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Showing 1 to 12 of 18 entries
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Computational Metabolomics Operations at BioCyc.org.

Metabolites

Karp PD, Billington R, Holland TA, Kothari A, Krummenacker M, Weaver D, Latendresse M, Paley S.
PMID: 26011592
Metabolites. 2015 May 22;5(2):291-310. doi: 10.3390/metabo5020291.

BioCyc.org is a genome and metabolic pathway web portal covering 5500 organisms, including Homo sapiens, Arabidopsis thaliana, Saccharomyces cerevisiae and Escherichia coli. These organism-specific databases have undergone variable degrees of curation. The EcoCyc (Escherichia coli Encyclopedia) database is the...

Construction and completion of flux balance models from pathway databases.

Bioinformatics (Oxford, England)

Latendresse M, Krummenacker M, Trupp M, Karp PD.
PMID: 22262672
Bioinformatics. 2012 Feb 01;28(3):388-96. doi: 10.1093/bioinformatics/btr681. Epub 2012 Jan 18.

MOTIVATION: Flux balance analysis (FBA) is a well-known technique for genome-scale modeling of metabolic flux. Typically, an FBA formulation requires the accurate specification of four sets: biochemical reactions, biomass metabolites, nutrients and secreted metabolites. The development of FBA models...

A Comparison of Microbial Genome Web Portals.

Frontiers in microbiology

Karp PD, Ivanova N, Krummenacker M, Kyrpides N, Latendresse M, Midford P, Ong WK, Paley S, Seshadri R.
PMID: 30853946
Front Microbiol. 2019 Feb 22;10:208. doi: 10.3389/fmicb.2019.00208. eCollection 2019.

Microbial genome web portals have a broad range of capabilities that address a number of information-finding and analysis needs for scientists. This article compares the capabilities of the major microbial genome web portals to aid researchers in determining which...

The EcoCyc Database in 2021.

Frontiers in microbiology

Keseler IM, Gama-Castro S, Mackie A, Billington R, Bonavides-Martínez C, Caspi R, Kothari A, Krummenacker M, Midford PE, Muñiz-Rascado L, Ong WK, Paley S, Santos-Zavaleta A, Subhraveti P, Tierrafría VH, Wolfe AJ, Collado-Vides J, Paulsen IT, Karp PD.
PMID: 34394059
Front Microbiol. 2021 Jul 28;12:711077. doi: 10.3389/fmicb.2021.711077. eCollection 2021.

The EcoCyc model-organism database collects and summarizes experimental data for

Exceptional fossil assemblages confirm the existence of complex Early Triassic ecosystems during the early Spathian.

Scientific reports

Smith CPA, Laville T, Fara E, Escarguel G, Olivier N, Vennin E, Goudemand N, Bylund KG, Jenks JF, Stephen DA, Hautmann M, Charbonnier S, Krumenacker LJ, Brayard A.
PMID: 34608207
Sci Rep. 2021 Oct 04;11(1):19657. doi: 10.1038/s41598-021-99056-8.

The mass extinction characterizing the Permian/Triassic boundary (PTB; ~ 252 Ma) corresponds to a major faunal shift between the Palaeozoic and the Modern evolutionary fauna. The temporal, spatial, environmental, and ecological dynamics of the associated biotic recovery remain highly...

Prediction of Means and Variances of Crosses With Genome-Wide Marker Effects in Barley.

Frontiers in plant science

Osthushenrich T, Frisch M, Zenke-Philippi C, Jaiser H, Spiller M, Cselényi L, Krumnacker K, Boxberger S, Kopahnke D, Habekuß A, Ordon F, Herzog E.
PMID: 30627135
Front Plant Sci. 2018 Dec 21;9:1899. doi: 10.3389/fpls.2018.01899. eCollection 2018.

No abstract available.

The BioCyc collection of microbial genomes and metabolic pathways.

Briefings in bioinformatics

Karp PD, Billington R, Caspi R, Fulcher CA, Latendresse M, Kothari A, Keseler IM, Krummenacker M, Midford PE, Ong Q, Ong WK, Paley SM, Subhraveti P.
PMID: 29447345
Brief Bioinform. 2019 Jul 19;20(4):1085-1093. doi: 10.1093/bib/bbx085.

BioCyc.org is a microbial genome Web portal that combines thousands of genomes with additional information inferred by computer programs, imported from other databases and curated from the biomedical literature by biologist curators. BioCyc also provides an extensive range of...

The EcoCyc Database in 2021.

Frontiers in microbiology

Keseler IM, Gama-Castro S, Mackie A, Billington R, Bonavides-Martínez C, Caspi R, Kothari A, Krummenacker M, Midford PE, Muñiz-Rascado L, Ong WK, Paley S, Santos-Zavaleta A, Subhraveti P, Tierrafría VH, Wolfe AJ, Collado-Vides J, Paulsen IT, Karp PD.
PMID: 34394059
Front Microbiol. 2021 Jul 28;12:711077. doi: 10.3389/fmicb.2021.711077. eCollection 2021.

The EcoCyc model-organism database collects and summarizes experimental data for

Isolated extratesticular hematoma from intraoperative positioning during lumbar spinal surgery.

Radiology case reports

Qi-Huang S, Danilenko A, Watson C, Krumenacker J.
PMID: 34630811
Radiol Case Rep. 2021 Oct 02;16(12):3746-3750. doi: 10.1016/j.radcr.2021.09.011. eCollection 2021 Dec.

Scrotal injury is present in less than 1% of all trauma-related injuries. Traumatic injuries of the scrotum are most commonly seen in penetrating or blunt injury but may also occur after iatrogenic causes such as in the intraoperative setting....

Lack of standardisation in interpretation and reporting of autoantibody assays: a survey analysis of Australasian laboratories with focus on line immunoassays.

Pathology

Krummenacher M, Lee FJ, Wienholt L, Hissaria P.
PMID: 33994175
Pathology. 2021 Dec;53(7):883-888. doi: 10.1016/j.pathol.2021.01.018. Epub 2021 May 14.

Autoantibody assays are reported in a variety of formats. Results only slightly above established cut-offs provide lower likelihood ratios; therefore, their clinical significance may be more uncertain, which is not readily communicated with dichotomous qualitative reporting. Line immunoassays (LIA)...

Pathway Tools Visualization of Organism-Scale Metabolic Networks.

Metabolites

Paley S, Billington R, Herson J, Krummenacker M, Karp PD.
PMID: 33499002
Metabolites. 2021 Jan 22;11(2). doi: 10.3390/metabo11020064.

Metabolomics, synthetic biology, and microbiome research demand information about organism-scale metabolic networks. The convergence of genome sequencing and computational inference of metabolic networks has enabled great progress toward satisfying that demand by generating metabolic reconstructions from the genomes of...

Exceptional fossil assemblages confirm the existence of complex Early Triassic ecosystems during the early Spathian.

Scientific reports

Smith CPA, Laville T, Fara E, Escarguel G, Olivier N, Vennin E, Goudemand N, Bylund KG, Jenks JF, Stephen DA, Hautmann M, Charbonnier S, Krumenacker LJ, Brayard A.
PMID: 34608207
Sci Rep. 2021 Oct 04;11(1):19657. doi: 10.1038/s41598-021-99056-8.

The mass extinction characterizing the Permian/Triassic boundary (PTB; ~ 252 Ma) corresponds to a major faunal shift between the Palaeozoic and the Modern evolutionary fauna. The temporal, spatial, environmental, and ecological dynamics of the associated biotic recovery remain highly...

Showing 1 to 12 of 18 entries