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Showing 1 to 6 of 6 entries
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A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells.

Enliven. Challenges in cancer detection and therapy

Xu J, Agyemang S, Qin Y, Aysola K, Giles M, Oprea G, O'Regan RM, Partridge EE, Harris-Hooker S, Rice VM, Reddy ES, Rao VN.
PMID: 25594072
Enliven Chall Cancer Detect Ther. 2014;1(1). doi: 10.18650/2376-046x.11004.

Ovarian cancer is the second most common gynecological cancer and the five-year survival rate is only about 40%. High-grade serous carcinoma is the pre-dominant histotype associated with hereditary ovarian cancer and women with inherited mutations in BRCA1 have a...

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Xu J, Agyemang S, Qin Y, et al. A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells. Enliven Chall Cancer Detect Ther. 2014;1(1)doi: 10.18650/2376-046x.11004.
Xu, J., Agyemang, S., Qin, Y., Aysola, K., Giles, M., Oprea, G., O'Regan, R. M., Partridge, E. E., Harris-Hooker, S., Rice, V. M., Reddy, E. S., & Rao, V. N. (2014). A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells. Enliven. Challenges in cancer detection and therapy, 1(1), . https://doi.org/10.18650/2376-046x.11004
Xu, Jingyao, et al. "A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells." Enliven. Challenges in cancer detection and therapy vol. 1,1 (2014). doi: https://doi.org/10.18650/2376-046x.11004
Xu J, Agyemang S, Qin Y, Aysola K, Giles M, Oprea G, O'Regan RM, Partridge EE, Harris-Hooker S, Rice VM, Reddy ES, Rao VN. A Novel Pathway that Links Caveolin-1 Down-Regulation to BRCA1 Dysfunction in Serous Epithelial Ovarian Cancer Cells. Enliven Chall Cancer Detect Ther. 2014;1(1). doi: 10.18650/2376-046x.11004. PMID: 25594072; PMCID: PMC4292936.
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Epithelial ovarian cancer: An overview.

World journal of translational medicine

Desai A, Xu J, Aysola K, Qin Y, Okoli C, Hariprasad R, Chinemerem U, Gates C, Reddy A, Danner O, Franklin G, Ngozi A, Cantuaria G, Singh K, Grizzle W, Landen C, Partridge EE, Rice VM, Reddy ES, Rao VN.
PMID: 25525571
World J Transl Med. 2014 Apr 12;3(1):1-8. doi: 10.5528/wjtm.v3.i1.1.

Ovarian cancer is the second most common gynecological cancer and the leading cause of death in the United States. In this article we review the diagnosis and current management of epithelial ovarian cancer which accounts for over 95 percent...

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Desai A, Xu J, Aysola K, et al. Epithelial ovarian cancer: An overview. World J Transl Med. 2014;3(1):1-8doi: 10.5528/wjtm.v3.i1.1.
Desai, A., Xu, J., Aysola, K., Qin, Y., Okoli, C., Hariprasad, R., Chinemerem, U., Gates, C., Reddy, A., Danner, O., Franklin, G., Ngozi, A., Cantuaria, G., Singh, K., Grizzle, W., Landen, C., Partridge, E. E., Rice, V. M., Reddy, E. S., & Rao, V. N. (2014). Epithelial ovarian cancer: An overview. World journal of translational medicine, 3(1), 1-8. https://doi.org/10.5528/wjtm.v3.i1.1
Desai, Arpita, et al. "Epithelial ovarian cancer: An overview." World journal of translational medicine vol. 3,1 (2014): 1-8. doi: https://doi.org/10.5528/wjtm.v3.i1.1
Desai A, Xu J, Aysola K, Qin Y, Okoli C, Hariprasad R, Chinemerem U, Gates C, Reddy A, Danner O, Franklin G, Ngozi A, Cantuaria G, Singh K, Grizzle W, Landen C, Partridge EE, Rice VM, Reddy ES, Rao VN. Epithelial ovarian cancer: An overview. World J Transl Med. 2014 Apr 12;3(1):1-8. doi: 10.5528/wjtm.v3.i1.1. PMID: 25525571; PMCID: PMC4267287.
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BRCA1 Mutation Leads to Deregulated Ubc9 Levels which Triggers Proliferation and Migration of Patient-Derived High Grade Serous Ovarian Cancer and Triple Negative Breast Cancer Cells.

