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Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.

JACC. Clinical electrophysiology

Tisdale JE, Jaynes HA, Overholser BR, Sowinski KM, Flockhart DA, Kovacs RJ.
PMID: 28451647
JACC Clin Electrophysiol. 2016 Dec;2(7):765-774. doi: 10.1016/j.jacep.2016.02.015.

OBJECTIVES: We tested the hypothesis that oral progesterone administration attenuates drug-induced QT interval lengthening.BACKGROUND: Evidence from preclinical and human investigations suggests that higher serum progesterone concentrations may be protective against drug-induced QT interval lengthening.METHODS: In this prospective, double-blind, crossover...

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Tisdale JE, Jaynes HA, Overholser BR, et al. Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study. JACC Clin Electrophysiol. 2016;2(7):765-774doi: 10.1016/j.jacep.2016.02.015.
Tisdale, J. E., Jaynes, H. A., Overholser, B. R., Sowinski, K. M., Flockhart, D. A., & Kovacs, R. J. (2016). Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study. JACC. Clinical electrophysiology, 2(7), 765-774. https://doi.org/10.1016/j.jacep.2016.02.015
Tisdale, James E, et al. "Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study." JACC. Clinical electrophysiology vol. 2,7 (2016): 765-774. doi: https://doi.org/10.1016/j.jacep.2016.02.015
Tisdale JE, Jaynes HA, Overholser BR, Sowinski KM, Flockhart DA, Kovacs RJ. Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study. JACC Clin Electrophysiol. 2016 Dec;2(7):765-774. doi: 10.1016/j.jacep.2016.02.015. PMID: 28451647; PMCID: PMC5403156.
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High-density lipoprotein endocytosis in endothelial cells.

World journal of biological chemistry

Fruhwürth S, Pavelka M, Bittman R, Kovacs WJ, Walter KM, Röhrl C, Stangl H.
PMID: 24340136
World J Biol Chem. 2013 Nov 26;4(4):131-40. doi: 10.4331/wjbc.v4.i4.131.

AIM: To describe the way stations of high-density lipoprotein (HDL) uptake and its lipid exchange in endothelial cells in vitro and in vivo.METHODS: A combination of fluorescence microscopy using novel fluorescent cholesterol surrogates and electron microscopy was used to...

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Fruhwürth S, Pavelka M, Bittman R, et al. High-density lipoprotein endocytosis in endothelial cells. World J Biol Chem. 2013;4(4):131-40doi: 10.4331/wjbc.v4.i4.131.
Fruhwürth, S., Pavelka, M., Bittman, R., Kovacs, W. J., Walter, K. M., Röhrl, C., & Stangl, H. (2013). High-density lipoprotein endocytosis in endothelial cells. World journal of biological chemistry, 4(4), 131-40. https://doi.org/10.4331/wjbc.v4.i4.131
Fruhwürth, Stefanie, et al. "High-density lipoprotein endocytosis in endothelial cells." World journal of biological chemistry vol. 4,4 (2013): 131-40. doi: https://doi.org/10.4331/wjbc.v4.i4.131
Fruhwürth S, Pavelka M, Bittman R, Kovacs WJ, Walter KM, Röhrl C, Stangl H. High-density lipoprotein endocytosis in endothelial cells. World J Biol Chem. 2013 Nov 26;4(4):131-40. doi: 10.4331/wjbc.v4.i4.131. PMID: 24340136; PMCID: PMC3856308.
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Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response.

Clinical pharmacology : advances and applications

Kreutz RP, Owens J, Jin Y, Nystrom P, Desta Z, Kreutz Y, Breall JA, Li L, Chiang C, Kovacs RJ, Flockhart DA.
PMID: 24353446
Clin Pharmacol. 2013 Dec 09;5:185-92. doi: 10.2147/CPAA.S53151. eCollection 2013.

Recent candidate gene studies using a human liver bank and in vivo validation in healthy volunteers identified polymorphisms in cytochrome P450 (CYP) 3A4 gene (CYP3A4*22), Ah-receptor nuclear translocator (ARNT), and peroxisome proliferator-activated receptor-α (PPAR-α) genes that are associated with...

