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Showing 1 to 12 of 18 entries
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H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma.

Current molecular pharmacology

Bosgana P, Nikou S, Dimitrakopoulos FI, Logotheti S, Tzelepi V, Kalophonos C, Bravou V, Kourea E, Sampsonas F, Zolota V.
PMID: 32867667
Curr Mol Pharmacol. 2020 Aug 31; doi: 10.2174/1874467213999200831130739. Epub 2020 Aug 31.

BACKGROUND: Genetic events cannot account for the complexity of human carcinogenesis alone. Mutations of epigenetic regulators and aberrations of their expression patterns have been detected in various human malignancies. Methylation of histone H3 at lysine 4 (H3K4me), is an...

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Bosgana P, Nikou S, Dimitrakopoulos FI, et al. H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma. Curr Mol Pharmacol. 2020;doi: 10.2174/1874467213999200831130739.
Bosgana, P., Nikou, S., Dimitrakopoulos, F. I., Logotheti, S., Tzelepi, V., Kalophonos, C., Bravou, V., Kourea, E., Sampsonas, F., & Zolota, V. (2020). H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma. Current molecular pharmacology, . https://doi.org/10.2174/1874467213999200831130739
Bosgana, Pinelopi, et al. "H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma." Current molecular pharmacology vol. (2020). doi: https://doi.org/10.2174/1874467213999200831130739
Bosgana P, Nikou S, Dimitrakopoulos FI, Logotheti S, Tzelepi V, Kalophonos C, Bravou V, Kourea E, Sampsonas F, Zolota V. H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma. Curr Mol Pharmacol. 2020 Aug 31; doi: 10.2174/1874467213999200831130739. Epub 2020 Aug 31. PMID: 32867667.
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Prevalence of Obesity Among Male Adolescents in Arar Saudi Arabia: Future Risk of Cardiovascular Disease.

Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

Alenazi SA, Koura HM, Zaki SM, Mohamed AH.
PMID: 26170543
Indian J Community Med. 2015 Jul-Sep;40(3):182-7. doi: 10.4103/0970-0218.158864.

BACKGROUND: Obesity in adolescence is crucial as it represents an important stage in human life. Dietary habits are greatly associated with lifestyle. Many reports suggested direct relationship between adolescent fatness and increased risk of cardiovascular diseases (CVD) which will...

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Alenazi SA, Koura HM, Zaki SM, et al. Prevalence of Obesity Among Male Adolescents in Arar Saudi Arabia: Future Risk of Cardiovascular Disease. Indian J Community Med. 2015;40(3):182-7doi: 10.4103/0970-0218.158864.
Alenazi, S. A., Koura, H. M., Zaki, S. M., & Mohamed, A. H. (2015). Prevalence of Obesity Among Male Adolescents in Arar Saudi Arabia: Future Risk of Cardiovascular Disease. Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine, 40(3), 182-7. https://doi.org/10.4103/0970-0218.158864
Alenazi, Shehab A, et al. "Prevalence of Obesity Among Male Adolescents in Arar Saudi Arabia: Future Risk of Cardiovascular Disease." Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine vol. 40,3 (2015): 182-7. doi: https://doi.org/10.4103/0970-0218.158864
Alenazi SA, Koura HM, Zaki SM, Mohamed AH. Prevalence of Obesity Among Male Adolescents in Arar Saudi Arabia: Future Risk of Cardiovascular Disease. Indian J Community Med. 2015 Jul-Sep;40(3):182-7. doi: 10.4103/0970-0218.158864. PMID: 26170543; PMCID: PMC4478660.
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Association of antimullerian hormone with the size of the appendix testis, the androgen and estrogen receptors and their expression in the appendix testis, in congenital cryptorchidism.

Journal of pediatric endocrinology & metabolism : JPEM

Sinopidis X, Kostopoulou E, Rojas-Gil AP, Panagidis A, Kourea E, Skiadopoulos S, Georgiou G, Spiliotis BE.
PMID: 34265880
J Pediatr Endocrinol Metab. 2021 Jul 16;34(10):1247-1255. doi: 10.1515/jpem-2021-0240. Print 2021 Oct 26.