International journal of chronic diseases & therapy

Xu J, Footman A, Qin Y, Aysola K, Black S, Reddy V, Singh K, Grizzle W, You S, Moellering D, Reddy ES, Fu Y, Rao VN.
PMID: 28164176
Int J Chronic Dis Ther. 2016;2(3):31-38. Epub 2016 Jun 23.

Women who carry a germline mutation in BRCA1 gene typically develop triple negative breast cancers (TNBC) and high grade serous ovarian cancers (HGSOC). Previously, we reported that wild type BRCA1 proteins, unlike the disease-associated mutant BRCA1 proteins to bind...

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Xu J, Footman A, Qin Y, et al. BRCA1 Mutation Leads to Deregulated Ubc9 Levels which Triggers Proliferation and Migration of Patient-Derived High Grade Serous Ovarian Cancer and Triple Negative Breast Cancer Cells. Int J Chronic Dis Ther. 2016;2(3):31-38
Xu, J., Footman, A., Qin, Y., Aysola, K., Black, S., Reddy, V., Singh, K., Grizzle, W., You, S., Moellering, D., Reddy, E. S., Fu, Y., & Rao, V. N. (2016). BRCA1 Mutation Leads to Deregulated Ubc9 Levels which Triggers Proliferation and Migration of Patient-Derived High Grade Serous Ovarian Cancer and Triple Negative Breast Cancer Cells. International journal of chronic diseases & therapy, 2(3), 31-38.
Xu, J, et al. "BRCA1 Mutation Leads to Deregulated Ubc9 Levels which Triggers Proliferation and Migration of Patient-Derived High Grade Serous Ovarian Cancer and Triple Negative Breast Cancer Cells." International journal of chronic diseases & therapy vol. 2,3 (2016): 31-38.
Xu J, Footman A, Qin Y, Aysola K, Black S, Reddy V, Singh K, Grizzle W, You S, Moellering D, Reddy ES, Fu Y, Rao VN. BRCA1 Mutation Leads to Deregulated Ubc9 Levels which Triggers Proliferation and Migration of Patient-Derived High Grade Serous Ovarian Cancer and Triple Negative Breast Cancer Cells. Int J Chronic Dis Ther. 2016;2(3):31-38. Epub 2016 Jun 23. PMID: 28164176; PMCID: PMC5287352.
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BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9.

American journal of cancer research

Qin Y, Xu J, Aysola K, Oprea G, Reddy A, Matthews R, Okoli J, Cantor A, Grizzle WE, Partridge EE, Reddy ES, Landen C, Rao VN.
PMID: 22957306
Am J Cancer Res. 2012;2(5):540-8. Epub 2012 Aug 20.

Mutation in the BRCA1 gene is associated with increased risk for hereditary breast and ovarian cancers. In sporadic ovarian tumors, BRCA1 dysfunction is thought to be common. BRCA1 is a nuclear-cytoplasm shuttling protein. Our group has previously reported that...

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Qin Y, Xu J, Aysola K, et al. BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9. Am J Cancer Res. 2012;2(5):540-8
Qin, Y., Xu, J., Aysola, K., Oprea, G., Reddy, A., Matthews, R., Okoli, J., Cantor, A., Grizzle, W. E., Partridge, E. E., Reddy, E. S., Landen, C., & Rao, V. N. (2012). BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9. American journal of cancer research, 2(5), 540-8.
Qin, Yunlong, et al. "BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9." American journal of cancer research vol. 2,5 (2012): 540-8.
Qin Y, Xu J, Aysola K, Oprea G, Reddy A, Matthews R, Okoli J, Cantor A, Grizzle WE, Partridge EE, Reddy ES, Landen C, Rao VN. BRCA1 proteins regulate growth of ovarian cancer cells by tethering Ubc9. Am J Cancer Res. 2012;2(5):540-8. Epub 2012 Aug 20. PMID: 22957306; PMCID: PMC3433105.
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Triple Negative Breast Cancer - An Overview.

