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PARP1 Inhibitors: antitumor drug design.

Acta naturae

Malyuchenko NV, Kotova EY, Kulaeva OI, Kirpichnikov MP, Studitskiy VM.
PMID: 26483957
Acta Naturae. 2015 Jul-Sep;7(3):27-37.

The poly (ADP-ribose) polymerase 1 (PARP1) enzyme is one of the promising molecular targets for the discovery of antitumor drugs. PARP1 is a common nuclear protein (1-2 million molecules per cell) serving as a "sensor" for DNA strand breaks....

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Malyuchenko NV, Kotova EY, Kulaeva OI, et al. PARP1 Inhibitors: antitumor drug design. Acta Naturae. 2015;7(3):27-37
Malyuchenko, N. V., Kotova, E. Y., Kulaeva, O. I., Kirpichnikov, M. P., & Studitskiy, V. M. (2015). PARP1 Inhibitors: antitumor drug design. Acta naturae, 7(3), 27-37.
Malyuchenko, N V, et al. "PARP1 Inhibitors: antitumor drug design." Acta naturae vol. 7,3 (2015): 27-37.
Malyuchenko NV, Kotova EY, Kulaeva OI, Kirpichnikov MP, Studitskiy VM. PARP1 Inhibitors: antitumor drug design. Acta Naturae. 2015 Jul-Sep;7(3):27-37. PMID: 26483957; PMCID: PMC4610162.
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Poly[μ-aqua-diaquabis-[μ-2-cyano-2-(oxidoimino)-acetato]-copper(II)dipotassium].

Acta crystallographica. Section E, Structure reports online

Golenya IA, Izotova YA, Usenko NI, Kalibabchuk VA, Kotova NV.
PMID: 23125617
Acta Crystallogr Sect E Struct Rep Online. 2012 Oct 01;68:m1303-4. doi: 10.1107/S1600536812036641. Epub 2012 Sep 26.

In the title compound, [CuK(2)(C(3)N(2)O(3))(2)(H(2)O)(3)](n), the Cu(2+) atom is in a distorted square-pyramidal coordination geometry. Two N atoms belonging to the oxime groups and two O atoms belonging to the carboxyl-ate groups of two trans-disposed doubly deprotonated residues of...

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Golenya IA, Izotova YA, Usenko NI, et al. Poly[μ-aqua-diaquabis-[μ-2-cyano-2-(oxidoimino)-acetato]-copper(II)dipotassium]. Acta Crystallogr Sect E Struct Rep Online. 2012;68:m1303-4doi: 10.1107/S1600536812036641.
Golenya, I. A., Izotova, Y. A., Usenko, N. I., Kalibabchuk, V. A., & Kotova, N. V. (2012). Poly[μ-aqua-diaquabis-[μ-2-cyano-2-(oxidoimino)-acetato]-copper(II)dipotassium]. Acta crystallographica. Section E, Structure reports online, 68m1303-4. https://doi.org/10.1107/S1600536812036641
Golenya, Irina A, et al. "Poly[μ-aqua-diaquabis-[μ-2-cyano-2-(oxidoimino)-acetato]-copper(II)dipotassium]." Acta crystallographica. Section E, Structure reports online vol. 68 (2012): m1303-4. doi: https://doi.org/10.1107/S1600536812036641
Golenya IA, Izotova YA, Usenko NI, Kalibabchuk VA, Kotova NV. Poly[μ-aqua-diaquabis-[μ-2-cyano-2-(oxidoimino)-acetato]-copper(II)dipotassium]. Acta Crystallogr Sect E Struct Rep Online. 2012 Oct 01;68:m1303-4. doi: 10.1107/S1600536812036641. Epub 2012 Sep 26. PMID: 23125617; PMCID: PMC3470173.
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Studies on the interactions of 5-R-3-(2-pyridyl)-1,2,4-triazines with arynes: inverse demand aza-Diels-Alder reaction versus aryne-mediated domino process.