OBJECTIVES: Antimullerian hormone (AMH) causes regression of the mullerian ducts in the male fetus. The appendix testis (AT) is a vestigial remnant of mullerian duct origin, containing both androgen (AR) and estrogen (ER) receptors. The role of both AMH...

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Sinopidis X, Kostopoulou E, Rojas-Gil AP, et al. Association of antimullerian hormone with the size of the appendix testis, the androgen and estrogen receptors and their expression in the appendix testis, in congenital cryptorchidism. J Pediatr Endocrinol Metab. 2021;34(10):1247-1255doi: 10.1515/jpem-2021-0240.
Sinopidis, X., Kostopoulou, E., Rojas-Gil, A. P., Panagidis, A., Kourea, E., Skiadopoulos, S., Georgiou, G., & Spiliotis, B. E. (2021). Association of antimullerian hormone with the size of the appendix testis, the androgen and estrogen receptors and their expression in the appendix testis, in congenital cryptorchidism. Journal of pediatric endocrinology & metabolism : JPEM, 34(10), 1247-1255. https://doi.org/10.1515/jpem-2021-0240
Sinopidis, Xenophon, et al. "Association of antimullerian hormone with the size of the appendix testis, the androgen and estrogen receptors and their expression in the appendix testis, in congenital cryptorchidism." Journal of pediatric endocrinology & metabolism : JPEM vol. 34,10 (2021): 1247-1255. doi: https://doi.org/10.1515/jpem-2021-0240
Sinopidis X, Kostopoulou E, Rojas-Gil AP, Panagidis A, Kourea E, Skiadopoulos S, Georgiou G, Spiliotis BE. Association of antimullerian hormone with the size of the appendix testis, the androgen and estrogen receptors and their expression in the appendix testis, in congenital cryptorchidism. J Pediatr Endocrinol Metab. 2021 Jul 16;34(10):1247-1255. doi: 10.1515/jpem-2021-0240. Print 2021 Oct 26. PMID: 34265880.
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Epigenetic Alterations in Triple-Negative Breast Cancer-The Critical Role of Extracellular Matrix.

Cancers

Zolota V, Tzelepi V, Piperigkou Z, Kourea H, Papakonstantinou E, Argentou ΜI, Karamanos NK.
PMID: 33572395
Cancers (Basel). 2021 Feb 09;13(4). doi: 10.3390/cancers13040713.

Triple-negative breast cancer (TNBC) is an aggressive subgroup of breast cancer characterized by genomic complexity and therapeutic options limited to only standard chemotherapy. Although it has been suggested that stratifying TNBC patients by pathway-specific molecular alterations may predict benefit...

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Zolota V, Tzelepi V, Piperigkou Z, et al. Epigenetic Alterations in Triple-Negative Breast Cancer-The Critical Role of Extracellular Matrix. Cancers (Basel). 2021;13(4)doi: 10.3390/cancers13040713.
Zolota, V., Tzelepi, V., Piperigkou, Z., Kourea, H., Papakonstantinou, E., Argentou, �. �. I., & Karamanos, N. K. (2021). Epigenetic Alterations in Triple-Negative Breast Cancer-The Critical Role of Extracellular Matrix. Cancers, 13(4), . https://doi.org/10.3390/cancers13040713
Zolota, Vasiliki, et al. "Epigenetic Alterations in Triple-Negative Breast Cancer-The Critical Role of Extracellular Matrix." Cancers vol. 13,4 (2021). doi: https://doi.org/10.3390/cancers13040713
Zolota V, Tzelepi V, Piperigkou Z, Kourea H, Papakonstantinou E, Argentou ΜI, Karamanos NK. Epigenetic Alterations in Triple-Negative Breast Cancer-The Critical Role of Extracellular Matrix. Cancers (Basel). 2021 Feb 09;13(4). doi: 10.3390/cancers13040713. PMID: 33572395; PMCID: PMC7916242.
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A Case of Canine Polyglandular Deficiency Syndrome with Diabetes Mellitus and Hypoadrenocorticism.

