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Substance Abuse and Excessive Mortality Among Forensic Psychiatric Patients: A Finnish Nationwide Cohort Study.

Frontiers in psychiatry

Ojansuu I, Putkonen H, Lähteenvuo M, Tiihonen J.
PMID: 31572247
Front Psychiatry. 2019 Sep 13;10:678. doi: 10.3389/fpsyt.2019.00678. eCollection 2019.

No abstract available.

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Ojansuu I, Putkonen H, Lähteenvuo M, et al. Substance Abuse and Excessive Mortality Among Forensic Psychiatric Patients: A Finnish Nationwide Cohort Study. Front Psychiatry. 2019;10:678doi: 10.3389/fpsyt.2019.00678.
Ojansuu, I., Putkonen, H., Lähteenvuo, M., & Tiihonen, J. (2019). Substance Abuse and Excessive Mortality Among Forensic Psychiatric Patients: A Finnish Nationwide Cohort Study. Frontiers in psychiatry, 10678. https://doi.org/10.3389/fpsyt.2019.00678
Ojansuu, Ilkka, et al. "Substance Abuse and Excessive Mortality Among Forensic Psychiatric Patients: A Finnish Nationwide Cohort Study." Frontiers in psychiatry vol. 10 (2019): 678. doi: https://doi.org/10.3389/fpsyt.2019.00678
Ojansuu I, Putkonen H, Lähteenvuo M, Tiihonen J. Substance Abuse and Excessive Mortality Among Forensic Psychiatric Patients: A Finnish Nationwide Cohort Study. Front Psychiatry. 2019 Sep 13;10:678. doi: 10.3389/fpsyt.2019.00678. eCollection 2019. PMID: 31572247; PMCID: PMC6754090.
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Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder.

Schizophrenia bulletin

Lintunen J, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J, Lähteenvuo M, Story M.
PMID: 33533399
Schizophr Bull. 2021 Jul 08;47(4):1099-1107. doi: 10.1093/schbul/sbab004.

OBJECTIVE: To investigate the long-term real-world effectiveness of antipsychotics and other psychopharmacotherapies in the treatment of schizoaffective disorder (SCHAFF).METHOD: Two nationwide cohorts of SCHAFF patients were identified from Finnish and Swedish registers. Within-individual design was used with stratified Cox...

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Lintunen J, Taipale H, Tanskanen A, et al. Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder. Schizophr Bull. 2021;47(4):1099-1107doi: 10.1093/schbul/sbab004.
Lintunen, J., Taipale, H., Tanskanen, A., Mittendorfer-Rutz, E., Tiihonen, J., Lähteenvuo, M., & Story, M. (2021). Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder. Schizophrenia bulletin, 47(4), 1099-1107. https://doi.org/10.1093/schbul/sbab004
Lintunen, Jonne, et al. "Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder." Schizophrenia bulletin vol. 47,4 (2021): 1099-1107. doi: https://doi.org/10.1093/schbul/sbab004
Lintunen J, Taipale H, Tanskanen A, Mittendorfer-Rutz E, Tiihonen J, Lähteenvuo M, Story M. Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder. Schizophr Bull. 2021 Jul 08;47(4):1099-1107. doi: 10.1093/schbul/sbab004. PMID: 33533399; PMCID: PMC8266596.
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Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder.

Brain sciences

Mazumder AH, Barnett J, Isometsä ET, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Ahola-Olli A, Hietala J, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, Wegelius A, Männynsalo T, Niemi-Pynttäri J, Suokas K, Lönnqvist J, Tiihonen J, Paunio T, Vainio SJ, Palotie A, Niemelä S, Suvisaari J, Veijola J.
PMID: 34827421
Brain Sci. 2021 Oct 27;11(11). doi: 10.3390/brainsci11111422.

The purpose of this study was to explore the association of cognition with hazardous drinking Polygenic Scores (PGS) in 2649 schizophrenia, 558 schizoaffective disorder, and 1125 bipolar disorder patients in Finland. Hazardous drinking PGS was computed using the LDPred...