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Kreutz RP, Owens J, Jin Y, et al. Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response. Clin Pharmacol. 2013;5:185-92doi: 10.2147/CPAA.S53151.
Kreutz, R. P., Owens, J., Jin, Y., Nystrom, P., Desta, Z., Kreutz, Y., Breall, J. A., Li, L., Chiang, C., Kovacs, R. J., & Flockhart, D. A. (2013). Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response. Clinical pharmacology : advances and applications, 5185-92. https://doi.org/10.2147/CPAA.S53151
Kreutz, Rolf P, et al. "Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response." Clinical pharmacology : advances and applications vol. 5 (2013): 185-92. doi: https://doi.org/10.2147/CPAA.S53151
Kreutz RP, Owens J, Jin Y, Nystrom P, Desta Z, Kreutz Y, Breall JA, Li L, Chiang C, Kovacs RJ, Flockhart DA. Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response. Clin Pharmacol. 2013 Dec 09;5:185-92. doi: 10.2147/CPAA.S53151. eCollection 2013. PMID: 24353446; PMCID: PMC3862586.
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Proximal Biceps Tenodesis: An Anatomic Study and Comparison of the Accuracy of Arthroscopic and Open Techniques Using Interference Screws.

Orthopaedic journal of sports medicine

Kovack TJ, Idoine JD, Jacob PB.
PMID: 26535300
Orthop J Sports Med. 2014 Feb 19;2(2):2325967114522198. doi: 10.1177/2325967114522198. eCollection 2014 Feb.

PURPOSE: To (1) better define the anatomy of the proximal shoulder in relation to the long head of the biceps tendon, (2) compare the length-tension relationship of the biceps tendon in the native shoulder with that after arthroscopic and...

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Kovack TJ, Idoine JD, Jacob PB. Proximal Biceps Tenodesis: An Anatomic Study and Comparison of the Accuracy of Arthroscopic and Open Techniques Using Interference Screws. Orthop J Sports Med. 2014;2(2):2325967114522198doi: 10.1177/2325967114522198.
Kovack, T. J., Idoine, J. D., & Jacob, P. B. (2014). Proximal Biceps Tenodesis: An Anatomic Study and Comparison of the Accuracy of Arthroscopic and Open Techniques Using Interference Screws. Orthopaedic journal of sports medicine, 2(2), 2325967114522198. https://doi.org/10.1177/2325967114522198
Kovack, Thomas J, et al. "Proximal Biceps Tenodesis: An Anatomic Study and Comparison of the Accuracy of Arthroscopic and Open Techniques Using Interference Screws." Orthopaedic journal of sports medicine vol. 2,2 (2014): 2325967114522198. doi: https://doi.org/10.1177/2325967114522198
Kovack TJ, Idoine JD, Jacob PB. Proximal Biceps Tenodesis: An Anatomic Study and Comparison of the Accuracy of Arthroscopic and Open Techniques Using Interference Screws. Orthop J Sports Med. 2014 Feb 19;2(2):2325967114522198. doi: 10.1177/2325967114522198. eCollection 2014 Feb. PMID: 26535300; PMCID: PMC4555622.
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MGUS: not so benign after all.

Blood

Kovacs MJ.
PMID: 18948581
Blood. 2008 Nov 01;112(9):3533. doi: 10.1182/blood-2008-07-167700.

No abstract available.

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Kovacs MJ. MGUS: not so benign after all. Blood. 2008;112(9):3533doi: 10.1182/blood-2008-07-167700.
Kovacs, M. J. (2008). MGUS: not so benign after all. Blood, 112(9), 3533. https://doi.org/10.1182/blood-2008-07-167700
Kovacs, Michael J. "MGUS: not so benign after all." Blood vol. 112,9 (2008): 3533. doi: https://doi.org/10.1182/blood-2008-07-167700
Kovacs MJ. MGUS: not so benign after all. Blood. 2008 Nov 01;112(9):3533. doi: 10.1182/blood-2008-07-167700. PMID: 18948581; PMCID: PMC2572784.
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The atlasia reflexes and the perforation of the caves.

Journal francais de medecine et chirurgie thoraciques

KOVACS J.
PMID: 18107164
J Fr Med Chir Thorac. 1948;2(6):524-33.

No abstract available.

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KOVACS J. L'atélectasie réflexe et la perforation des cavernes. The atlasia reflexes and the perforation of the caves. J Fr Med Chir Thorac. 1948;2(6):524-33
KOVACS, J. (1948). L'atélectasie réflexe et la perforation des cavernes. The atlasia reflexes and the perforation of the caves. Journal francais de medecine et chirurgie thoraciques, 2(6), 524-33.
KOVACS, J. "L'atélectasie réflexe et la perforation des cavernes." The atlasia reflexes and the perforation of the caves. Journal francais de medecine et chirurgie thoraciques vol. 2,6 (1948): 524-33.
KOVACS J. L'atélectasie réflexe et la perforation des cavernes. The atlasia reflexes and the perforation of the caves. J Fr Med Chir Thorac. 1948;2(6):524-33. French. PMID: 18107164.
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Energy Distribution in the PSF for an Arbitrary, Passband.