Veterinary sciences

Furukawa S, Meguri N, Koura K, Koura H, Matsuda A.
PMID: 33800028
Vet Sci. 2021 Mar 07;8(3). doi: 10.3390/vetsci8030043.

This report describes the first clinical case, to our knowledge, of a dog with polyglandular deficiency syndrome with diabetes mellitus and hypoadrenocorticism. A six-year-old female Cavalier King Charles Spaniel presented with a history of lethargy and appetite loss. The...

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Furukawa S, Meguri N, Koura K, et al. A Case of Canine Polyglandular Deficiency Syndrome with Diabetes Mellitus and Hypoadrenocorticism. Vet Sci. 2021;8(3)doi: 10.3390/vetsci8030043.
Furukawa, S., Meguri, N., Koura, K., Koura, H., & Matsuda, A. (2021). A Case of Canine Polyglandular Deficiency Syndrome with Diabetes Mellitus and Hypoadrenocorticism. Veterinary sciences, 8(3), . https://doi.org/10.3390/vetsci8030043
Furukawa, Sho, et al. "A Case of Canine Polyglandular Deficiency Syndrome with Diabetes Mellitus and Hypoadrenocorticism." Veterinary sciences vol. 8,3 (2021). doi: https://doi.org/10.3390/vetsci8030043
Furukawa S, Meguri N, Koura K, Koura H, Matsuda A. A Case of Canine Polyglandular Deficiency Syndrome with Diabetes Mellitus and Hypoadrenocorticism. Vet Sci. 2021 Mar 07;8(3). doi: 10.3390/vetsci8030043. PMID: 33800028; PMCID: PMC8000634.
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Congenital midline cervical cleft: diagnosis, pathologic findings, and early stage treatment.

Case reports in pediatrics

Sinopidis X, Kourea HP, Panagidis A, Alexopoulos V, Tzifas S, Dimitriou G, Georgiou G.
PMID: 23094176
Case Rep Pediatr. 2012;2012:951040. doi: 10.1155/2012/951040. Epub 2012 Oct 09.

Congenital midline cervical cleft is a very uncommon malformation of the anterior neck, with less than 100 cases reported in medical literature. Herein we present a case of a female neonate with this anomaly. A detailed description of the...

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Sinopidis X, Kourea HP, Panagidis A, et al. Congenital midline cervical cleft: diagnosis, pathologic findings, and early stage treatment. Case Rep Pediatr. 2012;2012:951040doi: 10.1155/2012/951040.
Sinopidis, X., Kourea, H. P., Panagidis, A., Alexopoulos, V., Tzifas, S., Dimitriou, G., & Georgiou, G. (2012). Congenital midline cervical cleft: diagnosis, pathologic findings, and early stage treatment. Case reports in pediatrics, 2012951040. https://doi.org/10.1155/2012/951040
Sinopidis, Xenophon, et al. "Congenital midline cervical cleft: diagnosis, pathologic findings, and early stage treatment." Case reports in pediatrics vol. 2012 (2012): 951040. doi: https://doi.org/10.1155/2012/951040
Sinopidis X, Kourea HP, Panagidis A, Alexopoulos V, Tzifas S, Dimitriou G, Georgiou G. Congenital midline cervical cleft: diagnosis, pathologic findings, and early stage treatment. Case Rep Pediatr. 2012;2012:951040. doi: 10.1155/2012/951040. Epub 2012 Oct 09. PMID: 23094176; PMCID: PMC3474213.
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Lymphocyte Activation Markers in Pediatric Kidney Transplant Recipients.