Hereditary genetics : current research

Aysola K, Desai A, Welch C, Xu J, Qin Y, Reddy V, Matthews R, Owens C, Okoli J, Beech DJ, Piyathilake CJ, Reddy SP, Rao VN.
PMID: 25285241
Hereditary Genet. 2013;2013. doi: 10.4172/2161-1041.S2-001.

Triple Negative Breast Cancer (TNBC) is a heterogeneous disease that based on immunohistochemistry (IHC) is estrogen receptor (ER) negative, progesterone receptor (PR) negative and human epidermal growth factor receptor 2 (HER2) negative. TNBC is typically observed in young AA...

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Aysola K, Desai A, Welch C, et al. Triple Negative Breast Cancer - An Overview. Hereditary Genet. 2013;2013doi: 10.4172/2161-1041.S2-001.
Aysola, K., Desai, A., Welch, C., Xu, J., Qin, Y., Reddy, V., Matthews, R., Owens, C., Okoli, J., Beech, D. J., Piyathilake, C. J., Reddy, S. P., & Rao, V. N. (2013). Triple Negative Breast Cancer - An Overview. Hereditary genetics : current research, 2013. https://doi.org/10.4172/2161-1041.S2-001
Aysola, Kartik, et al. "Triple Negative Breast Cancer - An Overview." Hereditary genetics : current research vol. 2013 (2013). doi: https://doi.org/10.4172/2161-1041.S2-001
Aysola K, Desai A, Welch C, Xu J, Qin Y, Reddy V, Matthews R, Owens C, Okoli J, Beech DJ, Piyathilake CJ, Reddy SP, Rao VN. Triple Negative Breast Cancer - An Overview. Hereditary Genet. 2013;2013. doi: 10.4172/2161-1041.S2-001. PMID: 25285241; PMCID: PMC4181680.
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Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites.

Journal of gynecology research

Desai A, Xu J, Aysola K, Akinbobuyi O, White M, Reddy VE, Okoli J, Clark C, Partridge EE, Childs E, Beech DJ, Rice MV, Reddy E, Rao VN.
PMID: 26665166
J Gynecol Res. 2015;1(1). doi: 10.15744/2454-3284.1.103. Epub 2015 Apr 24.

Ovarian cancer constitutes the second most common gynecological cancer with a five-year survival rate of 40%. Among the various histotypes associated with hereditary ovarian cancer, high-grade serous epithelial ovarian carcinoma (HGSEOC) is the most predominant and women with inherited...

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Desai A, Xu J, Aysola K, et al. Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites. J Gynecol Res. 2015;1(1)doi: 10.15744/2454-3284.1.103.
Desai, A., Xu, J., Aysola, K., Akinbobuyi, O., White, M., Reddy, V. E., Okoli, J., Clark, C., Partridge, E. E., Childs, E., Beech, D. J., Rice, M. V., Reddy, E., & Rao, V. N. (2015). Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites. Journal of gynecology research, 1(1), . https://doi.org/10.15744/2454-3284.1.103
Desai, A, et al. "Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites." Journal of gynecology research vol. 1,1 (2015). doi: https://doi.org/10.15744/2454-3284.1.103
Desai A, Xu J, Aysola K, Akinbobuyi O, White M, Reddy VE, Okoli J, Clark C, Partridge EE, Childs E, Beech DJ, Rice MV, Reddy E, Rao VN. Molecular Mechanism Linking BRCA1 Dysfunction to High Grade Serous Epithelial Ovarian Cancers with Peritoneal Permeability and Ascites. J Gynecol Res. 2015;1(1). doi: 10.15744/2454-3284.1.103. Epub 2015 Apr 24. PMID: 26665166; PMCID: PMC4671517.
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Showing 1 to 6 of 6 entries