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The Nevada Vital Aging Initiative: a private-public partnership to study early predictors of dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Thal L, Kuller L, Bowman K, Breitner J, Evans D, Farrer L, Frank R, Khachaturian AS, Khachaturian ZS, Kukull W, Nieto J, Petersen R, Sager M, Scherr P, Bain LJ.
PMID: 19595919
Alzheimers Dement. 2007 Jan;3(1):62-7. doi: 10.1016/j.jalz.2006.11.002.

No abstract available.

Cite
Thal L, Kuller L, Bowman K, et al. The Nevada Vital Aging Initiative: a private-public partnership to study early predictors of dementia. Alzheimers Dement. 2007;3(1):62-7doi: 10.1016/j.jalz.2006.11.002.
Thal, L., Kuller, L., Bowman, K., Breitner, J., Evans, D., Farrer, L., Frank, R., Khachaturian, A. S., Khachaturian, Z. S., Kukull, W., Nieto, J., Petersen, R., Sager, M., Scherr, P., & Bain, L. J. (2007). The Nevada Vital Aging Initiative: a private-public partnership to study early predictors of dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association, 3(1), 62-7. https://doi.org/10.1016/j.jalz.2006.11.002
Thal, Leon, et al. "The Nevada Vital Aging Initiative: a private-public partnership to study early predictors of dementia." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. 3,1 (2007): 62-7. doi: https://doi.org/10.1016/j.jalz.2006.11.002
Thal L, Kuller L, Bowman K, Breitner J, Evans D, Farrer L, Frank R, Khachaturian AS, Khachaturian ZS, Kukull W, Nieto J, Petersen R, Sager M, Scherr P, Bain LJ. The Nevada Vital Aging Initiative: a private-public partnership to study early predictors of dementia. Alzheimers Dement. 2007 Jan;3(1):62-7. doi: 10.1016/j.jalz.2006.11.002. PMID: 19595919.
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Abstracts from Hydrocephalus 2016.

Fluids and barriers of the CNS

Adam A, Robison J, Lu J, Jose R, Badran N, Vivas-Buitrago T, Rigamonti D, Sattar A, Omoush O, Hammad M, Dawood M, Maghaslah M, Belcher T, Carson K, Hoffberger J, Jusué Torres I, Foley S, Yasar S, Thai QA, Wemmer J, Klinge P, Al-Mutawa L, Al-Ghamdi H, Carson KA, Asgari M, de Zélicourt D, Kurtcuoglu V, Garnotel S, Salmon S, Balédent O, Lokossou A, Page G, Balardy L, Czosnyka Z, Payoux P, Schmidt EA, Zitoun M, Sevestre MA, Alperin N, Baudracco I, Craven C, Matloob S, Thompson S, Haylock Vize P, Thorne L, Watkins LD, Toma AK, Bechter K, Pong AC, Jugé L, Bilston LE, Cheng S, Bradley W, Hakim F, Ramón JF, Cárdenas MF, Davidson JS, García C, González D, Bermúdez S, Useche N, Mejía JA, Mayorga P, Cruz F, Martinez C, Matiz MC, Vallejo M, Ghotme K, Soto HA, Riveros D, Buitrago A, Mora M, Murcia L, Bermudez S, Cohen D, Dasgupta D, Curtis C, Domínguez L, Remolina AJ, Grijalba MA, Whitehouse KJ, Edwards RJ, Eleftheriou A, Lundin F, Fountas KN, Kapsalaki EZ, Smisson HF, Robinson JS, Fritsch MJ, Arouk W, Garzon M, Kang M, Sandhu K, Baghawatti D, Aquilina K, James G, Thompson D, Gehlen M, Schmid Daners M, Eklund A, Malm J, Gomez D, Guerra M, Jara M, Flores M, Vío K, Moreno I, Rodríguez S, Ortega E, Rodríguez EM, McAllister JP, Guerra MM, Morales DM, Sival D, Jimenez A, Limbrick DD, Ishikawa M, Yamada S, Yamamoto K, Junkkari A, Häyrinen A, Rauramaa T, Sintonen H, Nerg O, Koivisto AM, Roine RP, Viinamäki H, Soininen H, Luikku A, Jääskeläinen JE, Leinonen V, Kehler U, Lilja-Lund O, Kockum K, Larsson EM, Riklund K, Söderström L, Hellström P, Laurell K, Kojoukhova M, Sutela A, Vanninen R, Vanha KI, Timonen M, Rummukainen J, Korhonen V, Helisalmi S, Solje E, Remes AM, Huovinen J, Paananen J, Hiltunen M, Kurki M, Martin B, Loth F, Luciano M, Luikku AJ, Hall A, Herukka SK, Mattila J, Lötjönen J, Alafuzoff I, Jurjević I, Miyajima M, Nakajima M, Murai H, Shin T, Kawaguchi D, Akiba C, Ogino I, Karagiozov K, Arai H, Reis RC, Teixeira MJ, Valêncio CG, da Vigua D, Almeida-Lopes L, Mancini MW, Pinto FCG, Maykot RH, Calia G, Tornai J, Silvestre SSS, Mendes G, Sousa V, Bezerra B, Dutra P, Modesto P, Oliveira MF, Petitto CE, Pulhorn H, Chandran A, McMahon C, Rao AS, Jumaly M, Solomon D, Moghekar A, Relkin N, Hamilton M, Katzen H, Williams M, Bach T, Zuspan S, Holubkov R, Rigamonti A, Clemens G, Sharkey P, Sanyal A, Sankey E, Rigamonti K, Naqvi S, Hung A, Schmidt E, Ory-Magne F, Gantet P, Guenego A, Januel AC, Tall P, Fabre N, Mahieu L, Cognard C, Gray L, Buttner-Ennever JA, Takagi K, Onouchi K, Thompson SD, Thorne LD, Tully HM, Wenger TL, Kukull WA, Doherty D, Dobyns WB, Moran D, Vakili S, Patel MA, Elder B, Goodwin CR, Crawford JA, Pletnikov MV, Xu J, Blitz A, Herzka DA, Guerrero-Cazares H, Quiñones-Hinojosa A, Mori S, Saavedra P, Treviño H, Maitani K, Ziai WC, Eslami V, Nekoovaght-Tak S, Dlugash R, Yenokyan G, McBee N, Hanley DF.
PMID: 28929972
Fluids Barriers CNS. 2017 Jun 07;14:15. doi: 10.1186/s12987-017-0054-5.