International journal of biomedical science : IJBS

Fadel FI, Elghoroury EA, Elshamaa MF, Bazaraa HM, Salah DM, Kassem NM, Ibrahim MH, El-Saaid GS, Nasr SA, Koura HM.
PMID: 26508906
Int J Biomed Sci. 2015 Sep;11(3):121-30.

BACKGROUND AND OBJECTIVES: The role of CD4+CD25+ T regulatory cells (Tregs) in immune tolerance in experimental transplantation is very important but the clinical significance of circulating Tregs in the peripheral blood is undetermined. We evaluated the association between the...

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Fadel FI, Elghoroury EA, Elshamaa MF, et al. Lymphocyte Activation Markers in Pediatric Kidney Transplant Recipients. Int J Biomed Sci. 2015;11(3):121-30
Fadel, F. I., Elghoroury, E. A., Elshamaa, M. F., Bazaraa, H. M., Salah, D. M., Kassem, N. M., Ibrahim, M. H., El-Saaid, G. S., Nasr, S. A., & Koura, H. M. (2015). Lymphocyte Activation Markers in Pediatric Kidney Transplant Recipients. International journal of biomedical science : IJBS, 11(3), 121-30.
Fadel, Fatina I, et al. "Lymphocyte Activation Markers in Pediatric Kidney Transplant Recipients." International journal of biomedical science : IJBS vol. 11,3 (2015): 121-30.
Fadel FI, Elghoroury EA, Elshamaa MF, Bazaraa HM, Salah DM, Kassem NM, Ibrahim MH, El-Saaid GS, Nasr SA, Koura HM. Lymphocyte Activation Markers in Pediatric Kidney Transplant Recipients. Int J Biomed Sci. 2015 Sep;11(3):121-30. PMID: 26508906; PMCID: PMC4614012.
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Exceptional response to nivolumab of a heavily pre-treated patient with metastatic renal-cell cancer: from a case report to molecular investigation and future perspectives.

Therapeutic advances in medical oncology

Dimitrakopoulos FD, Kourea E, Nasioulas G, Papadopoulou E, Nikolakopoulos A, Spyropoulou D, Kottorou A, Karatzas A, Kalofonos HP, Koutras A.
PMID: 32849917
Ther Adv Med Oncol. 2020 Aug 11;12:1758835920946152. doi: 10.1177/1758835920946152. eCollection 2020.

Immunotherapy may result in long-lasting exceptional clinical responses, the molecular background of which is inadequately understood. Here, we present the case of a 63-year-old patient with a past medical history of renal cancer who relapsed many years later. Several...

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Dimitrakopoulos FD, Kourea E, Nasioulas G, et al. Exceptional response to nivolumab of a heavily pre-treated patient with metastatic renal-cell cancer: from a case report to molecular investigation and future perspectives. Ther Adv Med Oncol. 2020;12:1758835920946152doi: 10.1177/1758835920946152.
Dimitrakopoulos, F. D., Kourea, E., Nasioulas, G., Papadopoulou, E., Nikolakopoulos, A., Spyropoulou, D., Kottorou, A., Karatzas, A., Kalofonos, H. P., & Koutras, A. (2020). Exceptional response to nivolumab of a heavily pre-treated patient with metastatic renal-cell cancer: from a case report to molecular investigation and future perspectives. Therapeutic advances in medical oncology, 121758835920946152. https://doi.org/10.1177/1758835920946152
Dimitrakopoulos, Foteinos-Ioannis D, et al. "Exceptional response to nivolumab of a heavily pre-treated patient with metastatic renal-cell cancer: from a case report to molecular investigation and future perspectives." Therapeutic advances in medical oncology vol. 12 (2020): 1758835920946152. doi: https://doi.org/10.1177/1758835920946152
Dimitrakopoulos FD, Kourea E, Nasioulas G, Papadopoulou E, Nikolakopoulos A, Spyropoulou D, Kottorou A, Karatzas A, Kalofonos HP, Koutras A. Exceptional response to nivolumab of a heavily pre-treated patient with metastatic renal-cell cancer: from a case report to molecular investigation and future perspectives. Ther Adv Med Oncol. 2020 Aug 11;12:1758835920946152. doi: 10.1177/1758835920946152. eCollection 2020. PMID: 32849917; PMCID: PMC7425249.
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A chemical energy approach of avascular tumor growth: multiscale modeling and qualitative results.

