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Showing 1 to 12 of 19 entries
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Metastatic Uveal Melanoma: Treatment Strategies and Survival-Results from the Dutch Melanoma Treatment Registry.

Cancers

Jochems A, van der Kooij MK, Fiocco M, Schouwenburg MG, Aarts MJ, van Akkooi AC, van den Berkmortel FWPJ, Blank CU, van den Eertwegh AJM, Franken MG, de Groot JB, Haanen JBAG, Hospers GAP, Koornstra RH, Kruit WHJ, Louwman M, Piersma D, van Rijn RS, Suijkerbuijk KPM, Ten Tije AJ, Vreugdenhil G, Wouters MWJM, van Zeijl MCT, van der Hoeven KJM, Kapiteijn E.
PMID: 31323802
Cancers (Basel). 2019 Jul 18;11(7). doi: 10.3390/cancers11071007.

Uveal melanoma (UM) is the most common primary intraocular tumor in adults. Up to 50% of UM patients will develop metastases. We present data of 175 metastatic UM patients diagnosed in the Netherlands between July 2012 and March 2018....

Risk and Time Pattern of Recurrences After Local Endoscopic Resection of T1 Colorectal Cancer: A Meta-analysis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Dang H, Dekkers N, le Cessie S, van Hooft JE, van Leerdam ME, Oldenburg PP, Flothuis L, Schoones JW, Langers AMJ, Hardwick JCH, van der Kraan J, Boonstra JJ.
PMID: 33271339
Clin Gastroenterol Hepatol. 2022 Feb;20(2):e298-e314. doi: 10.1016/j.cgh.2020.11.032. Epub 2020 Dec 01.

BACKGROUND & AIMS: Growing numbers of patients with T1 CRC are being treated with local endoscopic resection only and as a result, the need for optimization of surveillance strategies for these patients also increases. We aimed to estimate the...

Towards Personalized Treatment Strategies for Esophageal Adenocarcinoma; A Review on the Molecular Characterization of Esophageal Adenocarcinoma and Current Research Efforts on Individualized Curative Treatment Regimens.

Cancers

Hoefnagel SJM, Boonstra JJ, Russchen MJAM, Krishnadath KK.
PMID: 34638363
Cancers (Basel). 2021 Sep 29;13(19). doi: 10.3390/cancers13194881.

Esophageal cancers confer a major health challenge and are highly aggressive malignancies with poor prognosis. Esophageal adenocarcinoma (EAC) is one of the two major histopathological subtypes of esophageal cancer. Despite advances in treatment modalities, the prognosis of patients with...

Ipilimumab administered to metastatic melanoma patients who progressed after dendritic cell vaccination.

Oncoimmunology

Boudewijns S, Koornstra RH, Westdorp H, Schreibelt G, van den Eertwegh AJ, Geukes Foppen MH, Haanen JB, de Vries IJ, Figdor CG, Bol KF, Gerritsen WR.
PMID: 27622070
Oncoimmunology. 2016 Jun 17;5(8):e1201625. doi: 10.1080/2162402X.2016.1201625. eCollection 2016 Aug.

BACKGROUND: Ipilimumab has proven to be effective in metastatic melanoma patients. The purpose of this study was to determine the efficacy of ipilimumab in advanced melanoma patients who showed progressive disease upon experimental dendritic cell (DC) vaccination.METHODS: Retrospective analysis...

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.

NPJ breast cancer

Joosten SEP, Wellenstein M, Koornstra R, van Rossum A, Sanders J, van der Noort V, Ferrandez MC, Harkes R, Mandjes IAM, Rosing H, Huitema A, Beijnen JH, Wesseling J, van Diest PJ, Horlings HM, Linn SC, Zwart W.
PMID: 34671036
NPJ Breast Cancer. 2021 Oct 20;7(1):138. doi: 10.1038/s41523-021-00344-3.

Window studies are gaining traction to assess (molecular) changes in short timeframes. Decreased tumor cell positivity for the proliferation marker Ki67 is often used as a proxy for treatment response. Immunohistochemistry (IHC)-based Ki67 on tissue from neo-adjuvant trials was...

EUS-guided radiofrequency ablation for a left adrenal oligometastasis of an esophageal adenocarcinoma.

VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy

Inderson A, Slingerland M, Farina Sarasqueta A, de Steur WO, Boonstra JJ.
PMID: 29916497
VideoGIE. 2018 Apr 12;3(5):159-161. doi: 10.1016/j.vgie.2018.03.001. eCollection 2018 May.

No abstract available.

Full-thickness scar resection following R1/Rx excised T1 colorectal cancers as alternative to completion surgery.