Organic & biomolecular chemistry

Kopchuk DS, Nikonov IL, Khasanov AF, Giri K, Santra S, Kovalev IS, Nosova EV, Gundala S, Venkatapuram P, Zyryanov GV, Majee A, Chupakhin ON.
PMID: 29718037
Org Biomol Chem. 2018 Jul 18;16(28):5119-5135. doi: 10.1039/c8ob00847g.

The interactions between substituted 5-R-3-(pyridyl-2)-1,2,4-triazines with in situ generated substituted aryne intermediates have been studied. The reaction afforded either inverse demand (ID) aza-Diels-Alder products or 1,2,4-triazine ring rearrangement (domino) products as major ones depending on the nature of both...

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Kopchuk DS, Nikonov IL, Khasanov AF, et al. Studies on the interactions of 5-R-3-(2-pyridyl)-1,2,4-triazines with arynes: inverse demand aza-Diels-Alder reaction versus aryne-mediated domino process. Org Biomol Chem. 2018;16(28):5119-5135doi: 10.1039/c8ob00847g.
Kopchuk, D. S., Nikonov, I. L., Khasanov, A. F., Giri, K., Santra, S., Kovalev, I. S., Nosova, E. V., Gundala, S., Venkatapuram, P., Zyryanov, G. V., Majee, A., & Chupakhin, O. N. (2018). Studies on the interactions of 5-R-3-(2-pyridyl)-1,2,4-triazines with arynes: inverse demand aza-Diels-Alder reaction versus aryne-mediated domino process. Organic & biomolecular chemistry, 16(28), 5119-5135. https://doi.org/10.1039/c8ob00847g
Kopchuk, Dmitry S, et al. "Studies on the interactions of 5-R-3-(2-pyridyl)-1,2,4-triazines with arynes: inverse demand aza-Diels-Alder reaction versus aryne-mediated domino process." Organic & biomolecular chemistry vol. 16,28 (2018): 5119-5135. doi: https://doi.org/10.1039/c8ob00847g
Kopchuk DS, Nikonov IL, Khasanov AF, Giri K, Santra S, Kovalev IS, Nosova EV, Gundala S, Venkatapuram P, Zyryanov GV, Majee A, Chupakhin ON. Studies on the interactions of 5-R-3-(2-pyridyl)-1,2,4-triazines with arynes: inverse demand aza-Diels-Alder reaction versus aryne-mediated domino process. Org Biomol Chem. 2018 Jul 18;16(28):5119-5135. doi: 10.1039/c8ob00847g. PMID: 29718037.
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Crystal structure and migration paths of alkaline ions in NaVPO.

Physical chemistry chemical physics : PCCP

Semykina DO, Yakovlev IV, Lapina OB, Kabanov AA, Kosova NV.
PMID: 32638762
Phys Chem Chem Phys. 2020 Jul 22;22(28):15876-15884. doi: 10.1039/d0cp02204g.

A sample with a nominal composition 'NaVPO4F' is prepared by mechanochemically assisted solid-state synthesis using quenching. A detailed study of its crystal and local structure is conducted by means of XRD and FTIR and solid-state 31P NMR spectroscopies in...

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Semykina DO, Yakovlev IV, Lapina OB, et al. Crystal structure and migration paths of alkaline ions in NaVPO. Phys Chem Chem Phys. 2020;22(28):15876-15884doi: 10.1039/d0cp02204g.
Semykina, D. O., Yakovlev, I. V., Lapina, O. B., Kabanov, A. A., & Kosova, N. V. (2020). Crystal structure and migration paths of alkaline ions in NaVPO. Physical chemistry chemical physics : PCCP, 22(28), 15876-15884. https://doi.org/10.1039/d0cp02204g
Semykina, D O, et al. "Crystal structure and migration paths of alkaline ions in NaVPO." Physical chemistry chemical physics : PCCP vol. 22,28 (2020): 15876-15884. doi: https://doi.org/10.1039/d0cp02204g
Semykina DO, Yakovlev IV, Lapina OB, Kabanov AA, Kosova NV. Crystal structure and migration paths of alkaline ions in NaVPO. Phys Chem Chem Phys. 2020 Jul 22;22(28):15876-15884. doi: 10.1039/d0cp02204g. PMID: 32638762.
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Genomic Variants and Multilevel Regulation of .

