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New insights into the role of macrophages in adipose tissue inflammation and Fatty liver disease: modulation by endogenous omega-3 Fatty Acid-derived lipid mediators.

Frontiers in immunology

Clària J, González-Périz A, López-Vicario C, Rius B, Titos E.
PMID: 22566839
Front Immunol. 2011 Oct 05;2:49. doi: 10.3389/fimmu.2011.00049. eCollection 2011.

Obesity is causally linked to a chronic state of "low-grade" inflammation in adipose tissue. Prolonged, unremitting inflammation in this tissue has a direct impact on insulin-sensitive tissues (i.e., liver) and its timely resolution is a critical step toward reducing...

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Clària J, González-Périz A, López-Vicario C, et al. New insights into the role of macrophages in adipose tissue inflammation and Fatty liver disease: modulation by endogenous omega-3 Fatty Acid-derived lipid mediators. Front Immunol. 2011;2:49doi: 10.3389/fimmu.2011.00049.
Clària, J., González-Périz, A., López-Vicario, C., Rius, B., & Titos, E. (2011). New insights into the role of macrophages in adipose tissue inflammation and Fatty liver disease: modulation by endogenous omega-3 Fatty Acid-derived lipid mediators. Frontiers in immunology, 249. https://doi.org/10.3389/fimmu.2011.00049
Clària, Joan, et al. "New insights into the role of macrophages in adipose tissue inflammation and Fatty liver disease: modulation by endogenous omega-3 Fatty Acid-derived lipid mediators." Frontiers in immunology vol. 2 (2011): 49. doi: https://doi.org/10.3389/fimmu.2011.00049
Clària J, González-Périz A, López-Vicario C, Rius B, Titos E. New insights into the role of macrophages in adipose tissue inflammation and Fatty liver disease: modulation by endogenous omega-3 Fatty Acid-derived lipid mediators. Front Immunol. 2011 Oct 05;2:49. doi: 10.3389/fimmu.2011.00049. eCollection 2011. PMID: 22566839; PMCID: PMC3342277.
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Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure.

Journal of hepatology

Zhang IW, Curto A, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Colsch B, Aguilar F, Aransay AM, Lozano JJ, Hernández-Tejero M, Toapanta D, Fernández J, Arroyo V, Clària J.
PMID: 34450236
J Hepatol. 2021 Aug 25; doi: 10.1016/j.jhep.2021.08.009. Epub 2021 Aug 25.

BACKGROUND & AIMS: Patients with acute-on-chronic liver failure (ACLF) present a systemic hyperinflammatory response associated with increased circulating levels of small-molecule metabolites. To investigate whether these alterations reflect inadequate cell energy output, we assessed mitochondrial morphology and central metabolic...

Cite
Zhang IW, Curto A, López-Vicario C, et al. Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure. J Hepatol. 2021;doi: 10.1016/j.jhep.2021.08.009.
Zhang, I. W., Curto, A., López-Vicario, C., Casulleras, M., Duran-Güell, M., Flores-Costa, R., Colsch, B., Aguilar, F., Aransay, A. M., Lozano, J. J., Hernández-Tejero, M., Toapanta, D., Fernández, J., Arroyo, V., & Clària, J. (2021). Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure. Journal of hepatology, . https://doi.org/10.1016/j.jhep.2021.08.009
Zhang, Ingrid W, et al. "Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure." Journal of hepatology vol. (2021). doi: https://doi.org/10.1016/j.jhep.2021.08.009
Zhang IW, Curto A, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Colsch B, Aguilar F, Aransay AM, Lozano JJ, Hernández-Tejero M, Toapanta D, Fernández J, Arroyo V, Clària J. Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure. J Hepatol. 2021 Aug 25; doi: 10.1016/j.jhep.2021.08.009. Epub 2021 Aug 25. PMID: 34450236.
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Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis.

Journal of hepatology

Clària J, Curto A, Moreau R, Colsch B, López-Vicario C, Lozano JJ, Aguilar F, Castelli FA, Fenaille F, Junot C, Zhang I, Vinaixa M, Yanes O, Caraceni P, Trebicka J, Fernández J, Angeli P, Jalan R, Arroyo V.
PMID: 34245803
J Hepatol. 2021 Nov;75(5):1116-1127. doi: 10.1016/j.jhep.2021.06.043. Epub 2021 Jul 07.

BACKGROUND & AIMS: Acute decompensation (AD) of cirrhosis is a heterogeneous clinical entity associated with moderate mortality. In some patients, this condition develops quickly into the more deadly acute-on-chronic liver failure (ACLF), in which other organs such as the...

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Clària J, Curto A, Moreau R, et al. Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis. J Hepatol. 2021;75(5):1116-1127doi: 10.1016/j.jhep.2021.06.043.
Clària, J., Curto, A., Moreau, R., Colsch, B., López-Vicario, C., Lozano, J. J., Aguilar, F., Castelli, F. A., Fenaille, F., Junot, C., Zhang, I., Vinaixa, M., Yanes, O., Caraceni, P., Trebicka, J., Fernández, J., Angeli, P., Jalan, R., & Arroyo, V. (2021). Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis. Journal of hepatology, 75(5), 1116-1127. https://doi.org/10.1016/j.jhep.2021.06.043
Clària, Joan, et al. "Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis." Journal of hepatology vol. 75,5 (2021): 1116-1127. doi: https://doi.org/10.1016/j.jhep.2021.06.043
Clària J, Curto A, Moreau R, Colsch B, López-Vicario C, Lozano JJ, Aguilar F, Castelli FA, Fenaille F, Junot C, Zhang I, Vinaixa M, Yanes O, Caraceni P, Trebicka J, Fernández J, Angeli P, Jalan R, Arroyo V. Untargeted lipidomics uncovers lipid signatures that distinguish severe from moderate forms of acutely decompensated cirrhosis. J Hepatol. 2021 Nov;75(5):1116-1127. doi: 10.1016/j.jhep.2021.06.043. Epub 2021 Jul 07. PMID: 34245803.
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Resolution of inflammation in obesity-induced liver disease.

