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Showing 1 to 12 of 16 entries
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HyperLabels: Browsing of Dense and Hierarchical Molecular 3D Models.

IEEE transactions on visualization and computer graphics

Kouril D, Isenberg T, Kozlikova B, Meyer M, Groller ME, Viola I.
PMID: 32092008
IEEE Trans Vis Comput Graph. 2021 Aug;27(8):3493-3504. doi: 10.1109/TVCG.2020.2975583. Epub 2021 Jun 30.

We present a method for the browsing of hierarchical 3D models in which we combine the typical navigation of hierarchical structures in a 2D environment-using clicks on nodes, links, or icons-with a 3D spatial data visualization. Our approach is...

[Psychologic causes of erectile dysfunction].

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti

Weiss P, Urbánek V, Kozmiková T.
PMID: 9471764
Rozhl Chir. 1997 Sep;76(9):411-4.

The authors discuss the most frequent psychological causes of impaired erectility. The most important psychogenic factors for the development and persistence of erectile impairment is in their opinion anticipative anxiety, performance orientation, the partner's negative reaction to rare failure,...

Alkaloid Escholidine and Its Interaction with DNA Structures.

Biology

Jarošová P, Hannig P, Kolková K, Mazzini S, Táborská E, Gargallo R, Borgonovo G, Artali R, Táborský P.
PMID: 34943140
Biology (Basel). 2021 Nov 24;10(12). doi: 10.3390/biology10121225.

Berberine, the most known quaternary protoberberine alkaloid (QPA), has been reported to inhibit the SIK3 protein connected with breast cancer. Berberine also appears to reduce the bcl-2 and XIAP expression-proteins responsible for the inhibition of apoptosis. As some problems...

ChemVA: Interactive Visual Analysis of Chemical Compound Similarity in Virtual Screening.

IEEE transactions on visualization and computer graphics

Sabando MV, Ulbrich P, Selzer M, Byska J, Mican J, Ponzoni I, Soto AJ, Ganuza ML, Kozlikova B.
PMID: 33048734
IEEE Trans Vis Comput Graph. 2021 Feb;27(2):891-901. doi: 10.1109/TVCG.2020.3030438. Epub 2021 Jan 29.

In the modern drug discovery process, medicinal chemists deal with the complexity of analysis of large ensembles of candidate molecules. Computational tools, such as dimensionality reduction (DR) and classification, are commonly used to efficiently process the multidimensional space of...

[QT interval dispersion in hypertensive diabetics and in patients with hypertension with chronic heart failure without diabetes].

Vnitrni lekarstvi

Radman A, Murín J, Bulas J, Reptová A, Ravingerová T, Mikes P, Kozliková K, Ghanem W, Jaber J, Baqi L.
PMID: 14682153
Vnitr Lek. 2003 Oct;49(10):802-7.

AIM: Our aim was to: 1. compare QT dispersion from routine ECG in diabetic and no-diabetic patients with congestive heart failure, 2. describe associations between QT dispersion and circadian blood (BP) pressure variation in type 2 diabetic patients with...

Alkaloid Escholidine and Its Interaction with DNA Structures.

Biology

Jarošová P, Hannig P, Kolková K, Mazzini S, Táborská E, Gargallo R, Borgonovo G, Artali R, Táborský P.
PMID: 34943140
Biology (Basel). 2021 Nov 24;10(12). doi: 10.3390/biology10121225.

Berberine, the most known quaternary protoberberine alkaloid (QPA), has been reported to inhibit the SIK3 protein connected with breast cancer. Berberine also appears to reduce the bcl-2 and XIAP expression-proteins responsible for the inhibition of apoptosis. As some problems...

Labels on Levels: Labeling of Multi-Scale Multi-Instance and Crowded 3D Biological Environments.

IEEE transactions on visualization and computer graphics

Kouril D, Cmolik L, Kozlikova B, Wu HY, Johnson G, Goodsell DS, Olson A, Groller ME, Viola I.
PMID: 30130195
IEEE Trans Vis Comput Graph. 2019 Jan;25(1):977-986. doi: 10.1109/TVCG.2018.2864491. Epub 2018 Dec 09.

Labeling is intrinsically important for exploring and understanding complex environments and models in a variety of domains. We present a method for interactive labeling of crowded 3D scenes containing very many instances of objects spanning multiple scales in size....

Vivern A Virtual Environment for Multiscale Visualization and Modeling of DNA Nanostructures.

IEEE transactions on visualization and computer graphics

Kutak D, Selzer MN, Byska J, Ganuza ML, Barisic I, Kozlikova B, Miao H.
PMID: 34437064
IEEE Trans Vis Comput Graph. 2021 Aug 26; doi: 10.1109/TVCG.2021.3106328. Epub 2021 Aug 26.

DNA nanostructures offer promising applications, particularly in the biomedical domain, as they can be used for targeted drug delivery, construction of nanorobots, or as a basis for molecular motors. One of the most prominent techniques for assembling these structures...

LoopGrafter: Visual Support for the Grafting Workflow of Protein Loops.

IEEE transactions on visualization and computer graphics

Opaleny F, Ulbrich P, Planas-Iglesias J, Byska J, Pinto GP, Bednar D, FurmanovA K, KozlikovA B.
PMID: 34587016
IEEE Trans Vis Comput Graph. 2021 Sep 29; doi: 10.1109/TVCG.2021.3114755. Epub 2021 Sep 29.

In the process of understanding and redesigning the function of proteins in modern biochemistry, protein engineers are increasingly focusing on the exploration of regions in proteins called loops. Analyzing various characteristics of these regions helps the experts to design...

[Surface integral maps, their characteristics and methods of quantitative analysis].

Bratislavske lekarske listy

Kozlíková K.
PMID: 2265366
Bratisl Lek Listy. 1990 Nov;91(11):815-23.

Integral maps (IM) enable considerable reduction of measured data with preservation of all characteristics of electric field of the heart with exception of the time sequence of activation. Review article offers a definition of the term IM and explains...

Alkaloid Escholidine and Its Interaction with DNA Structures.

Biology

Jarošová P, Hannig P, Kolková K, Mazzini S, Táborská E, Gargallo R, Borgonovo G, Artali R, Táborský P.
PMID: 34943140
Biology (Basel). 2021 Nov 24;10(12). doi: 10.3390/biology10121225.

Berberine, the most known quaternary protoberberine alkaloid (QPA), has been reported to inhibit the SIK3 protein connected with breast cancer. Berberine also appears to reduce the bcl-2 and XIAP expression-proteins responsible for the inhibition of apoptosis. As some problems...

Subphthalocyanines as Efficient Photosensitizers with Nanomolar Photodynamic Activity against Cancer Cells.

Journal of medicinal chemistry

Demuth J, Gallego L, Kozlikova M, Machacek M, Kucera R, Torres T, Martinez-Diaz MV, Novakova V.
PMID: 34813305
J Med Chem. 2021 Dec 09;64(23):17436-17447. doi: 10.1021/acs.jmedchem.1c01584. Epub 2021 Nov 23.

Because cancer is the second leading cause of death globally, investigation of new photosensitizers for photodynamic therapy is highly desirable. In this work, different peripherally substituted subphthalocyanines (SubPcs) with either a benzocrown moiety (CE-) or a tyrosine methyl ester...

Showing 1 to 12 of 16 entries