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Showing 1 to 12 of 68 entries
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[Management of treatment in patients with neuroendocrine neoplasmas of digestive tract].

Vnitrni lekarstvi

Kiňová S, Kováčová M, Čaprnda M, Koreň M.
PMID: 26800468
Vnitr Lek. 2015;61:12-20.

UNLABELLED: Neuroendocrine neoplasmas are a form of cancer arising from cells of diffuse neuroendocrine system. They produce peptides or amines that act as hormones or neurotransmitters. Incidence of NENs is relatively low. Diagnostic work-up and treatment requires a multidisciplinary...

Xenobiotic metabolizing gene variants and renal cell cancer: a multicenter study.

Frontiers in oncology

Heck JE, Moore LE, Lee YC, McKay JD, Hung RJ, Karami S, Gaborieau V, Szeszenia-Dabrowska N, Zaridze DG, Mukeriya A, Mates D, Foretova L, Janout V, Kollárová H, Bencko V, Rothman N, Brennan P, Chow WH, Boffetta P.
PMID: 22645715
Front Oncol. 2012 Feb 20;2:16. doi: 10.3389/fonc.2012.00016. eCollection 2012.

BACKGROUND: The countries of Central and Eastern Europe have among the highest worldwide rates of renal cell cancer (RCC). Few studies have examined whether genetic variation in xenobiotic metabolic pathway genes may modify risk for this cancer.METHODS: The Central...

Synthesis of N-aryl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridin-7-amines and their photodynamic properties in the human skin melanoma cell line G361.

Bioorganic chemistry

Razmienė B, Vojáčková V, Řezníčková E, Malina L, Dambrauskienė V, Kubala M, Bajgar R, Kolářová H, Žukauskaitė A, Arbačiauskienė E, Šačkus A, Kryštof V.
PMID: 34953323
Bioorg Chem. 2021 Dec 16;119:105570. doi: 10.1016/j.bioorg.2021.105570. Epub 2021 Dec 16.

A small series of N-aryl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridin-7-amines was synthesized from easily accessible 1-phenyl-1H-pyrazol-3-ol via 7-iodo-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridine and 7-iodo-4-methyl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridine intermediates and their subsequent use in palladium catalyzed Buchwald-Hartwig cross-coupling reaction with various anilines. Majority of the compounds were not significantly cytotoxic to melanoma...

Synthesis of N-aryl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridin-7-amines and their photodynamic properties in the human skin melanoma cell line G361.

Bioorganic chemistry

Razmienė B, Vojáčková V, Řezníčková E, Malina L, Dambrauskienė V, Kubala M, Bajgar R, Kolářová H, Žukauskaitė A, Arbačiauskienė E, Šačkus A, Kryštof V.
PMID: 34953323
Bioorg Chem. 2021 Dec 16;119:105570. doi: 10.1016/j.bioorg.2021.105570. Epub 2021 Dec 16.

A small series of N-aryl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridin-7-amines was synthesized from easily accessible 1-phenyl-1H-pyrazol-3-ol via 7-iodo-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridine and 7-iodo-4-methyl-2,6-diphenyl-2H-pyrazolo[4,3-c]pyridine intermediates and their subsequent use in palladium catalyzed Buchwald-Hartwig cross-coupling reaction with various anilines. Majority of the compounds were not significantly cytotoxic to melanoma...

Detection of Antimicrobial Resistance of Bacteria .

Antibiotics (Basel, Switzerland)

Regecová I, Výrostková J, Zigo F, Gregová G, Kováčová M.
PMID: 34066038
Antibiotics (Basel). 2021 May 12;10(5). doi: 10.3390/antibiotics10050570.

Antimicrobial and multidrug resistance is detected in nonaureus staphylococci, including

Sleep Characteristics According to Gender and Age Measured by Wrist Actigraphy.

International journal of environmental research and public health

Kováčová K, Stebelová K.
PMID: 34948821
Int J Environ Res Public Health. 2021 Dec 15;18(24). doi: 10.3390/ijerph182413213.