Applied optics

Kovach WS.
PMID: 20134566
Appl Opt. 1974 Aug 01;13(8):1769-71. doi: 10.1364/AO.13.001769.

No abstract available.

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Kovach WS. Energy Distribution in the PSF for an Arbitrary, Passband. Appl Opt. 1974;13(8):1769-71doi: 10.1364/AO.13.001769.
Kovach, W. S. (1974). Energy Distribution in the PSF for an Arbitrary, Passband. Applied optics, 13(8), 1769-71. https://doi.org/10.1364/AO.13.001769
Kovach, W S. "Energy Distribution in the PSF for an Arbitrary, Passband." Applied optics vol. 13,8 (1974): 1769-71. doi: https://doi.org/10.1364/AO.13.001769
Kovach WS. Energy Distribution in the PSF for an Arbitrary, Passband. Appl Opt. 1974 Aug 01;13(8):1769-71. doi: 10.1364/AO.13.001769. PMID: 20134566.
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D-dimer levels < 250 ng/mL after oral anticoagulation predicted a low risk for recurrent venous thromboembolism.

ACP journal club

Kovacs MJ.
PMID: 15122870
ACP J Club. 2004 Mar-Apr;140(2):50.

No abstract available.

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Kovacs MJ. D-dimer levels < 250 ng/mL after oral anticoagulation predicted a low risk for recurrent venous thromboembolism. ACP J Club. 2004;140(2):50
Kovacs, M. J. (2004). D-dimer levels < 250 ng/mL after oral anticoagulation predicted a low risk for recurrent venous thromboembolism. ACP journal club, 140(2), 50.
Kovacs, Michael J. "D-dimer levels < 250 ng/mL after oral anticoagulation predicted a low risk for recurrent venous thromboembolism." ACP journal club vol. 140,2 (2004): 50.
Kovacs MJ. D-dimer levels < 250 ng/mL after oral anticoagulation predicted a low risk for recurrent venous thromboembolism. ACP J Club. 2004 Mar-Apr;140(2):50. PMID: 15122870.
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Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells.

Journal of inflammation research

Vanhorn J, Altenburg JD, Harvey KA, Xu Z, Kovacs RJ, Siddiqui RA.
PMID: 22442634
J Inflamm Res. 2012;5:37-50. doi: 10.2147/JIR.S29044. Epub 2012 Mar 14.

Niacin, also known as nicotinic acid, is an organic compound that has several cardio-beneficial effects. However, its use is limited due to the induction of a variable flushing response in most individuals. Flushing occurs from a niacin receptor mediated...

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Vanhorn J, Altenburg JD, Harvey KA, et al. Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells. J Inflamm Res. 2012;5:37-50doi: 10.2147/JIR.S29044.
Vanhorn, J., Altenburg, J. D., Harvey, K. A., Xu, Z., Kovacs, R. J., & Siddiqui, R. A. (2012). Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells. Journal of inflammation research, 537-50. https://doi.org/10.2147/JIR.S29044
Vanhorn, Justin, et al. "Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells." Journal of inflammation research vol. 5 (2012): 37-50. doi: https://doi.org/10.2147/JIR.S29044
Vanhorn J, Altenburg JD, Harvey KA, Xu Z, Kovacs RJ, Siddiqui RA. Attenuation of niacin-induced prostaglandin D(2) generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells. J Inflamm Res. 2012;5:37-50. doi: 10.2147/JIR.S29044. Epub 2012 Mar 14. PMID: 22442634; PMCID: PMC3308705.
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Dysregulation of neutrophil CXCR2 and pulmonary endothelial icam-1 promotes age-related pulmonary inflammation.

Aging and disease

Nomellini V, Brubaker AL, Mahbub S, Palmer JL, Gomez CR, Kovacs EJ.
PMID: 22724082
Aging Dis. 2012 Jun;3(3):234-47. Epub 2012 Feb 28.

We have previously demonstrated that aging is associated with prolonged pulmonary inflammation in a murine model of thermal injury. To further investigate these observations, we examined lung congestion, markers of neutrophil chemotaxis and adhesion, and lung endothelia responses in...