Journal of cardiovascular development and disease

Rozhkova AV, Dmitrieva VG, Nosova EV, Dergunov AD, Limborska SA, Dergunova LV.
PMID: 34940525
J Cardiovasc Dev Dis. 2021 Dec 02;8(12). doi: 10.3390/jcdd8120170.

Atheroprotective properties of human plasma high-density lipoproteins (HDLs) are determined by their involvement in reverse cholesterol transport (RCT) from the macrophage to the liver.

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Rozhkova AV, Dmitrieva VG, Nosova EV, et al. Genomic Variants and Multilevel Regulation of . J Cardiovasc Dev Dis. 2021;8(12)doi: 10.3390/jcdd8120170.
Rozhkova, A. V., Dmitrieva, V. G., Nosova, E. V., Dergunov, A. D., Limborska, S. A., & Dergunova, L. V. (2021). Genomic Variants and Multilevel Regulation of . Journal of cardiovascular development and disease, 8(12), . https://doi.org/10.3390/jcdd8120170
Rozhkova, Alexandra V, et al. "Genomic Variants and Multilevel Regulation of ." Journal of cardiovascular development and disease vol. 8,12 (2021). doi: https://doi.org/10.3390/jcdd8120170
Rozhkova AV, Dmitrieva VG, Nosova EV, Dergunov AD, Limborska SA, Dergunova LV. Genomic Variants and Multilevel Regulation of . J Cardiovasc Dev Dis. 2021 Dec 02;8(12). doi: 10.3390/jcdd8120170. PMID: 34940525.
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Peptide-induced membrane elastic deformations decelerate gramicidin dimer-monomer equilibration.

Biophysical journal

Kondrashov OV, Rokitskaya TI, Batishchev OV, Kotova EA, Antonenko YN, Akimov SA.
PMID: 34715080
Biophys J. 2021 Dec 07;120(23):5309-5321. doi: 10.1016/j.bpj.2021.10.030. Epub 2021 Oct 27.

Gramicidin A (gA) is a hydrophobic pentadecapeptide readily incorporating into a planar bilayer lipid membrane (BLM), thereby inducing a large macroscopic current across the BLM. This current results from ion-channel formation due to head-to-head transbilayer dimerization of gA monomers...

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Kondrashov OV, Rokitskaya TI, Batishchev OV, et al. Peptide-induced membrane elastic deformations decelerate gramicidin dimer-monomer equilibration. Biophys J. 2021;120(23):5309-5321doi: 10.1016/j.bpj.2021.10.030.
Kondrashov, O. V., Rokitskaya, T. I., Batishchev, O. V., Kotova, E. A., Antonenko, Y. N., & Akimov, S. A. (2021). Peptide-induced membrane elastic deformations decelerate gramicidin dimer-monomer equilibration. Biophysical journal, 120(23), 5309-5321. https://doi.org/10.1016/j.bpj.2021.10.030
Kondrashov, Oleg V, et al. "Peptide-induced membrane elastic deformations decelerate gramicidin dimer-monomer equilibration." Biophysical journal vol. 120,23 (2021): 5309-5321. doi: https://doi.org/10.1016/j.bpj.2021.10.030
Kondrashov OV, Rokitskaya TI, Batishchev OV, Kotova EA, Antonenko YN, Akimov SA. Peptide-induced membrane elastic deformations decelerate gramicidin dimer-monomer equilibration. Biophys J. 2021 Dec 07;120(23):5309-5321. doi: 10.1016/j.bpj.2021.10.030. Epub 2021 Oct 27. PMID: 34715080.
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New Solvent-Free Melting-Assisted Preparation of Energetic Compound of Nickel with Imidazole for Combustion Synthesis of Ni-Based Materials.