No abstract available.

Cite
Adam A, Robison J, Lu J, et al. Abstracts from Hydrocephalus 2016. Fluids Barriers CNS. 2017;14:15doi: 10.1186/s12987-017-0054-5.
Adam, A., Robison, J., Lu, J., Jose, R., Badran, N., Vivas-Buitrago, T., Rigamonti, D., Sattar, A., Omoush, O., Hammad, M., Dawood, M., Maghaslah, M., Belcher, T., Carson, K., Hoffberger, J., Jusué Torres, I., Foley, S., Yasar, S., Thai, Q. A., Wemmer, J., Klinge, P., Al-Mutawa, L., Al-Ghamdi, H., Carson, K. A., Asgari, M., de Zélicourt, D., Kurtcuoglu, V., Garnotel, S., Salmon, S., Balédent, O., Lokossou, A., Page, G., Balardy, L., Czosnyka, Z., Payoux, P., Schmidt, E. A., Zitoun, M., Sevestre, M. A., Alperin, N., Baudracco, I., Craven, C., Matloob, S., Thompson, S., Haylock Vize, P., Thorne, L., Watkins, L. D., Toma, A. K., Bechter, K., Pong, A. C., Jugé, L., Bilston, L. E., Cheng, S., Bradley, W., Hakim, F., Ramón, J. F., Cárdenas, M. F., Davidson, J. S., García, C., González, D., Bermúdez, S., Useche, N., Mejía, J. A., Mayorga, P., Cruz, F., Martinez, C., Matiz, M. C., Vallejo, M., Ghotme, K., Soto, H. A., Riveros, D., Buitrago, A., Mora, M., Murcia, L., Bermudez, S., Cohen, D., Dasgupta, D., Curtis, C., Domínguez, L., Remolina, A. J., Grijalba, M. A., Whitehouse, K. J., Edwards, R. J., Eleftheriou, A., Lundin, F., Fountas, K. N., Kapsalaki, E. Z., Smisson, H. F., Robinson, J. S., Fritsch, M. J., Arouk, W., Garzon, M., Kang, M., Sandhu, K., Baghawatti, D., Aquilina, K., James, G., Thompson, D., Gehlen, M., Schmid Daners, M., Eklund, A., Malm, J., Gomez, D., Guerra, M., Jara, M., Flores, M., Vío, K., Moreno, I., Rodríguez, S., Ortega, E., Rodríguez, E. M., McAllister, J. P., Guerra, M. M., Morales, D. M., Sival, D., Jimenez, A., Limbrick, D. D., Ishikawa, M., Yamada, S., Yamamoto, K., Junkkari, A., Häyrinen, A., Rauramaa, T., Sintonen, H., Nerg, O., Koivisto, A. M., Roine, R. P., Viinamäki, H., Soininen, H., Luikku, A., Jääskeläinen, J. E., Leinonen, V., Kehler, U., Lilja-Lund, O., Kockum, K., Larsson, E. M., Riklund, K., Söderström, L., Hellström, P., Laurell, K., Kojoukhova, M., Sutela, A., Vanninen, R., Vanha, K. I., Timonen, M., Rummukainen, J., Korhonen, V., Helisalmi, S., Solje, E., Remes, A. M., Huovinen, J., Paananen, J., Hiltunen, M., Kurki, M., Martin, B., Loth, F., Luciano, M., Luikku, A. J., Hall, A., Herukka, S. K., Mattila, J., Lötjönen, J., Alafuzoff, I., Jurjević, I., Miyajima, M., Nakajima, M., Murai, H., Shin, T., Kawaguchi, D., Akiba, C., Ogino, I., Karagiozov, K., Arai, H., Reis, R. C., Teixeira, M. J., Valêncio, C. G., da Vigua, D., Almeida-Lopes, L., Mancini, M. W., Pinto, F. C. G., Maykot, R. H., Calia, G., Tornai, J., Silvestre, S. S. S., Mendes, G., Sousa, V., Bezerra, B., Dutra, P., Modesto, P., Oliveira, M. F., Petitto, C. E., Pulhorn, H., Chandran, A., McMahon, C., Rao, A. S., Jumaly, M., Solomon, D., Moghekar, A., Relkin, N., Hamilton, M., Katzen, H., Williams, M., Bach, T., Zuspan, S., Holubkov, R., Rigamonti, A., Clemens, G., Sharkey, P., Sanyal, A., Sankey, E., Rigamonti, K., Naqvi, S., Hung, A., Schmidt, E., Ory-Magne, F., Gantet, P., Guenego, A., Januel, A. C., Tall, P., Fabre, N., Mahieu, L., Cognard, C., Gray, L., Buttner-Ennever, J. A., Takagi, K., Onouchi, K., Thompson, S. D., Thorne, L. D., Tully, H. M., Wenger, T. L., Kukull, W. A., Doherty, D., Dobyns, W. B., Moran, D., Vakili, S., Patel, M. A., Elder, B., Goodwin, C. R., Crawford, J. A., Pletnikov, M. V., Xu, J., Blitz, A., Herzka, D. A., Guerrero-Cazares, H., Quiñones-Hinojosa, A., Mori, S., Saavedra, P., Treviño, H., Maitani, K., Ziai, W. C., Eslami, V., Nekoovaght-Tak, S., Dlugash, R., Yenokyan, G., McBee, N., & Hanley, D. F. (2017). Abstracts from Hydrocephalus 2016. Fluids and barriers of the CNS, 1415. https://doi.org/10.1186/s12987-017-0054-5
Adam, A, et al. "Abstracts from Hydrocephalus 2016." Fluids and barriers of the CNS vol. 14 (2017): 15. doi: https://doi.org/10.1186/s12987-017-0054-5
Adam A, Robison J, Lu J, Jose R, Badran N, Vivas-Buitrago T, Rigamonti D, Sattar A, Omoush O, Hammad M, Dawood M, Maghaslah M, Belcher T, Carson K, Hoffberger J, Jusué Torres I, Foley S, Yasar S, Thai QA, Wemmer J, Klinge P, Al-Mutawa L, Al-Ghamdi H, Carson KA, Asgari M, de Zélicourt D, Kurtcuoglu V, Garnotel S, Salmon S, Balédent O, Lokossou A, Page G, Balardy L, Czosnyka Z, Payoux P, Schmidt EA, Zitoun M, Sevestre MA, Alperin N, Baudracco I, Craven C, Matloob S, Thompson S, Haylock Vize P, Thorne L, Watkins LD, Toma AK, Bechter K, Pong AC, Jugé L, Bilston LE, Cheng S, Bradley W, Hakim F, Ramón JF, Cárdenas MF, Davidson JS, García C, González D, Bermúdez S, Useche N, Mejía JA, Mayorga P, Cruz F, Martinez C, Matiz MC, Vallejo M, Ghotme K, Soto HA, Riveros D, Buitrago A, Mora M, Murcia L, Bermudez S, Cohen D, Dasgupta D, Curtis C, Domínguez L, Remolina AJ, Grijalba MA, Whitehouse KJ, Edwards RJ, Eleftheriou A, Lundin F, Fountas KN, Kapsalaki EZ, Smisson HF, Robinson JS, Fritsch MJ, Arouk W, Garzon M, Kang M, Sandhu K, Baghawatti D, Aquilina K, James G, Thompson D, Gehlen M, Schmid Daners M, Eklund A, Malm J, Gomez D, Guerra M, Jara M, Flores M, Vío K, Moreno I, Rodríguez S, Ortega E, Rodríguez EM, McAllister JP, Guerra MM, Morales DM, Sival D, Jimenez A, Limbrick DD, Ishikawa M, Yamada S, Yamamoto K, Junkkari A, Häyrinen A, Rauramaa T, Sintonen H, Nerg O, Koivisto AM, Roine RP, Viinamäki H, Soininen H, Luikku A, Jääskeläinen JE, Leinonen V, Kehler U, Lilja-Lund O, Kockum K, Larsson EM, Riklund K, Söderström L, Hellström P, Laurell K, Kojoukhova M, Sutela A, Vanninen R, Vanha KI, Timonen M, Rummukainen J, Korhonen V, Helisalmi S, Solje E, Remes AM, Huovinen J, Paananen J, Hiltunen M, Kurki M, Martin B, Loth F, Luciano M, Luikku AJ, Hall A, Herukka SK, Mattila J, Lötjönen J, Alafuzoff I, Jurjević I, Miyajima M, Nakajima M, Murai H, Shin T, Kawaguchi D, Akiba C, Ogino I, Karagiozov K, Arai H, Reis RC, Teixeira MJ, Valêncio CG, da Vigua D, Almeida-Lopes L, Mancini MW, Pinto FCG, Maykot RH, Calia G, Tornai J, Silvestre SSS, Mendes G, Sousa V, Bezerra B, Dutra P, Modesto P, Oliveira MF, Petitto CE, Pulhorn H, Chandran A, McMahon C, Rao AS, Jumaly M, Solomon D, Moghekar A, Relkin N, Hamilton M, Katzen H, Williams M, Bach T, Zuspan S, Holubkov R, Rigamonti A, Clemens G, Sharkey P, Sanyal A, Sankey E, Rigamonti K, Naqvi S, Hung A, Schmidt E, Ory-Magne F, Gantet P, Guenego A, Januel AC, Tall P, Fabre N, Mahieu L, Cognard C, Gray L, Buttner-Ennever JA, Takagi K, Onouchi K, Thompson SD, Thorne LD, Tully HM, Wenger TL, Kukull WA, Doherty D, Dobyns WB, Moran D, Vakili S, Patel MA, Elder B, Goodwin CR, Crawford JA, Pletnikov MV, Xu J, Blitz A, Herzka DA, Guerrero-Cazares H, Quiñones-Hinojosa A, Mori S, Saavedra P, Treviño H, Maitani K, Ziai WC, Eslami V, Nekoovaght-Tak S, Dlugash R, Yenokyan G, McBee N, Hanley DF. Abstracts from Hydrocephalus 2016. Fluids Barriers CNS. 2017 Jun 07;14:15. doi: 10.1186/s12987-017-0054-5. PMID: 28929972; PMCID: PMC5471936.
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Whipple's disease: a fatal mimic.