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Mazumder AH, Barnett J, Isometsä ET, et al. Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder. Brain Sci. 2021;11(11)doi: 10.3390/brainsci11111422.
Mazumder, A. H., Barnett, J., Isometsä, E. T., Lindberg, N., Torniainen-Holm, M., Lähteenvuo, M., Lahdensuo, K., Kerkelä, M., Ahola-Olli, A., Hietala, J., Kampman, O., Kieseppä, T., Jukuri, T., Häkkinen, K., Cederlöf, E., Haaki, W., Kajanne, R., Wegelius, A., Männynsalo, T., Niemi-Pynttäri, J., Suokas, K., Lönnqvist, J., Tiihonen, J., Paunio, T., Vainio, S. J., Palotie, A., Niemelä, S., Suvisaari, J., & Veijola, J. (2021). Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder. Brain sciences, 11(11), . https://doi.org/10.3390/brainsci11111422
Mazumder, Atiqul Haq, et al. "Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder." Brain sciences vol. 11,11 (2021). doi: https://doi.org/10.3390/brainsci11111422
Mazumder AH, Barnett J, Isometsä ET, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Ahola-Olli A, Hietala J, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, Wegelius A, Männynsalo T, Niemi-Pynttäri J, Suokas K, Lönnqvist J, Tiihonen J, Paunio T, Vainio SJ, Palotie A, Niemelä S, Suvisaari J, Veijola J. Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder. Brain Sci. 2021 Oct 27;11(11). doi: 10.3390/brainsci11111422. PMID: 34827421; PMCID: PMC8615595.
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Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia.

NPJ schizophrenia

Lintunen J, Lähteenvuo M, Tiihonen J, Tanskanen A, Taipale H.
PMID: 33479257
NPJ Schizophr. 2021 Jan 21;7(1):1. doi: 10.1038/s41537-020-00135-y.

Relapses remain common among individuals with schizophrenia indicating a need for improved treatments. Creating a completely new drug molecule is expensive and time consuming, and therefore drug repurposing should be considered. Aim of this study was to investigate the...

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Lintunen J, Lähteenvuo M, Tiihonen J, et al. Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia. NPJ Schizophr. 2021;7(1):1doi: 10.1038/s41537-020-00135-y.
Lintunen, J., Lähteenvuo, M., Tiihonen, J., Tanskanen, A., & Taipale, H. (2021). Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia. NPJ schizophrenia, 7(1), 1. https://doi.org/10.1038/s41537-020-00135-y
Lintunen, Jonne, et al. "Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia." NPJ schizophrenia vol. 7,1 (2021): 1. doi: https://doi.org/10.1038/s41537-020-00135-y
Lintunen J, Lähteenvuo M, Tiihonen J, Tanskanen A, Taipale H. Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia. NPJ Schizophr. 2021 Jan 21;7(1):1. doi: 10.1038/s41537-020-00135-y. PMID: 33479257; PMCID: PMC7820462.
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A Systematic Literature Review of Neuroimaging of Psychopathic Traits.

Frontiers in psychiatry

Johanson M, Vaurio O, Tiihonen J, Lähteenvuo M.
PMID: 32116828
Front Psychiatry. 2020 Feb 06;10:1027. doi: 10.3389/fpsyt.2019.01027. eCollection 2019.

INTRODUCTION: Core psychopathy is characterized by grandiosity, callousness, manipulativeness, and lack of remorse, empathy, and guilt. It is often comorbid with conduct disorder and antisocial personality disorder (ASPD). Psychopathy is present in forensic as well as prison and general...

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Johanson M, Vaurio O, Tiihonen J, et al. A Systematic Literature Review of Neuroimaging of Psychopathic Traits. Front Psychiatry. 2020;10:1027doi: 10.3389/fpsyt.2019.01027.
Johanson, M., Vaurio, O., Tiihonen, J., & Lähteenvuo, M. (2019). A Systematic Literature Review of Neuroimaging of Psychopathic Traits. Frontiers in psychiatry, 101027. https://doi.org/10.3389/fpsyt.2019.01027
Johanson, Mika, et al. "A Systematic Literature Review of Neuroimaging of Psychopathic Traits." Frontiers in psychiatry vol. 10 (2019): 1027. doi: https://doi.org/10.3389/fpsyt.2019.01027
Johanson M, Vaurio O, Tiihonen J, Lähteenvuo M. A Systematic Literature Review of Neuroimaging of Psychopathic Traits. Front Psychiatry. 2020 Feb 06;10:1027. doi: 10.3389/fpsyt.2019.01027. eCollection 2019. PMID: 32116828; PMCID: PMC7016047.
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Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia.

Glia

Koskuvi M, Lehtonen Š, Trontti K, Keuters M, Wu YC, Koivisto H, Ludwig A, Plotnikova L, Virtanen PLJ, Räsänen N, Kaipainen S, Hyötyläinen I, Dhungana H, Giniatullina R, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Lähteenvuo M, Tohka J, Giniatullin R, Rivera C, Hovatta I, Tanila H, Tiihonen J, Koistinaho J.
PMID: 34936134
Glia. 2021 Dec 22; doi: 10.1002/glia.24131. Epub 2021 Dec 22.