Nanomaterials (Basel, Switzerland)

Komova OV, Mukha SA, Ozerova AM, Bulavchenko OA, Pochtar AA, Ishchenko AV, Odegova GV, Suknev AP, Netskina OV.
PMID: 34947681
Nanomaterials (Basel). 2021 Dec 08;11(12). doi: 10.3390/nano11123332.

In this work two approaches to the synthesis of energetic complex compound Ni(Im)

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Komova OV, Mukha SA, Ozerova AM, et al. New Solvent-Free Melting-Assisted Preparation of Energetic Compound of Nickel with Imidazole for Combustion Synthesis of Ni-Based Materials. Nanomaterials (Basel). 2021;11(12)doi: 10.3390/nano11123332.
Komova, O. V., Mukha, S. A., Ozerova, A. M., Bulavchenko, O. A., Pochtar, A. A., Ishchenko, A. V., Odegova, G. V., Suknev, A. P., & Netskina, O. V. (2021). New Solvent-Free Melting-Assisted Preparation of Energetic Compound of Nickel with Imidazole for Combustion Synthesis of Ni-Based Materials. Nanomaterials (Basel, Switzerland), 11(12), . https://doi.org/10.3390/nano11123332
Komova, Oksana V, et al. "New Solvent-Free Melting-Assisted Preparation of Energetic Compound of Nickel with Imidazole for Combustion Synthesis of Ni-Based Materials." Nanomaterials (Basel, Switzerland) vol. 11,12 (2021). doi: https://doi.org/10.3390/nano11123332
Komova OV, Mukha SA, Ozerova AM, Bulavchenko OA, Pochtar AA, Ishchenko AV, Odegova GV, Suknev AP, Netskina OV. New Solvent-Free Melting-Assisted Preparation of Energetic Compound of Nickel with Imidazole for Combustion Synthesis of Ni-Based Materials. Nanomaterials (Basel). 2021 Dec 08;11(12). doi: 10.3390/nano11123332. PMID: 34947681.
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Leveraging technology for the treatment of type 1 diabetes in pregnancy: A review of past, current, and future therapeutic tools.

Journal of diabetes

Nosova EV, O'Malley G, Dassau E, Levy CJ.
PMID: 32125763
J Diabetes. 2020 Oct;12(10):714-732. doi: 10.1111/1753-0407.13030. Epub 2020 Mar 20.

The significant risks associated with pregnancies complicated by type 1 diabetes (T1D) were first recognized in the medical literature in the mid-twentieth century. Stringent glycemic control with hemoglobin A1c (HbA1c) values ideally less than 6% has been shown to...

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Nosova EV, O'Malley G, Dassau E, et al. Leveraging technology for the treatment of type 1 diabetes in pregnancy: A review of past, current, and future therapeutic tools. J Diabetes. 2020;12(10):714-732doi: 10.1111/1753-0407.13030.
Nosova, E. V., O'Malley, G., Dassau, E., & Levy, C. J. (2020). Leveraging technology for the treatment of type 1 diabetes in pregnancy: A review of past, current, and future therapeutic tools. Journal of diabetes, 12(10), 714-732. https://doi.org/10.1111/1753-0407.13030
Nosova, Emily V, et al. "Leveraging technology for the treatment of type 1 diabetes in pregnancy: A review of past, current, and future therapeutic tools." Journal of diabetes vol. 12,10 (2020): 714-732. doi: https://doi.org/10.1111/1753-0407.13030
Nosova EV, O'Malley G, Dassau E, Levy CJ. Leveraging technology for the treatment of type 1 diabetes in pregnancy: A review of past, current, and future therapeutic tools. J Diabetes. 2020 Oct;12(10):714-732. doi: 10.1111/1753-0407.13030. Epub 2020 Mar 20. PMID: 32125763.
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The Formation of Perovskite during the Combustion of an Energy-Rich Glycine-Nitrate Precursor.