Autopsy & case reports

Kukull B, Mahlow J, Hale G, Perry LJ.
PMID: 34277495
Autops Case Rep. 2021 Jan 28;11:e2020237. doi: 10.4322/acr.2020.237. eCollection 2021.

Whipple's Disease, a rare diagnosis caused by the slow-growing bacterium

Cite
Kukull B, Mahlow J, Hale G, et al. Whipple's disease: a fatal mimic. Autops Case Rep. 2021;11:e2020237doi: 10.4322/acr.2020.237.
Kukull, B., Mahlow, J., Hale, G., & Perry, L. J. (2021). Whipple's disease: a fatal mimic. Autopsy & case reports, 11e2020237. https://doi.org/10.4322/acr.2020.237
Kukull, Benjamin, et al. "Whipple's disease: a fatal mimic." Autopsy & case reports vol. 11 (2021): e2020237. doi: https://doi.org/10.4322/acr.2020.237
Kukull B, Mahlow J, Hale G, Perry LJ. Whipple's disease: a fatal mimic. Autops Case Rep. 2021 Jan 28;11:e2020237. doi: 10.4322/acr.2020.237. eCollection 2021. PMID: 34277495; PMCID: PMC8101681.
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Differences in Symptomatic Presentation and Cognitive Performance Among Participants With LATE-NC Compared to FTLD-TDP.