The American journal of gastroenterology

Gijsbers KM, Laclé MM, Elias SG, Backes Y, Bosman JH, van Berkel AM, Boersma F, Boonstra JJ, Bos PR, Dekker P, Didden PD, Geesing JMJ, Groen JN, Haasnoot KJC, Kessels K, van Lent AUG, van der Schee L, Schrauwen RWM, Schreuder RM, Schwartz MP, Seerden TJ, Spanier MBWM, Terhaar Sive Droste JS, Tuynman JB, de Vos Tot Nederveen Cappel WH, van Westreenen EHL, Wolfhagen FHJ, Vleggaar FP, Ter Borg F, Moons LMG.
PMID: 35029166
Am J Gastroenterol. 2021 Dec 31; doi: 10.14309/ajg.0000000000001621. Epub 2021 Dec 31.

INTRODUCTION: Local full-thickness resections of the scar (FTRS) following local excision of a T1 CRC with uncertain resection margins is proposed as alternative strategy to completion surgery (CS), provided that no local intramural residual cancer (LIRC) is found. However,...

Reply to E. Hindié.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Eggermont AMM, Blank CU, Mandala M, Long GV, Atkinson VG, Dalle S, Haydon AM, Meshcheryakov A, Khattak A, Carlino MS, Sandhu S, Larkin J, Puig S, Ascierto PA, Rutkowski P, Schadendorf D, Koornstra R, Hernandez-Aya L, Di Giacomo AM, van den Eertwegh AJM, Grob JJ, Gutzmer R, Jamal R, Lorigan PC, van Akkooi ACJ, Krepler C, Ibrahim N, Marreaud S, Kicinski M, Suciu S, Robert C.
PMID: 33492998
J Clin Oncol. 2021 Mar 10;39(8):944-946. doi: 10.1200/JCO.20.03463. Epub 2021 Jan 25.

No abstract available.

Hybrid endoscopic mucosal resection and full-thickness resection for large colonic polyps harboring a small focus of invasive cancer: a case series.

Endoscopy international open

Chua JS, Dang H, Zwager LW, Dekkers N, Hardwick JCH, Langers AMJ, van der Kraan J, Perk LE, Bastiaansen BAJ, Boonstra JJ.
PMID: 34790531
Endosc Int Open. 2021 Nov 12;9(11):E1686-E1691. doi: 10.1055/a-1529-1447. eCollection 2021 Nov.

Endoscopic treatment of large laterally spreading tumors (LSTs) with a focus of submucosally invasive colorectal cancer (T1 CRC) can be challenging. We evaluated outcomes of a hybrid resection technique using piecemeal endoscopic mucosal resection (pEMR) and endoscopic full-thickness resection...

Tumour-stroma ratio has poor prognostic value in nonpedunculated T1 colorectal cancer: A multicentre case-cohort study.

United European gastroenterology journal

Dang H, van Pelt GW, Haasnoot KJC, Backes Y, Elias SG, Seerden TCJ, Schwartz MP, Spanier BWM, de Vos Tot Nederveen Cappel WH, van Bergeijk JD, Kessels K, Geesing JMJ, Groen JN, Borg FT, Wolfhagen FHJ, Seldenrijk CA, Raicu MG, Milne AN, van Lent AUG, Brosens LAA, Johan A Offerhaus G, Siersema PD, Tollenaar RAEM, Hardwick JCH, Hawinkels LJAC, Moons LMG, Lacle MM, Mesker WE, Boonstra JJ.
PMID: 33566452
United European Gastroenterol J. 2021 Feb 10; doi: 10.1177/2050640620975324. Epub 2021 Feb 10.

BACKGROUND: Current risk stratification models for early invasive (T1) colorectal cancer are not able to discriminate accurately between prognostic favourable and unfavourable tumours, resulting in over-treatment of a large (>80%) proportion of T1 colorectal cancer patients. The tumour-stroma ratio...

Risk and Time Pattern of Recurrences After Local Endoscopic Resection of T1 Colorectal Cancer: A Meta-analysis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Dang H, Dekkers N, le Cessie S, van Hooft JE, van Leerdam ME, Oldenburg PP, Flothuis L, Schoones JW, Langers AMJ, Hardwick JCH, van der Kraan J, Boonstra JJ.
PMID: 33271339
Clin Gastroenterol Hepatol. 2020 Dec 01; doi: 10.1016/j.cgh.2020.11.032. Epub 2020 Dec 01.

BACKGROUND & AIMS: Growing numbers of patients with T1 CRC are being treated with local endoscopic resection only and as a result, the need for optimization of surveillance strategies for these patients also increases. We aimed to estimate the...

Is a colorectal neoplasm diagnosis a trigger to change dietary and other lifestyle habits for persons with Lynch syndrome? A prospective cohort study.

Familial cancer

Brouwer JGM, Snellen M, Bisseling TM, Koornstra JJ, Vasen HFA, Kampman E, van Duijnhoven FJB.
PMID: 32770331
Fam Cancer. 2021 Apr;20(2):125-135. doi: 10.1007/s10689-020-00201-5. Epub 2020 Aug 08.

A cancer diagnosis is suggested to be associated with changes in dietary and lifestyle habits. Whether this applies to persons with familial cancer, such as Lynch syndrome (LS) is unknown. We investigated whether a colorectal neoplasm (CRN) diagnosis in...

Showing 1 to 12 of 19 entries