Materials (Basel, Switzerland)

Komova OV, Mukha SA, Ozerova AM, Odegova GV, Simagina VI, Bulavchenko OA, Ishchenko AV, Netskina OV.
PMID: 33187295
Materials (Basel). 2020 Nov 11;13(22). doi: 10.3390/ma13225091.

The effect of different regimes of combustion of glycine-nitrate precursors on the formation of perovskite phases (LaMnO

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Komova OV, Mukha SA, Ozerova AM, et al. The Formation of Perovskite during the Combustion of an Energy-Rich Glycine-Nitrate Precursor. Materials (Basel). 2020;13(22)doi: 10.3390/ma13225091.
Komova, O. V., Mukha, S. A., Ozerova, A. M., Odegova, G. V., Simagina, V. I., Bulavchenko, O. A., Ishchenko, A. V., & Netskina, O. V. (2020). The Formation of Perovskite during the Combustion of an Energy-Rich Glycine-Nitrate Precursor. Materials (Basel, Switzerland), 13(22), . https://doi.org/10.3390/ma13225091
Komova, Oksana V, et al. "The Formation of Perovskite during the Combustion of an Energy-Rich Glycine-Nitrate Precursor." Materials (Basel, Switzerland) vol. 13,22 (2020). doi: https://doi.org/10.3390/ma13225091
Komova OV, Mukha SA, Ozerova AM, Odegova GV, Simagina VI, Bulavchenko OA, Ishchenko AV, Netskina OV. The Formation of Perovskite during the Combustion of an Energy-Rich Glycine-Nitrate Precursor. Materials (Basel). 2020 Nov 11;13(22). doi: 10.3390/ma13225091. PMID: 33187295; PMCID: PMC7696830.
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Identification of Stem Rust Resistance Genes in the Winter Wheat Collection from Southern Russia.

Plants (Basel, Switzerland)

Alabushev AV, Vozhzhova NN, Kupreyshvili NT, Shishkin NV, Marchenko DM, Ionova EV.
PMID: 31801237
Plants (Basel). 2019 Nov 30;8(12). doi: 10.3390/plants8120559.

The high yield potential of winter wheats cannot be realized due to disease pressure under field conditions. One of the most harmful of such diseases is stem rust, hence the constant search for sources of resistance and the development...

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Alabushev AV, Vozhzhova NN, Kupreyshvili NT, et al. Identification of Stem Rust Resistance Genes in the Winter Wheat Collection from Southern Russia. Plants (Basel). 2019;8(12)doi: 10.3390/plants8120559.
Alabushev, A. V., Vozhzhova, N. N., Kupreyshvili, N. T., Shishkin, N. V., Marchenko, D. M., & Ionova, E. V. (2019). Identification of Stem Rust Resistance Genes in the Winter Wheat Collection from Southern Russia. Plants (Basel, Switzerland), 8(12), . https://doi.org/10.3390/plants8120559
Alabushev, Andrey V, et al. "Identification of Stem Rust Resistance Genes in the Winter Wheat Collection from Southern Russia." Plants (Basel, Switzerland) vol. 8,12 (2019). doi: https://doi.org/10.3390/plants8120559
Alabushev AV, Vozhzhova NN, Kupreyshvili NT, Shishkin NV, Marchenko DM, Ionova EV. Identification of Stem Rust Resistance Genes in the Winter Wheat Collection from Southern Russia. Plants (Basel). 2019 Nov 30;8(12). doi: 10.3390/plants8120559. PMID: 31801237; PMCID: PMC6963428.
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A Randomized, Double-Blind, Placebo-Controlled Trial of Ibuprofen Lysinate in Comparison to Ibuprofen Acid for Acute Postoperative Dental Pain.