Journal of neuropathology and experimental neurology

Teylan MA, Mock C, Gauthreaux K, Culhane JE, Jicha G, Chen YC, Chan KCG, Kukull WA, Nelson PT, Katsumata Y.
PMID: 34597386
J Neuropathol Exp Neurol. 2021 Oct 01; doi: 10.1093/jnen/nlab098. Epub 2021 Oct 01.

Transactive response DNA-binding protein 43 kDa (TDP-43) is aberrantly aggregated and phosphorylated in frontotemporal lobar degeneration of the TDP-43 type (FTLD-TDP), and in limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC). We examined data from the National Alzheimer's Coordinating Center...

Cite
Teylan MA, Mock C, Gauthreaux K, et al. Differences in Symptomatic Presentation and Cognitive Performance Among Participants With LATE-NC Compared to FTLD-TDP. J Neuropathol Exp Neurol. 2021;doi: 10.1093/jnen/nlab098.
Teylan, M. A., Mock, C., Gauthreaux, K., Culhane, J. E., Jicha, G., Chen, Y. C., Chan, K. C. G., Kukull, W. A., Nelson, P. T., & Katsumata, Y. (2021). Differences in Symptomatic Presentation and Cognitive Performance Among Participants With LATE-NC Compared to FTLD-TDP. Journal of neuropathology and experimental neurology, . https://doi.org/10.1093/jnen/nlab098
Teylan, Merilee A, et al. "Differences in Symptomatic Presentation and Cognitive Performance Among Participants With LATE-NC Compared to FTLD-TDP." Journal of neuropathology and experimental neurology vol. (2021). doi: https://doi.org/10.1093/jnen/nlab098
Teylan MA, Mock C, Gauthreaux K, Culhane JE, Jicha G, Chen YC, Chan KCG, Kukull WA, Nelson PT, Katsumata Y. Differences in Symptomatic Presentation and Cognitive Performance Among Participants With LATE-NC Compared to FTLD-TDP. J Neuropathol Exp Neurol. 2021 Oct 01; doi: 10.1093/jnen/nlab098. Epub 2021 Oct 01. PMID: 34597386.
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Enhancing access to innovative cancer drugs: cross-sector consensus on a way forward to benefit patients.

Drug discovery today

Hoey R, Sharpe E, Kukula A, Workman P.
PMID: 34954130
Drug Discov Today. 2021 Dec 22; doi: 10.1016/j.drudis.2021.12.015. Epub 2021 Dec 22.

New discoveries and technologies are driving major advances in our understanding of cancer and underpinning a new era of precision medicine and immunotherapy. However, advances in treatment have been uneven: whereas survival rates for some common cancers are improving...

Cite
Hoey R, Sharpe E, Kukula A, et al. Enhancing access to innovative cancer drugs: cross-sector consensus on a way forward to benefit patients. Drug Discov Today. 2021;doi: 10.1016/j.drudis.2021.12.015.
Hoey, R., Sharpe, E., Kukula, A., & Workman, P. (2021). Enhancing access to innovative cancer drugs: cross-sector consensus on a way forward to benefit patients. Drug discovery today, . https://doi.org/10.1016/j.drudis.2021.12.015
Hoey, Richard, et al. "Enhancing access to innovative cancer drugs: cross-sector consensus on a way forward to benefit patients." Drug discovery today vol. (2021). doi: https://doi.org/10.1016/j.drudis.2021.12.015
Hoey R, Sharpe E, Kukula A, Workman P. Enhancing access to innovative cancer drugs: cross-sector consensus on a way forward to benefit patients. Drug Discov Today. 2021 Dec 22; doi: 10.1016/j.drudis.2021.12.015. Epub 2021 Dec 22. PMID: 34954130.
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Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Nature genetics