SpringerPlus

Ampatzoglou P, Dassios G, Hadjinicolaou M, Kourea HP, Vrahatis MN.
PMID: 26558163
Springerplus. 2015 Nov 02;4:660. doi: 10.1186/s40064-015-1417-5. eCollection 2015.

In the present manuscript we propose a lattice free multiscale model for avascular tumor growth that takes into account the biochemical environment, mitosis, necrosis, cellular signaling and cellular mechanics. This model extends analogous approaches by assuming a function that...

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Ampatzoglou P, Dassios G, Hadjinicolaou M, et al. A chemical energy approach of avascular tumor growth: multiscale modeling and qualitative results. Springerplus. 2015;4:660doi: 10.1186/s40064-015-1417-5.
Ampatzoglou, P., Dassios, G., Hadjinicolaou, M., Kourea, H. P., & Vrahatis, M. N. (2015). A chemical energy approach of avascular tumor growth: multiscale modeling and qualitative results. SpringerPlus, 4660. https://doi.org/10.1186/s40064-015-1417-5
Ampatzoglou, Pantelis, et al. "A chemical energy approach of avascular tumor growth: multiscale modeling and qualitative results." SpringerPlus vol. 4 (2015): 660. doi: https://doi.org/10.1186/s40064-015-1417-5
Ampatzoglou P, Dassios G, Hadjinicolaou M, Kourea HP, Vrahatis MN. A chemical energy approach of avascular tumor growth: multiscale modeling and qualitative results. Springerplus. 2015 Nov 02;4:660. doi: 10.1186/s40064-015-1417-5. eCollection 2015. PMID: 26558163; PMCID: PMC4630322.
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Relationship between Biochemical Bone Markers and Bone Mineral Density in Patients with Phenylketonuria under Restricted Diet.

Iranian journal of pediatrics

Koura HM, Zaki SM, Ismail NA, Salama EE, El Lebedy DH, Effat LK.
PMID: 25793041
Iran J Pediatr. 2014 Feb;24(1):23-8. Epub 2013 Dec 31.

OBJECTIVE: Most of phenylketonuria (PKU) develops bone turnover impairment and low bone mineral density (BMD). Measurements of BMD reflect only bone mineral status but not the dynamics of bone turnover. Bone markers are a noninvasive tool useful for the...

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Koura HM, Zaki SM, Ismail NA, et al. Relationship between Biochemical Bone Markers and Bone Mineral Density in Patients with Phenylketonuria under Restricted Diet. Iran J Pediatr. 2013;24(1):23-8
Koura, H. M., Zaki, S. M., Ismail, N. A., Salama, E. E., El Lebedy, D. H., & Effat, L. K. (2014). Relationship between Biochemical Bone Markers and Bone Mineral Density in Patients with Phenylketonuria under Restricted Diet. Iranian journal of pediatrics, 24(1), 23-8.
Koura, Hala M, et al. "Relationship between Biochemical Bone Markers and Bone Mineral Density in Patients with Phenylketonuria under Restricted Diet." Iranian journal of pediatrics vol. 24,1 (2014): 23-8.
Koura HM, Zaki SM, Ismail NA, Salama EE, El Lebedy DH, Effat LK. Relationship between Biochemical Bone Markers and Bone Mineral Density in Patients with Phenylketonuria under Restricted Diet. Iran J Pediatr. 2014 Feb;24(1):23-8. Epub 2013 Dec 31. PMID: 25793041; PMCID: PMC4359600.
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Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease.

