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Showing 1 to 12 of 34 entries
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Immunomodulator Therapy in Inflammatory Bowel Disease.

Current treatment options in gastroenterology

Legnani PE, Kornbluth A.
PMID: 11469977
Curr Treat Options Gastroenterol. 2001 Jun;4(3):199-205. doi: 10.1007/s11938-001-0032-4.

6-Mercaptopurine and its prodrug counterpart, azathioprine, have proven efficacy in the induction and maintenance of remission, fistula closure, and steroid sparing in patients with Crohn's disease. Long-term follow-up has demonstrated the safety of the purine analogues, with no increased...

Small-Signal Performance and Modeling of sub-50nm nMOSFETs with f above 460-GHz.

Solid-state electronics

Dimitrov V, Heng J, Timp K, Dimauro O, Chan R, Hafez M, Feng J, Sorsch T, Mansfield W, Miner J, Kornblit A, Klemens F, Bower J, Cirelli R, Ferry EJ, Taylor A, Feng M, Timp G.
PMID: 20706596
Solid State Electron. 2008 Jun 01;52(6):899-908. doi: 10.1016/j.sse.2008.01.025.

We have fabricated and tested the performance of sub-50nm gate nMOSFETs to assess their suitability for mixed signal applications in the super high frequency (SHF) band, i.e. 3-30GHz. For a 30nm×40 μm×2 device, we found f(T) =465GHz at V(ds)=2V,...

Adalimumab: Another Treatment Option for Moderate-to-Severe UC.

Gastroenterology & hepatology

Kornbluth AA.
PMID: 23943670
Gastroenterol Hepatol (N Y). 2013 May;9(5):321.

No abstract available.

Clinical Evaluation of a COVID-19 Antibody Lateral Flow Assay using Point of Care Samples.

medRxiv : the preprint server for health sciences

Lee W, Straube S, Sincic R, Noble JA, Montoy JC, Kornblith AE, Prakash A, Wang R, Bainton R, Kurien P.
PMID: 33300003
medRxiv. 2020 Dec 04; doi: 10.1101/2020.12.02.20242750.

INTRODUCTION: The ongoing SARS-CoV-2 pandemic has spurred the development of numerous point of care (PoC) immunoassays. Assessments of performance of available kits are necessary to determine their clinical utility. Previous studies have mostly performed these assessments in a laboratory...

Newer Therapies for Inflammatory Bowel Disease.

Current treatment options in gastroenterology

Legnani P, Kornbluth A.
PMID: 15149578
Curr Treat Options Gastroenterol. 2004 Jun;7(3):161-167. doi: 10.1007/s11938-004-0037-x.

Recent controlled and uncontrolled trial data in inflammatory bowel disease have suggested several new avenues of possible therapies and refined our understanding of the uses and selectiveness of anti-tumor necrosis factor (TNF)-based therapies. Infliximab remains the only proven effective...

Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury.

Trauma surgery & acute care open

Howard BM, Kornblith LZ, Christie SA, Conroy AS, Nelson MF, Campion EM, Callcut RA, Calfee CS, Lamere BJ, Fadrosh DW, Lynch S, Cohen MJ.
PMID: 29766103
Trauma Surg Acute Care Open. 2017 Oct 23;2(1):e000108. doi: 10.1136/tsaco-2017-000108. eCollection 2017.

BACKGROUND: Recent studies have demonstrated the vital influence of commensal microbial communities on human health. The central role of the gut in the response to injury is well described; however, no prior studies have used culture-independent profiling techniques to...

Trauma Early Mortality Prediction Tool (TEMPT) for assessing 28-day mortality.

Trauma surgery & acute care open

Kunitake RC, Kornblith LZ, Cohen MJ, Callcut RA.
PMID: 29766125
Trauma Surg Acute Care Open. 2018 Jan 08;3(1):e000131. doi: 10.1136/tsaco-2017-000131. eCollection 2018.

BACKGROUND: Prior mortality prediction models have incorporated severity of anatomic injury quantified by Abbreviated Injury Severity Score (AIS). Using a prospective cohort, a new score independent of AIS was developed using clinical and laboratory markers present on emergency department...

Blunt trauma induced splenic blushes are not created equal.

World journal of emergency surgery : WJES

Burlew CC, Kornblith LZ, Moore EE, Johnson JL, Biffl WL.
PMID: 22462560
World J Emerg Surg. 2012 Mar 30;7:8. doi: 10.1186/1749-7922-7-8.

BACKGROUND: Currently, evidence of contrast extravasation on computed tomography (CT) scan is regarded as an indication for intervention in splenic injuries. In our experience, patients transferred from other institutions for angioembolization have often resolved the blush upon repeat imaging...

Cyclosporine versus infliximab for the treatment of severe ulcerative colitis.

Gastroenterology & hepatology

Kornbluth A.
PMID: 22298961
Gastroenterol Hepatol (N Y). 2011 Oct;7(10):677-9.

No abstract available.

Vedolizumab as a Treatment for Crohn's Disease and Ulcerative Colitis.

Gastroenterology & hepatology

Ha C, Kornbluth A.
PMID: 27524947
Gastroenterol Hepatol (N Y). 2014 Dec;10(12):793-800.

The management of Crohn's disease and ulcerative colitis has become increasingly complex. With the current utilization of immunosuppressive therapies earlier in the disease course for patients presenting with moderate to severe disease, there is a great need for additional...

Evaluating a Web-based Point-of-care Ultrasound Curriculum for the Diagnosis of Intussusception.

AEM education and training

Lin-Martore M, Olvera MP, Kornblith AE, Zapala M, Addo N, Lin M, Werner HC.
PMID: 34041433
AEM Educ Train. 2020 Sep 23;5(3):e10526. doi: 10.1002/aet2.10526. eCollection 2021 Jul.

OBJECTIVES: Intussusception is a pediatric medical emergency that can be difficult to diagnose. Radiology-performed ultrasound is the diagnostic study of choice but may lead to delays due to lack of availability. Point-of-care ultrasound for intussusception (POCUS-I) studies have shown...

Challenging Traditional Paradigms in Posttraumatic Pulmonary Thromboembolism.

JAMA surgery

Knudson MM, Moore EE, Kornblith LZ, Shui AM, Brakenridge S, Bruns BR, Cipolle MD, Costantini TW, Crookes BA, Haut ER, Kerwin AJ, Kiraly LN, Knowlton LM, Martin MJ, McNutt MK, Milia DJ, Mohr A, Nirula R, Rogers FB, Scalea TM, Sixta SL, Spain DA, Wade CE, Velmahos GC.
PMID: 34910098
JAMA Surg. 2021 Dec 15;e216356. doi: 10.1001/jamasurg.2021.6356. Epub 2021 Dec 15.

IMPORTANCE: Pulmonary clots are seen frequently on chest computed tomography performed after trauma, but recent studies suggest that pulmonary thrombosis (PT) and pulmonary embolism (PE) after trauma are independent clinical events.OBJECTIVE: To assess whether posttraumatic PT represents a distinct...

Showing 1 to 12 of 34 entries