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Nomellini V, Brubaker AL, Mahbub S, et al. Dysregulation of neutrophil CXCR2 and pulmonary endothelial icam-1 promotes age-related pulmonary inflammation. Aging Dis. 2012;3(3):234-47
Nomellini, V., Brubaker, A. L., Mahbub, S., Palmer, J. L., Gomez, C. R., & Kovacs, E. J. (2012). Dysregulation of neutrophil CXCR2 and pulmonary endothelial icam-1 promotes age-related pulmonary inflammation. Aging and disease, 3(3), 234-47.
Nomellini, Vanessa, et al. "Dysregulation of neutrophil CXCR2 and pulmonary endothelial icam-1 promotes age-related pulmonary inflammation." Aging and disease vol. 3,3 (2012): 234-47.
Nomellini V, Brubaker AL, Mahbub S, Palmer JL, Gomez CR, Kovacs EJ. Dysregulation of neutrophil CXCR2 and pulmonary endothelial icam-1 promotes age-related pulmonary inflammation. Aging Dis. 2012 Jun;3(3):234-47. Epub 2012 Feb 28. PMID: 22724082; PMCID: PMC3375080.
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Attenuated total reflection angular spectra and associated resonant electromagnetic oscillations of a dielectric slab bounded by Ag films.

Applied optics

Kovacs GJ, Scott GD.
PMID: 20203968
Appl Opt. 1978 Oct 15;17(20):3314-22. doi: 10.1364/AO.17.003314.

The attenuated total reflection (ATR) angular spectra of a layered system of Ag-MgF(2)-Ag, sandwiched between glass and air, have been measured at three different wavelengths in the visible region. Resonant electromagnetic (EM) oscillations are detected as narrow minima in...

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Kovacs GJ, Scott GD. Attenuated total reflection angular spectra and associated resonant electromagnetic oscillations of a dielectric slab bounded by Ag films. Appl Opt. 1978;17(20):3314-22doi: 10.1364/AO.17.003314.
Kovacs, G. J., & Scott, G. D. (1978). Attenuated total reflection angular spectra and associated resonant electromagnetic oscillations of a dielectric slab bounded by Ag films. Applied optics, 17(20), 3314-22. https://doi.org/10.1364/AO.17.003314
Kovacs, G J, and Scott, G D. "Attenuated total reflection angular spectra and associated resonant electromagnetic oscillations of a dielectric slab bounded by Ag films." Applied optics vol. 17,20 (1978): 3314-22. doi: https://doi.org/10.1364/AO.17.003314
Kovacs GJ, Scott GD. Attenuated total reflection angular spectra and associated resonant electromagnetic oscillations of a dielectric slab bounded by Ag films. Appl Opt. 1978 Oct 15;17(20):3314-22. doi: 10.1364/AO.17.003314. PMID: 20203968.
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Survival and cell mediated immunity after burn injury in aged mice.

Journal of the American Aging Association

Kovacs EJ, Grabowski KA, Duffner LA, Plackett TP, Gregory MS.
PMID: 23604885
J Am Aging Assoc. 2002 Jan;25(1):3-9. doi: 10.1007/s11357-002-0001-4.

The elderly are less able to survive burn injury than young healthy individuals. Regardless of age, burn victims often succumb to secondary infections rather than the primary injury. Since immune responses diminish with age, it is likely that aged...

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Kovacs EJ, Grabowski KA, Duffner LA, et al. Survival and cell mediated immunity after burn injury in aged mice. J Am Aging Assoc. 2002;25(1):3-9doi: 10.1007/s11357-002-0001-4.
Kovacs, E. J., Grabowski, K. A., Duffner, L. A., Plackett, T. P., & Gregory, M. S. (2002). Survival and cell mediated immunity after burn injury in aged mice. Journal of the American Aging Association, 25(1), 3-9. https://doi.org/10.1007/s11357-002-0001-4
Kovacs, Elizabeth J, et al. "Survival and cell mediated immunity after burn injury in aged mice." Journal of the American Aging Association vol. 25,1 (2002): 3-9. doi: https://doi.org/10.1007/s11357-002-0001-4
Kovacs EJ, Grabowski KA, Duffner LA, Plackett TP, Gregory MS. Survival and cell mediated immunity after burn injury in aged mice. J Am Aging Assoc. 2002 Jan;25(1):3-9. doi: 10.1007/s11357-002-0001-4. PMID: 23604885; PMCID: PMC3455289.
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Showing 1 to 12 of 163 entries