The sleep/wake rhythm is one of the most important biological rhythms. Quality and duration of sleep change during lifetime. The aim of our study was to determine differences in sleep efficiency, movement, and fragmentation during sleep period between genders...

Contribution of the multi-echo approach in accelerated functional magnetic resonance imaging multiband acquisition.

Human brain mapping

Kovářová A, Gajdoš M, Rektor I, Mikl M.
PMID: 34716738
Hum Brain Mapp. 2021 Oct 30; doi: 10.1002/hbm.25698. Epub 2021 Oct 30.

We wanted to verify the effect of combining multi-echo (ME) functional magnetic resonance imaging (fMRI) with slice acceleration in simultaneous multi-slice acquisition. The aim was to shed light on the benefits of multiple echoes for various acquisition settings, especially...

Tuneable in-situ nanoCT workflow using FIB/SEM.

Ultramicroscopy

Barabasová P, Kováčová V, Stejskal P, Unčovský M, Valterová E, Vystavěl T.
PMID: 33906009
Ultramicroscopy. 2021 Jun;225:113283. doi: 10.1016/j.ultramic.2021.113283. Epub 2021 Apr 15.

Inspired by the standard computed tomography, a new method of 3D X-ray imaging embedded in FIB-SEM microscope is proposed. The unique combination of TEM-like specimen stage enabling in lens STEM detection (referred to as CompuStage), nanomanipulator (referred to as...

Neurocognitive performance in relapsing-remitting multiple sclerosis patients is associated with metabolic abnormalities of the thalamus but not the hippocampus- GABA-edited 1H MRS study.

Neurological research

Kantorová E, Hnilicová P, Bogner W, Grendár M, Grossmann J, Kováčová S, Hečková E, Strasser B, Čierny D, Zeleňák K, Kurča E.
PMID: 34313578
Neurol Res. 2022 Jan;44(1):57-64. doi: 10.1080/01616412.2021.1956282. Epub 2021 Jul 27.

OBJECTIVES: Multiple sclerosis (MS) is an inflammatory demyelinating disease that may cause physical disabling as well as cognitive dysfunction. The presented study investigated how the neuropsychological status depends on the thalamus and hippocampus's metabolic processes, using γ-aminobutyric acid-edited magnetic...

Contribution of the multi-echo approach in accelerated functional magnetic resonance imaging multiband acquisition.

Human brain mapping

Kovářová A, Gajdoš M, Rektor I, Mikl M.
PMID: 34716738
Hum Brain Mapp. 2022 Feb 15;43(3):955-973. doi: 10.1002/hbm.25698. Epub 2021 Oct 30.

We wanted to verify the effect of combining multi-echo (ME) functional magnetic resonance imaging (fMRI) with slice acceleration in simultaneous multi-slice acquisition. The aim was to shed light on the benefits of multiple echoes for various acquisition settings, especially...

3D Echocardiography - A Useful Method for Cardiovascular Risk Assessment in End-Stage Renal Disease Patients.

Physiological research

Kovářová M, Žilinská Z, Páleš J, Kužmová Z, Gažová A, Smaha J, Kužma M, Jackuliak P, Štvrtinová V, Kyselovič J, Payer J.
PMID: 34918535
Physiol Res. 2021 Nov 30;70:S109-S120. doi: 10.33549/physiolres.934782.

Patients with chronic kidney disease (CKD) have an increased risk of premature mortality, mainly due to cardiovascular causes. The association between hemodialysis and accelerated atherosclerosis has long been described. The ankle-brachial index (ABI) is a surrogate marker of atherosclerosis...

Sustainable One-Step Solid-State Synthesis of Antibacterially Active Silver Nanoparticles Using Mechanochemistry.

Nanomaterials (Basel, Switzerland)

Kováčová M, Daneu N, Tkáčiková Ľ, Búreš R, Dutková E, Stahorský M, Bujňáková ZL, Baláž M.
PMID: 33113789
Nanomaterials (Basel). 2020 Oct 25;10(11). doi: 10.3390/nano10112119.

A combination of solid-state mechanochemical and green approaches for the synthesis of silver nanoparticles (AgNPs) is explored in this study.

Showing 1 to 12 of 68 entries