Frontiers in immunology

Rius B, López-Vicario C, González-Périz A, Morán-Salvador E, García-Alonso V, Clária J, Titos E.
PMID: 22934096
Front Immunol. 2012 Aug 20;3:257. doi: 10.3389/fimmu.2012.00257. eCollection 2012.

Low-grade inflammation in adipose tissue is recognized as a critical event in the development of obesity-related co-morbidities. This chronic inflammation is powerfully augmented through the infiltration of macrophages, which together with adipocytes, perpetuate a vicious cycle of inflammatory cell...

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Rius B, López-Vicario C, González-Périz A, et al. Resolution of inflammation in obesity-induced liver disease. Front Immunol. 2012;3:257doi: 10.3389/fimmu.2012.00257.
Rius, B., López-Vicario, C., González-Périz, A., Morán-Salvador, E., García-Alonso, V., Clária, J., & Titos, E. (2012). Resolution of inflammation in obesity-induced liver disease. Frontiers in immunology, 3257. https://doi.org/10.3389/fimmu.2012.00257
Rius, Bibiana, et al. "Resolution of inflammation in obesity-induced liver disease." Frontiers in immunology vol. 3 (2012): 257. doi: https://doi.org/10.3389/fimmu.2012.00257
Rius B, López-Vicario C, González-Périz A, Morán-Salvador E, García-Alonso V, Clária J, Titos E. Resolution of inflammation in obesity-induced liver disease. Front Immunol. 2012 Aug 20;3:257. doi: 10.3389/fimmu.2012.00257. eCollection 2012. PMID: 22934096; PMCID: PMC3422856.
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Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts.

Frontiers in molecular biosciences

Zhang IW, López-Vicario C, Duran-Güell M, Clària J.
PMID: 34888354
Front Mol Biosci. 2021 Nov 23;8:772174. doi: 10.3389/fmolb.2021.772174. eCollection 2021.

Mitochondria are entrusted with the challenging task of providing energy through the generation of ATP, the universal cellular currency, thereby being highly flexible to different acute and chronic nutrient demands of the cell. The fact that mitochondrial diseases (genetic...

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Zhang IW, López-Vicario C, Duran-Güell M, et al. Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts. Front Mol Biosci. 2021;8:772174doi: 10.3389/fmolb.2021.772174.
Zhang, I. W., López-Vicario, C., Duran-Güell, M., & Clària, J. (2021). Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts. Frontiers in molecular biosciences, 8772174. https://doi.org/10.3389/fmolb.2021.772174
Zhang, Ingrid W, et al. "Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts." Frontiers in molecular biosciences vol. 8 (2021): 772174. doi: https://doi.org/10.3389/fmolb.2021.772174
Zhang IW, López-Vicario C, Duran-Güell M, Clària J. Mitochondrial Dysfunction in Advanced Liver Disease: Emerging Concepts. Front Mol Biosci. 2021 Nov 23;8:772174. doi: 10.3389/fmolb.2021.772174. eCollection 2021. PMID: 34888354; PMCID: PMC8650317.
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Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure.

Journal of hepatology

Zhang IW, Curto A, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Colsch B, Aguilar F, Aransay AM, Lozano JJ, Hernández-Tejero M, Toapanta D, Fernández J, Arroyo V, Clària J.
PMID: 34450236
J Hepatol. 2022 Jan;76(1):93-106. doi: 10.1016/j.jhep.2021.08.009. Epub 2021 Aug 25.

BACKGROUND & AIMS: Patients with acute-on-chronic liver failure (ACLF) present a systemic hyperinflammatory response associated with increased circulating levels of small-molecule metabolites. To investigate whether these alterations reflect inadequate cell energy output, we assessed mitochondrial morphology and central metabolic...

Cite
Zhang IW, Curto A, López-Vicario C, et al. Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure. J Hepatol. 2021;76(1):93-106doi: 10.1016/j.jhep.2021.08.009.
Zhang, I. W., Curto, A., López-Vicario, C., Casulleras, M., Duran-Güell, M., Flores-Costa, R., Colsch, B., Aguilar, F., Aransay, A. M., Lozano, J. J., Hernández-Tejero, M., Toapanta, D., Fernández, J., Arroyo, V., & Clària, J. (2022). Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure. Journal of hepatology, 76(1), 93-106. https://doi.org/10.1016/j.jhep.2021.08.009
Zhang, Ingrid W, et al. "Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure." Journal of hepatology vol. 76,1 (2022): 93-106. doi: https://doi.org/10.1016/j.jhep.2021.08.009
Zhang IW, Curto A, López-Vicario C, Casulleras M, Duran-Güell M, Flores-Costa R, Colsch B, Aguilar F, Aransay AM, Lozano JJ, Hernández-Tejero M, Toapanta D, Fernández J, Arroyo V, Clària J. Mitochondrial dysfunction governs immunometabolism in leukocytes of patients with acute-on-chronic liver failure. J Hepatol. 2022 Jan;76(1):93-106. doi: 10.1016/j.jhep.2021.08.009. Epub 2021 Aug 25. PMID: 34450236.
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Showing 1 to 6 of 6 entries