Pain and therapy

Kyselovič J, Koscova E, Lampert A, Weiser T.
PMID: 31912434
Pain Ther. 2020 Jun;9(1):249-259. doi: 10.1007/s40122-019-00148-1. Epub 2020 Jan 07.

INTRODUCTION: Ibuprofen acid is poorly soluble in the stomach, thus reaching maximum plasma levels at approximately 90 min post-dose. Ibuprofen lysinate has been developed to accelerate absorption of ibuprofen to shorten the time to analgesic efficacy. This study compared...

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Kyselovič J, Koscova E, Lampert A, et al. A Randomized, Double-Blind, Placebo-Controlled Trial of Ibuprofen Lysinate in Comparison to Ibuprofen Acid for Acute Postoperative Dental Pain. Pain Ther. 2020;9(1):249-259doi: 10.1007/s40122-019-00148-1.
Kyselovič, J., Koscova, E., Lampert, A., & Weiser, T. (2020). A Randomized, Double-Blind, Placebo-Controlled Trial of Ibuprofen Lysinate in Comparison to Ibuprofen Acid for Acute Postoperative Dental Pain. Pain and therapy, 9(1), 249-259. https://doi.org/10.1007/s40122-019-00148-1
Kyselovič, Ján, et al. "A Randomized, Double-Blind, Placebo-Controlled Trial of Ibuprofen Lysinate in Comparison to Ibuprofen Acid for Acute Postoperative Dental Pain." Pain and therapy vol. 9,1 (2020): 249-259. doi: https://doi.org/10.1007/s40122-019-00148-1
Kyselovič J, Koscova E, Lampert A, Weiser T. A Randomized, Double-Blind, Placebo-Controlled Trial of Ibuprofen Lysinate in Comparison to Ibuprofen Acid for Acute Postoperative Dental Pain. Pain Ther. 2020 Jun;9(1):249-259. doi: 10.1007/s40122-019-00148-1. Epub 2020 Jan 07. PMID: 31912434; PMCID: PMC7203382.
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Genomic Variants and Multilevel Regulation of .

Journal of cardiovascular development and disease

Rozhkova AV, Dmitrieva VG, Nosova EV, Dergunov AD, Limborska SA, Dergunova LV.
PMID: 34940525
J Cardiovasc Dev Dis. 2021 Dec 02;8(12). doi: 10.3390/jcdd8120170.

Atheroprotective properties of human plasma high-density lipoproteins (HDLs) are determined by their involvement in reverse cholesterol transport (RCT) from the macrophage to the liver.

Cite
Rozhkova AV, Dmitrieva VG, Nosova EV, et al. Genomic Variants and Multilevel Regulation of . J Cardiovasc Dev Dis. 2021;8(12)doi: 10.3390/jcdd8120170.
Rozhkova, A. V., Dmitrieva, V. G., Nosova, E. V., Dergunov, A. D., Limborska, S. A., & Dergunova, L. V. (2021). Genomic Variants and Multilevel Regulation of . Journal of cardiovascular development and disease, 8(12), . https://doi.org/10.3390/jcdd8120170
Rozhkova, Alexandra V, et al. "Genomic Variants and Multilevel Regulation of ." Journal of cardiovascular development and disease vol. 8,12 (2021). doi: https://doi.org/10.3390/jcdd8120170
Rozhkova AV, Dmitrieva VG, Nosova EV, Dergunov AD, Limborska SA, Dergunova LV. Genomic Variants and Multilevel Regulation of . J Cardiovasc Dev Dis. 2021 Dec 02;8(12). doi: 10.3390/jcdd8120170. PMID: 34940525.
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Showing 1 to 12 of 69 entries