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y, Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, O'Donovan MC, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA.
PMID: 31417202
Nat Genet. 2019 Sep;51(9):1423-1424. doi: 10.1038/s41588-019-0495-7.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Cite
Kunkle BW, Grenier-Boley B, Sims R, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019;51(9):1423-1424doi: 10.1038/s41588-019-0495-7.
Kunkle, B. W., Grenier-Boley, B., Sims, R., Bis, J. C., Damotte, V., Naj, A. C., Boland, A., Vronskaya, M., van der Lee, S. J., Amlie-Wolf, A., Bellenguez, C., Frizatti, A., Chouraki, V., Martin, E. R., Sleegers, K., Badarinarayan, N., Jakobsdottir, J., Hamilton-Nelson, K. L., Moreno-Grau, S., Olaso, R., Raybould, R., Chen, Y., Kuzma, A. B., Hiltunen, M., Morgan, T., Ahmad, S., Vardarajan, B. N., Epelbaum, J., Hoffmann, P., Boada, M., Beecham, G. W., Garnier, J. G., Harold, D., Fitzpatrick, A. L., Valladares, O., Moutet, M. L., Gerrish, A., Smith, A. V., Qu, L., Bacq, D., Denning, N., Jian, X., Zhao, Y., Del Zompo, M., Fox, N. C., Choi, S. H., Mateo, I., Hughes, J. T., Adams, H. H., Malamon, J., Sanchez-Garcia, F., Patel, Y., Brody, J. A., Dombroski, B. A., Naranjo, M. C. D., Daniilidou, M., Eiriksdottir, G., Mukherjee, S., Wallon, D., Uphill, J., Aspelund, T., Cantwell, L. B., Garzia, F., Galimberti, D., Hofer, E., Butkiewicz, M., Fin, B., Scarpini, E., Sarnowski, C., Bush, W. S., Meslage, S., Kornhuber, J., White, C. C., Song, Y., Barber, R. C., Engelborghs, S., Sordon, S., Voijnovic, D., Adams, P. M., Vandenberghe, R., Mayhaus, M., Cupples, L. A., Albert, M. S., De Deyn, P. P., Gu, W., Himali, J. J., Beekly, D., Squassina, A., Hartmann, A. M., Orellana, A., Blacker, D., Rodriguez-Rodriguez, E., Lovestone, S., Garcia, M. E., Doody, R. S., Munoz-Fernadez, C., Sussams, R., Lin, H., Fairchild, T. J., Benito, Y. A., Holmes, C., Karamujić-Čomić, H., Frosch, M. P., Thonberg, H., Maier, W., Roshchupkin, G., Ghetti, B., Giedraitis, V., Kawalia, A., Li, S., Huebinger, R. M., Kilander, L., Moebus, S., Hernández, I., Kamboh, M. I., Brundin, R., Turton, J., Yang, Q., Katz, M. J., Concari, L., Lord, J., Beiser, A. S., Keene, C. D., Helisalmi, S., Kloszewska, I., Kukull, W. A., Koivisto, A. M., Lynch, A., Tarraga, L., Larson, E. B., Haapasalo, A., Lawlor, B., Mosley, T. H., Lipton, R. B., Solfrizzi, V., Gill, M., Longstreth, W. T., Montine, T. J., Frisardi, V., Diez-Fairen, M., Rivadeneira, F., Petersen, R. C., Deramecourt, V., Alvarez, I., Salani, F., Ciaramella, A., Boerwinkle, E., Reiman, E. M., Fievet, N., Rotter, J. I., Reisch, J. S., Hanon, O., Cupidi, C., Uitterlinden, A. G. A., Royall, D. R., Dufouil, C., Maletta, R. G., de Rojas, I., Sano, M., Brice, A., Cecchetti, R., George-Hyslop, P. S., Ritchie, K., Tsolaki, M., Tsuang, D. W., Dubois, B., Craig, D., Wu, C. K., Soininen, H., Avramidou, D., Albin, R. L., Fratiglioni, L., Germanou, A., Apostolova, L. G., Keller, L., Koutroumani, M., Arnold, S. E., Panza, F., Gkatzima, O., Asthana, S., Hannequin, D., Whitehead, P., Atwood, C. S., Caffarra, P., Hampel, H., Quintela, I., Carracedo, �. �., Lannfelt, L., Rubinsztein, D. C., Barnes, L. L., Pasquier, F., Frölich, L., Barral, S., McGuinness, B., Beach, T. G., Johnston, J. A., Becker, J. T., Passmore, P., Bigio, E. H., Schott, J. M., Bird, T. D., Warren, J. D., Boeve, B. F., Lupton, M. K., Bowen, J. D., Proitsi, P., Boxer, A., Powell, J. F., Burke, J. R., Kauwe, J. S. K., Burns, J. M., Mancuso, M., Buxbaum, J. D., Bonuccelli, U., Cairns, N. J., McQuillin, A., Cao, C., Livingston, G., Carlson, C. S., Bass, N. J., Carlsson, C. M., Hardy, J., Carney, R. M., Bras, J., Carrasquillo, M. M., Guerreiro, R., Allen, M., Chui, H. C., Fisher, E., Masullo, C., Crocco, E. A., DeCarli, C., Bisceglio, G., Dick, M., Ma, L., Duara, R., Graff-Radford, N. R., Evans, D. A., Hodges, A., Faber, K. M., Scherer, M., Fallon, K. B., Riemenschneider, M., Fardo, D. W., Heun, R., Farlow, M. R., Kölsch, H., Ferris, S., Leber, M., Foroud, T. M., Heuser, I., Galasko, D. R., Giegling, I., Gearing, M., Hüll, M., Geschwind, D. H., Gilbert, J. R., Morris, J., Green, R. C., Mayo, K., Growdon, J. H., Feulner, T., Hamilton, R. L., Harrell, L. E., Drichel, D., Honig, L. S., Cushion, T. D., Huentelman, M. J., Hollingworth, P., Hulette, C. M., Hyman, B. T., Marshall, R., Jarvik, G. P., Meggy, A., Abner, E., Menzies, G. E., Jin, L. W., Leonenko, G., Real, L. M., Jun, G. R., Baldwin, C. T., Grozeva, D., Karydas, A., Russo, G., Kaye, J. A., Kim, R., Jessen, F., Kowall, N. W., Vellas, B., Kramer, J. H., Vardy, E., LaFerla, F. M., Jöckel, K. H., Lah, J. J., Dichgans, M., Leverenz, J. B., Mann, D., Levey, A. I., Pickering-Brown, S., Lieberman, A. P., Klopp, N., Lunetta, K. L., Wichmann, H. E., Lyketsos, C. G., Morgan, K., Marson, D. C., Brown, K., Martiniuk, F., Medway, C., Mash, D. C., Nöthen, M. M., Masliah, E., Hooper, N. M., McCormick, W. C., Daniele, A., McCurry, S. M., Bayer, A., McDavid, A. N., Gallacher, J., McKee, A. C., van den Bussche, H., Mesulam, M., Brayne, C., Miller, B. L., Riedel-Heller, S., Miller, C. A., Miller, J. W., Al-Chalabi, A., Morris, J. C., Shaw, C. E., Myers, A. J., Wiltfang, J., O'Bryant, S., Olichney, J. M., Alvarez, V., Parisi, J. E., Singleton, A. B., Paulson, H. L., Collinge, J., Perry, W. R., Mead, S., Peskind, E., Cribbs, D. H., Rossor, M., Pierce, A., Ryan, N. S., Poon, W. W., Nacmias, B., Potter, H., Sorbi, S., Quinn, J. F., Sacchinelli, E., Raj, A., Spalletta, G., Raskind, M., Caltagirone, C., Bossù, P., Orfei, M. D., Reisberg, B., Clarke, R., Reitz, C., Smith, A. D., Ringman, J. M., Warden, D., Roberson, E. D., Wilcock, G., Rogaeva, E., Bruni, A. C., Rosen, H. J., Gallo, M., Rosenberg, R. N., Ben-Shlomo, Y., Sager, M. A., Mecocci, P., Saykin, A. J., Pastor, P., Cuccaro, M. L., Vance, J. M., Schneider, J. A., Schneider, L. S., Slifer, S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tang, M., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Saba, Y., Pilotto, A., Bullido, M. J., Peters, O., Crane, P. K., Bennett, D., Bosco, P., Coto, E., Boccardi, V., De Jager, P. L., Lleo, A., Warner, N., Lopez, O. L., Ingelsson, M., Deloukas, P., Cruchaga, C., Graff, C., Gwilliam, R., Fornage, M., Goate, A. M., Sanchez-Juan, P., Kehoe, P. G., Amin, N., Ertekin-Taner, N., Berr, C., Debette, S., Love, S., Launer, L. J., Younkin, S. G., Dartigues, J. F., Corcoran, C., Ikram, M. A., Dickson, D. W., Nicolas, G., Campion, D., Tschanz, J., Schmidt, H., Hakonarson, H., Clarimon, J., Munger, R., Schmidt, R., Farrer, L. A., Van Broeckhoven, C., O'Donovan, M. C., DeStefano, A. L., Jones, L., Haines, J. L., Deleuze, J. F., Owen, M. J., Gudnason, V., Mayeux, R., Escott-Price, V., Psaty, B. M., Ramirez, A., Wang, L. S., Ruiz, A., van Duijn, C. M., Holmans, P. A., Seshadri, S., Williams, J., Amouyel, P., Schellenberg, G. D., Lambert, J. C., & Pericak-Vance, M. A. (2019). Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature genetics, 51(9), 1423-1424. https://doi.org/10.1038/s41588-019-0495-7
Kunkle, Brian W, et al. "Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing." Nature genetics vol. 51,9 (2019): 1423-1424. doi: https://doi.org/10.1038/s41588-019-0495-7
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujić-Čomić H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, Quinn JF, Sacchinelli E, Raj A, Spalletta G, Raskind M, Caltagirone C, Bossù P, Orfei MD, Reisberg B, Clarke R, Reitz C, Smith AD, Ringman JM, Warden D, Roberson ED, Wilcock G, Rogaeva E, Bruni AC, Rosen HJ, Gallo M, Rosenberg RN, Ben-Shlomo Y, Sager MA, Mecocci P, Saykin AJ, Pastor P, Cuccaro ML, Vance JM, Schneider JA, Schneider LS, Slifer S, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tang M, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Saba Y, Pilotto A, Bullido MJ, Peters O, Crane PK, Bennett D, Bosco P, Coto E, Boccardi V, De Jager PL, Lleo A, Warner N, Lopez OL, Ingelsson M, Deloukas P, Cruchaga C, Graff C, Gwilliam R, Fornage M, Goate AM, Sanchez-Juan P, Kehoe PG, Amin N, Ertekin-Taner N, Berr C, Debette S, Love S, Launer LJ, Younkin SG, Dartigues JF, Corcoran C, Ikram MA, Dickson DW, Nicolas G, Campion D, Tschanz J, Schmidt H, Hakonarson H, Clarimon J, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, O'Donovan MC, DeStefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux R, Escott-Price V, Psaty BM, Ramirez A, Wang LS, Ruiz A, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nat Genet. 2019 Sep;51(9):1423-1424. doi: 10.1038/s41588-019-0495-7. PMID: 31417202; PMCID: PMC7265117.
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A Novel Study Paradigm for Long-term Prevention Trials in Alzheimer Disease: The Placebo Group Simulation Approach (PGSA): Application to MCI data from the NACC database.