Previous studies have implicated several brain cell types in schizophrenia (SCZ), but the genetic impact of astrocytes is unknown. Considering their high complexity in humans, astrocytes are likely key determinants of neurodevelopmental diseases, such as SCZ. Human induced pluripotent...

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Koskuvi M, Lehtonen Š, Trontti K, et al. Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia. Glia. 2021;doi: 10.1002/glia.24131.
Koskuvi, M., Lehtonen, �. �., Trontti, K., Keuters, M., Wu, Y. C., Koivisto, H., Ludwig, A., Plotnikova, L., Virtanen, P. L. J., Räsänen, N., Kaipainen, S., Hyötyläinen, I., Dhungana, H., Giniatullina, R., Ojansuu, I., Vaurio, O., Cannon, T. D., Lönnqvist, J., Therman, S., Suvisaari, J., Kaprio, J., Lähteenvuo, M., Tohka, J., Giniatullin, R., Rivera, C., Hovatta, I., Tanila, H., Tiihonen, J., & Koistinaho, J. (2021). Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia. Glia, . https://doi.org/10.1002/glia.24131
Koskuvi, Marja, et al. "Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia." Glia vol. (2021). doi: https://doi.org/10.1002/glia.24131
Koskuvi M, Lehtonen Š, Trontti K, Keuters M, Wu YC, Koivisto H, Ludwig A, Plotnikova L, Virtanen PLJ, Räsänen N, Kaipainen S, Hyötyläinen I, Dhungana H, Giniatullina R, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Lähteenvuo M, Tohka J, Giniatullin R, Rivera C, Hovatta I, Tanila H, Tiihonen J, Koistinaho J. Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia. Glia. 2021 Dec 22; doi: 10.1002/glia.24131. Epub 2021 Dec 22. PMID: 34936134.
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Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder.

Brain sciences

Mazumder AH, Barnett J, Isometsä ET, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Ahola-Olli A, Hietala J, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, Wegelius A, Männynsalo T, Niemi-Pynttäri J, Suokas K, Lönnqvist J, Tiihonen J, Paunio T, Vainio SJ, Palotie A, Niemelä S, Suvisaari J, Veijola J.
PMID: 34573174
Brain Sci. 2021 Aug 30;11(9). doi: 10.3390/brainsci11091154.

The purpose of this study was to explore the association of cognition with hazardous drinking and alcohol-related disorder in persons with bipolar disorder (BD). The study population included 1268 persons from Finland with bipolar disorder. Alcohol use was assessed...

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Mazumder AH, Barnett J, Isometsä ET, et al. Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder. Brain Sci. 2021;11(9)doi: 10.3390/brainsci11091154.
Mazumder, A. H., Barnett, J., Isometsä, E. T., Lindberg, N., Torniainen-Holm, M., Lähteenvuo, M., Lahdensuo, K., Kerkelä, M., Ahola-Olli, A., Hietala, J., Kampman, O., Kieseppä, T., Jukuri, T., Häkkinen, K., Cederlöf, E., Haaki, W., Kajanne, R., Wegelius, A., Männynsalo, T., Niemi-Pynttäri, J., Suokas, K., Lönnqvist, J., Tiihonen, J., Paunio, T., Vainio, S. J., Palotie, A., Niemelä, S., Suvisaari, J., & Veijola, J. (2021). Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder. Brain sciences, 11(9), . https://doi.org/10.3390/brainsci11091154
Mazumder, Atiqul Haq, et al. "Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder." Brain sciences vol. 11,9 (2021). doi: https://doi.org/10.3390/brainsci11091154
Mazumder AH, Barnett J, Isometsä ET, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Ahola-Olli A, Hietala J, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, Wegelius A, Männynsalo T, Niemi-Pynttäri J, Suokas K, Lönnqvist J, Tiihonen J, Paunio T, Vainio SJ, Palotie A, Niemelä S, Suvisaari J, Veijola J. Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder. Brain Sci. 2021 Aug 30;11(9). doi: 10.3390/brainsci11091154. PMID: 34573174; PMCID: PMC8467646.
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Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study.

Schizophrenia bulletin

Solmi M, Tiihonen J, Lähteenvuo M, Tanskanen A, Correll CU, Taipale H.
PMID: 34286338
Schizophr Bull. 2021 Jul 21; doi: 10.1093/schbul/sbab087. Epub 2021 Jul 21.

