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Showing 1 to 12 of 194 entries
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ADVANCING women academic faculty in STEM careers: The role of critical HRD in supporting diversity and inclusion

STEM and diversity

Hutchins HM, Kovach JV.
GSID: SVF8D5i_7HoJ
HM Hutchins, JV Kovach - Advances in Developing Human …, 2019 - journals.sagepub.com

… of STEM women and WoC faculty in rank, increased diversity of STEM faculty applicants, improved diversity and … , and expanded access and availability of diversity resources and data. …

Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.

JACC. Clinical electrophysiology

Tisdale JE, Jaynes HA, Overholser BR, Sowinski KM, Flockhart DA, Kovacs RJ.
PMID: 28451647
JACC Clin Electrophysiol. 2016 Dec;2(7):765-774. doi: 10.1016/j.jacep.2016.02.015.

OBJECTIVES: We tested the hypothesis that oral progesterone administration attenuates drug-induced QT interval lengthening.BACKGROUND: Evidence from preclinical and human investigations suggests that higher serum progesterone concentrations may be protective against drug-induced QT interval lengthening.METHODS: In this prospective, double-blind, crossover...

Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads.

BioData mining

Liang M, Raley C, Zheng X, Kutty G, Gogineni E, Sherman BT, Sun Q, Chen X, Skelly T, Jones K, Stephens R, Zhou B, Lau W, Johnson C, Imamichi T, Jiang M, Dewar R, Lempicki RA, Tran B, Kovacs JA, Huang DW.
PMID: 27051465
BioData Min. 2016 Apr 05;9:13. doi: 10.1186/s13040-016-0090-8. eCollection 2016.

BACKGROUND: Gene isoforms are commonly found in both prokaryotes and eukaryotes. Since each isoform may perform a specific function in response to changing environmental conditions, studying the dynamics of gene isoforms is important in understanding biological processes and disease...

Editorial Comment.

Urology

Kovac JR.
PMID: 28666654
Urology. 2017 Aug;106:101-102. doi: 10.1016/j.urology.2017.03.065. Epub 2017 Jun 27.

No abstract available.

Spray Layer-by-Layer Assembled Clay Composite Thin Films as Selective Layers in Reverse Osmosis Membranes.

ACS applied materials & interfaces

Kovacs JR, Liu C, Hammond PT.
PMID: 26058008
ACS Appl Mater Interfaces. 2015 Jun 24;7(24):13375-83. doi: 10.1021/acsami.5b01879. Epub 2015 Jun 09.

Spray layer-by-layer assembled thin films containing laponite (LAP) clay exhibit effective salt barrier and water permeability properties when applied as selective layers in reverse osmosis (RO) membranes. Negatively charged LAP platelets were layered with poly(diallyldimethylammonium) (PDAC), poly(allylamine) (PAH), and...

A critical analysis of testosterone supplementation therapy and cardiovascular risk in elderly men.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Scovell J, Ramasamy R, Kovac JR.
PMID: 24940464
Can Urol Assoc J. 2014 May;8(5):E356-7. doi: 10.5489/cuaj.1962.

No abstract available.

Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response.

Clinical pharmacology : advances and applications

Kreutz RP, Owens J, Jin Y, Nystrom P, Desta Z, Kreutz Y, Breall JA, Li L, Chiang C, Kovacs RJ, Flockhart DA.
PMID: 24353446
Clin Pharmacol. 2013 Dec 09;5:185-92. doi: 10.2147/CPAA.S53151. eCollection 2013.

Recent candidate gene studies using a human liver bank and in vivo validation in healthy volunteers identified polymorphisms in cytochrome P450 (CYP) 3A4 gene (CYP3A4*22), Ah-receptor nuclear translocator (ARNT), and peroxisome proliferator-activated receptor-α (PPAR-α) genes that are associated with...

Drug resistance in cortical and hippocampal slices from resected tissue of epilepsy patients: no significant impact of p-glycoprotein and multidrug resistance-associated proteins.

Frontiers in neurology

Sandow N, Kim S, Raue C, Päsler D, Klaft ZJ, Antonio LL, Hollnagel JO, Kovacs R, Kann O, Horn P, Vajkoczy P, Holtkamp M, Meencke HJ, Cavalheiro EA, Pragst F, Gabriel S, Lehmann TN, Heinemann U.
PMID: 25741317
Front Neurol. 2015 Feb 18;6:30. doi: 10.3389/fneur.2015.00030. eCollection 2015.

Drug resistant patients undergoing epilepsy surgery have a good chance to become sensitive to anticonvulsant medication, suggesting that the resected brain tissue is responsible for drug resistance. Here, we address the question whether P-glycoprotein (Pgp) and multidrug resistance-associated proteins...

The atlasia reflexes and the perforation of the caves.

Journal francais de medecine et chirurgie thoraciques

KOVACS J.
PMID: 18107164
J Fr Med Chir Thorac. 1948;2(6):524-33.

No abstract available.

Comparison of Structurally-Related Alkoxide, Amine, and Thiolate-Ligated M (M= Fe, Co) Complexes: the Influence of Thiolates on the Properties of Biologically Relevant Metal Complexes.

Inorganica chimica acta

Brines LM, Villar-Acevedo G, Kitagawa T, Swartz RD, Lugo-Mas P, Kaminsky W, Benedict JB, Kovacs JA.
PMID: 21731109
Inorganica Chim Acta. 2008 Mar 03;361(4):1070-1078. doi: 10.1016/j.ica.2007.07.038.

Mechanistic pathways of metalloenzymes are controlled by the metal ion's electronic and magnetic properties, which are tuned by the coordinated ligands. The functional advantage gained by incorporating cysteinates into the active site of non-heme iron enzymes such as superoxide...

Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response.

Clinical pharmacology : advances and applications

Kreutz RP, Nystrom P, Kreutz Y, Miao J, Desta Z, Breall JA, Li L, Chiang C, Kovacs R, Flockhart DA, Jin Y.
PMID: 22427735
Clin Pharmacol. 2012;4:13-20. doi: 10.2147/CPAA.S27822. Epub 2012 Feb 20.

BACKGROUND: The metabolic activation of clopidogrel is a two-step process. It has been suggested that paraoxonase-1 (PON1) is a rate-limiting enzyme in the conversion of 2-oxo- clopidogrel to an active thiol metabolite. Conflicting results have been reported in regard...

Thriving in an academic environment.

Research in nursing & health

Kovach CR.
PMID: 15042633
Res Nurs Health. 2004 Apr;27(2):73-4. doi: 10.1002/nur.20010.

No abstract available.

Showing 1 to 12 of 194 entries