The journal of prevention of Alzheimer's disease

Berres M, Kukull WA, Miserez AR, Monsch AU, Monsell SE, Spiegel R.
PMID: 25530953
J Prev Alzheimers Dis. 2014;1(2):99-109.

INTRODUCTION: The PGSA (Placebo Group Simulation Approach) aims at avoiding problems of sample representativeness and ethical issues typical of placebo-controlled secondary prevention trials with MCI patients. The PGSA uses mathematical modeling to forecast the distribution of quantified outcomes of...

Cite
Berres M, Kukull WA, Miserez AR, et al. A Novel Study Paradigm for Long-term Prevention Trials in Alzheimer Disease: The Placebo Group Simulation Approach (PGSA): Application to MCI data from the NACC database. J Prev Alzheimers Dis. 2014;1(2):99-109
Berres, M., Kukull, W. A., Miserez, A. R., Monsch, A. U., Monsell, S. E., & Spiegel, R. (2014). A Novel Study Paradigm for Long-term Prevention Trials in Alzheimer Disease: The Placebo Group Simulation Approach (PGSA): Application to MCI data from the NACC database. The journal of prevention of Alzheimer's disease, 1(2), 99-109.
Berres, M, et al. "A Novel Study Paradigm for Long-term Prevention Trials in Alzheimer Disease: The Placebo Group Simulation Approach (PGSA): Application to MCI data from the NACC database." The journal of prevention of Alzheimer's disease vol. 1,2 (2014): 99-109.
Berres M, Kukull WA, Miserez AR, Monsch AU, Monsell SE, Spiegel R. A Novel Study Paradigm for Long-term Prevention Trials in Alzheimer Disease: The Placebo Group Simulation Approach (PGSA): Application to MCI data from the NACC database. J Prev Alzheimers Dis. 2014;1(2):99-109. PMID: 25530953; PMCID: PMC4268776.
Copy Download .nbib Format: NLM
Variants associated with Gaucher disease in multiple system atrophy.

Annals of clinical and translational neurology

Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Takashima H, Kikuchi A, Aoki M, Ishiura H, Yasuda T, Date H, Ahsan B, Iwata A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S.
PMID: 25909086
Ann Clin Transl Neurol. 2015 Apr;2(4):417-26. doi: 10.1002/acn3.185. Epub 2015 Feb 28.

OBJECTIVE: Glucocerebrosidase gene (GBA) variants that cause Gaucher disease are associated with Parkinson disease (PD) and dementia with Lewy bodies (DLB). To investigate the role of GBA variants in multiple system atrophy (MSA), we analyzed GBA variants in a...