BACKGROUND: People with schizophrenia/schizoaffective disorder (schizophrenia) die early, largely due to cardiovascular-related mortality. Antipsychotics are associated with lower mortality. We aimed to explore whether antipsychotic use can reduce discontinuation of medications for cardiovascular risk factors and diseases ("cardiometacolic drugs"),...

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Solmi M, Tiihonen J, Lähteenvuo M, et al. Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study. Schizophr Bull. 2021;doi: 10.1093/schbul/sbab087.
Solmi, M., Tiihonen, J., Lähteenvuo, M., Tanskanen, A., Correll, C. U., & Taipale, H. (2021). Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study. Schizophrenia bulletin, . https://doi.org/10.1093/schbul/sbab087
Solmi, Marco, et al. "Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study." Schizophrenia bulletin vol. (2021). doi: https://doi.org/10.1093/schbul/sbab087
Solmi M, Tiihonen J, Lähteenvuo M, Tanskanen A, Correll CU, Taipale H. Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study. Schizophr Bull. 2021 Jul 21; doi: 10.1093/schbul/sbab087. Epub 2021 Jul 21. PMID: 34286338.
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Correction: Neurobiological roots of psychopathy.

Molecular psychiatry

Tiihonen J, Koskuvi M, Lähteenvuo M, Virtanen PLJ, Ojansuu I, Vaurio O, Gao Y, Hyötyläinen I, Puttonen KA, Repo-Tiihonen E, Paunio T, Rautiainen MR, Tyni S, Koistinaho J, Lehtonen Š.
PMID: 31570776
Mol Psychiatry. 2020 Dec;25(12):3455-3456. doi: 10.1038/s41380-019-0528-8.

A correction to this paper has been published and can be accessed via a link at the top of the paper.

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Tiihonen J, Koskuvi M, Lähteenvuo M, et al. Correction: Neurobiological roots of psychopathy. Mol Psychiatry. 2020;25(12):3455-3456doi: 10.1038/s41380-019-0528-8.
Tiihonen, J., Koskuvi, M., Lähteenvuo, M., Virtanen, P. L. J., Ojansuu, I., Vaurio, O., Gao, Y., Hyötyläinen, I., Puttonen, K. A., Repo-Tiihonen, E., Paunio, T., Rautiainen, M. R., Tyni, S., Koistinaho, J., & Lehtonen, �. �. (2020). Correction: Neurobiological roots of psychopathy. Molecular psychiatry, 25(12), 3455-3456. https://doi.org/10.1038/s41380-019-0528-8
Tiihonen, Jari, et al. "Correction: Neurobiological roots of psychopathy." Molecular psychiatry vol. 25,12 (2020): 3455-3456. doi: https://doi.org/10.1038/s41380-019-0528-8
Tiihonen J, Koskuvi M, Lähteenvuo M, Virtanen PLJ, Ojansuu I, Vaurio O, Gao Y, Hyötyläinen I, Puttonen KA, Repo-Tiihonen E, Paunio T, Rautiainen MR, Tyni S, Koistinaho J, Lehtonen Š. Correction: Neurobiological roots of psychopathy. Mol Psychiatry. 2020 Dec;25(12):3455-3456. doi: 10.1038/s41380-019-0528-8. PMID: 31570776; PMCID: PMC7714682.
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Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations.

Drugs

Lähteenvuo M, Tiihonen J.
PMID: 34196945
Drugs. 2021 Jul;81(11):1273-1284. doi: 10.1007/s40265-021-01556-4. Epub 2021 Jul 01.

Schizophrenia is a debilitating illness with a lifetime prevalence estimate of 0.6% and consists of symptoms from the positive, negative, and cognitive domains. Social support, therapy, psychoeducation, and overall case management are very important aspects of the treatment of...

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Lähteenvuo M, Tiihonen J. Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations. Drugs. 2021;81(11):1273-1284doi: 10.1007/s40265-021-01556-4.
Lähteenvuo, M., & Tiihonen, J. (2021). Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations. Drugs, 81(11), 1273-1284. https://doi.org/10.1007/s40265-021-01556-4
Lähteenvuo, Markku, and Tiihonen, Jari. "Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations." Drugs vol. 81,11 (2021): 1273-1284. doi: https://doi.org/10.1007/s40265-021-01556-4
Lähteenvuo M, Tiihonen J. Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations. Drugs. 2021 Jul;81(11):1273-1284. doi: 10.1007/s40265-021-01556-4. Epub 2021 Jul 01. PMID: 34196945; PMCID: PMC8318953.
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Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder.