Journal of inflammation (London, England)

Elshamaa MF, Sabry SM, Bazaraa HM, Koura HM, Elghoroury EA, Kantoush NA, Thabet EH, Abd-El Haleem DA.
PMID: 21859496
J Inflamm (Lond). 2011 Aug 23;8(1):20. doi: 10.1186/1476-9255-8-20.

AIM AND METHODS: We investigated the association between polymorphisms of the angiotensin converting enzyme-1 (ACE-1) and angiotensin II type one receptor (AT1RA1166C) genes and the causation of renal disease in 76 advanced chronic kidney disease (CKD) pediatric patients undergoing...

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Elshamaa MF, Sabry SM, Bazaraa HM, et al. Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease. J Inflamm (Lond). 2011;8(1):20doi: 10.1186/1476-9255-8-20.
Elshamaa, M. F., Sabry, S. M., Bazaraa, H. M., Koura, H. M., Elghoroury, E. A., Kantoush, N. A., Thabet, E. H., & Abd-El Haleem, D. A. (2011). Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease. Journal of inflammation (London, England), 8(1), 20. https://doi.org/10.1186/1476-9255-8-20
Elshamaa, Manal F, et al. "Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease." Journal of inflammation (London, England) vol. 8,1 (2011): 20. doi: https://doi.org/10.1186/1476-9255-8-20
Elshamaa MF, Sabry SM, Bazaraa HM, Koura HM, Elghoroury EA, Kantoush NA, Thabet EH, Abd-El Haleem DA. Genetic polymorphism of ACE and the angiotensin II type1 receptor genes in children with chronic kidney disease. J Inflamm (Lond). 2011 Aug 23;8(1):20. doi: 10.1186/1476-9255-8-20. PMID: 21859496; PMCID: PMC3167745.
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Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-based Regimens.

Cancer research and treatment

Kourea HP, Dimitrakopoulos FI, Koliou GA, Batistatou A, Papadopoulou K, Bobos M, Asimaki-Vlachopoulou A, Chrisafi S, Pavlakis K, Chatzopoulos K, Galani E, Pentheroudakis G, Pectasides D, Bafaloukos D, Res E, Papakostas P, Koutras A, Kotoula V, Fountzilas G.
PMID: 34793664
Cancer Res Treat. 2021 Nov 17; doi: 10.4143/crt.2021.748. Epub 2021 Nov 17.

PURPOSE: Angiogenesis is a crucial phenomenon in the development and progression of breast cancer (BC), but the clinical significance of angiogenesis-related proteins in metastatic BC remains unknown. This study investigates the prognostic value of vascular endothelial growth factor receptors...

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Kourea HP, Dimitrakopoulos FI, Koliou GA, et al. Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-based Regimens. Cancer Res Treat. 2021;doi: 10.4143/crt.2021.748.
Kourea, H. P., Dimitrakopoulos, F. I., Koliou, G. A., Batistatou, A., Papadopoulou, K., Bobos, M., Asimaki-Vlachopoulou, A., Chrisafi, S., Pavlakis, K., Chatzopoulos, K., Galani, E., Pentheroudakis, G., Pectasides, D., Bafaloukos, D., Res, E., Papakostas, P., Koutras, A., Kotoula, V., & Fountzilas, G. (2021). Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-based Regimens. Cancer research and treatment, . https://doi.org/10.4143/crt.2021.748
Kourea, Helen P, et al. "Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-based Regimens." Cancer research and treatment vol. (2021). doi: https://doi.org/10.4143/crt.2021.748
Kourea HP, Dimitrakopoulos FI, Koliou GA, Batistatou A, Papadopoulou K, Bobos M, Asimaki-Vlachopoulou A, Chrisafi S, Pavlakis K, Chatzopoulos K, Galani E, Pentheroudakis G, Pectasides D, Bafaloukos D, Res E, Papakostas P, Koutras A, Kotoula V, Fountzilas G. Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-based Regimens. Cancer Res Treat. 2021 Nov 17; doi: 10.4143/crt.2021.748. Epub 2021 Nov 17. PMID: 34793664.
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Showing 1 to 12 of 18 entries