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Mitsui J, Matsukawa T, Sasaki H, et al. Variants associated with Gaucher disease in multiple system atrophy. Ann Clin Transl Neurol. 2015;2(4):417-26doi: 10.1002/acn3.185.
Mitsui, J., Matsukawa, T., Sasaki, H., Yabe, I., Matsushima, M., Dürr, A., Brice, A., Takashima, H., Kikuchi, A., Aoki, M., Ishiura, H., Yasuda, T., Date, H., Ahsan, B., Iwata, A., Goto, J., Ichikawa, Y., Nakahara, Y., Momose, Y., Takahashi, Y., Hara, K., Kakita, A., Yamada, M., Takahashi, H., Onodera, O., Nishizawa, M., Watanabe, H., Ito, M., Sobue, G., Ishikawa, K., Mizusawa, H., Kanai, K., Hattori, T., Kuwabara, S., Arai, K., Koyano, S., Kuroiwa, Y., Hasegawa, K., Yuasa, T., Yasui, K., Nakashima, K., Ito, H., Izumi, Y., Kaji, R., Kato, T., Kusunoki, S., Osaki, Y., Horiuchi, M., Kondo, T., Murayama, S., Hattori, N., Yamamoto, M., Murata, M., Satake, W., Toda, T., Filla, A., Klockgether, T., Wüllner, U., Nicholson, G., Gilman, S., Tanner, C. M., Kukull, W. A., Stern, M. B., Lee, V. M., Trojanowski, J. Q., Masliah, E., Low, P. A., Sandroni, P., Ozelius, L. J., Foroud, T., & Tsuji, S. (2015). Variants associated with Gaucher disease in multiple system atrophy. Annals of clinical and translational neurology, 2(4), 417-26. https://doi.org/10.1002/acn3.185
Mitsui, Jun, et al. "Variants associated with Gaucher disease in multiple system atrophy." Annals of clinical and translational neurology vol. 2,4 (2015): 417-26. doi: https://doi.org/10.1002/acn3.185
Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Takashima H, Kikuchi A, Aoki M, Ishiura H, Yasuda T, Date H, Ahsan B, Iwata A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S. Variants associated with Gaucher disease in multiple system atrophy. Ann Clin Transl Neurol. 2015 Apr;2(4):417-26. doi: 10.1002/acn3.185. Epub 2015 Feb 28. PMID: 25909086; PMCID: PMC4402086.
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BREAST CANCER HISTOPATHOLOGY IMAGE ANALYSIS PIPELINE FOR TUMOR PURITY ESTIMATION.

Proceedings. IEEE International Symposium on Biomedical Imaging

Azimi V, Chang YH, Thibault G, Smith J, Tsujikawa T, Kukull B, Jensen B, Corless C, Margolin A, Gray JW.
PMID: 30364881
Proc IEEE Int Symp Biomed Imaging. 2017 Apr;2017:1137-1140. doi: 10.1109/ISBI.2017.7950717. Epub 2017 Jun 19.

The translation of genomic sequencing technology to the clinic has greatly advanced personalized medicine. However, the presence of normal cells in tumors is a confounding factor in genome sequence analysis. Tumor purity, or the percentage of cancerous cells in...

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Azimi V, Chang YH, Thibault G, et al. BREAST CANCER HISTOPATHOLOGY IMAGE ANALYSIS PIPELINE FOR TUMOR PURITY ESTIMATION. Proc IEEE Int Symp Biomed Imaging. 2017;2017:1137-1140doi: 10.1109/ISBI.2017.7950717.
Azimi, V., Chang, Y. H., Thibault, G., Smith, J., Tsujikawa, T., Kukull, B., Jensen, B., Corless, C., Margolin, A., & Gray, J. W. (2017). BREAST CANCER HISTOPATHOLOGY IMAGE ANALYSIS PIPELINE FOR TUMOR PURITY ESTIMATION. Proceedings. IEEE International Symposium on Biomedical Imaging, 20171137-1140. https://doi.org/10.1109/ISBI.2017.7950717
Azimi, Vahid, et al. "BREAST CANCER HISTOPATHOLOGY IMAGE ANALYSIS PIPELINE FOR TUMOR PURITY ESTIMATION." Proceedings. IEEE International Symposium on Biomedical Imaging vol. 2017 (2017): 1137-1140. doi: https://doi.org/10.1109/ISBI.2017.7950717
Azimi V, Chang YH, Thibault G, Smith J, Tsujikawa T, Kukull B, Jensen B, Corless C, Margolin A, Gray JW. BREAST CANCER HISTOPATHOLOGY IMAGE ANALYSIS PIPELINE FOR TUMOR PURITY ESTIMATION. Proc IEEE Int Symp Biomed Imaging. 2017 Apr;2017:1137-1140. doi: 10.1109/ISBI.2017.7950717. Epub 2017 Jun 19. PMID: 30364881; PMCID: PMC6198647.
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Uniform data set language measures for bvFTD and PPA diagnosis and monitoring.

Alzheimer's & dementia (Amsterdam, Netherlands)

Staffaroni AM, Weintraub S, Rascovsky K, Rankin KP, Taylor J, Fields JA, Casaletto KB, Hillis AE, Lukic S, Gorno-Tempini ML, Heuer H, Teylan MA, Kukull WA, Miller BL, Boeve BF, Rosen HJ, Boxer AL, Kramer JH.
PMID: 33665340
Alzheimers Dement (Amst). 2021 Feb 20;13(1):e12148. doi: 10.1002/dad2.12148. eCollection 2021.

INTRODUCTION: The Frontotemporal Lobar Degeneration Module (FTLD-MOD) includes a neuropsychological battery designed to assess the clinical features of FTLD, although much is unknown about its utility. We investigated FTLD-MOD and Uniform Data Set 3.0 (UDS) language tests for differential...