Brain sciences

Mazumder AH, Barnett J, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Hietala J, Isometsä ET, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, Wegelius A, Männynsalo T, Niemi-Pynttäri J, Suokas K, Lönnqvist J, Niemelä S, Tiihonen J, Paunio T, Palotie A, Suvisaari J, Veijola J.
PMID: 34071123
Brain Sci. 2021 May 23;11(6). doi: 10.3390/brainsci11060688.

The purpose of this study was to explore the association between cognition and hazardous drinking and alcohol use disorder in schizophrenia and schizoaffective disorder. Cognition is more or less compromised in schizophrenia, and schizoaffective disorder and alcohol use might...

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Mazumder AH, Barnett J, Lindberg N, et al. Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder. Brain Sci. 2021;11(6)doi: 10.3390/brainsci11060688.
Mazumder, A. H., Barnett, J., Lindberg, N., Torniainen-Holm, M., Lähteenvuo, M., Lahdensuo, K., Kerkelä, M., Hietala, J., Isometsä, E. T., Kampman, O., Kieseppä, T., Jukuri, T., Häkkinen, K., Cederlöf, E., Haaki, W., Kajanne, R., Wegelius, A., Männynsalo, T., Niemi-Pynttäri, J., Suokas, K., Lönnqvist, J., Niemelä, S., Tiihonen, J., Paunio, T., Palotie, A., Suvisaari, J., & Veijola, J. (2021). Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder. Brain sciences, 11(6), . https://doi.org/10.3390/brainsci11060688
Mazumder, Atiqul Haq, et al. "Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder." Brain sciences vol. 11,6 (2021). doi: https://doi.org/10.3390/brainsci11060688
Mazumder AH, Barnett J, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Hietala J, Isometsä ET, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, Wegelius A, Männynsalo T, Niemi-Pynttäri J, Suokas K, Lönnqvist J, Niemelä S, Tiihonen J, Paunio T, Palotie A, Suvisaari J, Veijola J. Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder. Brain Sci. 2021 May 23;11(6). doi: 10.3390/brainsci11060688. PMID: 34071123; PMCID: PMC8224767.
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The European Medicines Agency Review of Crizanlizumab for the Prevention of Recurrent Vaso-Occlusive Crises in Patients With Sickle Cell Disease.

HemaSphere

Delgado J, Voltz C, Stain M, Lapveteläinen T, Urach S, Lähteenvuo J, Penttilä K, Gisselbrecht C, Enzmann H, Pignatti F.
PMID: 34235401
Hemasphere. 2021 Jun 28;5(7):e604. doi: 10.1097/HS9.0000000000000604. eCollection 2021 Jul.

Crizanlizumab is a monoclonal antibody that binds to P-selectin. On October 28, 2020, a conditional marketing authorization valid through the European Union (EU) was issued for crizanlizumab for the prevention of recurrent vaso-occlusive crises (VOCs) in patients with sickle...

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Delgado J, Voltz C, Stain M, et al. The European Medicines Agency Review of Crizanlizumab for the Prevention of Recurrent Vaso-Occlusive Crises in Patients With Sickle Cell Disease. Hemasphere. 2021;5(7):e604doi: 10.1097/HS9.0000000000000604.
Delgado, J., Voltz, C., Stain, M., Lapveteläinen, T., Urach, S., Lähteenvuo, J., Penttilä, K., Gisselbrecht, C., Enzmann, H., & Pignatti, F. (2021). The European Medicines Agency Review of Crizanlizumab for the Prevention of Recurrent Vaso-Occlusive Crises in Patients With Sickle Cell Disease. HemaSphere, 5(7), e604. https://doi.org/10.1097/HS9.0000000000000604
Delgado, Julio, et al. "The European Medicines Agency Review of Crizanlizumab for the Prevention of Recurrent Vaso-Occlusive Crises in Patients With Sickle Cell Disease." HemaSphere vol. 5,7 (2021): e604. doi: https://doi.org/10.1097/HS9.0000000000000604
Delgado J, Voltz C, Stain M, Lapveteläinen T, Urach S, Lähteenvuo J, Penttilä K, Gisselbrecht C, Enzmann H, Pignatti F. The European Medicines Agency Review of Crizanlizumab for the Prevention of Recurrent Vaso-Occlusive Crises in Patients With Sickle Cell Disease. Hemasphere. 2021 Jun 28;5(7):e604. doi: 10.1097/HS9.0000000000000604. eCollection 2021 Jul. PMID: 34235401; PMCID: PMC8240778.
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