota L.) are characterized by the presence of proembryogenic masses (PEMs) from which somatic embryos develop under conditions of low cell density in the absence of phytohormones. A culture system, referred to...

Imaging of serotonin transporters with [123I]FP-CIT SPECT in the human hypothalamus.

EJNMMI research

Borgers AJ, Alkemade A, Van de Giessen EM, Drent ML, Booij J, Bisschop PH, Fliers E.
PMID: 23618227
EJNMMI Res. 2013 Apr 25;3(1):34. doi: 10.1186/2191-219X-3-34.

BACKGROUND: Serotonergic neurons in the rodent hypothalamus are implicated in key neuroendocrine and metabolic functions, including circadian rhythmicity. However, the assessment of the serotonergic system in the human hypothalamus in vivo is difficult as delineation of the hypothalamus is...

Performance evaluation of a novel brain-dedicated SPECT system.

EJNMMI physics

Stam MK, Verwer EE, Booij J, Adriaanse SM, de Bruin CM, de Wit TC.
PMID: 29492787
EJNMMI Phys. 2018 Mar 01;5(1):4. doi: 10.1186/s40658-018-0203-1.

No abstract available.

Erratum to: The need of standardization and of large clinical studies in an emerging indication of [18 F]FDG PET: the autoimmune encephalitis.

European journal of nuclear medicine and molecular imaging

Morbelli S, Arbizu J, Booij J, Chen MK, Chetelat G, Cross DJ, Djekidel M, Drzezga A, Ekmekcioglu O, Garibotto V, Hesse S, Ishii K, Jafari L, Lammertsma AA, Law I, Mathews D, Minoshima S, Mosci K, Pagani M, Pappata S, Silverman DH, Signore A, Van De Giessen E, Villemagne V, Barthel H.
PMID: 27987029
Eur J Nucl Med Mol Imaging. 2017 Mar;44(3):559-560. doi: 10.1007/s00259-016-3598-8.

No abstract available.

Size distributions of droplets produced by ultrasonic nebulizers.

Scientific reports

Kooij S, Astefanei A, Corthals GL, Bonn D.
PMID: 30992484
Sci Rep. 2019 Apr 16;9(1):6128. doi: 10.1038/s41598-019-42599-8.

In many applications where small, similar-sized droplets are needed, ultrasonic nebulizers are employed. Little is known about the mechanism of nebulization, for example about what determines the median droplet size. Even less understood, is the droplet size distribution, which...

Dealing with Flow Effects on the Uptake of Polar Compounds by Passive Samplers.

Environmental science & technology

Fauvelle V, Kaserzon SL, Montero N, Lissalde S, Allan IJ, Mills G, Mazzella N, Mueller JF, Booij K.
PMID: 28225255
Environ Sci Technol. 2017 Mar 07;51(5):2536-2537. doi: 10.1021/acs.est.7b00558. Epub 2017 Feb 22.

No abstract available.

Showing 1 to 12 of 173 entries