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Staffaroni AM, Weintraub S, Rascovsky K, et al. Uniform data set language measures for bvFTD and PPA diagnosis and monitoring. Alzheimers Dement (Amst). 2021;13(1):e12148doi: 10.1002/dad2.12148.
Staffaroni, A. M., Weintraub, S., Rascovsky, K., Rankin, K. P., Taylor, J., Fields, J. A., Casaletto, K. B., Hillis, A. E., Lukic, S., Gorno-Tempini, M. L., Heuer, H., Teylan, M. A., Kukull, W. A., Miller, B. L., Boeve, B. F., Rosen, H. J., Boxer, A. L., & Kramer, J. H. (2021). Uniform data set language measures for bvFTD and PPA diagnosis and monitoring. Alzheimer's & dementia (Amsterdam, Netherlands), 13(1), e12148. https://doi.org/10.1002/dad2.12148
Staffaroni, Adam M, et al. "Uniform data set language measures for bvFTD and PPA diagnosis and monitoring." Alzheimer's & dementia (Amsterdam, Netherlands) vol. 13,1 (2021): e12148. doi: https://doi.org/10.1002/dad2.12148
Staffaroni AM, Weintraub S, Rascovsky K, Rankin KP, Taylor J, Fields JA, Casaletto KB, Hillis AE, Lukic S, Gorno-Tempini ML, Heuer H, Teylan MA, Kukull WA, Miller BL, Boeve BF, Rosen HJ, Boxer AL, Kramer JH. Uniform data set language measures for bvFTD and PPA diagnosis and monitoring. Alzheimers Dement (Amst). 2021 Feb 20;13(1):e12148. doi: 10.1002/dad2.12148. eCollection 2021. PMID: 33665340; PMCID: PMC7896637.
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Enhancing access to innovative cancer drugs: Cross-sector consensus on a way forward to benefit patients.

Drug discovery today

Hoey R, Sharpe E, Kukula A, Workman P.
PMID: 34954130
Drug Discov Today. 2021 Dec 22; doi: 10.1016/j.drudis.2021.12.015. Epub 2021 Dec 22.

New discoveries and technologies are driving major advances in our understanding of cancer and underpinning a new era of precision medicine and immunotherapy. However, advances in treatment have been uneven: whereas survival rates for some common cancers are improving...

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Hoey R, Sharpe E, Kukula A, et al. Enhancing access to innovative cancer drugs: Cross-sector consensus on a way forward to benefit patients. Drug Discov Today. 2021;doi: 10.1016/j.drudis.2021.12.015.
Hoey, R., Sharpe, E., Kukula, A., & Workman, P. (2021). Enhancing access to innovative cancer drugs: Cross-sector consensus on a way forward to benefit patients. Drug discovery today, . https://doi.org/10.1016/j.drudis.2021.12.015
Hoey, Richard, et al. "Enhancing access to innovative cancer drugs: Cross-sector consensus on a way forward to benefit patients." Drug discovery today vol. (2021). doi: https://doi.org/10.1016/j.drudis.2021.12.015
Hoey R, Sharpe E, Kukula A, Workman P. Enhancing access to innovative cancer drugs: Cross-sector consensus on a way forward to benefit patients. Drug Discov Today. 2021 Dec 22; doi: 10.1016/j.drudis.2021.12.015. Epub 2021 Dec 22. PMID: 34954130.
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The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Apostolova LG, Aisen P, Eloyan A, Fagan A, Fargo KN, Foroud T, Gatsonis C, Grinberg LT, Jack CR, Kramer J, Koeppe R, Kukull WA, Murray ME, Nudelman K, Rumbaugh M, Toga A, Vemuri P, Trullinger A, Iaccarino L, Day GS, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Rogalski E, Salloway S, Wolk DA, Wingo TS, Carrillo MC, Dickerson BC, Rabinovici GD.
PMID: 34018654
Alzheimers Dement. 2021 May 21; doi: 10.1002/alz.12350. Epub 2021 May 21.

Patients with early-onset Alzheimer's disease (EOAD) are commonly excluded from large-scale observational and therapeutic studies due to their young age, atypical presentation, or absence of pathogenic mutations. The goals of the Longitudinal EOAD Study (LEADS) are to (1) define...

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Apostolova LG, Aisen P, Eloyan A, et al. The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology. Alzheimers Dement. 2021;doi: 10.1002/alz.12350.
Apostolova, L. G., Aisen, P., Eloyan, A., Fagan, A., Fargo, K. N., Foroud, T., Gatsonis, C., Grinberg, L. T., Jack, C. R., Kramer, J., Koeppe, R., Kukull, W. A., Murray, M. E., Nudelman, K., Rumbaugh, M., Toga, A., Vemuri, P., Trullinger, A., Iaccarino, L., Day, G. S., Graff-Radford, N. R., Honig, L. S., Jones, D. T., Masdeu, J., Mendez, M., Musiek, E., Onyike, C. U., Rogalski, E., Salloway, S., Wolk, D. A., Wingo, T. S., Carrillo, M. C., Dickerson, B. C., Rabinovici, G. D. (2021). The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology. Alzheimer's & dementia : the journal of the Alzheimer's Association, . https://doi.org/10.1002/alz.12350
Apostolova, Liana G, et al. "The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology." Alzheimer's & dementia : the journal of the Alzheimer's Association vol. (2021). doi: https://doi.org/10.1002/alz.12350
Apostolova LG, Aisen P, Eloyan A, Fagan A, Fargo KN, Foroud T, Gatsonis C, Grinberg LT, Jack CR, Kramer J, Koeppe R, Kukull WA, Murray ME, Nudelman K, Rumbaugh M, Toga A, Vemuri P, Trullinger A, Iaccarino L, Day GS, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Rogalski E, Salloway S, Wolk DA, Wingo TS, Carrillo MC, Dickerson BC, Rabinovici GD. The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology. Alzheimers Dement. 2021 May 21; doi: 10.1002/alz.12350. Epub 2021 May 21. PMID: 34018654.
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